$164 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima3 stops$647
Bogotá
Bogotá2 stops$355
Santiago
Santiago3 stops$771
Cartagena
Cartagena1 stop$373
Quito
Quito1 stop$639
Guayaquil
Guayaquil2 stops$1,219
Lima
Lima3 stops$647
Bogotá
Bogotá2 stops$355
Santiago
Santiago3 stops$771
Cartagena
Cartagena1 stop$373
Quito
Quito1 stop$639
Guayaquil
Guayaquil2 stops$1,219

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Thu, May 28 - Sun, May 31
Multiple Airlines Logo
6:00 am - 5:30 pm
MYR
-
BOG
12h 30m
2 stops
Multiple Airlines Logo
6:35 am - 8:36 pm
BOG
-
MYR
13h 01m
2 stops
$355Multiple Airlines
Thu, May 28 - Sun, May 31
Multiple Airlines Logo
6:00 am - 11:25 pm
MYR
-
BOG
18h 25m
3 stops
Multiple Airlines Logo
6:35 am - 8:36 pm
BOG
-
MYR
13h 01m
2 stops
$360Multiple Airlines
Thu, May 7 - Thu, May 14
Spirit Airlines Logo
6:00 am - 12:26 pm
MYR
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 8:36 pm
CTG
-
MYR
6h 05m
1 stop
$373Spirit Airlines
Thu, May 7 - Thu, May 14
Spirit Airlines Logo
9:39 pm - 12:26 pm
MYR
-
CTG
15h 47m
2 stops
Spirit Airlines Logo
1:31 pm - 8:36 pm
CTG
-
MYR
6h 05m
1 stop
$457Spirit Airlines
Thu, May 14 - Thu, May 21
American Airlines Logo
12:05 pm - 10:32 pm
MYR
-
UIO
11h 27m
2 stops
American Airlines Logo
6:00 am - 8:01 pm
UIO
-
MYR
13h 01m
2 stops
$649American Airlines
Mon, May 11 - Mon, May 25
American Airlines Logo
6:31 pm - 1:08 pm
MYR
-
CLO
19h 37m
2 stops
American Airlines Logo
11:59 pm - 9:47 pm
CLO
-
MYR
20h 48m
2 stops
$658American Airlines
Wed, Aug 19 - Thu, Aug 27
Delta Logo
2:15 pm - 5:00 am
MYR
-
LIM
15h 45m
1 stop
Delta Logo
12:05 pm - 11:39 pm
LIM
-
MYR
10h 34m
1 stop
$665Delta
Thu, May 14 - Wed, May 20
Delta Logo
11:43 am - 6:59 pm
MYR
-
UIO
8h 16m
1 stop
Delta Logo
12:59 am - 12:40 pm
UIO
-
MYR
10h 41m
1 stop
$667Delta
Tue, Aug 18 - Tue, Aug 25
LATAM Airlines Logo
6:00 am - 8:55 pm
MYR
-
LIM
15h 55m
2 stops
LATAM Airlines Logo
12:15 am - 11:39 pm
LIM
-
MYR
22h 24m
2 stops
$670LATAM Airlines
Wed, Sep 9 - Tue, Sep 15
LATAM Airlines Logo
6:45 pm - 6:59 pm
MYR
-
UIO
25h 14m
1 stop
LATAM Airlines Logo
12:59 am - 10:09 am
UIO
-
MYR
8h 10m
1 stop
$675LATAM Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($373) and American Airlines ($649).

Good to know

Low seasonAugust
Cheapest flight$164
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 49% increase in price.
Flight from Myrtle Beach to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8404 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.8Entertainment
7.2Food
Airline reviews

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

8.0 ExcellentBarbie, Apr 2026
BOS - SFO
Read more Delta reviews

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

Crew was great. Near on time departure and early arrival. Snacks are always meh. Not a fan of the "pay for everything including miles " proposal unless base flight rate going to be 100 bucks.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

Overall Good! The weather delayed our takeoff from Atlanta and our arrival in Miami! If Mother Nature can mess up a flight she will do it every time!

The flight was smooth, the crew was great but the plane was quite old

Everything was great until I lost my water bottle and they can’t seem to locate it. I know I left it on the plane though.

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Okay considering we had weather delays which the Pilot notified us of immediately!

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Everything you need to know for your flight to South America

Information on your arrival and departure airports