MYR - BUF

$141 Find Cheap Flights from Myrtle Beach to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$249
Typical prices: $357-$263
Delta
Wed 8/26Mon 8/31
MYR - BUF • 1 stop
Cheapest one-way
$141
Typical prices: $159-$297
American Airlines
Sat 8/15
MYR - BUF • 1 stop
Top airlines
Cheapest • from $249 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $334 (round-trip)
Shortest trip • 3h 52m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 25% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Buffalo

Wed, Aug 26 - Mon, Aug 31
Delta Logo
11:00 am - 5:30 pm
MYR
-
BUF
6h 30m
1 stop
Delta Logo
6:40 am - 10:38 am
BUF
-
MYR
3h 58m
1 stop
$249Delta
Wed, Aug 26 - Mon, Aug 31
American Airlines Logo
11:02 am - 4:54 pm
MYR
-
BUF
5h 52m
1 stop
American Airlines Logo
5:00 am - 11:24 am
BUF
-
MYR
6h 24m
2 stops
$290American Airlines
Wed, Jul 8 - Wed, Jul 15
American Airlines Logo
4:16 pm - 10:51 pm
MYR
-
BUF
6h 35m
1 stop
American Airlines Logo
12:45 pm - 6:37 pm
BUF
-
MYR
5h 52m
1 stop
$319American Airlines
Wed, Jul 8 - Wed, Jul 15
American Airlines Logo
4:16 pm - 11:59 pm
MYR
-
BUF
7h 43m
2 stops
American Airlines Logo
12:45 pm - 6:37 pm
BUF
-
MYR
5h 52m
1 stop
$324American Airlines
Thu, Sep 10 - Sun, Sep 13
Delta Logo
6:45 pm - 11:58 pm
MYR
-
BUF
5h 13m
1 stop
Delta Logo
6:00 am - 10:09 am
BUF
-
MYR
4h 09m
1 stop
$334Delta
Fri, Aug 14 - Mon, Aug 31
American Airlines Logo
7:20 pm - 11:56 pm
MYR
-
BUF
4h 36m
1 stop
American Airlines Logo
4:49 pm - 10:38 pm
BUF
-
MYR
5h 49m
1 stop
$344American Airlines
Wed, Oct 7 - Mon, Oct 12
Southwest Logo
8:20 am - 2:50 pm
MYR
-
BUF
6h 30m
1 stop
Southwest Logo
12:25 pm - 7:30 pm
BUF
-
MYR
7h 05m
1 stop
$349Southwest
Thu, Sep 10 - Sun, Sep 13
Southwest Logo
10:50 am - 6:25 pm
MYR
-
BUF
7h 35m
2 stops
Southwest Logo
9:40 am - 2:10 pm
BUF
-
MYR
4h 30m
1 stop
$350Southwest
Tue, Oct 20 - Fri, Oct 23
Southwest Logo
8:20 am - 2:50 pm
MYR
-
BUF
6h 30m
1 stop
Southwest Logo
6:00 am - 10:15 am
BUF
-
MYR
4h 15m
1 stop
$353Southwest
Wed, Oct 7 - Mon, Oct 12
Southwest Logo
10:30 am - 10:05 pm
MYR
-
BUF
11h 35m
2 stops
Southwest Logo
11:55 am - 8:15 pm
BUF
-
MYR
8h 20m
1 stop
$355Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Buffalo flights

Get data-powered insights and trends into flights from Myrtle Beach to Buffalo to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to Buffalo?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to Buffalo departing in August.

What is the cheapest month to fly from Myrtle Beach to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Buffalo is January, where tickets cost $290 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $584 and $462 respectively.

Good to know

Low seasonMarch
Cheapest flight$141
Best time to beat the crowds but there is an average 51% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Myrtle Beach to Buffalo

When to book flights from Myrtle Beach to Buffalo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Buffalo

  • What is the cheapest flight from Myrtle Beach to Buffalo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Buffalo was $141 for a one-way ticket and $249 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Myrtle Beach to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Buffalo?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Buffalo.

  • Which is the best airline for flights from Myrtle Beach to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Buffalo are Southwest and American Airlines. With an average price for the route of $376 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $344 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4261 reviews
8.1Boarding
7.0Food
8.6Crew
8.0Comfort
7.5Entertainment
Airline reviews

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

4.0 OkayAnonymous, May 2026
MDW - LAX
Read more Southwest reviews

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

The flight was smooth. The Southwest experience has degraded overall, but this one was okay.

No gluten free snacks. Seats felt worn or bare bones even though it was a new 737 MAX 8.

One major problem that was very unprofessional and uncalled for. Plane landed and we had to wait 20 minutes to get off the plane since they were waiting for someone to come to the gate to drive the jetway. Southwest couldn't have someone available and waiting for the plane to land? Is there only one person in Hobby airport who knows to drive the jetway? Was he at lunch? In the bar? Uncomfortable and uncalled for!

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

I'm glad it wasn't only 75% full because I could get a good seat

if I was good. Not happy that I have to pay extra money to get the seat I need for lake room, but I guess that’s a sign of the times.

Seats were very comfortable. They tilted back. Drinks and snacks were free and served 3 times. Attendants were awesome.

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

Truly terrible. Will never willingly fly southwest again. Seats are worse than before they switched to assigned seating. One flight attendant was the opposite of helpful (rude, unhelpful, dismissive, and as my stranger seatmate said unprompted: a total prick). This caused me, 15 minutes into the flight, to book an alternate return flight home on a competing airline (first class 1.2k purchase instead of my existing planned flight) just so I would not have to ever be on that aircraft, with that terrible service person, with those horrific seats ever again.

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Boarding gate at LAX was too crowded—two gates next to one another

It was really a terrific experience both going and returning on AA. Staff and crew were professional.

This short sector between Miami and JFK was undertaken purely for business purposes, with efficiency as the primary objective rather than a full inflight experience. Overall, the journey met its intended purpose; however, the ground experience at Miami stood out significantly. During check-in, I was unable to link my frequent flyer details from Qatar Airways (oneworld alliance) through either the self-service kiosk or web check-in. The situation was handled exceptionally well by the check-in agent, who demonstrated remarkable ownership. She coordinated across multiple counters, ensured my frequent flyer number was correctly reflected, reissued the boarding pass, and confirmed that mileage accrual would be recognized. Additionally, she ensured the boarding pass reflected priority status, enabling a seamless priority check-in experience without delays. This level of proactive service was both commendable and impactful. Boarding and the inflight experience, operated by American Airlines under a codeshare arrangement, were efficient but largely transactional. While operational delivery was smooth, there was no visible recognition of oneworld frequent flyer status onboard. In comparison to the consistently personalized engagement typically experienced with Qatar Airways, this absence was noticeable—though understandably a potential limitation of codeshare alignment rather than a direct service shortfall. In summary, while the flight itself fulfilled its operational intent, the exceptional professionalism and commitment demonstrated at the Miami check-in counter was the defining highlight of this journey. Greater consistency in elite recognition across partner airlines would further enhance the overall experience.

I almost missed my flight and they helped me out enormously

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

THe flight was an hour late. You got us on the plan and we sat on the ground for 45 minutes with no information from the pilot whatsoever. Worst flight this year.

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

Everything you need to know for your flight from Myrtle Beach to Buffalo

Information on your arrival and departure airports