MSY - TYS

$96 Find Cheap Flights from New Orleans to Knoxville - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$191
Typical prices: $346-$510
American Airlines
Sat 11/3Wed 11/7
MSY - TYS • 1 stop
Cheapest one-way
$96
Typical prices: $158-$323
Southwest
Wed 10/24
MSY - TYS • 1 stop
Nonstop flights
There are currently no direct flights between New Orleans and Knoxville. You'll need to take a connecting flight to reach the destination.
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When to book
in advance
Our data shows that travelers who book at least 23 weeks in advance save around 52% compared to booking last minute.
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Insights
When to travel
Cheapest • 9% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $329 (round-trip)
Shortest trip • 3h 59m (one-way)
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We hope you love your trip to Knoxville!
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Flight Deals

Cheap Flights from New Orleans to Knoxville (MSY-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from New Orleans to Knoxville

Tue, Nov 3 - Sat, Nov 7
American Airlines Logo
3:45 pm - 11:32 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 47m1 stop Dallas/Fort Worth
American Airlines Logo
5:32 pm - 10:57 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 25m1 stop Dallas/Fort Worth
$191American Airlines
Wed, Jan 6 - Sat, Jan 9
Southwest Logo
7:30 am - 2:00 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 30m1 stop Dallas Love Field
Southwest Logo
2:15 pm - 7:25 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 10m1 stop Nashville Intl
$192Southwest
Wed, Jan 6 - Sat, Jan 9
Southwest Logo
7:30 am - 2:00 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 30m1 stop Dallas Love Field
Southwest Logo
6:55 am - 2:20 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
8h 25m2 stops Nashville Intl Dallas Love Field
$198Southwest
Wed, Nov 11 - Mon, Nov 16
Southwest Logo
9:30 am - 4:40 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 10m1 stop Orlando
Southwest Logo
1:00 pm - 5:35 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 35m1 stop Orlando
$203Southwest
Fri, Dec 11 - Mon, Dec 14
Delta Logo
6:21 pm - 11:57 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
4h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:28 pm - 12:07 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 39m1 stop Atlanta Hartsfield-Jackson
$247Delta
Tue, Nov 3 - Sat, Nov 7
American Airlines Logo
5:39 am - 12:12 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 33m1 stop Dallas/Fort Worth
American Airlines Logo
5:32 pm - 10:57 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 25m1 stop Dallas/Fort Worth
$271American Airlines
Fri, Oct 16 - Fri, Oct 23
Multiple Airlines Logo
5:05 pm - 5:21 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
47h 16m2 stops Atlanta Hartsfield-Jackson Washington, D.C. Dulles Intl
Multiple Airlines Logo
8:00 am - 8:10 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
13h 10m1 stop Orlando
$279Multiple Airlines
Wed, Nov 18 - Sun, Nov 22
American Airlines Logo
5:39 am - 2:05 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
7h 26m1 stop Dallas/Fort Worth
American Airlines Logo
5:30 am - 10:05 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 35m1 stop Dallas/Fort Worth
$279American Airlines
Sat, Oct 24 - Mon, Oct 26
Multiple Airlines Logo
8:00 am - 8:50 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
11h 50m1 stop Orlando
Multiple Airlines Logo
5:44 pm - 4:13 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
23h 29m2 stops Orlando Sanford Intl Atlanta Hartsfield-Jackson
$281Multiple Airlines
Fri, Dec 11 - Mon, Dec 14
Delta Logo
6:21 pm - 11:57 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
4h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:28 pm - 12:07 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 39m1 stop Atlanta Hartsfield-Jackson
$291Delta
Booking Insights

Price, demand and travel trends for New Orleans to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from New Orleans to Knoxville with more confidence.

How much is a round-trip flight from New Orleans to Knoxville?

Round-trip flights from New Orleans to Knoxville start at $191. Prices are below average for this route right now, with typical round-trip fares ranging from $346 to $510. The lowest price found in the past 5 days was $191 on American Airlines.

What's the cheapest day of the week to fly from New Orleans to Knoxville?

Thursday is the cheapest day of the week to fly from New Orleans to Knoxville, it is 15% cheaper than the average day. Sunday is the most expensive day with flight prices 14% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from New Orleans to Knoxville?

•November is the cheapest month to fly from New Orleans to Knoxville at $377 round-trip.
•July ($636) and January ($607) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 68% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from New Orleans to Knoxville the cheapest?

