$182 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from Myrtle Beach

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$556
Bogotá
Bogotá1 stop$493
Cartagena
Cartagena1 stop$296
Santiago
Santiago2 stops$615
Guayaquil
Guayaquil2 stops$636
Lima
Lima2 stops$556
Bogotá
Bogotá1 stop$493
Cartagena
Cartagena1 stop$296
Santiago
Santiago2 stops$615
Guayaquil
Guayaquil2 stops$636

Cheap Flights from Myrtle Beach to South America

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Myrtle Beach to South America

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Myrtle Beach to South America.
Discover the best prices for you by selecting your travel dates on KAYAK.
Spirit Airlines Logo
5:32 pm - 12:10 pmMYR-CTG
19h 38m1 stop
Spirit Airlines Logo
1:15 pm - 9:05 pmCTG-MYR
6h 50m1 stop
$296Spirit Airlines
Find Deal
Mon, Jun 2 - Thu, Jun 5
Spirit Airlines Logo
5:32 pm - 12:10 pmMYR-CTG
19h 38m1 stop
Spirit Airlines Logo
1:15 pm - 9:05 pmCTG-MYR
6h 50m1 stop
$334Spirit Airlines
Find Deal
Mon, Jun 2 - Sat, Jun 7
 Logo
5:32 pm - 6:50 pmMYR-MDE
26h 18m1 stop
 Logo
10:20 am - 9:05 pmMDE-MYR
9h 45m1 stop
Wed, Jun 4 - Tue, Jun 10
 Logo
5:32 pm - 9:25 pmMYR-CTG
28h 53m2 stops
 Logo
6:55 am - 9:05 pmCTG-MYR
13h 10m2 stops
Sun, Jun 1 - Thu, Jun 5
Delta Logo
7:59 pm - 10:55 amMYR-BOG
15h 56m2 stops
Delta Logo
7:00 am - 7:05 pmBOG-MYR
11h 05m2 stops
$529Delta
Find Deal
Sun, Jul 6 - Mon, Jul 14
United Airlines Logo
4:50 pm - 9:10 pmMYR-MDE
29h 20m2 stops
United Airlines Logo
9:45 am - 2:35 pmMDE-MYR
27h 50m2 stops
$548United Airlines
Find Deal
Tue, Jul 8 - Thu, Jul 17
Delta Logo
6:00 am - 8:10 pmMYR-BOG
15h 10m2 stops
Delta Logo
1:35 am - 12:35 pmBOG-MYR
10h 00m2 stops
$553Delta
Find Deal
Thu, Jul 10 - Sun, Jul 13
United Airlines Logo
4:50 pm - 4:42 amMYR-MDE
36h 52m2 stops
United Airlines Logo
9:45 am - 2:06 pmMDE-MYR
51h 21m2 stops
$565United Airlines
Find Deal
Tue, Jul 8 - Wed, Jul 16
LATAM Airlines Logo
1:25 pm - 8:00 amMYR-LIM
19h 35m2 stops
LATAM Airlines Logo
8:15 am - 12:05 amLIM-MYR
14h 50m2 stops
$661LATAM Airlines
Find Deal
Wed, Jun 18 - Tue, Jul 8
LATAM Airlines Logo
6:00 am - 9:40 pmMYR-LIM
16h 40m2 stops
LATAM Airlines Logo
12:00 pm - 10:15 amLIM-MYR
21h 15m1 stop
$668LATAM Airlines
Find Deal
Tue, Jun 24 - Wed, Jul 2
Useful Info

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($296) and Delta ($529).


Good to know

Cheapest flight$182
Flight from Myrtle Beach to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $844 on average. Morning departures are around 1% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $853.

Top 3 airlines serving from Myrtle Beach to South America

Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7936 reviews
7.3Food
8.2Boarding
8.5Crew
7.9Comfort
7.9Entertainment
Airline reviews

Our bag was lost so that made unnecessary chaos On our trip

6.0 GoodBarbara, Apr 2025JFK - FCO
Read more Delta reviews

Our bag was lost so that made unnecessary chaos On our trip

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

It was an overnight flight and I desperately needed coffee before we landed, but Delta does only one beverage service, and that is shortly after takeoff, not before landing at 5 am.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

No entertainment but not expected. Unless you are referring to monitor that you can use. Then Al, was fine on all flights.

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

Not having it be changed after we bought the flight tickets from a direct flight getting in at a reasonable time to a connecting flight red eye of 9 hours, so that we would lose our 35 dollars in nonrefundable insurance would've been great! Our country really does need low-cost carrier options, but this type of "service" ain't it. Fortunately, had a little better success with them flying to and from San Juan PR last month at least.

All was good expecting the seats need a bit of cushion. Besides that I can’t complain.

You get what you pay for, and the flights went smoothly. There’s no reclining chairs, no screens, And there isn’t always wifi, but the plane was clean and staff was friendly and the takeoff/landing were smooth.

The only positive is that the flight made it both ways. Getting charged for every little thing after the cost of the ticket itself is comical, considering how the plane and services are as bottom-tier as possible. The self check-in kiosks are useless. It’s nice to think that you can print your boarding pass, tag your checked bag, and then just drop it off. But no, they still make you go through the line once you finish- what’s the point of the self check-in then? Any questions for the staff seem like the biggest inconvenience and were met with condescending responses. This was my first and now last time ever flying with Spirit. After all the extra costs, subpar plane and staff, I see no value. I’d rather drive the 13 hours than give Spirit another dime.

The flight was fine however what started as a reasonable priced ticket could have become an overpriced ticket with additional charge for carry on as well as checked bag $79 per bag per person each way. Additional charge for choosing one’s seat, additional charge for beverage and snack, we were on what was described as a new plane yet there were no audio/visual on the jet. A bare bones service but not at a bare bones price. Will think twice before flying Spirit again. 😕

Flight was delayed a bit, but that was expected (and updated), so really not bad at all for the price. Could’ve used one less email asking me to upgrade my seat; otherwise no significant complaints

I love Spirit. New aircraft, great cabin service, the airfares are low cost which helps me visit my hospitalized daughter anytime I can without paying a fortune.

Flight was 2hours late they had no crew or the pilot.

I paid for streaming wifi and the connection was poor.

We had an 8 hr delay so it was not good

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