MYR - BUF

$107 Find Cheap Flights from Myrtle Beach to Buffalo - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$214
Typical prices: $266-$409
American Airlines
Wed 8/5Wed 8/12
MYR - BUF • 1 stop
Cheapest one-way
$107
Typical prices: $188-$304
Southwest
Tue 8/18
MYR - BUF • 1 stop
Top airlines
American Airlines
Cheapest • from $214 (round-trip)
Southwest
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Nashville (BNA)
Cheapest • Avg $334 (round-trip)
Detroit (DTW)
Shortest trip • 3h 49m (one-way)
Insights
Insights
Insights
Insights
When to travel
September
Cheapest • 37% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Wed, Aug 5 - Wed, Aug 12
American Airlines Logo
7:20 pm - 11:56 pm
MYR
-
BUF
4h 36m
1 stop
American Airlines Logo
6:59 pm - 10:38 pm
BUF
-
MYR
3h 39m
1 stop
$214American Airlines
Fri, Aug 7 - Wed, Aug 12
American Airlines Logo
5:15 pm - 9:55 pm
MYR
-
BUF
4h 40m
1 stop
American Airlines Logo
5:00 am - 10:49 am
BUF
-
MYR
5h 49m
1 stop
$240American Airlines
Fri, Aug 7 - Fri, Aug 14
American Airlines Logo
5:15 pm - 9:55 pm
MYR
-
BUF
4h 40m
1 stop
American Airlines Logo
4:49 pm - 10:38 pm
BUF
-
MYR
5h 49m
1 stop
$267American Airlines
Sat, Aug 8 - Fri, Aug 14
American Airlines Logo
7:20 pm - 11:56 pm
MYR
-
BUF
4h 36m
1 stop
American Airlines Logo
4:18 pm - 8:55 pm
BUF
-
MYR
4h 37m
1 stop
$268American Airlines
Fri, Sep 4 - Fri, Sep 11
American Airlines Logo
6:00 am - 10:18 am
MYR
-
BUF
4h 18m
1 stop
American Airlines Logo
12:56 pm - 6:45 pm
BUF
-
MYR
5h 49m
1 stop
$269American Airlines
Wed, Sep 30 - Sun, Oct 4
Southwest Logo
8:15 am - 12:30 pm
MYR
-
BUF
4h 15m
1 stop
Southwest Logo
9:00 am - 3:25 pm
BUF
-
MYR
6h 25m
1 stop
$283Southwest
Wed, Sep 30 - Sun, Oct 4
Southwest Logo
8:15 am - 12:30 pm
MYR
-
BUF
4h 15m
1 stop
Southwest Logo
4:05 pm - 10:40 pm
BUF
-
MYR
6h 35m
2 stops
$289Southwest
Wed, Sep 30 - Sun, Oct 4
Southwest Logo
7:50 am - 5:45 pm
MYR
-
BUF
9h 55m
2 stops
Southwest Logo
4:05 pm - 10:40 pm
BUF
-
MYR
6h 35m
2 stops
$294Southwest
Thu, Oct 1 - Sun, Oct 4
Southwest Logo
6:15 am - 4:10 pm
MYR
-
BUF
9h 55m
2 stops
Southwest Logo
4:05 pm - 10:00 pm
BUF
-
MYR
5h 55m
1 stop
$298Southwest
Thu, Oct 1 - Sun, Oct 4
Southwest Logo
6:15 am - 4:10 pm
MYR
-
BUF
9h 55m
2 stops
Southwest Logo
12:20 pm - 10:00 pm
BUF
-
MYR
9h 40m
2 stops
$303Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is September, where tickets cost $249 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $584 and $507 respectively.

Find deals

Good to know

Low seasonMarch
Cheapest flight$107
Best time to beat the crowds but there is an average 46% increase in price.
Most popular time to fly with an average 12% increase in price.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 5 days, the lowest price for a flight from Myrtle Beach to Buffalo was $107 for a one-way ticket and $214 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $380 and an overall rating of 7.9, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $372 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4248 reviews
7.5Entertainment
7.0Food
8.0Comfort
8.6Crew
8.1Boarding
Airline reviews

Had a great flight. Delayed takeoff, but comfortable. Snacks were good.

10.0 ExcellentMelissa, Mar 2026
MSY - LGA
Read more Southwest reviews

Had a great flight. Delayed takeoff, but comfortable. Snacks were good.

Pretty seamless, just a tad bit late in taking off and landing.

after landing, we stay 2 hours on the taxi way before reaching the gate The airline and the crew were good though

My flight to Chicago left and landed early. My return flight left two minutes late and arrived 2 minutes late. My seat selections were ideal! There were no snacks going to Chicago and no snacks on the return trip. There are no charging outlets on board.

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

The fluidity of the entire process of boarding the plane the flight attendants attentiveness. The flight attendants also provided coloring books for my kids who loved it.

It good. Just not that plane didn’t have power outlets to charge devices etc.

I think Southwest can offer a whole can of beverage instead of such a small cup

We stood on the tarmac for over an hour. Very bad turbulence the whole ride. Very to get to the restroom.

C Am handicapped and couldn't get help with my luggage.

Flight canceled because they didn’t have enough flight attendants. No refunds or credits for future flights

Boarding was awful - no order, people cutting in line, completely chaotic Planes are very old and uncomfortable. Noticeable difference between Delta and United on same route.

The plane was spartan, the seats not that comfortable. It was like flying a super low budget airline. They charged for coffee!!! I have never, ever experienced that before.

Terrible boarding and first class experience. Nice staff but overall disorganized, dirty plane.

I almost missed my flight and they helped me out enormously

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

Flight was delayed 5 hours causing me to miss my connecting flights

We liked quick boarding and on time departure. Seats were very uncomfortable.

It was quick, plane was loaded and the service on board was ok

Everything you need to know for your flight from Myrtle Beach to Buffalo

Information on your arrival and departure airports

Myrtle Beach (MYR)
Buffalo (BUF)