MYR - BUF

$145 Find Cheap Flights from Myrtle Beach to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$248
Overall average: $346
Multiple Airlines
Wed 3/4Mon 3/9
MYR - BUF • 2 stops
Cheapest one-way
$145
Typical prices: $169-$218
Multiple Airlines
Sun 5/10
MYR - BUF • 2 stops
Top airlines
Southwest
Cheapest • from $321 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $268 (round-trip)
Nashville (BNA)
Shortest trip • 3h 55m (one-way)
Insights
Insights
Insights
Insights
When to travel
January
Cheapest • 21% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Wed, Mar 4 - Mon, Mar 9
Multiple Airlines Logo
9:09 am - 12:54 pm
MYR
-
BUF
27h 45m
2 stops
Multiple Airlines Logo
9:25 pm - 11:44 am
BUF
-
MYR
14h 19m
1 stop
$248Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
10:27 am - 10:07 am
MYR
-
BUF
23h 40m
1 stop
Multiple Airlines Logo
4:07 pm - 10:00 am
BUF
-
MYR
17h 53m
1 stop
$291Multiple Airlines
Thu, May 7 - Mon, May 11
Multiple Airlines Logo
12:50 pm - 7:13 pm
MYR
-
BUF
6h 23m
1 stop
Multiple Airlines Logo
8:08 pm - 11:50 am
BUF
-
MYR
15h 42m
2 stops
$304Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
12:50 pm - 10:07 am
MYR
-
BUF
21h 17m
1 stop
Multiple Airlines Logo
12:32 pm - 9:00 pm
BUF
-
MYR
8h 28m
2 stops
$314Multiple Airlines
Thu, May 7 - Mon, May 11
Southwest Logo
7:20 pm - 11:20 pm
MYR
-
BUF
4h 00m
1 stop
Southwest Logo
4:00 pm - 8:50 pm
BUF
-
MYR
4h 50m
1 stop
$321Southwest
Fri, Mar 27 - Tue, Mar 31
United Airlines Logo
6:05 pm - 11:56 pm
MYR
-
BUF
5h 51m
1 stop
United Airlines Logo
7:00 am - 2:17 pm
BUF
-
MYR
7h 17m
1 stop
$332United Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
9:14 am - 4:32 pm
MYR
-
BUF
7h 18m
2 stops
American Airlines Logo
5:00 am - 12:16 pm
BUF
-
MYR
7h 16m
1 stop
$333American Airlines
Fri, Mar 27 - Tue, Mar 31
Delta Logo
12:28 pm - 4:51 pm
MYR
-
BUF
4h 23m
1 stop
Delta Logo
2:59 pm - 12:04 am
BUF
-
MYR
9h 05m
2 stops
$337Delta
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
9:14 am - 4:32 pm
MYR
-
BUF
7h 18m
2 stops
American Airlines Logo
5:32 pm - 11:57 pm
BUF
-
MYR
6h 25m
2 stops
$339American Airlines
Wed, Apr 29 - Sun, May 3
Southwest Logo
7:35 am - 3:20 pm
MYR
-
BUF
7h 45m
2 stops
Southwest Logo
12:25 pm - 7:20 pm
BUF
-
MYR
6h 55m
2 stops
$342Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is January, where tickets cost $290 (return) on average. On the other hand, the most expensive months are February and December, where the average cost of round-trip tickets is $476 and $462 respectively.

Good to know

Low seasonDecember
Cheapest flight$145
Best time to beat the crowds but there is an average 25% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Buffalo was $145 for a one-way ticket and $304 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $375 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $346 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4300 reviews
8.1Boarding
8.0Comfort
7.0Food
8.6Crew
7.5Entertainment
Airline reviews

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

10.0 ExcellentTy&Steph, Feb 2026
CLT - STL
Read more Southwest reviews

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

The Southwest experience has definitely taken a dive from its early days. You can no longer deferentiate from other airlines. Air travel is too expensive. Southwest is no longer budget friendly. They have lost me as a loyal customer.

Flight was hours late, unable to sit next to spouse, I have had so much better experiences. Substantially better, only saving grace was that it was a short flight.

An entire day of delays. Cost lots of money. Meals and a hotel.

The WiFi and crew on the plane were good, however, the boarding experience was awful. I paid for the Choice Preferred and was boarded in group 5 so all overhead storage was full. They found room for our luggage, but further back making getting off the plane a nightmare. Also, we were in row 6 and the seats were extremely uncomfortable. Both my daughter and I had no leg room and couldn’t wait to get off the plane.

The charges were ridiculous for an hour flight and the turbulence was very scary.

Still need to work out the kinks on the new assigned seating boarding process. Otherwise, a very good flight.

WiFi did not work. Boarding with the new seating assignments took too long. The temperature in the terminal was obnoxious. +/- 80°

The seats are now more narrow. I paid for front row the seats in the front are even more narrow than before.

Only downside was the legroom and seat width, which is always a problem unless I spend more for a premium seat.

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

The smell from the bathroom kept wafting through the cabin. It made people sick.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

It was good. But the gate team made me check my carry on when there was plenty of space for my luggage on the plane. Otherwise our trip was fine.

Bags took over and hour to come out. Delays due to wind caused rebooking.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Everything you need to know for your flight from Myrtle Beach to Buffalo

Information on your arrival and departure airports