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$226 Find Cheap Flights from Orange County to Key West - Compare and Save

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Cheap Flights from Orange County to Key West

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Orange County to Key West

Tue, Jan 5 - Sat, Jan 9
American Airlines Logo
7:15 am - 6:46 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
8h 31m1 stop Charlotte Douglas
American Airlines Logo
2:40 pm - 7:52 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
8h 12m1 stop Dallas/Fort Worth
$439American Airlines
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
6:45 am - 4:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 10m1 stop Dallas/Fort Worth
American Airlines Logo
3:41 pm - 10:32 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 51m1 stop Charlotte Douglas
$488American Airlines
Sat, Jan 30 - Tue, Feb 2
Delta Logo
6:45 am - 7:43 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 12:56 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
8h 56m1 stop Atlanta Hartsfield-Jackson
$489Delta
Tue, Feb 2 - Sat, Feb 6
Delta Logo
6:45 am - 7:43 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 12:56 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
8h 56m1 stop Atlanta Hartsfield-Jackson
$489Delta
Sat, Jan 30 - Sat, Feb 6
Delta Logo
6:45 am - 7:43 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 12:56 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
8h 56m1 stop Atlanta Hartsfield-Jackson
$489Delta
Tue, Jan 5 - Sat, Jan 9
American Airlines Logo
1:18 pm - 9:22 amSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
17h 04m2 stops Phoenix Sky Harbor Intl Miami
American Airlines Logo
2:40 pm - 7:52 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
8h 12m1 stop Dallas/Fort Worth
$529American Airlines
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
6:45 am - 4:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 10m1 stop Dallas/Fort Worth
American Airlines Logo
11:14 am - 10:32 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
14h 18m2 stops Miami Charlotte Douglas
$588American Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
7:25 am - 2:08 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
27h 43m2 stops San Francisco Newark
United Airlines Logo
3:55 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Chicago O'Hare Intl
$682United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
7:25 am - 2:08 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
27h 43m2 stops San Francisco Newark
United Airlines Logo
3:55 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Chicago O'Hare Intl
$712United Airlines
Fri, Jan 29 - Wed, Feb 3
United Airlines Logo
1:20 pm - 2:08 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
21h 48m2 stops Denver Intl Newark
United Airlines Logo
3:55 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Chicago O'Hare Intl
$720United Airlines
Useful Info

Good to know

Low season

September

Cheapest flight

$226
Best time to beat the crowds but there is an average 5% increase in price.
Flight from John Wayne (Santa Ana) to Key West

FAQs for booking flights from Orange County to Key West

  • How does KAYAK find such low prices on flights from Orange County to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Orange County to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Orange County to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from Orange County is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Orange County to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to Orange County with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Orange County to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from Orange County up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Orange County to Key West

 
Need help choosing which airline to fly with from Orange County to Key West? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8557 reviews
8.5Crew
7.2Food
7.8Entertainment
7.8Comfort
8.1Boarding
Airline reviews

The actual flight was smooth and we arrived earlier than expected which was great. The flight attendants gave unclear instructions and were rude. They seemed overwhelmed or flustered for the flight. Inflight service was delayed and unsure why.

6.0 GoodCynthia, Aug 2026
Read more Delta reviews

The actual flight was smooth and we arrived earlier than expected which was great. The flight attendants gave unclear instructions and were rude. They seemed overwhelmed or flustered for the flight. Inflight service was delayed and unsure why.

There needs to be better accommodations for waiting passengers. A a designated standing space that is separated and away from concourse traffic.

overall the crew onboarding and providing service during our flight was great; they were friendly and helpful. I said ok to the entertainment because there was none, but the crew explained why which was very helpful. I am a diabetic and the type of snacks are not diabetic friendly (full of carbs and sugar). However, I am always prepared because I know the catering is for the larger population.

We were skipped when the snack cart passed and then the attendant said we weren’t . I am disabled and was in a row toward the back of the plane which was very difficult for me to navigate. Disabled people should not be forced to walk the plank.

Flight was delayed and then "they did not have time to load food". No snack or drink at all for 1.5 how flight. Somebody wasn't prepared.

N Everything was perfect from boarding to assistance to baggage in Tampa

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Gate 461 the worst in LAX Boarding lacks professionalism And as usual, your food sucks.

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

The flight was really crowded. Flight attendants were just ok.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

It was the worst experience ever. Cabin temperature cold, for which they did not have any blankets upon my asking. We paid $125 extra for each passenger to get extra space sits; the sits were ridiculously small, tight, and uncomfortable! The flight attendant dropped ice on me and my sister! All in all, American Airlines deserves below zero!

The inability to be flexible when you need to change a Basic Economy flight, when your company demands you book through a third party, causes raw feelings about the whole experience. A major airline should realize business and personal plans change all the time. I must save my company money on travel. Even if you have to charge me for the change, I get it. But being so rigid with a policy is not the best customer service.

We sat on the plane for 1 hour because the airline was short handed could not be unloading.

We are gluten free, there were not any available complimentary gluten free options.

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

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