$166 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$612
Bogotá
Bogotá2 stops$480
Santiago
Santiago2 stops$925
Cartagena
Cartagena1 stop$316
Quito
Quito2 stops$682
Guayaquil
Guayaquil2 stops$913
Lima
Lima1 stop$612
Bogotá
Bogotá2 stops$480
Santiago
Santiago2 stops$925
Cartagena
Cartagena1 stop$316
Quito
Quito2 stops$682
Guayaquil
Guayaquil2 stops$913

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Fri, Apr 10 - Fri, Apr 17
Spirit Airlines Logo
6:28 pm - 12:06 pm
MYR
-
CTG
18h 38m
1 stop
Spirit Airlines Logo
1:11 pm - 11:29 pm
CTG
-
MYR
9h 18m
1 stop
$316Spirit Airlines
Fri, Apr 10 - Fri, Apr 17
Spirit Airlines Logo
6:28 pm - 12:06 pm
MYR
-
CTG
18h 38m
1 stop
Spirit Airlines Logo
1:11 pm - 11:29 pm
CTG
-
MYR
9h 18m
1 stop
$320Spirit Airlines
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
11:52 am - 1:08 pm
MYR
-
MDE
26h 16m
1 stop
Multiple Airlines Logo
6:25 am - 11:29 pm
MDE
-
MYR
16h 04m
2 stops
$431Multiple Airlines
Wed, May 13 - Sat, May 23
Multiple Airlines Logo
11:52 am - 9:25 pm
MYR
-
MDE
10h 33m
1 stop
Multiple Airlines Logo
9:45 am - 8:58 pm
MDE
-
MYR
34h 13m
2 stops
$457Multiple Airlines
Thu, May 14 - Mon, May 18
United Airlines Logo
11:57 am - 10:00 pm
MYR
-
BOG
11h 03m
1 stop
United Airlines Logo
8:30 am - 10:42 am
BOG
-
MYR
25h 12m
2 stops
$586United Airlines
Thu, May 14 - Mon, May 18
LATAM Airlines Logo
6:00 am - 1:40 pm
MYR
-
BOG
8h 40m
1 stop
LATAM Airlines Logo
2:55 pm - 11:58 pm
BOG
-
MYR
8h 03m
1 stop
$637LATAM Airlines
Wed, Sep 2 - Wed, Sep 9
Delta Logo
6:00 am - 8:20 pm
MYR
-
LIM
15h 20m
2 stops
Delta Logo
8:55 am - 10:09 am
LIM
-
MYR
24h 14m
2 stops
$665Delta
Tue, Sep 1 - Tue, Sep 8
Delta Logo
6:45 pm - 5:00 am
MYR
-
LIM
11h 15m
1 stop
Delta Logo
12:15 am - 6:00 pm
LIM
-
MYR
16h 45m
2 stops
$670Delta
Fri, Apr 10 - Mon, Apr 13
United Airlines Logo
11:57 am - 10:00 pm
MYR
-
BOG
11h 03m
1 stop
United Airlines Logo
8:30 am - 2:17 pm
BOG
-
MYR
28h 47m
2 stops
$709United Airlines
Fri, Apr 10 - Mon, Apr 13
LATAM Airlines Logo
10:23 am - 7:15 pm
MYR
-
BOG
9h 52m
1 stop
LATAM Airlines Logo
2:55 pm - 9:40 am
BOG
-
MYR
17h 45m
1 stop
$748LATAM Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($380) and United Airlines ($586).

Good to know

Low seasonAugust
Cheapest flight$166
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 51% increase in price.
Flight from Myrtle Beach to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8322 reviews
8.1Boarding
7.9Comfort
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

The cabin temperature was nice and cool. The wifi was not working.

8.0 ExcellentMatt, Mar 2026
SEA - SJC
Read more Delta reviews

The cabin temperature was nice and cool. The wifi was not working.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

As previously noted, this flight was great: departure was timely, the crew was friendly and attentive, and wifi connectivity was seamless. In particular, I appreciated that the flight attendant just told me to stow the laptop right before takeoff/landing, and trusted me to do so (which I did!).

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Entertainment is ok! Boarding and seat with zone is terrible. I paid for the seats but you didn’t give me what I paid for which is exit isles.

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was a big joke very uncomfortable I had a horrible experience and I will never fly with them again everything about the flight was bogus and I’m not happy with it at all this experience makes me not want to fly ever again

Pricing, boarding time communication, over priced baggage and overall service is lacking, seating unconfortable

Flight attendant was all so sweet and pilot got us to our destination safely and on time

They cancelled our flight. 2 hours before we were supposed to take off and offered us nothing! We got our money back and that was it. No other flight to get to our cruise no working with another airline or with us to get there. Terrible customer service, no apology.

we boarded the plane and then sat for OVER AN HOUR on it, first waiting for fuel and then the crew timed out. the flight kept getting delayed longer and longer, a 9:30pm flight is still on the ground at 1:15am.

The airplane rattled near the left wing as if several screws were loose. Then after we landed in Fort Lauderdale, we had to sit and wait on the runway for quite some time. It was very scary and TOTALLY unacceptable!

Smooth flight staff very friendly and we arrived 15 mins earlier

I was in the airport when I'll check the status of my flight and it was canceled and without any reason. The worst of the worst ...

I never had an opportunity to experience them! They cancelled my flight TWICE!!!

Return flight was canceled. Needed to reschedule with another airline the next day. Cost an an additional $84. At another airport 45 miles further away

Everything you need to know for your flight to South America

Information on your arrival and departure airports