$111 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$366
Bogotá
Bogotá1 stop$356
Santiago
Santiago3 stops$639
Quito
Quito2 stops$894
Guayaquil
Guayaquil2 stops$1,040
Lima
Lima2 stops$366
Bogotá
Bogotá1 stop$356
Santiago
Santiago3 stops$639
Quito
Quito2 stops$894
Guayaquil
Guayaquil2 stops$1,040

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Thu, Mar 19 - Wed, Mar 25
Spirit Airlines Logo
6:28 pm - 12:21 am
MYR
-
MDE
6h 53m
1 stop
Spirit Airlines Logo
1:17 am - 5:33 pm
MDE
-
MYR
15h 16m
1 stop
$254Spirit Airlines
Thu, Mar 19 - Wed, Mar 25
Spirit Airlines Logo
6:28 pm - 12:52 pm
MYR
-
MDE
19h 24m
2 stops
Spirit Airlines Logo
1:17 am - 5:33 pm
MDE
-
MYR
15h 16m
1 stop
$317Spirit Airlines
Wed, May 13 - Tue, May 19
Spirit Airlines Logo
7:51 pm - 12:42 am
MYR
-
MDE
5h 51m
1 stop
Spirit Airlines Logo
1:37 am - 9:42 am
MDE
-
MYR
7h 05m
1 stop
$336Spirit Airlines
Mon, Mar 2 - Sat, Mar 7
Spirit Airlines Logo
9:09 am - 2:10 pm
MYR
-
BOG
29h 01m
1 stop
Spirit Airlines Logo
3:06 pm - 7:13 am
BOG
-
MYR
16h 07m
1 stop
$356Spirit Airlines
Sun, Mar 29 - Tue, Apr 7
Spirit Airlines Logo
12:05 pm - 9:35 pm
MYR
-
LIM
34h 30m
2 stops
Spirit Airlines Logo
10:35 pm - 5:33 pm
LIM
-
MYR
17h 58m
1 stop
$366Spirit Airlines
Sun, Feb 22 - Sun, Mar 1
Multiple Airlines Logo
9:09 am - 9:40 pm
MYR
-
MDE
12h 31m
1 stop
Multiple Airlines Logo
1:00 pm - 8:13 am
MDE
-
MYR
19h 13m
1 stop
$374Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
6:28 pm - 1:11 pm
MYR
-
BOG
19h 43m
1 stop
Multiple Airlines Logo
11:00 am - 5:33 pm
BOG
-
MYR
29h 33m
2 stops
$380Multiple Airlines
Wed, Jun 17 - Thu, Jun 25
LATAM Airlines Logo
1:05 pm - 5:00 am
MYR
-
LIM
16h 55m
2 stops
LATAM Airlines Logo
12:10 am - 10:09 am
LIM
-
MYR
32h 59m
2 stops
$640LATAM Airlines
Fri, Mar 20 - Thu, Mar 26
LATAM Airlines Logo
6:54 pm - 7:40 am
MYR
-
SCL
11h 46m
1 stop
LATAM Airlines Logo
12:20 am - 9:33 am
SCL
-
MYR
34h 13m
2 stops
$900LATAM Airlines
Thu, Apr 9 - Sun, Apr 12
United Airlines Logo
11:57 am - 2:30 am
MYR
-
MAO
14h 33m
2 stops
United Airlines Logo
3:35 am - 10:18 am
MAO
-
MYR
30h 43m
2 stops
$1,386United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($254) and United Airlines ($1,386).

Good to know

Low seasonAugust
Cheapest flight$111
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 52% increase in price.
Flight from Myrtle Beach to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8139 reviews
7.2Food
8.5Crew
8.1Boarding
7.9Comfort
7.8Entertainment
Airline reviews

I was given middle seat on this flight and prior Boston to Seoul flight That is a problem for long flights, Kayak system did not give me a change to select my seats and assigned me middle seats regardless of my elevated status in Delta. This needs immediate attention.

2.0 MediocreAlparda, Feb 2026
BOS - ICN
Read more Delta reviews

I was given middle seat on this flight and prior Boston to Seoul flight That is a problem for long flights, Kayak system did not give me a change to select my seats and assigned me middle seats regardless of my elevated status in Delta. This needs immediate attention.

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The flight was comfortable and uneventful, which is what I desire

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

All of our flights were canceled, though every other airline was flying out and in

We were on the tarmac waiting for a gate at Logan for 40, minutes. The crew handled it well. Can't blame the airline.

That gate is like a ducking shelter at Newark No where to sit Outlets that don’t work Bathrooms that are dirty

Everything was good. On time, boarding fast, flight attendants friendly.

Great, but seats are terrible. Way too cramped for any human.

Spirit has always and will always stink. Absolute worst airline around.

It was smooth sailing snags we had a really smooth landing and a great flight!

I know it's a low-cost airline. However, the seats are very basic, so after two hours of travel, they feel very uncomfortable and cannot be reclined. The two flights from Bogota to Orlando and the return flight were very punctual. The check-in process on the app works very well. I really liked the self-check-in process for luggage at the Orlando airport; it was quick, easy, and very convenient.

The entire experience was so surprisingly pleasant. And the blocked extra seat between us was such an amazing and nice bonus. Great experience all around and I can’t wait to fly with spirit again!

Everything was OK, the deicing took a long time, our connections were almost missed.

Everything you need to know for your flight to South America

Information on your arrival and departure airports