Flights from New Orleans to Knoxville are cheapest 23 weeks before departure. Booking in this window typically costs about 52% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for New Orleans to Knoxville flights

Low season

February

Cheapest flight

$96
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from New Orleans to Knoxville

When to book flights from New Orleans to Knoxville

Are your dates flexible? Find out the best times to travel from New Orleans to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your New Orleans to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airlines offer extra legroom and free seat selection on New Orleans to Knoxville flights?

    Among airlines operating New Orleans to Knoxville flights:

    • American Airlines: offers free seat selection
    • Southwest: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • What airlines are available from New Orleans to Knoxville?

    2 airlines operate flights between New Orleans and Knoxville. The airlines offering nonstop flights on this route include:

    • Southwest
    • American Airlines

  • Which airports can I use when flying from New Orleans to Knoxville?

    Flights from New Orleans to Knoxville usually depart from New Orleans Louis Armstrong (MSY) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airlines include bags at no extra cost on New Orleans to Knoxville flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • American Airlines: a cabin bag in Economy Class class
    • Southwest: a cabin bag in Economy Class class

    Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

  • What cabin classes can I book on flights from New Orleans to Knoxville?

    Only Economy Class is available on flights from New Orleans to Knoxville.

  • What is the standard checked-bag allowance on flights from New Orleans to Knoxville?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $50–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from New Orleans to Knoxville?

    The Embraer 175 family is used most often on this route, operated mainly by American Airlines. Other aircraft seen on the route include Boeing 737 MAX 8 variants.

  • Which airports do connecting flights from New Orleans to Knoxville pass through?

    One-stop flights from New Orleans to Knoxville most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 61% of one-stop connections
    • Nashville Intl (BNA) - 17% of one-stop connections
    • Charlotte Douglas (CLT) - 9% of one-stop connections
    • Dallas/Fort Worth (DFW) - 4% of one-stop connections

    Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from New Orleans to Knoxville?

    Yes. Being flexible with your travel dates can save you up to 26% on the New Orleans to Knoxville route. Thursday is the cheapest departure day at $356 round-trip on average, while Sunday is the most expensive at $477, a difference of $121. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What are the earliest and latest flights from New Orleans to Knoxville?

    These are the earliest and latest flight times available from New Orleans to Knoxville:

    • Earliest: departs at 8:05 am and lands at 10:05 am
    • Latest: departs at 2:30 pm and lands at 4:30 pm.

    The flight takes about 2h 00m.

  • How expensive are last-minute New Orleans to Knoxville flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 35% above the route average of $415. Book 23 weeks before departure for the lowest fares.

  • How long is a flight from New Orleans to Knoxville?

    A nonstop flight from New Orleans to Knoxville takes 2h 00m, covering 541 miles.

  • Do I need a passport to fly from New Orleans to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from New Orleans to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $203 to $927. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from New Orleans to Knoxville looking right now?

    One-way fares from New Orleans to Knoxville are currently lower than usual. Average one-way flight prices are about $109, which is 56% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from New Orleans to Knoxville?

    Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 59m, compared with 4h 00m via Atlanta Hartsfield-Jackson (ATL) and 4h 22m via Charlotte Douglas (CLT).

  • What is the time difference between New Orleans and Knoxville?

    Knoxville is 1 hour ahead of New Orleans (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Payless

  • How much should I expect to pay for a New Orleans to Knoxville flight?

    Round-trip flights from New Orleans to Knoxville range from $346 to $510, with an average of $415 over the past 12 months. Anything below $346 counts as a good deal.

  • Which airlines offer Wi-Fi on New Orleans to Knoxville flights?

    American Airlines is the only airline on the New Orleans to Knoxville route offering in-flight Wi-Fi. Pricing depends on fare class.

Your guide to booking New Orleans to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Sunday. On this route, Thursday flights average $356 - about $121 less than Sunday (25% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 23 weeks before you fly. On this route, that window historically saves about 52% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your New Orleans to Knoxville trip for November. Fares historically average $377 round-trip in that month - typically $259 less than the most expensive month, which is July (based on the last 12 months).

Prefer to fly direct from New Orleans to Knoxville?

 
Find which airlines fly direct from New Orleans Louis Armstrong Airport to Knoxville McGhee Tyson Airport, which days they fly and book direct flights.

Direct departures

New Orleans Louis Armstrong to Knoxville McGhee Tyson

Friday

American Airlines,Southwest

American Airlines,Southwest

See more direct flights

Direct returns

Knoxville McGhee Tyson to New Orleans Louis Armstrong

Sunday

American Airlines,Southwest

American Airlines,Southwest

See more direct flights

More options for your flight from New Orleans to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental