MYR - BUF

$140 Find Cheap Flights from Myrtle Beach to Buffalo - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$320
Typical prices: $550-$195
Southwest
Mon 9/14Wed 9/16
MYR - BUF • 1 stop
Cheapest one-way
$140
Typical prices: $144-$223
Multiple Airlines
Sat 7/11
MYR - BUF • 2 stops
Top airlines
Cheapest • from $320 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $334 (round-trip)
Shortest trip • 3h 49m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 37% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Mon, Sep 14 - Wed, Sep 16
Southwest Logo
6:40 am - 11:10 am
MYR
-
BUF
4h 30m
1 stop
Southwest Logo
3:00 pm - 7:10 pm
BUF
-
MYR
4h 10m
1 stop
$320Southwest
Mon, Sep 14 - Wed, Sep 16
Southwest Logo
6:15 pm - 9:50 pm
MYR
-
BUF
3h 35m
1 stop
Southwest Logo
8:55 am - 7:20 pm
BUF
-
MYR
10h 25m
2 stops
$325Southwest
Tue, Jul 7 - Thu, Jul 16
American Airlines Logo
6:45 pm - 11:53 pm
MYR
-
BUF
5h 08m
1 stop
American Airlines Logo
1:47 pm - 8:03 pm
BUF
-
MYR
6h 16m
1 stop
$328American Airlines
Mon, Sep 14 - Wed, Sep 16
Southwest Logo
1:55 pm - 9:50 pm
MYR
-
BUF
7h 55m
2 stops
Southwest Logo
8:55 am - 7:20 pm
BUF
-
MYR
10h 25m
2 stops
$330Southwest
Fri, Jul 10 - Wed, Jul 15
Multiple Airlines Logo
9:30 pm - 10:29 am
MYR
-
BUF
36h 59m
2 stops
Multiple Airlines Logo
7:57 pm - 8:55 am
BUF
-
MYR
12h 58m
1 stop
$331Multiple Airlines
Fri, Jul 10 - Tue, Jul 21
Multiple Airlines Logo
9:30 pm - 10:29 am
MYR
-
BUF
36h 59m
2 stops
Multiple Airlines Logo
9:09 pm - 9:05 am
BUF
-
MYR
11h 56m
1 stop
$332Multiple Airlines
Sun, Jul 19 - Sat, Jul 25
American Airlines Logo
7:43 am - 12:02 pm
MYR
-
BUF
4h 19m
1 stop
American Airlines Logo
7:36 pm - 11:51 pm
BUF
-
MYR
4h 15m
1 stop
$338American Airlines
Tue, Jul 7 - Thu, Jul 16
Multiple Airlines Logo
4:13 pm - 7:06 pm
MYR
-
BUF
26h 53m
1 stop
Multiple Airlines Logo
11:29 am - 8:01 am
BUF
-
MYR
44h 32m
2 stops
$342Multiple Airlines
Thu, Sep 3 - Mon, Sep 7
American Airlines Logo
11:02 am - 4:54 pm
MYR
-
BUF
5h 52m
1 stop
American Airlines Logo
4:49 pm - 10:38 pm
BUF
-
MYR
5h 49m
1 stop
$345American Airlines
Thu, Aug 27 - Sun, Aug 30
Multiple Airlines Logo
6:28 pm - 1:55 pm
MYR
-
BUF
19h 27m
2 stops
Multiple Airlines Logo
8:57 pm - 7:50 am
BUF
-
MYR
10h 53m
1 stop
$351Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to Buffalo?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to Buffalo departing in September.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is September, where tickets cost $249 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $584 and $507 respectively.

Good to know

Low seasonMarch
Cheapest flight$140
Best time to beat the crowds but there is an average 48% increase in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 5 days, the lowest price for a flight from Myrtle Beach to Buffalo was $140 for a one-way ticket and $320 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $376 and an overall rating of 7.9, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $359 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4235 reviews
8.0Comfort
7.5Entertainment
8.1Boarding
7.0Food
8.6Crew
Airline reviews

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

2.0 MediocreMatthew, Jun 2026
CVG - MDW
Read more Southwest reviews

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

It was great. The gate staff were very helpful in Portland when my son forgot his rolling bag and had to go back to get it just in time to make it on the plane. We really appreciate that. Great job!

