$153 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$599
Bogotá
Bogotá1 stop$436
Santiago
Santiago2 stops$734
Quito
Quito2 stops$569
Lima
Lima2 stops$599
Bogotá
Bogotá1 stop$436
Santiago
Santiago2 stops$734
Quito
Quito2 stops$569

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Sat, Sep 20 - Sun, Sep 28
Spirit Airlines Logo
4:23 pm - 1:10 pmMYR-BOG
21h 47m1 stop
Spirit Airlines Logo
2:05 pm - 8:06 pmBOG-MYR
29h 01m1 stop
$436Spirit Airlines
Find Deal
Sat, Sep 20 - Sun, Sep 28
Spirit Airlines Logo
4:23 pm - 1:10 pmMYR-BOG
21h 47m1 stop
Spirit Airlines Logo
2:05 pm - 11:57 amBOG-MYR
20h 52m2 stops
$451Spirit Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
American Airlines Logo
5:00 am - 11:39 pmMYR-MDE
18h 39m2 stops
American Airlines Logo
1:30 am - 3:28 pmMDE-MYR
13h 58m2 stops
$555American Airlines
Find Deal
Mon, Dec 1 - Wed, Dec 10
American Airlines Logo
5:03 am - 11:04 pmMYR-UIO
18h 01m2 stops
American Airlines Logo
8:20 am - 10:37 pmUIO-MYR
14h 17m2 stops
$569American Airlines
Find Deal
Mon, Dec 1 - Wed, Dec 10
Delta Logo
10:33 am - 8:00 pmMYR-UIO
9h 27m1 stop
Delta Logo
11:45 pm - 5:55 pmUIO-MYR
18h 10m1 stop
$574Delta
Find Deal
Thu, Dec 11 - Tue, Dec 16
 Logo
9:59 am - 9:15 amMYR-MDE
23h 16m2 stops
 Logo
6:59 pm - 10:41 amMDE-MYR
15h 42m1 stop
Mon, Dec 1 - Wed, Dec 10
Delta Logo
10:33 am - 8:00 pmMYR-UIO
9h 27m1 stop
Delta Logo
7:00 pm - 10:08 amUIO-MYR
15h 08m2 stops
$579Delta
Find Deal
Wed, Sep 24 - Tue, Oct 7
LATAM Airlines Logo
6:55 pm - 6:25 amMYR-LIM
12h 30m2 stops
LATAM Airlines Logo
12:05 am - 6:03 pmLIM-MYR
16h 58m2 stops
$619LATAM Airlines
Find Deal
Wed, Nov 12 - Sat, Nov 29
LATAM Airlines Logo
10:33 am - 9:20 pmMYR-LIM
10h 47m1 stop
LATAM Airlines Logo
11:40 pm - 1:56 pmLIM-MYR
38h 16m2 stops
$698LATAM Airlines
Find Deal
Wed, Sep 24 - Wed, Oct 8
 Logo
7:36 pm - 12:35 amMYR-LIM
29h 59m3 stops
 Logo
8:25 pm - 8:04 pmLIM-MYR
22h 39m2 stops
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($436) and American Airlines ($555).

Good to know

Low seasonFebruary
Cheapest flight$153
Best time to beat the crowds with an average 38% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Myrtle Beach to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $844 on average. Morning departures are around 1% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $853.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1842 reviews
7.6Boarding
7.4Comfort
8.0Crew
6.7Food
7.0Entertainment
Airline reviews

The flight was late. Please do not delay next time.

6.0 GoodAnonymous, Aug 2025AUS - ATL
Read more LATAM Airlines reviews

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Spirit is low fare air line. Food also cost you. No free food.

The flight was delayed twice with minimal explanation. The terminal and airplane were filthy. The food voucher didn’t even cover a tiny pizza from a kiosk in the terminal. All in all, a pretty miserable experience for a flight to attend a funeral

I will use spirit more New clean aircraft Excellent crew ! Quick boarding process !

Everyone was kind for the most part. I did travel with children and paid for seats and even then it was not as suitable. I tried calling their customer service prior to check in and I was told they couldn't help me because I didn't purchase my tickets with them.

Flight was late, after my first leg was cancelled altogether causing me to spend $$$ with another carrier. Seating is ridiculously tight, I can't recommend spirit if I cant depend on them to get me there and back on time.

Wow truly top notch airline Efficient nice snacks courteous staff Fast boarding !

The staff was very very rude in Las Vegas when boarding the flight. When presenting the boarding ticket. Las Vegas flight, it was hot and stuffy, it smelled really bad.

Dear All, I have harassment and accident with the flight attendant . This is my phone to talk 8168073567, please, leave phone message . Regards Emily,

The incoming plane ✈️ was delayed 5 hours en route to Raleigh. My flight was delayed for 5 hours 😢. Finally boarded and then de boarded due to an AC problem. A very tough and long night.

Flight was on time but the amount of noise from several children and the kicking of my seat the entire flight was overwhelming.

Everything you need to know for your flight to South America

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