MYR - BUF

$157 Find Cheap Flights from Myrtle Beach to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$319
Overall average: $360
American Airlines
Mi 4/8Mi 4/15
MYR - BUF • 1 stop
Cheapest one-way
$157
Typical prices: $148-$150
Multiple Airlines
Mo 4/20
MYR - BUF • 2 stops
Top airlines
Cheapest • from $319 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $268 (round-trip)
Shortest trip • 3h 50m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 24% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Mi, Apr 8 - Mi, Apr 15
American Airlines Logo
7:20 pm - 11:19 pm
MYR
-
BUF
3h 59m
1 stop
American Airlines Logo
5:00 am - 12:16 pm
BUF
-
MYR
7h 16m
1 stop
$319American Airlines
Sa, Mai 23 - Di, Mai 26
Southwest Logo
7:15 pm - 11:25 pm
MYR
-
BUF
4h 10m
1 stop
Southwest Logo
4:00 pm - 8:30 pm
BUF
-
MYR
4h 30m
1 stop
$326Southwest
Sa, Mai 23 - Di, Mai 26
Southwest Logo
5:05 pm - 11:25 pm
MYR
-
BUF
6h 20m
2 stops
Southwest Logo
6:05 am - 10:35 am
BUF
-
MYR
4h 30m
1 stop
$331Southwest
Mo, Mai 4 - Mo, Mai 11
Delta Logo
6:00 am - 11:01 am
MYR
-
BUF
5h 01m
1 stop
Delta Logo
6:25 am - 10:37 am
BUF
-
MYR
4h 12m
1 stop
$333Delta
Mi, Apr 8 - Mi, Apr 15
American Airlines Logo
5:00 am - 11:58 am
MYR
-
BUF
6h 58m
2 stops
American Airlines Logo
10:44 am - 6:00 pm
BUF
-
MYR
7h 16m
1 stop
$359American Airlines
Do, Mai 28 - Sa, Mai 30
Delta Logo
11:43 am - 6:44 pm
MYR
-
BUF
7h 01m
1 stop
Delta Logo
6:25 am - 10:37 am
BUF
-
MYR
4h 12m
1 stop
$360Delta
Do, Mai 14 - Mo, Mai 18
Multiple Airlines Logo
3:53 pm - 6:46 pm
MYR
-
BUF
26h 53m
1 stop
Multiple Airlines Logo
7:31 pm - 7:33 pm
BUF
-
MYR
24h 02m
2 stops
$362Multiple Airlines
Mo, Mai 4 - Mo, Mai 11
American Airlines Logo
10:28 am - 5:02 pm
MYR
-
BUF
6h 34m
1 stop
American Airlines Logo
5:32 pm - 11:57 pm
BUF
-
MYR
6h 25m
2 stops
$366American Airlines
Mi, Jun 24 - Mo, Jun 29
Delta Logo
6:00 am - 3:30 pm
MYR
-
BUF
9h 30m
1 stop
Delta Logo
6:00 am - 2:57 pm
BUF
-
MYR
8h 57m
1 stop
$367Delta
Do, Mai 14 - Mo, Mai 18
Southwest Logo
3:45 pm - 11:20 pm
MYR
-
BUF
7h 35m
2 stops
Southwest Logo
5:00 am - 1:05 pm
BUF
-
MYR
8h 05m
2 stops
$370Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is January, where tickets cost $290 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $584 and $462 respectively.

Good to know

Low seasonMarch
Cheapest flight$157
Best time to beat the crowds but there is an average 52% increase in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Buffalo was $157 for a one-way ticket and $319 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $376 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $349 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4324 reviews
7.5Entertainment
8.6Crew
7.0Food
8.1Boarding
8.0Comfort
Airline reviews

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

10.0 ExcellentMartie, Mar 2026
LGB - BNA
Read more Southwest reviews

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

Boarding was easy. The seats are small and fairly uncomfortable

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

We had a 5 hour delay on the tarmac in Baltimore

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

The new seating arrangement is so over priced for what you get.

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

The crew was excellent and overall the flight was good. No complaints.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

The smell from the bathroom kept wafting through the cabin. It made people sick.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

Everything you need to know for your flight from Myrtle Beach to Buffalo

Information on your arrival and departure airports