$238 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$715
Bogotá
Bogotá2 stops$562
Santiago
Santiago2 stops$1,019
Cartagena
Cartagena2 stops$597
Quito
Quito2 stops$725
Lima
Lima2 stops$715
Bogotá
Bogotá2 stops$562
Santiago
Santiago2 stops$1,019
Cartagena
Cartagena2 stops$597
Quito
Quito2 stops$725

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Fri, Jul 24 - Tue, Jul 28
American Airlines Logo
8:44 pm - 1:10 pm
MYR
-
BOG
17h 26m
2 stops
American Airlines Logo
2:10 pm - 10:54 am
BOG
-
MYR
19h 44m
2 stops
$562American Airlines
Fri, Jul 24 - Mon, Jul 27
American Airlines Logo
8:44 pm - 11:20 am
MYR
-
BOG
15h 36m
2 stops
American Airlines Logo
12:25 am - 11:16 pm
BOG
-
MYR
21h 51m
1 stop
$591American Airlines
Wed, Nov 11 - Wed, Nov 18
United Airlines Logo
11:30 am - 11:05 pm
MYR
-
BOG
11h 35m
1 stop
United Airlines Logo
9:48 am - 10:20 am
BOG
-
MYR
24h 32m
1 stop
$595United Airlines
Sun, Aug 23 - Thu, Aug 27
United Airlines Logo
10:23 am - 9:10 pm
MYR
-
MDE
35h 47m
2 stops
United Airlines Logo
9:45 am - 9:44 am
MDE
-
MYR
46h 59m
2 stops
$712United Airlines
Tue, Sep 1 - Tue, Sep 8
LATAM Airlines Logo
6:00 am - 8:20 pm
MYR
-
LIM
15h 20m
2 stops
LATAM Airlines Logo
12:10 am - 9:42 pm
LIM
-
MYR
20h 32m
2 stops
$715LATAM Airlines
Wed, Aug 5 - Wed, Aug 12
Delta Logo
7:02 pm - 1:15 pm
MYR
-
CTG
19h 13m
1 stop
Delta Logo
5:30 am - 11:30 pm
CTG
-
MYR
17h 00m
2 stops
$719Delta
Tue, Sep 1 - Wed, Sep 9
LATAM Airlines Logo
6:00 am - 9:35 pm
MYR
-
LIM
16h 35m
2 stops
LATAM Airlines Logo
12:05 pm - 10:09 am
LIM
-
MYR
21h 04m
1 stop
$723LATAM Airlines
Mon, Aug 17 - Mon, Aug 24
Delta Logo
7:02 pm - 1:15 pm
MYR
-
CTG
19h 13m
1 stop
Delta Logo
4:25 am - 11:30 pm
CTG
-
MYR
18h 05m
2 stops
$750Delta
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
7:49 pm - 12:50 pm
MYR
-
AXM
42h 01m
2 stops
Multiple Airlines Logo
10:15 pm - 6:53 pm
AXM
-
MYR
19h 38m
2 stops
$796Multiple Airlines
Tue, Oct 20 - Mon, Dec 14
Multiple Airlines Logo
10:45 am - 2:10 pm
MYR
-
CLO
28h 25m
2 stops
Multiple Airlines Logo
1:30 am - 9:50 am
CLO
-
MYR
8h 20m
1 stop
$834Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to South America is August, when tickets cost $355 (return) on average. On the other hand, the most expensive months are January and October, when the average cost of round-trip tickets is $764 and $745 respectively.

Good to know

Low seasonJanuary
Cheapest flight$238
Best time to beat the crowds but there is an average 23% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Myrtle Beach to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8440 reviews
7.8Entertainment
8.1Boarding
7.2Food
7.8Comfort
8.5Crew
Airline reviews

Not really a “Delta” problem but worth mentioning: Boarding was a difficult process. TSA seemed understaffed and Pre-Check took longer than regular TSA. The supervisor was frazzled and yelled at travelers. Once through TSA, we had to put our carry-ons through another x-ray machine. Then queue up to board with both boarding pass and ID. Then, when we got to the stairs on the tarmac, we had to show our boarding pass again. Maybe this is just normal for Kona since the terminal is outdoors (but still a “secured” area).

6.0 GoodMary, Jun 2026
KOA - SEA
Read more Delta reviews

Not really a “Delta” problem but worth mentioning: Boarding was a difficult process. TSA seemed understaffed and Pre-Check took longer than regular TSA. The supervisor was frazzled and yelled at travelers. Once through TSA, we had to put our carry-ons through another x-ray machine. Then queue up to board with both boarding pass and ID. Then, when we got to the stairs on the tarmac, we had to show our boarding pass again. Maybe this is just normal for Kona since the terminal is outdoors (but still a “secured” area).

flight was delayed 4+ hours. there was really no understanding of why? weather? the last hour of delay was post boarding. pilot seat was broken. was that the real reason? nonetheless, long day of inconveniences.

Love me some Delta. One of the few airlines to recognize and support veterans. Easy boarding, flight was on time and arrived early and the flight attendants were excellent on this flight.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.

The plane was frigid, and leaked water from the ceiling all over me and my seat.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Everything you need to know for your flight to South America

Information on your arrival and departure airports