$193 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$533
Bogotá
Bogotá1 stop$344
Santiago
Santiago3 stops$914
Cartagena
Cartagena1 stop$370
Quito
Quito2 stops$677
Guayaquil
Guayaquil2 stops$829
Lima
Lima1 stop$533
Bogotá
Bogotá1 stop$344
Santiago
Santiago3 stops$914
Cartagena
Cartagena1 stop$370
Quito
Quito2 stops$677
Guayaquil
Guayaquil2 stops$829

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Wed, Apr 1 - Tue, Apr 14
Multiple Airlines Logo
6:28 pm - 1:11 pm
MYR
-
BOG
19h 43m
1 stop
Multiple Airlines Logo
2:10 pm - 3:43 pm
BOG
-
MYR
24h 33m
1 stop
$344Multiple Airlines
Wed, Apr 1 - Mon, Apr 13
Spirit Airlines Logo
6:28 pm - 1:11 pm
MYR
-
BOG
19h 43m
1 stop
Spirit Airlines Logo
2:10 pm - 5:33 pm
BOG
-
MYR
26h 23m
1 stop
$346Spirit Airlines
Wed, May 13 - Sat, May 23
American Airlines Logo
6:00 am - 8:15 pm
MYR
-
MDE
15h 15m
2 stops
American Airlines Logo
1:53 pm - 12:28 pm
MDE
-
MYR
21h 35m
2 stops
$547American Airlines
Wed, May 13 - Sun, May 24
American Airlines Logo
5:00 am - 8:15 pm
MYR
-
MDE
16h 15m
2 stops
American Airlines Logo
11:59 pm - 5:26 pm
MDE
-
MYR
16h 27m
2 stops
$567American Airlines
Wed, Apr 22 - Tue, Apr 28
LATAM Airlines Logo
1:43 pm - 5:00 am
MYR
-
LIM
16h 17m
2 stops
LATAM Airlines Logo
12:10 am - 6:06 pm
LIM
-
MYR
16h 56m
2 stops
$640LATAM Airlines
Mon, Jun 22 - Mon, Jul 6
LATAM Airlines Logo
1:05 pm - 5:00 am
MYR
-
LIM
16h 55m
1 stop
LATAM Airlines Logo
12:10 am - 7:04 pm
LIM
-
MYR
17h 54m
2 stops
$665LATAM Airlines
Sun, Jun 21 - Mon, Jul 6
Delta Logo
3:40 pm - 5:00 am
MYR
-
LIM
14h 20m
2 stops
Delta Logo
12:15 am - 11:38 pm
LIM
-
MYR
22h 23m
2 stops
$670Delta
Wed, May 13 - Tue, May 26
Delta Logo
4:07 pm - 5:00 am
MYR
-
LIM
13h 53m
1 stop
Delta Logo
12:05 pm - 11:57 pm
LIM
-
MYR
10h 52m
1 stop
$685Delta
Mon, Mar 30 - Thu, Apr 2
United Airlines Logo
3:15 pm - 9:10 pm
MYR
-
MDE
30h 55m
2 stops
United Airlines Logo
9:45 am - 10:18 am
MDE
-
MYR
23h 33m
2 stops
$719United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
11:29 am - 11:36 pm
MYR
-
CLO
13h 07m
2 stops
United Airlines Logo
8:46 am - 10:18 am
CLO
-
MYR
24h 32m
2 stops
$873United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($346) and Delta ($589).

Good to know

Low seasonAugust
Cheapest flight$193
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 51% increase in price.
Flight from Myrtle Beach to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8285 reviews
7.2Food
7.8Entertainment
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

2.0 MediocreIsabella, Mar 2026
SLC - AUS
Read more Delta reviews

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

The flight was flying with 30% capacity. The flight my seat from preferred seating to back of the seat. Even though i can understand that this was to balance the flight weight. The flight attendance decided to do the serving near my seat and in the middle , their noices woke me up from sleep , when i realized that the service has ended and when they were going back asked for a coffee, for which they answered they have completed teh service in my location. That really upset me as they woke me up and also rejected the coffee i asked. I ended up landing with a headache, thanks to the crew that screwed up my travel

Delayed. Hot. Passenger next to me was so large I couldn’t move.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

The boarding process doesn't make sense since some people that will sit behind your rows are boarded before you and then they take up the luggage space above your head. I then have to wait for people to get off the plane before I can go back to get my luggage.

For a change, friendly staff at check-in and in flight.

Delayed both in takeoff and landing, trash plane no amenities, I've said it before but I'll never fly Spirit again.

My flight was delayed by over an hour and the turbulance was horrible.

Everything is an additional fee. No one said anything when I checking in and got my boarding pass about my small carry on suitcase. Charged me $100 at the gate for that little bag that I still had to take with me. Delays for both flights for no reason and then when I asked everyone said something different. Never flying spirit again. If it was just one thing maybe. This was a show from the minute I got to the airport.

I had a great experience from booking to boarding to landing. This was the best experience from all the flights I’ve had with Spirit so far! The price and times were affordable and perfect. I will fly with them again soon!

Terrible. The flight was randomly delayed in Chicago causing us to miss our connection and they offered us a flight the next day at 6 am and it would have taken till 345 to get to Pensacola. They didn’t cover any fees. Our bags also supposedly were on the flight to Pensacola and we tried to get them yesterday after driving 6 hours and nobody was available. Worst company ever and will never use them again. Had to pay for a rental. Spirit is claiming in climate weather for the delay but there wasn’t any weather issuesz it’s a bunch of bullshit and I am not happy

First off, I had a conversation with a flight attendant that was working this flight. I overheard her telling another flight attendant while we were in line for Chic-Fil-A that the flight was not going to land until 12:47 pm. I found this odd since the flight was to take off at 1:03. I commented to the flight attendant that was going to mess up the on-time take-off She said. if you fly alot you will notice that it's a good thing if the flight even arrives at all. I said that was a low bar. I think that flight attendants represent their airlines whether on board or in the airport ordering food. I was surprised to hear such negativity. However, I have noticed that Spirit flight attendants are usually in a sour mood.. Eventually the flight arrived and I boarded and the flight took off an hour late. There was no direction about the on-board wi-fi. Nor was there any info in the seat back pocket. I don't know if there was wi-fi or not, There were no complimentary snacks or drinks for my row 36 as there was turbulence and the captain asked the flight attendants to stop serving just as they were close to my row. When the turbulence stopped, they did have time to serve us but they did not. Upon arriving, the flight attendant asked anyone not having to catch a flight to Ft. Laudersle which was a tight connection to sit down and let those people pass. I complied but I could not help thinking that if Spirit would have took off on time that they would not have to inconvenience their passengers. All in all, I think Spirit is a mediocre airline at best. There are so many things they could do to improve. Yet, since I only fly Spirit infrequently preferring Southwest and Delta, I like to see if they are improving and sadly no, they are not. One good thing - nice modern seats and interiors.

I have to wait for the flight for 3 hours. The gate was switching for 5 times. Made feel frustrated. Delays took all my sleep. I went to work without any sleep.

Staff was good! Didn't like how slow the luggage return was

Checking in at desk in Chicago was horrible. Person was not friendly never smiled and said my flight was not paid for so I had to give another credit card. Then it ended up that I was charged twice. Then after arriving at my destination had to wait on the phone a long time to speak to a person to fix the double charge! Thank goodness the flight was perfect.

Everything you need to know for your flight to South America

Information on your arrival and departure airports