MYR - BUF

$127 Find Cheap Flights from Myrtle Beach to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$223
Overall average: $441
Delta
Tue 2/24Tue 3/3
MYR - BUF • 1 stop
Cheapest one-way
$127
Typical prices: $263-$292
Multiple Airlines
Sat 2/21
MYR - BUF • 1 stop
When to travel
September
Cheapest • 22% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Tue, Feb 24 - Tue, Mar 3
Delta Logo
6:00 am - 11:00 am
MYR
-
BUF
5h 00m1 stop
Delta Logo
6:01 am - 11:35 am
BUF
-
MYR
5h 34m1 stop
$223Delta
Wed, Feb 25 - Mon, Mar 2
Multiple Airlines Logo
10:09 am - 11:34 am
MYR
-
BUF
25h 25m2 stops
Multiple Airlines Logo
11:37 am - 11:44 am
BUF
-
MYR
24h 07m1 stop
$226Multiple Airlines
Tue, Feb 24 - Tue, Mar 3
Delta Logo
6:00 am - 2:08 pm
MYR
-
BUF
8h 08m2 stops
Delta Logo
6:45 pm - 11:57 pm
BUF
-
MYR
5h 12m1 stop
$228Delta
Tue, Feb 24 - Tue, Mar 3
Delta Logo
6:00 am - 2:08 pm
MYR
-
BUF
8h 08m2 stops
Delta Logo
3:39 pm - 11:57 pm
BUF
-
MYR
8h 18m2 stops
$234Delta
Wed, Feb 25 - Thu, Mar 5
Multiple Airlines Logo
10:09 am - 11:34 am
MYR
-
BUF
25h 25m2 stops
Multiple Airlines Logo
11:17 am - 11:43 am
BUF
-
MYR
24h 26m1 stop
$242Multiple Airlines
Mon, Feb 23 - Wed, Mar 4
Delta Logo
6:55 pm - 11:27 pm
MYR
-
BUF
4h 32m1 stop
Delta Logo
6:01 am - 11:35 am
BUF
-
MYR
5h 34m1 stop
$247Delta
Thu, Feb 26 - Thu, Mar 5
Multiple Airlines Logo
12:39 pm - 9:57 am
MYR
-
BUF
21h 18m1 stop
Multiple Airlines Logo
11:17 am - 11:43 am
BUF
-
MYR
24h 26m1 stop
$250Multiple Airlines
Tue, Feb 24 - Thu, Mar 5
Delta Logo
10:31 am - 10:39 pm
MYR
-
BUF
12h 08m2 stops
Delta Logo
6:45 pm - 11:57 pm
BUF
-
MYR
5h 12m1 stop
$252Delta
Thu, Feb 26 - Tue, Mar 3
Delta Logo
6:00 am - 4:58 pm
MYR
-
BUF
10h 58m2 stops
Delta Logo
11:52 am - 11:57 pm
BUF
-
MYR
12h 05m2 stops
$258Delta
Sat, Feb 28 - Wed, Mar 4
Delta Logo
6:00 am - 1:03 pm
MYR
-
BUF
7h 03m1 stop
Delta Logo
6:01 am - 11:35 am
BUF
-
MYR
5h 34m1 stop
$260Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is September, where tickets cost $292 (return) on average. On the other hand, the most expensive months are December and February, where the average cost of round-trip tickets is $462 and $441 respectively.

Good to know

Low seasonDecember
Cheapest flight$127
Best time to beat the crowds but there is an average 22% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Buffalo was $127 for a one-way ticket and $223 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $409 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $337 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4250 reviews
8.1Boarding
8.6Crew
8.0Comfort
7.0Food
7.5Entertainment
Airline reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

2.0 MediocreMatthew, Jan 2026
DAL - SAN
Read more Southwest reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Flight was fine other than there was a gate change that I was not notified of. By chance I happened to check my phone and saw the change, otherwise, we would have missed our connecting flight.

Haven’t flown on SW in years. Flight was on time departing and arriving. Served vegan butter onion flavored pretzels which were bad. Coke served was in a tiny paper cup. Crew was not engaging. Felt like they were going through the motions. Old plane, tight seats and no leg room.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Okay, not wonderful. Short flight. Wi-fi didn't work properly. Stuck waiting for a gate to open upon arrival for 20 or so minutes.

They sent a notice that they were boarding an hour early. We had to leave the club and run to the gate. They said sorry, that came from corporate and was a mistake. They did not have enough seating because the flight before it had not taken off on time. They moved our gate and delayed it for an hour.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Whenever a passenger purchase a ticket his advantage number should automatically to his information. It's not everyone remember the number. You request for your number and American airline agent say they will email it....and they never email anything and you loose your mileage just because you don't remember your number. It should automatically go your information and associate with your email account at all times

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Would have thought that they would gas up plane before everyone got on board

Flight was empty so had a whole row to myself. Still had to wait to get the bag due to the negligence at Palm Springs departure.

I flew out of Reagan National. My flight was delayed, delayed, delayed, and then canceled ...THREE TIMES over TWO DAYS. Staff were seemingly not empowered to provide information on why the flights were screwed up. A real nightmare.

Everything you need to know for your flight from Myrtle Beach to Buffalo

Information on your arrival and departure airports