$136 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$638
Bogotá
Bogotá1 stop$445
Santiago
Santiago3 stops$978
Cartagena
Cartagena1 stop$373
Quito
Quito2 stops$662
Guayaquil
Guayaquil2 stops$728
Lima
Lima2 stops$638
Bogotá
Bogotá1 stop$445
Santiago
Santiago3 stops$978
Cartagena
Cartagena1 stop$373
Quito
Quito2 stops$662
Guayaquil
Guayaquil2 stops$728

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Thu, May 7 - Thu, May 14
Spirit Airlines Logo
6:00 am - 12:26 pm
MYR
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 8:36 pm
CTG
-
MYR
6h 05m
1 stop
$373Spirit Airlines
Thu, May 7 - Thu, May 14
Spirit Airlines Logo
6:00 am - 12:26 pm
MYR
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 8:36 pm
CTG
-
MYR
6h 05m
1 stop
$383Spirit Airlines
Wed, May 6 - Wed, May 13
Multiple Airlines Logo
3:17 pm - 1:03 pm
MYR
-
BOG
22h 46m
1 stop
Multiple Airlines Logo
10:05 pm - 2:20 pm
BOG
-
MYR
39h 15m
2 stops
$445Multiple Airlines
Wed, May 6 - Wed, May 13
Multiple Airlines Logo
10:24 am - 1:03 pm
MYR
-
BOG
27h 39m
2 stops
Multiple Airlines Logo
5:40 am - 8:36 pm
BOG
-
MYR
13h 56m
2 stops
$473Multiple Airlines
Mon, Jun 1 - Mon, Jun 15
American Airlines Logo
8:41 pm - 1:05 pm
MYR
-
BOG
17h 24m
2 stops
American Airlines Logo
2:10 pm - 11:37 am
BOG
-
MYR
20h 27m
2 stops
$574American Airlines
Mon, Jun 1 - Sun, Jun 14
United Airlines Logo
6:50 pm - 4:25 am
MYR
-
BOG
10h 35m
1 stop
United Airlines Logo
12:14 am - 2:12 pm
BOG
-
MYR
36h 58m
2 stops
$579United Airlines
Mon, Jun 1 - Mon, Jun 15
American Airlines Logo
6:33 am - 10:38 pm
MYR
-
BOG
17h 05m
1 stop
American Airlines Logo
2:10 pm - 11:37 am
BOG
-
MYR
20h 27m
2 stops
$594American Airlines
Wed, May 6 - Wed, May 13
LATAM Airlines Logo
6:00 am - 1:40 pm
MYR
-
BOG
8h 40m
1 stop
LATAM Airlines Logo
9:00 am - 7:04 pm
BOG
-
MYR
9h 04m
1 stop
$633LATAM Airlines
Thu, Sep 17 - Tue, Oct 6
LATAM Airlines Logo
6:00 am - 8:20 pm
MYR
-
LIM
15h 20m
2 stops
LATAM Airlines Logo
12:05 am - 1:35 pm
LIM
-
MYR
12h 30m
1 stop
$709LATAM Airlines
Mon, May 4 - Thu, May 7
United Airlines Logo
3:14 pm - 9:10 pm
MYR
-
MDE
30h 56m
2 stops
United Airlines Logo
9:45 am - 10:42 am
MDE
-
MYR
47h 57m
2 stops
$736United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($373) and American Airlines ($574).

Good to know

Low seasonAugust
Cheapest flight$136
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 49% increase in price.
Flight from Myrtle Beach to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1910 reviews
6.7Food
8.0Crew
7.0Entertainment
7.5Boarding
7.3Comfort
Airline reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

10.0 ExcellentYelen, Mar 2026
ATL - TPA
Read more LATAM Airlines reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The attendant at the gate was not helpful at all and she was rude when we asked why the flight was delayed.

Great just wish they always had WiFi on every flight couldn’t even purchase it

They cancelled my flight with no reason affecting my travel plans and delaying it 24 hours.

a weekend long saga that ultimately led to a canceled trip. totally unreliable.

Everything was horrible. They delayed my flight so I missed my connection flight and I lost my bags. I had to go to the same workers multiple times asking the same questions because everyone kept giving me different answers. One person closed down customer service because he wanted to go on lunch so there was like 30 people just waiting for hours because no one would relieve him.

Landing was technically perfect. What I didn't like is the pricey internet. Both flights with excellent crews. I'm 6 feet 210 pounds and could easily fit in the chair.

Paid for WiFi and the connection was basically nonexistent. Was pleasantly surprised with everything else. Staff was great. Boarding was easy. Plane was clean. Overall, a very pleasant experience

Long long delay, no AC while delayed, gate changes, just for the most uncomfortable flight of your life.

Everything was smooth sailing. Great crew, easy flight and was surprised with an upgraded seat. Thank you all!

My first time experience with Spirit Air was not good at all.The reason i did not know to cancel 24Hrs before flight depature you do charge cancellation fee. It's ridiculous policy.Actually you should provide full voucher instead of charging cancellation fee. Confirmation Code# ZNVPHG Thanks Much , Rita S

Everything you need to know for your flight to South America

Information on your arrival and departure airports