$184 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$589
Bogotá
Bogotá1 stop$348
Santiago
Santiago2 stops$1,031
Cartagena
Cartagena2 stops$781
Quito
Quito2 stops$602
Guayaquil
Guayaquil2 stops$834
Lima
Lima2 stops$589
Bogotá
Bogotá1 stop$348
Santiago
Santiago2 stops$1,031
Cartagena
Cartagena2 stops$781
Quito
Quito2 stops$602
Guayaquil
Guayaquil2 stops$834

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Sat, Apr 18 - Sat, Apr 25
Multiple Airlines Logo
4:40 pm - 1:12 pm
MYR
-
BOG
21h 32m
1 stop
Multiple Airlines Logo
2:07 pm - 11:29 pm
BOG
-
MYR
8h 22m
1 stop
$348Multiple Airlines
Sat, Apr 18 - Sat, Apr 25
Multiple Airlines Logo
8:43 pm - 9:00 am
MYR
-
BOG
13h 17m
2 stops
Multiple Airlines Logo
2:07 pm - 11:29 pm
BOG
-
MYR
8h 22m
1 stop
$440Multiple Airlines
Wed, May 13 - Sun, May 24
American Airlines Logo
9:14 am - 8:15 pm
MYR
-
MDE
12h 01m
2 stops
American Airlines Logo
11:59 pm - 12:28 pm
MDE
-
MYR
11h 29m
2 stops
$587American Airlines
Mon, Apr 6 - Thu, Apr 16
American Airlines Logo
5:10 am - 10:16 pm
MYR
-
UIO
18h 06m
2 stops
American Airlines Logo
7:05 am - 11:57 pm
UIO
-
MYR
15h 52m
2 stops
$602American Airlines
Sat, Apr 18 - Sat, Apr 25
United Airlines Logo
3:15 pm - 4:54 am
MYR
-
BOG
14h 39m
2 stops
United Airlines Logo
8:30 am - 10:18 am
BOG
-
MYR
24h 48m
2 stops
$604United Airlines
Mon, Apr 13 - Thu, Apr 16
United Airlines Logo
3:15 pm - 4:54 am
MYR
-
BOG
14h 39m
2 stops
United Airlines Logo
8:30 am - 2:17 pm
BOG
-
MYR
28h 47m
2 stops
$612United Airlines
Mon, Apr 6 - Wed, Apr 15
Delta Logo
10:23 am - 4:43 am
MYR
-
UIO
19h 20m
2 stops
Delta Logo
12:59 am - 12:14 am
UIO
-
MYR
22h 15m
1 stop
$617Delta
Mon, Apr 6 - Wed, Apr 15
Delta Logo
6:54 pm - 6:59 pm
MYR
-
UIO
25h 05m
1 stop
Delta Logo
12:59 am - 12:14 am
UIO
-
MYR
22h 15m
1 stop
$618Delta
Tue, May 19 - Mon, May 25
Spirit Airlines Logo
11:52 am - 9:11 pm
MYR
-
LIM
10h 19m
1 stop
Spirit Airlines Logo
10:18 pm - 4:31 pm
LIM
-
MYR
17h 13m
1 stop
$649Spirit Airlines
Sat, Apr 18 - Sat, Apr 25
Spirit Airlines Logo
11:52 am - 9:11 pm
MYR
-
LIM
10h 19m
1 stop
Spirit Airlines Logo
10:18 pm - 11:29 pm
LIM
-
MYR
24h 11m
1 stop
$654Spirit Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on American Airlines ($580) and United Airlines ($604).

Good to know

Low seasonAugust
Cheapest flight$184
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 51% increase in price.
Flight from Myrtle Beach to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8245 reviews
7.2Food
7.9Comfort
7.8Entertainment
8.5Crew
8.1Boarding
Airline reviews

The whole experience was excellent. As it most often is with Delta

10.0 ExcellentRay, Mar 2026
LGA - MCO
Read more Delta reviews

The whole experience was excellent. As it most often is with Delta

Cabin was not pressurized properly. Several passengers had respiratory difficulties.

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Flight was warm for first few hours and quite rough

Seat was extremely hard which made even a short 1 hour 20 minute flight fairly uncomfortable.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

The bag situation was confusing. I didn’t know I had to pay for Carry ons. The seats were uncomfortable and there was no entertainment

Spirit Airlines at Laguardia is a small terminal so it is quick to get to your gate and to get your luggage. The flight is short enough to orlando and the price was very inexpensive. The seats do not move so you can't recline. Drinks and snakcks should be complimentary.

Bad. I know TSA is a mess right now but they “overbooked” the flight and almost didn’t let 10 of us on. Can’t put even a normal backpack under the seat, tray table is barely a foot wide, have to pay for literally everything. Apparently you can bid on your seats, too, so really the baseline ticket only covers the possibility of maybe getting on the plane. The staff were nice though, can only imagine the stress they are under.

I was double booked for my ticket- they have record of it and admitted to their error but wouldn’t let me board until I paid once again for the fare- have documentation of their mistake -

The flight time did not match my original email on time of flight. Missed the first flight. The representative I got on the phone was so incompetent it was unbelievable. My guess is it was AI but it told me it was not AI. They did get me rebooked which I was very thankful of. The return flight was delayed because of staffing issues for the plane and when we reached our destination the jet bridge would not work so we sat on the plane another 40 minutes. I did get to my destination and I did get home but not a good experience.

My flight was cancelled I missed time at work and got a parking ticket

It was terrible. I had to pay again once I got to the airport because they said they never received the payment.

Customer service online / on the phone are horrible. Flight crew is great but gate agents and customer service are terrible

bought basic spirit fares, add checked bags - like the up front info on website about this. bring your own snacks, buy a soda after TSA security to bring with you, or buy on the plane (limited selection) all in all, a good experience

I cannot effectively rate the food and drink as I had not. Otherwise, the trip was fine. The seats were nice, the crew was fine. They could smile once in a while. They all look like they were mad.

Everything you need to know for your flight to South America

Information on your arrival and departure airports