MSY - TYS

$127 Find Cheap Flights from New Orleans to Knoxville - Compare and Save

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Everything you should know

Cheapest round-trip
$269
Typical prices: $356-$513
Multiple Airlines
Tue 12/4Thu 12/6
MSY - TYS • 2 stops
Cheapest non-stop
$1,061
Typical prices: $417-$857
Southwest
Tue 11/20Thu 11/22
MSY - TYS • Non-stop
Nonstop flights
There are currently no direct flights between New Orleans and Knoxville. You'll need to take a connecting flight to reach the destination.
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When to travel
Cheapest • 23% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $329 (round-trip)
Shortest trip • 3h 58m (one-way)
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Flight Deals

Cheap Flights from New Orleans to Knoxville (MSY-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from New Orleans to Knoxville

Fri, Dec 4 - Sun, Dec 6
Multiple Airlines Logo
9:26 am - 10:37 amMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
24h 11m2 stops Atlanta Hartsfield-Jackson Fort Lauderdale
Multiple Airlines Logo
11:00 am - 6:53 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
8h 53m1 stop Jacksonville
$269Multiple Airlines
Wed, Nov 25 - Thu, Nov 26
United Airlines Logo
2:25 pm - 8:54 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 29m1 stop Chicago O'Hare Intl
United Airlines Logo
5:45 am - 10:15 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 30m1 stop Washington, D.C. Dulles Intl
$282United Airlines
Sun, Dec 13 - Mon, Dec 21
Multiple Airlines Logo
9:40 am - 8:31 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
9h 51m1 stop Jacksonville
Multiple Airlines Logo
8:32 pm - 3:04 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
19h 32m2 stops Fort Lauderdale Tampa
$285Multiple Airlines
Thu, Feb 25 - Mon, Mar 1
American Airlines Logo
5:22 am - 2:02 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
7h 40m1 stop Dallas/Fort Worth
American Airlines Logo
5:30 am - 10:06 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 36m1 stop Dallas/Fort Worth
$287American Airlines
Fri, Nov 27 - Fri, Dec 4
American Airlines Logo
3:45 pm - 11:32 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 47m1 stop Dallas/Fort Worth
American Airlines Logo
8:00 pm - 11:59 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
4h 59m1 stop Charlotte Douglas
$287American Airlines
Thu, Jan 28 - Mon, Feb 1
American Airlines Logo
7:27 am - 1:55 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 28m1 stop Dallas/Fort Worth
American Airlines Logo
2:45 pm - 7:34 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 49m1 stop Dallas/Fort Worth
$287American Airlines
Thu, Feb 25 - Mon, Mar 1
Southwest Logo
7:35 am - 5:45 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
9h 10m2 stops Houston Hobby Dallas Love Field
Southwest Logo
3:50 pm - 11:20 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
8h 30m1 stop Denver Intl
$292Southwest
Thu, Jan 28 - Mon, Feb 1
Southwest Logo
10:15 am - 6:35 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
7h 20m2 stops Austin Bergstrom Nashville Intl
Southwest Logo
4:40 pm - 10:00 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 20m1 stop Nashville Intl
$292Southwest
Fri, Dec 11 - Mon, Dec 14
Delta Logo
6:21 pm - 11:57 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
4h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:26 pm - 12:07 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 41m1 stop Atlanta Hartsfield-Jackson
$305Delta
Fri, Dec 11 - Sun, Dec 13
Delta Logo
6:21 pm - 11:57 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
4h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:32 pm - 4:06 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
4h 34m1 stop Atlanta Hartsfield-Jackson
$330Delta
Booking Insights

Price, demand and travel trends for New Orleans to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from New Orleans to Knoxville?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from New Orleans to Knoxville. It’s 17% cheaper than the average day, while Sunday is the most expensive, with prices 22% higher.

What’s the cheapest month to fly from New Orleans to Knoxville?

•October is the cheapest month to fly from New Orleans to Knoxville at $329 round-trip.
•March ($690) and July ($636) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 109% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Key details for New Orleans to Knoxville flights

Low season

February

Cheapest flight

$127
Beat the crowds with an average 40% drop in travelers.
The most popular month to fly with an average 20% increase in travelers.
One-way flight from New Orleans to Knoxville

When to book flights from New Orleans to Knoxville

Are your dates flexible? Find out the best times to travel from New Orleans to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your New Orleans to Knoxville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from New Orleans to Knoxville?

    These are the earliest and latest flight times available from New Orleans to Knoxville:

    • Earliest: departs at 8:05 am and lands at 10:05 am
    • Latest: departs at 2:30 pm and lands at 4:30 pm.

    The flight takes about 2h.

  • What cabin classes can I book on flights from New Orleans to Knoxville?

    Only Economy Class is available on flights from New Orleans to Knoxville.

  • How long is a flight from New Orleans to Knoxville?

    A nonstop flight from New Orleans to Knoxville takes 2h, covering 541 miles.

  • Do I need a passport to fly from New Orleans to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a New Orleans to Knoxville flight?

    Round-trip flights from New Orleans to Knoxville range from $356 to $513, with an average of $426 over the past 12 months. Anything below $356 counts as a good deal.

  • How much can I save by taking a layover when flying from New Orleans to Knoxville?

    On this route, layover flights are cheaper than nonstop options on average. Layover fares average $329 round-trip via Orlando (MCO), compared to $787 for nonstop.

  • What is the standard checked-bag allowance on flights from New Orleans to Knoxville?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $50–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from New Orleans to Knoxville?

    The Embraer 175 family is used most often on this route, operated mainly by American Airlines. Other aircraft seen on the route include Boeing 737 MAX 8 variants.

  • Have flight prices from New Orleans to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $269 to $1,698. That means the highest observed fare was about 6x higher than the lowest one.

  • Which airlines offer Wi-Fi on New Orleans to Knoxville flights?

    Two airlines offer in-flight Wi-Fi on New Orleans to Knoxville flights:

    • American Airlines
    • JetBlue

    Pricing varies by airline and fare class. Some plans are included with the ticket or loyalty program; others are paid add-ons priced by flight length.

  • How are flight prices from New Orleans to Knoxville looking right now?

    One-way fares from New Orleans to Knoxville are currently lower than usual. Average one-way flight prices are about $237, which is 5% below the typical average for this route.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $82 for economy cars. Top options include:

    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Thrifty
    • Avis

  • Which airports can I use when flying from New Orleans to Knoxville?

    Flights from New Orleans to Knoxville usually depart from New Orleans Louis Armstrong (MSY) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airports do connecting flights from New Orleans to Knoxville pass through?

    One-stop flights from New Orleans to Knoxville most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 59% of one-stop connections
    • Nashville Intl (BNA) - 20% of one-stop connections
    • Charlotte Douglas (CLT) - 6% of one-stop connections
    • Dallas/Fort Worth (DFW) - 6% of one-stop connections

  • Can I save money by using flexible dates for flights from New Orleans to Knoxville?

    Yes. Flexible dates can save you up to 33% on flights from New Orleans to Knoxville. Thursday is the cheapest departure day at $354 round-trip on average, while Sunday is the most expensive at $521, a difference of $167.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from New Orleans to Knoxville?

    2 airlines operate flights between New Orleans and Knoxville. The airlines offering nonstop flights on this route include:

    • Southwest
    • American Airlines

  • How much time can I save by choosing a different layover airport from New Orleans to Knoxville?

    Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 58m, compared with 4h 06m via Atlanta Hartsfield-Jackson (ATL) and 4h 50m via Charlotte Douglas (CLT).

  • What is the time difference between New Orleans and Knoxville?

    Knoxville is 1 hour ahead of New Orleans (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which airlines offer extra legroom and free seat selection on New Orleans to Knoxville flights?

    Among airlines operating New Orleans to Knoxville flights:

    • American Airlines: offers free seat selection
    • Southwest: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on New Orleans to Knoxville flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • American Airlines: a cabin bag in Economy Class class
    • JetBlue: a cabin bag in Economy Class class
    • Southwest: a cabin bag in Economy Class class

    Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.

Your guide to booking New Orleans to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Sunday. On this route, Thursday flights average $354, about $167 less than Sunday fares (32% savings) based on the last 12 months.
  • If you can choose when to travel, plan your New Orleans to Knoxville trip for October. Fares historically average $329 round-trip in that month - typically $361 less than the most expensive month, which is March (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Orlando Airport (MCO) can be cheaper than flying direct. The cheapest layover option averages $329 round-trip on this route - about $457 less than direct flights (based on the last 12 months).

More options for your flight from New Orleans to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental