DSM - MYR

$113 Find Cheap Flights from Des Moines to Myrtle Beach

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Myrtle Beach departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Myrtle Beach

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Myrtle Beach, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Myrtle Beach, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Des Moines to Myrtle Beach (DSM-MYR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Myrtle Beach that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Myrtle Beach

Tue, Oct 7 - Tue, Oct 21
Delta Logo
10:52 am - 6:03 pmDSM-MYR
6h 11m1 stop
Delta Logo
11:29 am - 4:52 pmMYR-DSM
6h 23m1 stop
$237Delta
Find Deal
Tue, Oct 7 - Tue, Oct 21
Delta Logo
2:40 pm - 11:59 pmDSM-MYR
8h 19m2 stops
Delta Logo
12:20 pm - 7:20 pmMYR-DSM
8h 00m1 stop
$242Delta
Find Deal
Tue, Oct 7 - Tue, Oct 21
Delta Logo
2:40 pm - 11:59 pmDSM-MYR
8h 19m2 stops
Delta Logo
6:00 am - 1:59 pmMYR-DSM
8h 59m2 stops
$247Delta
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Thu, Nov 13 - Mon, Nov 17
American Airlines Logo
6:00 am - 12:13 pmDSM-MYR
5h 13m1 stop
American Airlines Logo
4:05 pm - 10:09 pmMYR-DSM
7h 04m1 stop
$249American Airlines
Find Deal
Fri, Sep 12 - Tue, Sep 16
 Logo
8:00 am - 6:41 pmDSM-MYR
9h 41m1 stop
 Logo
2:45 pm - 9:24 amMYR-DSM
19h 39m2 stops
Tue, Aug 26 - Sat, Aug 30
American Airlines Logo
7:34 am - 3:27 pmDSM-MYR
6h 53m1 stop
American Airlines Logo
5:03 pm - 11:17 pmMYR-DSM
7h 14m1 stop
$267American Airlines
Find Deal
Mon, Aug 18 - Mon, Aug 25
 Logo
6:00 am - 6:29 pmDSM-MYR
11h 29m1 stop
 Logo
6:45 am - 8:12 pmMYR-DSM
14h 27m1 stop
Thu, Nov 13 - Mon, Nov 17
Southwest Logo
8:00 am - 9:30 pmDSM-MYR
12h 30m2 stops
Southwest Logo
2:55 pm - 9:35 pmMYR-DSM
7h 40m2 stops
$289Southwest
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Fri, Oct 24 - Wed, Oct 29
Southwest Logo
6:35 am - 7:30 pmDSM-MYR
11h 55m2 stops
Southwest Logo
1:20 pm - 9:50 pmMYR-DSM
9h 30m2 stops
$295Southwest
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Wed, Aug 27 - Sat, Aug 30
United Airlines Logo
8:00 am - 2:31 pmDSM-MYR
5h 31m1 stop
United Airlines Logo
3:45 pm - 11:41 pmMYR-DSM
8h 56m1 stop
$307United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to Myrtle Beach flights

Get data-powered insights and trends into flights from Des Moines to Myrtle Beach to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to Myrtle Beach?

The average price of all round-trip flights from Des Moines to Myrtle Beach clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Myrtle Beach on a Tuesday and more expensive on a Thursday. On your return trip to Des Moines, you should consider flying back on a Tuesday, and avoid Thursdays for better deals.

What is the cheapest month to fly from Des Moines to Myrtle Beach?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Myrtle Beach, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Myrtle Beach is August, where tickets cost $276 (return) on average. On the other hand, the most expensive months are June and November, where the average cost of round-trip tickets is $472 and $467 respectively.

How far in advance should I book a flight from Des Moines to Myrtle Beach?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Myrtle Beach, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Myrtle Beach, you should book around 4 weeks before departure, which saves you about 51% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonDecember
Cheapest flight$113
Best time to beat the crowds but there is an average 19% increase in price.
Most popular time to fly and prices are also 17% lower on average.
Flight from Des Moines to Myrtle Beach

When to book flights from Des Moines to Myrtle Beach

Are your dates flexible? Find out the best times to travel from Des Moines to Myrtle Beach based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Myrtle Beach

  • What is the cheapest flight from Des Moines to Myrtle Beach?

    In the last 3 days, the lowest price for a flight from Des Moines to Myrtle Beach was $113 for a one-way ticket and $237 for a round-trip.

  • Do I need a passport to fly between Des Moines and Myrtle Beach?

    A passport is not required to fly from Des Moines to Myrtle Beach.

  • Which aircraft models fly most regularly from Des Moines to Myrtle Beach?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Myrtle Beach?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Des Moines and Myrtle Beach, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Myrtle Beach, Delta or Southwest?

    The two airlines most popular with KAYAK users for flights from Des Moines to Myrtle Beach are Delta and Southwest. With an average price for the route of $376 and an overall rating of 8.0, Delta is the most popular choice. Southwest is also a great choice for the route, with an average price of $404 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Des Moines to Myrtle Beach?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Myrtle Beach.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Myrtle Beach?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Myrtle Beach from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Myrtle Beach?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Myrtle Beach with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and MYR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Myrtle Beach?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Myrtle Beach from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Myrtle Beach

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Myrtle Beach. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Myrtle Beach? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4241 reviews
7.0Food
7.5Entertainment
8.0Comfort
8.1Boarding
8.6Crew
Airline reviews

southwest just starting charging for luggage. hadnt realized it until it was too late. now out $70 when i couldve bought a carry on if i wouldve known. free bags was one of the only reasons i chose southwest over another airline (the other being no assigned seats, which is apparently also being changed). stupid business decision. wont be flying southwest anymore.

2.0 MediocreAnonymous, Jul 2025AUS - RDU
Read more Southwest reviews

southwest just starting charging for luggage. hadnt realized it until it was too late. now out $70 when i couldve bought a carry on if i wouldve known. free bags was one of the only reasons i chose southwest over another airline (the other being no assigned seats, which is apparently also being changed). stupid business decision. wont be flying southwest anymore.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

WiFi did not work. For as outrageous as these flights cost, when they’re advertised with certain services/ features they should be in working order

Worst experience I had on Southwest. Still better than most, but the seating was barely tolerable.

The Southwest employees (all two of them) were very nice and cheerful despite the fact the line to self-check a bag (simply drop it off) was hundreds of people long. Thank God I arrived early to the airport because I stood in this line for at least an hour. Once on the flight that had been delayed by an hour, we had no Wi-Fi and thus no entertainment. Finally, I hope the investor strong arm tactics against Southwest pay off in a short-term windfall to your C-Suite because the rest of you are screwed. I have been a faithful Southwest customer for 15 years due to everything you just got rid of. I'm flying to Idaho and Washington in October, both places I used to simply book with Southwest without a second thought now with Frontier (Washington) and United (Idaho) because they offer everything the "new" Southwest does but cheaper and at better times, destinations, etc. This really makes me sad...

It was okay. The plane was delayed from earlier in the day, but they kept updating the departure time, sometimes later, sometimes earlier. That was stressful. Once we finally got on and took off, it was fine. I was supposed to have a connection in Chicago to Los Angeles, and the time for so late I was rebooked to arrive in LA 3 hours late. The departure time to Chicago later became early enough to have taken my original connection and arrive earlier but that wasn't an option.

It was one and half hour late... Not sure if any other experience matters.

Delayed flight. Nicest crew member was a SW pilot flying seated next to me who kindly move to seat the final passenger. Flight extra delayed. My cup of refreshment of ginger ale was so packed with ice it was literally 2 sips.

For my birthday trip this was my second time ever flying, this trip was the best.

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Everything was good until we were boarding our connection flight in Atlanta, we were told to gate check our carry-on, but when we got inside the plane, there was plenty of room in the overhead.

Did not know my son and I had different seating arrangements. He was fine, but it was disappointing.

Flight was canceled, and no effort was made to help with rebooking, no hotel vouchers, no car transportation and minimal food voucher and most places for food were closed by the time the voucher was given. Waited for 3 hours for bags. Simply the worst travel experience I have ever had

Food was surprisingly good but the WiFi was not great

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

The flight got delayed 2.5 hrs due to a maintenance issue that cause a domino effect. American should have spare planes for when something like this happens.

Delayed flight, so I switched fights to SFO to Phoenix , Phoenix to DSM. Excellent service through American Airlines

Everything you need to know for your flight from Des Moines to Myrtle Beach

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