DSM - MYR

$219 Find Cheap Flights from Des Moines to Myrtle Beach - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$370
Typical prices: $368-$460
American Airlines
Mon 12/3Thu 12/6
DSM - MYR • 1 stop
Cheapest one-way
$219
Typical prices: $193-$450
American Airlines
Sun 3/4
DSM - MYR • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Myrtle Beach. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 26% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Atlanta Hartsfield-Jackson (ATL)
Cheapest • Avg $414 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 4h 42m (one-way)
Insights
Insights
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We hope you love your trip to Myrtle Beach!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Myrtle Beach (DSM-MYR)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Myrtle Beach

Thu, Dec 3 - Sun, Dec 6
American Airlines Logo
11:38 am - 7:54 pmDSM  Des Moines-MYR Myrtle Beach Intl
7h 16m1 stop Charlotte Douglas
American Airlines Logo
8:34 pm - 12:02 amMYR  Myrtle Beach Intl-DSM Des Moines
4h 28m1 stop Charlotte Douglas
$379American Airlines
Wed, Mar 3 - Wed, Mar 10
Delta Logo
5:15 pm - 11:35 pmDSM  Des Moines-MYR Myrtle Beach Intl
5h 20m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 10:18 amMYR  Myrtle Beach Intl-DSM Des Moines
5h 18m1 stop Atlanta Hartsfield-Jackson
$388Delta
Thu, Dec 3 - Sun, Dec 6
American Airlines Logo
11:38 am - 7:54 pmDSM  Des Moines-MYR Myrtle Beach Intl
7h 16m1 stop Charlotte Douglas
American Airlines Logo
5:08 am - 10:58 amMYR  Myrtle Beach Intl-DSM Des Moines
6h 50m1 stop Charlotte Douglas
$389American Airlines
Wed, Mar 3 - Wed, Mar 10
American Airlines Logo
6:45 am - 12:35 pmDSM  Des Moines-MYR Myrtle Beach Intl
4h 50m1 stop Charlotte Douglas
American Airlines Logo
1:05 pm - 7:04 pmMYR  Myrtle Beach Intl-DSM Des Moines
6h 59m2 stops Charlotte Douglas Chicago O'Hare Intl
$393American Airlines
Tue, Dec 1 - Sun, Dec 6
Delta Logo
2:58 pm - 10:47 pmDSM  Des Moines-MYR Myrtle Beach Intl
6h 49m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:57 pm - 10:38 pmMYR  Myrtle Beach Intl-DSM Des Moines
4h 41m1 stop Atlanta Hartsfield-Jackson
$437Delta
Wed, Mar 31 - Sun, Apr 4
Delta Logo
5:45 am - 1:35 pmDSM  Des Moines-MYR Myrtle Beach Intl
6h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 10:18 amMYR  Myrtle Beach Intl-DSM Des Moines
5h 18m1 stop Atlanta Hartsfield-Jackson
$437Delta
Wed, Mar 31 - Sun, Apr 4
Southwest Logo
5:20 am - 12:35 pmDSM  Des Moines-MYR Myrtle Beach Intl
6h 15m2 stops Chicago Midway Nashville Intl
Southwest Logo
10:40 am - 10:20 pmMYR  Myrtle Beach Intl-DSM Des Moines
12h 40m2 stops Nashville Intl Denver Intl
$483Southwest
Tue, Nov 10 - Sat, Nov 14
United Airlines Logo
8:00 am - 5:11 pmDSM  Des Moines-MYR Myrtle Beach Intl
8h 11m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
11:27 am - 9:55 pmMYR  Myrtle Beach Intl-DSM Des Moines
11h 28m2 stops Newark Chicago O'Hare Intl
$548United Airlines
Thu, Mar 4 - Sun, Mar 7
Southwest Logo
7:30 am - 7:05 pmDSM  Des Moines-MYR Myrtle Beach Intl
10h 35m2 stops Nashville Intl Baltimore/Washington
Southwest Logo
10:40 am - 11:05 pmMYR  Myrtle Beach Intl-DSM Des Moines
13h 25m2 stops Nashville Intl Chicago Midway
$565Southwest
Thu, Mar 4 - Sun, Mar 7
Multiple Airlines Logo
2:34 pm - 8:03 amDSM  Des Moines-MYR Myrtle Beach Intl
16h 29m1 stop Fort Lauderdale
Multiple Airlines Logo
2:51 pm - 9:28 pmMYR  Myrtle Beach Intl-DSM Des Moines
31h 37m2 stops Atlantic City Fort Myers SW Florida Intl
$573Multiple Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Myrtle Beach flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Myrtle Beach?

Round-trip flights from Des Moines to Myrtle Beach typically range from $368 to $460. The lowest price found in the past 5 days was $370, on American Airlines.

What's the cheapest day of the week to fly from Des Moines to Myrtle Beach?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Des Moines to Myrtle Beach. It’s 7% cheaper than the average day, while Monday is the most expensive, with prices 4% higher.

What’s the cheapest month to fly from Des Moines to Myrtle Beach?

•January is the cheapest month to fly from Des Moines to Myrtle Beach at $293 round-trip.
•July ($486) and June ($430) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 65% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Des Moines to Myrtle Beach flights

Low season

December

Cheapest flight

$219
Beat the crowds with an average 72% drop in travelers.
The most popular month to fly with an average 52% increase in travelers.
One-way flight from Des Moines to Myrtle Beach

When to book flights from Des Moines to Myrtle Beach

Are your dates flexible? Find out the best times to travel from Des Moines to Myrtle Beach based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Myrtle Beach flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Myrtle Beach?

    Two cabin classes are available on flights from Des Moines to Myrtle Beach:

    • Economy Class
    • First Class

  • How long is a flight from Des Moines to Myrtle Beach?

    A nonstop flight from Des Moines to Myrtle Beach takes 00m, covering 969 miles.

  • Do I need a passport to fly from Des Moines to Myrtle Beach?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Myrtle Beach flight?

    Round-trip flights from Des Moines to Myrtle Beach range from $368 to $460, with an average of $397 over the past 12 months. Anything below $368 counts as a good deal.

  • Have flight prices from Des Moines to Myrtle Beach changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $379 to $2,398. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Des Moines to Myrtle Beach looking right now?

    One-way fares from Des Moines to Myrtle Beach are currently lower than usual. Average one-way flight prices are about $244, which is 33% below the typical average for this route.

  • What car rental options are available at Myrtle Beach Intl Airport (MYR)?

    Myrtle Beach Intl Airport (MYR) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include:

    • Budget
    • Alamo
    • Dollar
    • Thrifty
    • Hertz

  • Which airports can I use when flying from Des Moines to Myrtle Beach?

    Flights from Des Moines to Myrtle Beach usually depart from Des Moines (DSM) and arrive at Myrtle Beach Intl (MYR).

  • Which airports do connecting flights from Des Moines to Myrtle Beach pass through?

    One-stop flights from Des Moines to Myrtle Beach most commonly connect through:

    • Charlotte Douglas (CLT) - 52% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 21% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 15% of one-stop connections
    • Chicago Midway (MDW) - 8% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Myrtle Beach?

    Yes. Flexible dates can save you up to 12% on flights from Des Moines to Myrtle Beach. Friday is the cheapest departure day at $370 round-trip on average, while Monday is the most expensive at $416, a difference of $46.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to Myrtle Beach?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 42m, compared with 4h 55m via Chicago Midway (MDW) and 5h 01m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Des Moines and Myrtle Beach?

    Myrtle Beach is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Des Moines to Myrtle Beach flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Monday. On this route, Friday flights average $370, about $46 less than Monday fares (11% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Myrtle Beach trip for January. Fares historically average $293 round-trip in that month - typically $193 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Myrtle Beach Intl Airport.

    • Polynesian Beach & Golf Resort
    • Tropical Seas Hotel
    • Holiday Inn Club Vacations Myrtle Beach Oceanfront

More options for your flight from Des Moines to Myrtle Beach

Complete your trip to Myrtle Beach with a hotel stay or car rental

Car rentals in Myrtle Beach
Hotels in Myrtle Beach
Vacations in Myrtle Beach