$280 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$714
Bogotá
Bogotá1 stop$440
Cartagena
Cartagena1 stop$507
Quito
Quito2 stops$704
Guayaquil
Guayaquil2 stops$744
Lima
Lima2 stops$714
Bogotá
Bogotá1 stop$440
Cartagena
Cartagena1 stop$507
Quito
Quito2 stops$704
Guayaquil
Guayaquil2 stops$744

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Thu, Oct 2 - Thu, Oct 30
 Logo
5:20 pm - 7:25 pmMYR-BOG
27h 05m1 stop
 Logo
8:40 am - 6:58 pmBOG-MYR
9h 18m1 stop
Fri, Dec 5 - Mon, Dec 15
Spirit Airlines Logo
8:30 pm - 11:03 amMYR-MDE
14h 33m1 stop
Spirit Airlines Logo
6:59 pm - 10:41 amMDE-MYR
15h 42m1 stop
$450Spirit Airlines
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Fri, Dec 5 - Mon, Dec 15
American Airlines Logo
12:41 pm - 11:39 pmMYR-MDE
10h 58m2 stops
American Airlines Logo
7:00 am - 8:50 pmMDE-MYR
13h 50m2 stops
$541American Airlines
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Tue, Mar 10 - Fri, Mar 13
Delta Logo
2:15 pm - 12:05 pmMYR-BOG
22h 50m2 stops
Delta Logo
2:55 pm - 11:35 pmBOG-MYR
7h 40m1 stop
$543Delta
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Tue, Mar 10 - Fri, Mar 13
Delta Logo
6:00 am - 8:10 pmMYR-BOG
15h 10m2 stops
Delta Logo
10:55 am - 10:08 amBOG-MYR
22h 13m2 stops
$547Delta
Find Deal
Tue, Mar 10 - Thu, Mar 12
LATAM Airlines Logo
10:55 am - 6:26 amMYR-CLO
20h 31m2 stops
LATAM Airlines Logo
7:17 am - 11:35 pmCLO-MYR
15h 18m2 stops
$647LATAM Airlines
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Sat, Feb 21 - Mon, Mar 2
American Airlines Logo
5:33 am - 8:55 pmMYR-MDE
15h 22m2 stops
American Airlines Logo
6:50 am - 9:14 pmMDE-MYR
14h 24m2 stops
$704American Airlines
Find Deal
Fri, Nov 21 - Sat, Nov 29
LATAM Airlines Logo
2:41 pm - 5:00 amMYR-LIM
14h 19m2 stops
LATAM Airlines Logo
8:00 am - 11:44 pmLIM-MYR
15h 44m2 stops
$714LATAM Airlines
Find Deal
Fri, Dec 12 - Fri, Jan 2
United Airlines Logo
1:16 pm - 11:05 pmMYR-BOG
9h 49m1 stop
United Airlines Logo
12:40 am - 12:01 pmBOG-MYR
11h 21m1 stop
$1,695United Airlines
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Fri, Dec 12 - Fri, Jan 2
United Airlines Logo
1:16 pm - 11:05 pmMYR-BOG
9h 49m1 stop
United Airlines Logo
12:40 am - 12:01 pmBOG-MYR
11h 21m1 stop
$1,696United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($450) and American Airlines ($541).

Good to know

Low seasonAugust
Cheapest flight$280
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Myrtle Beach to Lima

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $844 on average. Morning departures are around 1% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $853.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1847 reviews
7.0Entertainment
7.4Comfort
7.6Boarding
8.0Crew
6.7Food
Airline reviews

The flight was late. Please do not delay next time.

6.0 GoodAnonymous, Aug 2025AUS - ATL
Read more LATAM Airlines reviews

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Everything was fine. I'm average height and I pack light. I'm ready for my Spirit flight.

Changing the flight time to 6:15 am on the return flight is extremely inconvenient. The flight was okay. It was on time. The crew was friendly. The seats were uncomfortable. All the upsells are annoying, and I would prefer paying a single higher fee and not have to purchase so much extra.

Spirit Airlines was ok but TRAVELHELPDESK, the 3rd party travel agent IS A JOKE! VERY RUDE CUSTOMER AGENTS ont he phone. NO HELP AT ALL. But the airlines was ok.

No Tumberlence smooth flight. Try to change the menu on Snacks.

Cancelled my flight last minute and did not help me rebook. It was a horrible experience.

No frills - because you get what you pay for. The crew was amazing!! I had plenty of room to spread out because the flight was half full. Which made it easy to sleep.

The terminal crew is so rude cabin crew is extremely rude flight is very good

Spirit is low fare air line. Food also cost you. No free food.

The flight was delayed twice with minimal explanation. The terminal and airplane were filthy. The food voucher didn’t even cover a tiny pizza from a kiosk in the terminal. All in all, a pretty miserable experience for a flight to attend a funeral

I will use spirit more New clean aircraft Excellent crew ! Quick boarding process !

Everything you need to know for your flight to South America

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