MYR - SNA

$158 Find Cheap Flights from Myrtle Beach to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Santa Ana departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santa Ana, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Myrtle Beach to Santa Ana (MYR-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Santa Ana

Sun, Jun 29 - Tue, Jul 1
 Logo
12:09 pm - 9:50 pmMYR-SNA
36h 41m2 stops
 Logo
5:22 pm - 10:33 amSNA-MYR
14h 11m2 stops
Sun, Jun 29 - Tue, Jul 1
 Logo
12:09 pm - 2:09 pmMYR-SNA
29h 00m2 stops
 Logo
5:22 pm - 9:40 pmSNA-MYR
25h 18m3 stops
Sat, Sep 20 - Wed, Sep 24
American Airlines Logo
7:00 am - 1:53 pmMYR-SNA
9h 53m1 stop
American Airlines Logo
10:28 am - 11:05 pmSNA-MYR
9h 37m2 stops
$317American Airlines
Find Deal
Sat, Sep 20 - Wed, Sep 24
American Airlines Logo
10:24 am - 6:03 pmMYR-SNA
10h 39m2 stops
American Airlines Logo
10:28 am - 11:05 pmSNA-MYR
9h 37m2 stops
$322American Airlines
Find Deal
Sun, Jun 29 - Tue, Jul 1
Spirit Airlines Logo
8:14 pm - 7:16 amMYR-SNA
38h 02m3 stops
Spirit Airlines Logo
5:22 pm - 9:40 pmSNA-MYR
25h 18m3 stops
$339Spirit Airlines
Find Deal
Tue, Jul 29 - Tue, Aug 12
Delta Logo
6:00 am - 4:10 pmMYR-SNA
13h 10m2 stops
Delta Logo
2:00 pm - 11:49 pmSNA-MYR
6h 49m1 stop
$348Delta
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Tue, Jul 29 - Tue, Aug 12
Delta Logo
6:00 am - 4:10 pmMYR-SNA
13h 10m2 stops
Delta Logo
4:55 pm - 10:11 amSNA-MYR
14h 16m2 stops
$353Delta
Find Deal
Fri, Jun 27 - Mon, Jun 30
Spirit Airlines Logo
8:24 pm - 7:16 amMYR-SNA
13h 52m2 stops
Spirit Airlines Logo
5:22 pm - 10:33 amSNA-MYR
14h 11m2 stops
$396Spirit Airlines
Find Deal
Fri, Aug 15 - Sat, Aug 30
United Airlines Logo
4:50 pm - 10:17 pmMYR-SNA
8h 27m1 stop
United Airlines Logo
6:45 am - 2:42 pmSNA-MYR
28h 57m1 stop
$546United Airlines
Find Deal
Fri, Aug 15 - Sat, Aug 30
United Airlines Logo
4:50 pm - 10:17 pmMYR-SNA
8h 27m1 stop
United Airlines Logo
7:00 pm - 2:42 pmSNA-MYR
16h 42m2 stops
$551United Airlines
Find Deal
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KAYAK's insights & trends for Myrtle Beach to Santa Ana flights

Get data-powered insights and trends into flights from Myrtle Beach to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to John Wayne (Santa Ana)?

The average price of all round-trip flights from Myrtle Beach to Santa Ana clicked on KAYAK for each day over the last 12 months.

For Myrtle Beach to John Wayne (Santa Ana), Saturday is the cheapest day to fly on average and Monday is the most expensive. Flying from John Wayne (Santa Ana) back to Myrtle Beach, the best deals are generally found on Tuesday, with Saturday being the most expensive.

Good to know

Low seasonOctober
High seasonOctober
Cheapest flight$158
Best time to beat the crowds with an average 32% drop in price.
Most popular time to fly and prices are also 32% lower on average.
Flight from Myrtle Beach to John Wayne (Santa Ana)

When to book flights from Myrtle Beach to Santa Ana

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to John Wayne (Santa Ana)

  • What is the cheapest flight from Myrtle Beach to Santa Ana?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Santa Ana was $158 for a one-way ticket and $253 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and John Wayne (Santa Ana)?

    A passport is not required to fly from Myrtle Beach to John Wayne (Santa Ana).

  • Which airports will I be using when flying from Myrtle Beach to John Wayne (Santa Ana)?

    On your way to John Wayne (Santa Ana), you’ll fly out from Myrtle Beach Intl. You’ll be landing at Santa Ana J. Wayne/Orange Cnty.

  • Which aircraft models fly most regularly from Myrtle Beach to John Wayne (Santa Ana)?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to John Wayne (Santa Ana)?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Myrtle Beach and John Wayne (Santa Ana), with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Santa Ana, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Santa Ana are Delta and American Airlines. With an average price for the route of $646 and an overall rating of 8.0, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $502 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airlines flying from Myrtle Beach to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7946 reviews
7.9Entertainment
8.5Crew
8.2Boarding
7.3Food
7.9Comfort
Airline reviews

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

2.0 MediocreAnonymous, Jun 2025BOS - LAX
Read more Delta reviews

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Seats are much much more comfortable than United, which is what I usually fly

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Plane was pretty clean, staff was friendly and helpful, flight left about on time arrived early. Took a long time to board and get off the plane - carry on items didn't have enough room so people had to move all around to find places.

The service and food needs to improve to catch up with other international flights

Would have been good to have a meal since it was a 5.5 hour flight

Everything you need to know for your flight from Myrtle Beach to Santa Ana

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