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MYR - SNA

$196 Find Cheap Flights from Myrtle Beach to John Wayne (Santa Ana) - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$389
Typical prices: $436-$651
American Airlines
Sun 11/4Sun 11/11
MYR - SNA • 1 stop
Cheapest one-way
$196
Typical prices: $256-$553
American Airlines
Tue 10/30
MYR - SNA • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Santa Ana. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
April
Cheapest • 21% price drop
October
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Charlotte Douglas (CLT)
Cheapest • Avg $795 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 8h (one-way)
Insights
Insights
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We hope you love your trip to Santa Ana!

Cheap Flights from Myrtle Beach to Santa Ana (MYR-SNA)

 

Cheap flights from Myrtle Beach to Santa Ana with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Wed, Nov 4 - Wed, Nov 11
American Airlines Logo
7:20 am - 12:35 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
8h 15m1 stop Dallas/Fort Worth
American Airlines Logo
6:45 am - 10:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
12h 44m2 stops Phoenix Sky Harbor Intl Charlotte Douglas
$389American Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
11:27 am - 5:25 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
8h 58m1 stop Newark
United Airlines Logo
9:10 pm - 10:21 amSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
10h 11m1 stop Newark
$435United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
11:27 am - 5:25 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
8h 58m1 stop Newark
United Airlines Logo
8:00 pm - 10:21 amSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
11h 21m2 stops San Francisco Newark
$440United Airlines
Sun, Dec 6 - Thu, Dec 10
American Airlines Logo
4:21 pm - 10:22 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
9h 01m1 stop Charlotte Douglas
American Airlines Logo
7:15 am - 7:54 pmSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
9h 39m1 stop Charlotte Douglas
$450American Airlines
Sun, Dec 6 - Thu, Dec 10
American Airlines Logo
7:20 am - 2:04 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
9h 44m1 stop Dallas/Fort Worth
American Airlines Logo
12:10 pm - 10:43 pmSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
7h 33m1 stop Dallas/Fort Worth
$462American Airlines
Sun, Dec 6 - Thu, Dec 10
American Airlines Logo
4:21 pm - 10:22 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
9h 01m1 stop Charlotte Douglas
American Airlines Logo
12:10 pm - 10:43 pmSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
7h 33m1 stop Dallas/Fort Worth
$463American Airlines
Wed, Nov 4 - Wed, Nov 11
American Airlines Logo
8:07 am - 3:42 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
10h 35m2 stops Charlotte Douglas Phoenix Sky Harbor Intl
American Airlines Logo
6:45 am - 10:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
12h 44m2 stops Phoenix Sky Harbor Intl Charlotte Douglas
$473American Airlines
Sun, Dec 6 - Thu, Dec 10
American Airlines Logo
4:21 pm - 10:22 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
9h 01m1 stop Charlotte Douglas
American Airlines Logo
7:15 am - 7:54 pmSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
9h 39m1 stop Charlotte Douglas
$477American Airlines
Tue, Apr 6 - Fri, Apr 9
United Airlines Logo
3:20 pm - 10:00 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
9h 40m1 stop Chicago O'Hare Intl
United Airlines Logo
7:50 pm - 10:37 amSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
11h 47m2 stops San Francisco Chicago O'Hare Intl
$482United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
11:27 am - 9:19 pmMYR  Myrtle Beach Intl-SNA Santa Ana J. Wayne/Orange Cnty
12h 52m2 stops Newark Denver Intl
United Airlines Logo
6:30 pm - 10:21 amSNA  Santa Ana J. Wayne/Orange Cnty-MYR Myrtle Beach Intl
12h 51m2 stops Denver Intl Newark
$487United Airlines

Price, demand and travel trends for Myrtle Beach to Santa Ana flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Myrtle Beach to Santa Ana?

Round-trip flights from Myrtle Beach to Santa Ana typically range from $436 to $651. The lowest price found in the past 5 days was $389, on American Airlines.

What's the cheapest day of the week to fly from Myrtle Beach to Santa Ana?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Myrtle Beach to Santa Ana. It’s 21% cheaper than the average day, while Friday is the most expensive, with prices 57% higher.

Find deals

Key details for Myrtle Beach to Santa Ana flights

Low season

March

Cheapest flight

$196
One-way flight from Myrtle Beach to Santa Ana

When to book flights from Myrtle Beach to Santa Ana

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Myrtle Beach to Santa Ana flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Myrtle Beach to Santa Ana?

    Only Economy Class is available on flights from Myrtle Beach to Santa Ana.

  • How long is a flight from Myrtle Beach to Santa Ana?

    A nonstop flight from Myrtle Beach to Santa Ana takes 00m, covering 2,224 miles.

  • Do I need a passport to fly from Myrtle Beach to Santa Ana?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Myrtle Beach to Santa Ana flight?

    Round-trip flights from Myrtle Beach to Santa Ana range from $436 to $651, with an average of $525 over the past 12 months. Anything below $436 counts as a good deal.

  • Have flight prices from Myrtle Beach to Santa Ana changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $389 to $1,237. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Myrtle Beach to Santa Ana looking right now?

    One-way fares from Myrtle Beach to Santa Ana are currently lower than usual. Average one-way flight prices are about $235, which is 46% below the typical average for this route.

  • What car rental options are available at Santa Ana J. Wayne/Orange Cnty Airport (SNA)?

    Santa Ana J. Wayne/Orange Cnty Airport (SNA) hosts 5 major car rental companies, with daily rates starting from around $20 for economy cars. Top options include:

    • Dollar
    • Thrifty
    • Hertz
    • Budget
    • Alamo

  • Which airports can I use when flying from Myrtle Beach to Santa Ana?

    Flights from Myrtle Beach to Santa Ana usually depart from Myrtle Beach Intl (MYR) and arrive at Santa Ana J. Wayne/Orange Cnty (SNA).

  • Which airports do connecting flights from Myrtle Beach to Santa Ana pass through?

    One-stop flights from Myrtle Beach to Santa Ana most commonly connect through:

    • Charlotte Douglas (CLT) - 50% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 31% of one-stop connections
    • Dallas/Fort Worth (DFW) - 19% of one-stop connections

  • Can I save money by using flexible dates for flights from Myrtle Beach to Santa Ana?

    Yes. Flexible dates can save you up to 50% on flights from Myrtle Beach to Santa Ana. Saturday is the cheapest departure day at $415 round-trip on average, while Friday is the most expensive at $826, a difference of $411.

    Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from Myrtle Beach to Santa Ana?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 8h, compared with 8h 19m via Charlotte Douglas (CLT) and 10h 46m via Dallas/Fort Worth (DFW).

  • What is the time difference between Myrtle Beach and Santa Ana?

    Santa Ana is 3 hours behind Myrtle Beach (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santa Ana?

    Some of the most popular sights in Santa Ana are Embassy Suites by Hilton Santa Ana Orange County Airport, Santa Ana Zoo and Old Orange County Courthouse. These are among the most viewed places in Santa Ana on KAYAK.

Your guide to booking Myrtle Beach to Santa Ana flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Saturday departure and avoid flying on Friday. On this route, Saturday flights average $415, about $411 less than Friday fares (50% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Myrtle Beach to Santa Ana trip for April. Fares historically average $415 round-trip in that month - typically $562 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Ana J. Wayne/Orange Cnty Airport.

    • Courtyard by Marriott Santa Ana Orange County
    • voco Orange County - Airport by IHG
    • Hotel Zessa Orange County Airport, a DoubleTree by Hilton

More options for your flight from Myrtle Beach to Santa Ana

Complete your trip to Santa Ana with a hotel stay or car rental

Car rentals in Santa Ana
Hotels in Santa Ana
Vacations in Santa Ana