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Cheap Flights from Orange County to Key West

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Orange County to Key West

Wed, Jan 6 - Wed, Jan 13
Delta Logo
6:45 am - 7:43 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 5:59 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
13h 59m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl
$464Delta
Wed, Jan 6 - Wed, Jan 13
American Airlines Logo
6:45 am - 4:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 07m1 stop Dallas/Fort Worth
American Airlines Logo
3:41 pm - 10:09 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 28m1 stop Charlotte Douglas
$508American Airlines
Wed, Jan 13 - Sat, Jan 16
American Airlines Logo
6:45 am - 4:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 07m1 stop Dallas/Fort Worth
American Airlines Logo
1:52 pm - 10:09 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 17m1 stop Charlotte Douglas
$508American Airlines
Sat, Sep 26 - Wed, Sep 30
Delta Logo
6:45 am - 8:00 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
10h 15m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 6:29 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
7h 29m1 stop Atlanta Hartsfield-Jackson
$575Delta
Sat, Sep 26 - Wed, Sep 30
Delta Logo
7:12 am - 8:00 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 48m2 stops Salt Lake City Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 6:29 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
7h 29m1 stop Atlanta Hartsfield-Jackson
$580Delta
Wed, Jan 13 - Sat, Jan 16
American Airlines Logo
7:47 pm - 9:22 amSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
10h 35m2 stops Phoenix Sky Harbor Intl Miami
American Airlines Logo
1:52 pm - 10:09 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 17m1 stop Charlotte Douglas
$581American Airlines
Sat, Sep 26 - Wed, Sep 30
Delta Logo
7:12 am - 8:00 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 48m2 stops Salt Lake City Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 30m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl
$585Delta
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
2:38 pm - 2:08 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
20h 30m2 stops San Francisco Newark
United Airlines Logo
3:55 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Chicago O'Hare Intl
$672United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
6:45 am - 2:08 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
28h 23m3 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl Newark
United Airlines Logo
3:55 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Chicago O'Hare Intl
$763United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
10:25 am - 12:15 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
22h 50m1 stop Chicago O'Hare Intl
United Airlines Logo
3:55 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Chicago O'Hare Intl
$766United Airlines
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Good to know

Low season

September

Cheapest flight

$315
Best time to beat the crowds but there is an average 6% increase in price.
Flight from John Wayne (Santa Ana) to Key West

FAQs for booking flights from Orange County to Key West

  • How does KAYAK find such low prices on flights from Orange County to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Orange County to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Orange County to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from Orange County is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Orange County to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to Orange County with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Orange County to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from Orange County up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Orange County to Key West

 
Need help choosing which airline to fly with from Orange County to Key West? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8564 reviews
7.8Entertainment
7.2Food
7.8Comfort
8.1Boarding
8.5Crew
Airline reviews

Flight Staff: Always great! Checking back vs carry-on: I typically check my bag since so much time is spent stowing the bag, it's heavy, maybe not enough room. Delta is charging $45 to check bags. Yet, the people who have multiple carry-on bags are then asked to check their bags and are offered this service for free. This does not seem fair to a person who is trying to be proactive in improving the process . Boarding: Boarding is always slow and exhausting. With the exception of First Class, Economy, why not board the zone in the back of the plane first??? Seats: Why cross the seat belts? I get that it looks nice, but people waste so much time moving them or sitting on them and then having to move. Seats: On both my flights the seat did not recline. Not a big deal. Smell: There was a horrific smell like the restrooms on my first flight. I thought I was going to be sick. Most flights do not smell great. Does Delta use air purifiers or anything?

6.0 GoodPaula, Sep 2026
Read more Delta reviews

Flight Staff: Always great! Checking back vs carry-on: I typically check my bag since so much time is spent stowing the bag, it's heavy, maybe not enough room. Delta is charging $45 to check bags. Yet, the people who have multiple carry-on bags are then asked to check their bags and are offered this service for free. This does not seem fair to a person who is trying to be proactive in improving the process . Boarding: Boarding is always slow and exhausting. With the exception of First Class, Economy, why not board the zone in the back of the plane first??? Seats: Why cross the seat belts? I get that it looks nice, but people waste so much time moving them or sitting on them and then having to move. Seats: On both my flights the seat did not recline. Not a big deal. Smell: There was a horrific smell like the restrooms on my first flight. I thought I was going to be sick. Most flights do not smell great. Does Delta use air purifiers or anything?

DL482 did not wait for about 10 of us including a mother and 3 children when we were in the same terminal on DL486, where we were switching from waiting for a jet bridge fix, to moving to a neighboring gate. I understand taxiing delays are ok either but man. We only needed 5 more minutes. DL482 did not adjust from their times at all. This was my first time with Delta.

The actual flight was smooth and we arrived earlier than expected which was great. The flight attendants gave unclear instructions and were rude. They seemed overwhelmed or flustered for the flight. Inflight service was delayed and unsure why.

There needs to be better accommodations for waiting passengers. A a designated standing space that is separated and away from concourse traffic.

overall the crew onboarding and providing service during our flight was great; they were friendly and helpful. I said ok to the entertainment because there was none, but the crew explained why which was very helpful. I am a diabetic and the type of snacks are not diabetic friendly (full of carbs and sugar). However, I am always prepared because I know the catering is for the larger population.

N Everything was perfect from boarding to assistance to baggage in Tampa

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Gate 461 the worst in LAX Boarding lacks professionalism And as usual, your food sucks.

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

The flight was really crowded. Flight attendants were just ok.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

It was the worst experience ever. Cabin temperature cold, for which they did not have any blankets upon my asking. We paid $125 extra for each passenger to get extra space sits; the sits were ridiculously small, tight, and uncomfortable! The flight attendant dropped ice on me and my sister! All in all, American Airlines deserves below zero!

The inability to be flexible when you need to change a Basic Economy flight, when your company demands you book through a third party, causes raw feelings about the whole experience. A major airline should realize business and personal plans change all the time. I must save my company money on travel. Even if you have to charge me for the change, I get it. But being so rigid with a policy is not the best customer service.

We sat on the plane for 1 hour because the airline was short handed could not be unloading.

We are gluten free, there were not any available complimentary gluten free options.

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

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