$180 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$665
Bogotá
Bogotá2 stops$616
Santiago
Santiago3 stops$975
Cartagena
Cartagena1 stop$514
Quito
Quito2 stops$724
Guayaquil
Guayaquil2 stops$518
Lima
Lima2 stops$665
Bogotá
Bogotá2 stops$616
Santiago
Santiago3 stops$975
Cartagena
Cartagena1 stop$514
Quito
Quito2 stops$724
Guayaquil
Guayaquil2 stops$518

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Thu, Jul 16 - Thu, Jul 23
Multiple Airlines Logo
11:59 am - 12:07 pm
MYR
-
CTG
25h 08m
1 stop
Multiple Airlines Logo
1:12 pm - 9:50 am
CTG
-
MYR
19h 38m
1 stop
$514Multiple Airlines
Sun, May 10 - Sat, May 23
Multiple Airlines Logo
6:00 am - 8:55 am
MYR
-
GYE
27h 55m
2 stops
Multiple Airlines Logo
3:30 am - 8:36 pm
GYE
-
MYR
16h 06m
2 stops
$518Multiple Airlines
Sat, Jul 18 - Fri, Jul 31
Spirit Airlines Logo
3:43 pm - 1:25 pm
MYR
-
MDE
22h 42m
1 stop
Spirit Airlines Logo
2:26 pm - 8:11 pm
MDE
-
MYR
28h 45m
1 stop
$544Spirit Airlines
Fri, Jul 17 - Fri, Jul 24
American Airlines Logo
6:45 pm - 12:35 pm
MYR
-
CTG
18h 50m
2 stops
American Airlines Logo
3:17 pm - 12:51 pm
CTG
-
MYR
20h 34m
2 stops
$606American Airlines
Sat, Jul 18 - Fri, Jul 31
American Airlines Logo
8:12 am - 8:16 pm
MYR
-
MDE
13h 04m
2 stops
American Airlines Logo
6:00 am - 10:20 pm
MDE
-
MYR
15h 20m
2 stops
$608American Airlines
Mon, May 25 - Mon, Jun 1
Delta Logo
6:00 am - 1:40 pm
MYR
-
BOG
8h 40m
1 stop
Delta Logo
5:00 am - 11:58 pm
BOG
-
MYR
17h 58m
2 stops
$633Delta
Mon, May 25 - Mon, Jun 1
Delta Logo
6:00 am - 1:40 pm
MYR
-
BOG
8h 40m
1 stop
Delta Logo
2:55 pm - 10:39 am
BOG
-
MYR
18h 44m
1 stop
$639Delta
Thu, Jul 16 - Thu, Jul 23
Spirit Airlines Logo
9:06 pm - 12:07 pm
MYR
-
CTG
16h 01m
2 stops
Spirit Airlines Logo
1:12 pm - 11:37 am
CTG
-
MYR
21h 25m
2 stops
$655Spirit Airlines
Wed, Aug 26 - Fri, Sep 25
LATAM Airlines Logo
6:45 pm - 5:00 am
MYR
-
LIM
11h 15m
1 stop
LATAM Airlines Logo
12:05 am - 6:00 pm
LIM
-
MYR
16h 55m
1 stop
$715LATAM Airlines
Thu, Aug 27 - Sat, Sep 26
LATAM Airlines Logo
6:00 am - 8:20 pm
MYR
-
LIM
15h 20m
2 stops
LATAM Airlines Logo
12:05 am - 6:00 pm
LIM
-
MYR
16h 55m
1 stop
$721LATAM Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to South America is January, when tickets cost $0 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $682 and $676 respectively.

Good to know

Low seasonAugust
Cheapest flight$180
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 48% increase in price.
Flight from Myrtle Beach to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8466 reviews
7.2Food
8.5Crew
7.8Entertainment
8.1Boarding
7.9Comfort
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Everything you need to know for your flight to South America

Information on your arrival and departure airports