$162 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$618
Bogotá
Bogotá1 stop$406
Santiago
Santiago2 stops$1,007
Cartagena
Cartagena2 stops$540
Quito
Quito2 stops$729
Guayaquil
Guayaquil1 stop$351
Lima
Lima2 stops$618
Bogotá
Bogotá1 stop$406
Santiago
Santiago2 stops$1,007
Cartagena
Cartagena2 stops$540
Quito
Quito2 stops$729
Guayaquil
Guayaquil1 stop$351

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Tue, Apr 21 - Fri, Apr 24
Multiple Airlines Logo
5:55 pm - 11:04 pm
MYR
-
GYE
30h 09m
1 stop
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$351Multiple Airlines
Tue, Apr 21 - Fri, Apr 24
Spirit Airlines Logo
5:55 pm - 11:04 pm
MYR
-
GYE
30h 09m
1 stop
Spirit Airlines Logo
11:59 pm - 11:29 pm
GYE
-
MYR
22h 30m
1 stop
$352Spirit Airlines
Wed, Apr 22 - Fri, Apr 24
Multiple Airlines Logo
11:28 am - 11:04 pm
MYR
-
GYE
12h 36m
1 stop
Multiple Airlines Logo
11:59 pm - 8:55 pm
GYE
-
MYR
19h 56m
1 stop
$356Multiple Airlines
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
11:52 am - 11:04 pm
MYR
-
GYE
12h 12m
1 stop
Multiple Airlines Logo
6:50 pm - 11:29 pm
GYE
-
MYR
27h 39m
2 stops
$387Multiple Airlines
Fri, Jul 10 - Sat, Jul 18
American Airlines Logo
6:19 pm - 12:35 pm
MYR
-
CTG
19h 16m
2 stops
American Airlines Logo
1:35 pm - 10:54 am
CTG
-
MYR
20h 19m
2 stops
$587American Airlines
Thu, Aug 6 - Tue, Aug 11
American Airlines Logo
5:23 am - 8:15 pm
MYR
-
MDE
15h 52m
2 stops
American Airlines Logo
1:50 pm - 8:56 am
MDE
-
MYR
18h 06m
2 stops
$590American Airlines
Fri, Jul 10 - Sat, Jul 18
LATAM Airlines Logo
4:16 pm - 1:02 pm
MYR
-
CTG
21h 46m
1 stop
LATAM Airlines Logo
2:33 pm - 10:47 am
CTG
-
MYR
19h 14m
1 stop
$651LATAM Airlines
Fri, Jul 10 - Sat, Jul 18
LATAM Airlines Logo
4:16 pm - 6:30 pm
MYR
-
CTG
27h 14m
2 stops
LATAM Airlines Logo
2:33 pm - 10:47 am
CTG
-
MYR
19h 14m
1 stop
$657LATAM Airlines
Fri, May 15 - Fri, May 22
United Airlines Logo
6:00 pm - 11:00 pm
MYR
-
CTG
30h 00m
2 stops
United Airlines Logo
9:45 am - 9:18 am
CTG
-
MYR
22h 33m
2 stops
$862United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
11:00 am - 2:30 am
MYR
-
MAO
15h 30m
2 stops
United Airlines Logo
3:35 am - 10:18 am
MAO
-
MYR
30h 43m
2 stops
$1,744United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($406) and LATAM Airlines ($572).

Good to know

Low seasonAugust
Cheapest flight$162
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 49% increase in price.
Flight from Myrtle Beach to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1908 reviews
7.5Boarding
6.7Food
8.0Crew
7.3Comfort
7.0Entertainment
Airline reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

10.0 ExcellentYelen, Mar 2026
ATL - TPA
Read more LATAM Airlines reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

The worst. My flight was canceled :-- by email! -- at 10pm, just 8 hours prior to departure. Normally, given the early departure time, I would've been asleep. I was lucky to be awake and to be able to take action. Even worse, it turns out that the flight wasn't canceled (confirmed because I was at the airport and saw it loading), Spirit just canceled my reservation, probably because I got such a good rate! Utterly appalling. Notably, Spirit did not inform you (Kayak) of the change, so I kept getting alerts from you.

It was my first time flying with spirit. It was amazing. I loved it.

Horrible airline .. my flight was cancel , the only offer to flight next day was no good for me , representative from spirit advise everybody to buy the new ticket from southwest airline and spirit will pay back the money we spend on new ticket but after we did this they don’t want to pay us back , .. customer service is not help anybody Chat text messages it is horrible also , robots can’t answer and help u with anything … I send the complains to head quarter in Miami and department of transportation

Attention to detail. Luggage was lost in flight, after I confirmed it was connecting. Never made it to the destination airport.

The ticket price are reasonable, however, they can do better with the price on the luggage. Overall, I will continue using spirit.

That this is my second time the they cancel flights and they always wait until the last minute to let people know

The flight was supposed to leave at 6:22pm we are just now leaving the gate after deplaning twice at 1:07am.

Spirit is always late. Every single time. Always a different reason

They keep delaying and cancel at last moment and height was for you to get refund need to be in chat line for two hours. I complained to DOT. Never recommend this airline on Kayak please

First flight in along time with spirit! I’m honored to say this flight was excellent 😊

Everything you need to know for your flight to South America

Information on your arrival and departure airports