$125 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$551
Bogotá
Bogotá1 stop$347
Cartagena
Cartagena1 stop$314
Quito
Quito2 stops$602
Lima
Lima1 stop$551
Bogotá
Bogotá1 stop$347
Cartagena
Cartagena1 stop$314
Quito
Quito2 stops$602

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Sat, Mar 21 - Sun, Mar 29
Spirit Airlines Logo
6:28 pm - 12:21 am
MYR
-
MDE
6h 53m
1 stop
Spirit Airlines Logo
1:17 am - 5:33 pm
MDE
-
MYR
15h 16m
1 stop
$309Spirit Airlines
Sat, Apr 11 - Sat, Apr 18
Spirit Airlines Logo
6:28 pm - 12:06 pm
MYR
-
CTG
18h 38m
1 stop
Spirit Airlines Logo
1:11 pm - 9:41 am
CTG
-
MYR
19h 30m
1 stop
$314Spirit Airlines
Tue, Mar 24 - Wed, May 27
Multiple Airlines Logo
6:28 pm - 10:45 am
MYR
-
BOG
17h 17m
2 stops
Multiple Airlines Logo
9:40 pm - 9:41 am
BOG
-
MYR
11h 01m
2 stops
$383Multiple Airlines
Thu, Apr 9 - Thu, Apr 16
Multiple Airlines Logo
6:28 pm - 1:11 pm
MYR
-
BOG
19h 43m
1 stop
Multiple Airlines Logo
2:07 pm - 2:13 pm
BOG
-
MYR
23h 06m
1 stop
$385Multiple Airlines
Wed, May 13 - Wed, May 20
American Airlines Logo
6:04 am - 8:15 pm
MYR
-
MDE
15h 11m
2 stops
American Airlines Logo
6:00 am - 9:56 pm
MDE
-
MYR
14h 56m
2 stops
$583American Airlines
Mon, Apr 6 - Thu, Apr 16
American Airlines Logo
5:10 am - 10:16 pm
MYR
-
UIO
18h 06m
2 stops
American Airlines Logo
11:40 pm - 6:00 pm
UIO
-
MYR
17h 20m
2 stops
$602American Airlines
Mon, Apr 6 - Wed, Apr 15
Delta Logo
6:00 am - 4:43 am
MYR
-
UIO
23h 43m
2 stops
Delta Logo
12:59 am - 12:14 am
UIO
-
MYR
22h 15m
1 stop
$647Delta
Mon, Apr 6 - Wed, Apr 15
Delta Logo
6:54 pm - 6:59 pm
MYR
-
UIO
25h 05m
1 stop
Delta Logo
12:59 am - 12:14 am
UIO
-
MYR
22h 15m
1 stop
$648Delta
Sun, Jun 7 - Sun, Jun 14
LATAM Airlines Logo
7:50 pm - 9:40 pm
MYR
-
LIM
26h 50m
2 stops
LATAM Airlines Logo
1:00 pm - 7:04 pm
LIM
-
MYR
29h 04m
2 stops
$650LATAM Airlines
Fri, Apr 10 - Fri, Apr 17
LATAM Airlines Logo
6:00 am - 9:35 pm
MYR
-
LIM
16h 35m
2 stops
LATAM Airlines Logo
12:05 pm - 12:14 am
LIM
-
MYR
11h 09m
1 stop
$655LATAM Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to South America were found on Spirit Airlines ($309) and American Airlines ($583).

Good to know

Low seasonAugust
Cheapest flight$125
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 51% increase in price.
Flight from Myrtle Beach to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8238 reviews
7.2Food
8.5Crew
7.8Entertainment
7.9Comfort
8.1Boarding
Airline reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

10.0 ExcellentBob, Feb 2026
FLL - MSP
Read more Delta reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

The staff was frielndly. The plane was terrible, it was too small and should be decommissioned. There were no back seat screens at all. The only beverages we had a choice from was coffee, tea or water. The only bathroom in the back was behind the flight attendant's jump seat and wasn't working. And I literally felt like I was sitting on top of the guy next to me. It was terribly hot in the plane and we had to sit on the tarmac in Chicago for 1/2 hour due to congestion in Mpls. Wouldn't they have know that before they even boarded us so that we could have sat in comfort in the terminal?

Never got on it. Was re-routed through Detroit and am still in airports 12 hours later waiting for my connecting plane to arrive.

Delta has too many delays now days. It is 1:06 am now. I was supposed to land in Norfolk at 10:30 pm. I got re-booked through Detroit and I’m still in Detroit. I hope to be landed in Norfolk by 3am. I’ve been in airports for 12 hours as of right now. There is a weather delay now but most delays lately have been maintenance.

They charged late fees for selecting seats (no $0 options). They also changed my gate within the last half hour and are refusing to reimburse my costs to drive across the country with two small children in a rental car.

I was waiting in line for the restroom onboard, the flight attendant told me to step back two rows and stay on the carpet. She was rude and I expected a tik tok experience with me getting thrown off the plane. She was rude and frankly there was no where else to stand.

I needed a cheaper option than Southwest who are almost as bad as Spirit...did the check in the morning of the flight and assigned the last row, middle seat. Paid 20.00 at the airport for an exit row window in 19 and all 8 rows behind me which sold occupied on their seat map were empty....so they force to you to pay for a better seat....I was alone in row 19 and shortly after take off two huge fat people came and grabbed the other seats, I rang the call button for the attendant and said I paid 20.00 for this seat and they just moved in here...I either want to be reseated, or have them take their original seats or a refund of what I paid, the attendant made them move back to their original seats. Worst, worst worst airline in the air....never again, never again, never again.

It was cancelled a few hours before take off. Spirit has yet to confirm I will be refunded for the trip

gate agents with the different rules at the different airports. made me pay for my bag as a carry on instead of a personal item, yet it fit under the seat on the way from Indy to Ft Laud

charging $3 for really bad and cold coffee on airplane flight is ridiculous.

We flew Spirit because it was cheaper but the seats were so uncomfortable. I don;t need to be fed snacks on a plane but when it's a 3-4 hour trip then at least a drink is nice. The flight attendants had nothing to do the whole flight except for gossip loudly to each other right behind our seats, and they talked so much my husband couldn't even rest! I was fine with no tv or entertainment but the seats were so uncomfortable with no recline, no padding, and I am short but even for me to leg room was tough for a 3-4 hour trip. We probably would fly spirit again if we had to, but it's definitely not our favorite!

There was absolutely nothing good about this fight. They delayed us for over 2 hours to give our plane to a flight going to Tampa. By the time we got to norfolk conditions were too bad to land so they took us to Charlotte to refuel so they could fly back to Fort lauderdale. There was almost no communication from the pilot, no wifi, no chargers, and they wouldn't even give us free water when we were stuck in Charlotte refueling.

Checking in and getting to gate fast and leasy at Laguardia airport. There is no entertainment on the plane and food was for purchase. Great experience flying with spirit

The flight itself and the crew were great. Sitting on the tarmac for over an hour until our gate opened up was really frustrating. Missed our scheduled bus and got home two hours later

Everything you need to know for your flight to South America

Information on your arrival and departure airports