$275 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$715
Bogotá
Bogotá1 stop$582
Santiago
Santiago2 stops$1,350
Cartagena
Cartagena2 stops$666
Quito
Quito2 stops$678
Guayaquil
Guayaquil2 stops$751
Lima
Lima2 stops$715
Bogotá
Bogotá1 stop$582
Santiago
Santiago2 stops$1,350
Cartagena
Cartagena2 stops$666
Quito
Quito2 stops$678
Guayaquil
Guayaquil2 stops$751

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
1:00 pm - 11:05 pm
MYR
-
BOG
10h 05m
1 stop
United Airlines Logo
8:15 am - 10:37 am
BOG
-
MYR
26h 22m
2 stops
$582United Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
1:00 pm - 11:05 pm
MYR
-
BOG
10h 05m
1 stop
United Airlines Logo
9:48 am - 4:49 pm
BOG
-
MYR
31h 01m
1 stop
$585United Airlines
Sun, Jun 28 - Sun, Jul 5
Multiple Airlines Logo
3:53 pm - 2:45 am
MYR
-
BOG
11h 52m
1 stop
Multiple Airlines Logo
4:05 pm - 7:50 am
BOG
-
MYR
14h 45m
1 stop
$603Multiple Airlines
Mon, Jun 22 - Fri, Jul 10
American Airlines Logo
8:41 pm - 11:20 am
MYR
-
BOG
15h 39m
2 stops
American Airlines Logo
12:25 pm - 8:36 am
BOG
-
MYR
19h 11m
2 stops
$615American Airlines
Mon, Jun 22 - Mon, Jun 29
Delta Logo
6:00 am - 8:10 pm
MYR
-
BOG
15h 10m
2 stops
Delta Logo
8:40 am - 10:44 am
BOG
-
MYR
25h 04m
2 stops
$638Delta
Mon, Jun 22 - Mon, Jun 29
Delta Logo
7:57 pm - 7:15 pm
MYR
-
BOG
24h 18m
1 stop
Delta Logo
8:40 am - 10:44 am
BOG
-
MYR
25h 04m
2 stops
$643Delta
Mon, Jul 20 - Thu, Jul 23
American Airlines Logo
4:16 pm - 12:35 pm
MYR
-
CTG
21h 19m
2 stops
American Airlines Logo
3:17 pm - 11:22 am
CTG
-
MYR
19h 05m
2 stops
$666American Airlines
Tue, Sep 1 - Wed, Sep 9
LATAM Airlines Logo
6:00 am - 9:35 pm
MYR
-
LIM
16h 35m
2 stops
LATAM Airlines Logo
12:05 pm - 11:39 pm
LIM
-
MYR
10h 34m
1 stop
$715LATAM Airlines
Mon, Nov 9 - Thu, Nov 12
LATAM Airlines Logo
6:00 am - 4:58 am
MYR
-
UIO
22h 58m
2 stops
LATAM Airlines Logo
7:00 pm - 5:55 pm
UIO
-
MYR
22h 55m
2 stops
$748LATAM Airlines
Mon, Jun 8 - Mon, Jun 15
Multiple Airlines Logo
10:00 am - 9:25 pm
MYR
-
MDE
12h 25m
1 stop
Multiple Airlines Logo
6:20 pm - 9:05 am
MDE
-
MYR
37h 45m
2 stops
$933Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to South America is January, when tickets cost $0 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $682 and $676 respectively.

Good to know

Low seasonFebruary
Cheapest flight$275
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Myrtle Beach to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8447 reviews
7.8Entertainment
8.1Boarding
8.5Crew
7.8Comfort
7.2Food
Airline reviews

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

10.0 ExcellentBenjamin, May 2026
CLT - MSP
Read more Delta reviews

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

Everything you need to know for your flight to South America

Information on your arrival and departure airports