SNA - EYW

$389 Find Cheap Flights from Santa Ana to Key West

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Key West departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Key West

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Key West, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Key West, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$389
Spirit Airlines
Sat 4/4Mon 4/13
SNA - EYW • 2 stops
Cheapest one-way
$410
Delta
Tue 6/30
SNA - EYW • 1 stop
Top airlines
Spirit Airlines
Cheapest • from $389 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Key West. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Chicago (ORD)
Cheapest • Avg $636 (round-trip)
Dallas (DFW)
Shortest trip • 6h 32m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Key West!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Key West (SNA-EYW)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Key West that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Key West

Sat, Apr 4 - Mon, Apr 13
Spirit Airlines Logo
10:48 am - 11:30 am
SNA
-
EYW
21h 42m
2 stops
Spirit Airlines Logo
2:35 pm - 9:53 am
EYW
-
SNA
22h 18m
2 stops
$389Spirit Airlines
Sat, Apr 4 - Mon, Apr 13
Spirit Airlines Logo
6:45 am - 11:30 am
SNA
-
EYW
25h 45m
3 stops
Spirit Airlines Logo
2:35 pm - 9:53 am
EYW
-
SNA
22h 18m
2 stops
$416Spirit Airlines
Sat, Apr 4 - Mon, Apr 13
Spirit Airlines Logo
2:53 pm - 11:30 am
SNA
-
EYW
17h 37m
3 stops
Spirit Airlines Logo
2:35 pm - 9:13 pm
EYW
-
SNA
33h 38m
3 stops
$461Spirit Airlines
Sat, Apr 4 - Tue, Apr 14
Spirit Airlines Logo
2:53 pm - 11:30 am
SNA
-
EYW
17h 37m
3 stops
Spirit Airlines Logo
12:25 pm - 9:45 pm
EYW
-
SNA
36h 20m
3 stops
$500Spirit Airlines
Sat, Apr 4 - Tue, Apr 14
Spirit Airlines Logo
2:53 pm - 11:30 am
SNA
-
EYW
17h 37m
2 stops
Spirit Airlines Logo
12:25 pm - 9:45 pm
EYW
-
SNA
36h 20m
3 stops
$518Spirit Airlines
Wed, Apr 1 - Sun, Apr 5
Spirit Airlines Logo
2:53 pm - 11:30 am
SNA
-
EYW
17h 37m
2 stops
Spirit Airlines Logo
12:25 pm - 9:53 am
EYW
-
SNA
24h 28m
2 stops
$581Spirit Airlines
Fri, May 1 - Tue, May 5
American Airlines Logo
6:45 am - 10:36 pm
SNA
-
EYW
12h 51m
2 stops
American Airlines Logo
2:29 pm - 8:50 pm
EYW
-
SNA
9h 21m
1 stop
$591American Airlines
Fri, May 1 - Tue, May 5
American Airlines Logo
6:45 am - 10:36 pm
SNA
-
EYW
12h 51m
2 stops
American Airlines Logo
11:24 am - 9:14 pm
EYW
-
SNA
12h 50m
2 stops
$597American Airlines
Wed, Apr 1 - Sun, Apr 5
Spirit Airlines Logo
10:48 am - 11:30 am
SNA
-
EYW
21h 42m
3 stops
Spirit Airlines Logo
12:25 pm - 9:53 am
EYW
-
SNA
24h 28m
2 stops
$601Spirit Airlines
Thu, Jun 4 - Tue, Jun 9
Multiple Airlines Logo
3:34 pm - 9:14 am
SNA
-
EYW
14h 40m
1 stop
Multiple Airlines Logo
1:14 pm - 2:28 pm
EYW
-
SNA
28h 14m
2 stops
$612Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Key West flights

Get data-powered insights and trends into flights from Santa Ana to Key West to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Key West?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Key West were found on Spirit Airlines ($389) and American Airlines ($509).

Find deals

Good to know

Low seasonApril
Cheapest flight$389
Best time to beat the crowds with an average 44% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from John Wayne (Santa Ana) to Key West

When to book flights from Santa Ana to Key West

Are your dates flexible? Find out the best times to travel from Santa Ana to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Key West

  • What is the cheapest flight from Santa Ana to Key West?

    In the last 3 days, the lowest price for a flight from Santa Ana to Key West was $410 for a one-way ticket and $389 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Key West?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from John Wayne (Santa Ana) to Key West?

    When flying out of John Wayne (Santa Ana) you will be using Santa Ana J. Wayne/Orange Cnty. You will be landing at Key West, also known as Key West.

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Key West?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Key West?

    oneworld is the only airline alliance operating flights between John Wayne (Santa Ana) and Key West.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and EYW can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Key West

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Key West. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Key West? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11468 reviews
7.2Comfort
7.5Boarding
6.4Food
7.9Crew
6.9Entertainment
Airline reviews

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

6.0 GoodAnna, Mar 2026
DFW - MIA
Read more American Airlines reviews

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Mechanical issue delayed us 2hrs and then once we landed sat on tarmac for 30mins because someone left a vehicle in front of the gaye

Plane from partner PSA was filthy. Plastic needs to be thoroughly cleaned. Really disgusting to look at and wonder about cleanliness of parts less visible.

Flight delay for mechanical. Inbound arrived on time. No one said why mechanical delay.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

The flight was really crowded. Flight attendants were just ok.

Didn't get a seat assignment until the last minute even though i picked a seat.

Everything you need to know for your flight from Santa Ana to Key West

Information on your arrival and departure airports

John Wayne (Santa Ana) (SNA)
Key West (EYW)