$349 Find Cheap Flights from Mississippi to South Dakota - Compare and Save

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1 adult, Economy, 0 bags

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Low season

January

Cheapest flight

$349
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Gulfport to Sioux Falls

FAQs for booking flights from Mississippi to South Dakota

  • How does KAYAK find such low prices on flights from Mississippi to South Dakota?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mississippi to South Dakota.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mississippi to South Dakota?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Mississippi to South Dakota is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mississippi to South Dakota?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Mississippi to South Dakota with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mississippi to South Dakota?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Mississippi to South Dakota up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in South Dakota?

    There are 5 airports in South Dakota. The busiest airport is Sioux Falls Joe Foss Field Airport (FSD), with 61% of all flights arriving there.

  • How long is the flight to South Dakota?

    An average nonstop flight from Mississippi to South Dakota takes 9h 09m, covering a distance of 1044 miles. The shortest route is Memphis (MEM) to Sioux Falls (FSD) with an average flight time of 4h 46m.

  • What are the most popular destinations in South Dakota?

    Based on KAYAK flight searches, the most popular destination is Sioux Falls (51% of total searches to South Dakota). The next most popular destination is Rapid City (49%).

Reviews of the top airline flying from Mississippi to South Dakota

 
Need help choosing which airline to fly with from Mississippi to South Dakota? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
American AirlinesOverall score based on 12168 reviews
7.9Crew
6.4Food
7.2Comfort
7.4Boarding
6.8Entertainment
Airline reviews

Multiple delays and made us miss the connecting flight and lost our bags

2.0 MediocreKhaled, Oct 2026
Read more American Airlines reviews

Multiple delays and made us miss the connecting flight and lost our bags

Cabin was bone dry, no humidity whatsoever, and pretty warm; and beverage service didn't start for at least an hour. I had to go to the back for water and the FAs tried telling me it was always this way for all Miami flights, which is complete nonsense. Avoid the MAX8 like the plague.

Business class flight attendant was very good. But our flight was delayed two hours for a “mechanical” bathroom issue that literally took 5 minutes to fix. Our plane landed early from its previous flight but still waited for a mechanic to show up to fix an obvious minor issue for almost three hours. This caused us to miss our connecting flight. They put us up in a Days Inn that was 17 miles away from the airport that took a half hour of driving just to get to and this was at 11pm at night. Then when we finally got back on a plane after a full day delay they left our luggage back in the airport. This was an international flight, so no luggage or belongings after flying 8 hours to a different country. We will NEVER fly American Airlines again.

12 hour wait in pdx to my initial flight to Dallas to hunstville

I was able to enlist on standby for an earlier flight, and eventually made it (last row). However, the experience was poor and felt unfair. On the standby list, I was ranked #2 (#1 had been cleared a seat). The person ranked as #3, who was also in the queue alongside me was given a seat much earlier - with group 4 boarding (a seat within the first 2 rows after business class). When inquired about why I was skipped-over on the priority list, the gate agent first paused (likely cuz she couldn't explain) - and then gave me the standard expectation that if a space opens up, she'll give me the seat. Despite my priority ranking being higher, I was unduly held-back, and could have missed the plane - unfairly giving advantage to someone else. Luckily one seat opened up; but given the unfair assignment of standby seat by gate-agent, this was a subpar boarding experience.

The airline was small and the seats were not comfortable to sit in for that length of time.

The flight attendants were very friendly, efficient, and helpful. The plane was ahead of schedule, and it all went very smoothly. Thank you.

I have a gluten allergy so did have any food

Wonderful crew and early arrival to our destination. It was so nice to have free wifi access and movies too. Thank you!

American Airlines gets worse every time I fly them. This is the 3rd time they lost my bags in a year. I also think their employees do not care when I communicate that I’m unsatisfied with the airlines. I’m a credit card holder, fly first class, and an advantage member but I think that I’m finally going to make the switch to Delta.

More options for your flight to South Dakota

Complete your trip to South Dakota with a hotel stay or car rental