$288 Find Cheap Flights from Myrtle Beach to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$715
Bogotá
Bogotá2 stops$683
Santiago
Santiago2 stops$1,160
Cartagena
Cartagena2 stops$702
Quito
Quito2 stops$642
Lima
Lima2 stops$715
Bogotá
Bogotá2 stops$683
Santiago
Santiago2 stops$1,160
Cartagena
Cartagena2 stops$702
Quito
Quito2 stops$642

Book Cheap Myrtle Beach to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to South America

Mon, Nov 16 - Mon, Jan 11
American Airlines Logo
8:07 pm - 2:20 pm
MYR
-
CLO
18h 13m
2 stops
American Airlines Logo
3:20 pm - 11:35 am
CLO
-
MYR
20h 15m
2 stops
$661American Airlines
Sun, Jun 21 - Sun, Jun 28
American Airlines Logo
6:28 pm - 1:18 pm
MYR
-
CLO
19h 50m
2 stops
American Airlines Logo
11:59 pm - 8:27 pm
CLO
-
MYR
19h 28m
2 stops
$678American Airlines
Thu, Oct 8 - Tue, Oct 13
United Airlines Logo
3:20 pm - 4:54 am
MYR
-
BOG
38h 34m
2 stops
United Airlines Logo
8:30 am - 10:37 am
BOG
-
MYR
25h 07m
2 stops
$683United Airlines
Thu, Oct 8 - Tue, Oct 13
United Airlines Logo
3:20 pm - 7:20 pm
MYR
-
BOG
29h 00m
2 stops
United Airlines Logo
7:20 am - 9:54 am
BOG
-
MYR
25h 34m
1 stop
$692United Airlines
Fri, Jun 12 - Mon, Jun 15
LATAM Airlines Logo
6:00 am - 8:10 pm
MYR
-
BOG
15h 10m
2 stops
LATAM Airlines Logo
7:05 pm - 11:59 pm
BOG
-
MYR
27h 54m
2 stops
$709LATAM Airlines
Tue, Sep 1 - Wed, Sep 9
Delta Logo
6:00 am - 8:20 pm
MYR
-
LIM
15h 20m
2 stops
Delta Logo
8:55 am - 10:09 am
LIM
-
MYR
24h 14m
2 stops
$715Delta
Thu, Jul 9 - Thu, Jul 16
LATAM Airlines Logo
6:00 am - 1:09 pm
MYR
-
CTG
8h 09m
1 stop
LATAM Airlines Logo
2:30 pm - 11:55 pm
CTG
-
MYR
8h 25m
1 stop
$718LATAM Airlines
Sun, Aug 23 - Sat, Sep 19
Delta Logo
7:02 pm - 8:20 pm
MYR
-
LIM
26h 18m
2 stops
Delta Logo
8:55 am - 10:13 am
LIM
-
MYR
24h 18m
2 stops
$746Delta
Sat, Jul 11 - Sat, Jul 18
Multiple Airlines Logo
4:21 pm - 4:55 pm
MYR
-
MDE
25h 34m
2 stops
Multiple Airlines Logo
6:35 am - 8:55 am
MDE
-
MYR
25h 20m
1 stop
$899Multiple Airlines
Thu, Jun 18 - Sun, Jun 21
Multiple Airlines Logo
9:07 pm - 10:55 am
MYR
-
MDE
14h 48m
2 stops
Multiple Airlines Logo
6:35 am - 9:05 am
MDE
-
MYR
25h 30m
1 stop
$1,004Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to South America flights

Get data-powered insights and trends into flights from Myrtle Beach to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to South America is October, when tickets cost $0 (return) on average. On the other hand, the most expensive months are January and December, when the average cost of round-trip tickets is $764 and $682 respectively.

Good to know

Low seasonAugust
Cheapest flight$288
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Myrtle Beach to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8420 reviews
8.1Boarding
7.2Food
7.8Comfort
8.5Crew
7.8Entertainment
Airline reviews

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

6.0 GoodAnonymous, May 2026
ATL - ECP
Read more Delta reviews

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

The crew were efficient. The pilots seemed professional. It was a bit chilly in our seats. The sheet provided weren’t very helpful.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

The Boarding process was great. Particularly since my wife and I require assistance. The flight attendants were amazing. We travel frequently; they honestly were a cut above. 😀

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

Everything you need to know for your flight to South America

Information on your arrival and departure airports