Airline is not very senior friendly. Flights are late, forcing us to run to the connecting flight. Food is awful. Wish they would go back to pretzels and peanuts. During flight, pressurization isn’t quite right and all of our ears get plugged. Everything is nickel and dime, charging for boarding, seat selection and legroom. While a screen at the desk in the gate area says check your roll on bag now for free due to space limitation, the employee at the desk will not check the bag without a $100 fee. Insane.

Kayak could’ve posted the correct gate number. Almost missed my flight.

Slow boarding, limited food and drink portions. Bad delays and turbulence

there were two flight attendants that were up front...that were the best! They get KUDOs for making my trip only fantastic. Tell them Jeff said that!

OKay. I sat in the back of the plane and it was really loud between babies and little kids, and adults who.like to talk a lot and loudly most of the flight.

Flight coming out of Buffalo was delayed, so we had to be rescheduled on another flight from Baltimore to Phoenix which means we had a long layover and got home 3.5 hours late. Shuttle to parking stopped at 10pm, so we had to pay for an Uber to the parking lot and got charged an extra day of parking since it was after midnight. Not the best experience. Long day!

Was fine, delayed and feels like southwest is always late

I don't know why flying out of Sarasota requires two plane changes.

Agency very bad had to cancelled my booking too many changes in the flight changed my flight to 1 week

Our flight from JFK to Madrid was delayed. We had to go from one side of the Madrid airport (Terminal 4s to the far end of terminal 4 - Gate K98) to our gate in less than 30 minutes. Put passport control and security/baggage check and that’s very hard unless you’re Usain Bolt. I called Iberia Airlines and the telephone customer service told me that I was going to have to pay to re-book. Luckily the help desk in the airport (who was dealing with dozens of people from the same JFK-Madrid flight) did not charge us extra to reschedule to a flight 8 hours later. They also gave us a voucher for breakfast and lunch. Glad the actual person at the airport had some actual sense.

Our flight was repeatedly delayed for maintenance problems: scheduled for 9.30am, eventually delayed to 7pm! Very very inconvenient! AA should have provided a substitute plane much earlier.. On the other hand, Customer Service crew in Charlotte helped us to reach NY (LGA) by late afternoon. Thank you Patricia!! The actual flight was quick and very comfortable. As always a. excellent, professional crew. [no food on a a short hop).

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Boarding gate at LAX was too crowded—two gates next to one another

It was really a terrific experience both going and returning on AA. Staff and crew were professional.

This short sector between Miami and JFK was undertaken purely for business purposes, with efficiency as the primary objective rather than a full inflight experience. Overall, the journey met its intended purpose; however, the ground experience at Miami stood out significantly. During check-in, I was unable to link my frequent flyer details from Qatar Airways (oneworld alliance) through either the self-service kiosk or web check-in. The situation was handled exceptionally well by the check-in agent, who demonstrated remarkable ownership. She coordinated across multiple counters, ensured my frequent flyer number was correctly reflected, reissued the boarding pass, and confirmed that mileage accrual would be recognized. Additionally, she ensured the boarding pass reflected priority status, enabling a seamless priority check-in experience without delays. This level of proactive service was both commendable and impactful. Boarding and the inflight experience, operated by American Airlines under a codeshare arrangement, were efficient but largely transactional. While operational delivery was smooth, there was no visible recognition of oneworld frequent flyer status onboard. In comparison to the consistently personalized engagement typically experienced with Qatar Airways, this absence was noticeable—though understandably a potential limitation of codeshare alignment rather than a direct service shortfall. In summary, while the flight itself fulfilled its operational intent, the exceptional professionalism and commitment demonstrated at the Miami check-in counter was the defining highlight of this journey. Greater consistency in elite recognition across partner airlines would further enhance the overall experience.

I almost missed my flight and they helped me out enormously

Flight was fine, but not having WiFi was a major negative

Everything you need to know for your flight from Myrtle Beach to Buffalo

Information on your arrival and departure airports