MYR - BUF

$161 Find Cheap Flights from Myrtle Beach to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$297
Overall average: $441
Southwest
Wed 2/11Wed 2/18
MYR - BUF • 1 stop
Cheapest one-way
$146
Typical prices: $183-$281
Multiple Airlines
Wed 1/28
MYR - BUF • 2 stops
Top airlines
Southwest
Cheapest • from $297 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 22% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Wed, Feb 11 - Wed, Feb 18
Southwest Logo
5:55 pm - 9:55 pm
MYR
-
BUF
4h 00m
1 stop
Southwest Logo
3:45 pm - 7:45 pm
BUF
-
MYR
4h 00m
1 stop
$297Southwest
Wed, Feb 11 - Wed, Feb 18
Southwest Logo
11:05 am - 9:55 pm
MYR
-
BUF
10h 50m
2 stops
Southwest Logo
3:45 pm - 7:45 pm
BUF
-
MYR
4h 00m
1 stop
$302Southwest
Tue, May 5 - Tue, May 12
Southwest Logo
6:10 pm - 10:15 pm
MYR
-
BUF
4h 05m
1 stop
Southwest Logo
6:05 am - 10:35 am
BUF
-
MYR
4h 30m
1 stop
$303Southwest
Wed, Feb 11 - Wed, Feb 18
Delta Logo
4:00 pm - 10:57 pm
MYR
-
BUF
6h 57m
2 stops
Delta Logo
3:39 pm - 11:57 pm
BUF
-
MYR
8h 18m
2 stops
$308Delta
Mon, Mar 2 - Wed, Mar 4
Southwest Logo
6:40 pm - 10:30 pm
MYR
-
BUF
3h 50m
1 stop
Southwest Logo
3:45 pm - 7:45 pm
BUF
-
MYR
4h 00m
1 stop
$311Southwest
Wed, Feb 18 - Wed, Feb 25
American Airlines Logo
10:26 am - 4:52 pm
MYR
-
BUF
6h 26m
2 stops
American Airlines Logo
4:04 pm - 10:56 pm
BUF
-
MYR
6h 52m
2 stops
$314American Airlines
Mon, Mar 2 - Wed, Mar 4
Delta Logo
6:55 pm - 11:27 pm
MYR
-
BUF
4h 32m
1 stop
Delta Logo
11:52 am - 11:57 pm
BUF
-
MYR
12h 05m
2 stops
$316Delta
Mon, Mar 2 - Wed, Mar 4
Delta Logo
6:00 am - 4:58 pm
MYR
-
BUF
10h 58m
2 stops
Delta Logo
2:58 pm - 11:57 pm
BUF
-
MYR
8h 59m
2 stops
$322Delta
Thu, Mar 12 - Sun, Mar 15
Southwest Logo
8:05 pm - 12:10 am
MYR
-
BUF
4h 05m
1 stop
Southwest Logo
12:40 pm - 7:30 pm
BUF
-
MYR
6h 50m
1 stop
$346Southwest
Thu, Mar 12 - Sun, Mar 15
Southwest Logo
3:35 pm - 12:10 am
MYR
-
BUF
8h 35m
2 stops
Southwest Logo
12:40 pm - 7:30 pm
BUF
-
MYR
6h 50m
1 stop
$351Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is September, where tickets cost $292 (return) on average. On the other hand, the most expensive months are December and February, where the average cost of round-trip tickets is $462 and $441 respectively.

Good to know

Low seasonDecember
Cheapest flight$146
Best time to beat the crowds but there is an average 22% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Buffalo was $146 for a one-way ticket and $297 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $402 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $340 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4266 reviews
7.5Entertainment
8.1Boarding
8.0Comfort
7.0Food
8.6Crew
Airline reviews

Great flight but super high price. Glad it was a business trip and not personal

10.0 ExcellentPieter, Jan 2026
LGB - DAL
Read more Southwest reviews

Great flight but super high price. Glad it was a business trip and not personal

On time. Friendly staff. Took to long to pre bord all the specialty groups. Cramped small plane

The seats were comfortable, and the boarding process was pretty smooth.

3 hour delay. Had to change plans and was still delayed.

The staff was very friendly, professional, and courteous. The overall flight was a great experience.

The crew canceled the complementary snack and drink in anticipation of turbulence that never materialized. I was counting on the drink (water) to take the the doses of medication - prescribed for my heart condition - that were due during the flight. Since no snack or meal was served on this flight, I cannot rate the food quality. Otherwise, this flight was excellent.

Departure was delayed more than 1/2 hour while we waited for luggage (only) transfer from another flight/plane. Once approved for takeoff, the flight was excellent.

We got exit row seats both flights. Everything was running on time

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

It was good. But the gate team made me check my carry on when there was plenty of space for my luggage on the plane. Otherwise our trip was fine.

Bags took over and hour to come out. Delays due to wind caused rebooking.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Whenever a passenger purchase a ticket his advantage number should automatically to his information. It's not everyone remember the number. You request for your number and American airline agent say they will email it....and they never email anything and you loose your mileage just because you don't remember your number. It should automatically go your information and associate with your email account at all times

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Everything you need to know for your flight from Myrtle Beach to Buffalo

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