SNA - EYW

$151 Find Cheap Flights from John Wayne (Santa Ana) to Key West - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$479
Typical prices: $532-$841
American Airlines
Wed 12/5Sun 12/9
SNA - EYW • 1 stop
Cheapest one-way
$151
Typical prices: $430-$637
Multiple Airlines
Thu 1/18
SNA - EYW • 3 stops
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Key West. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
November
Cheapest • 50% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago O'Hare Intl (ORD)
Cheapest • Avg $636 (round-trip)
Dallas/Fort Worth (DFW)
Shortest trip • 7h 59m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Santa Ana to Key West (SNA-EYW)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Key West

Sat, Dec 5 - Wed, Dec 9
American Airlines Logo
6:45 am - 4:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 07m1 stop Dallas/Fort Worth
American Airlines Logo
1:52 pm - 10:17 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 25m1 stop Charlotte Douglas
$479American Airlines
Wed, Jan 13 - Fri, Jan 22
American Airlines Logo
6:45 am - 4:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 07m1 stop Dallas/Fort Worth
American Airlines Logo
1:52 pm - 10:12 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 20m1 stop Charlotte Douglas
$532American Airlines
Wed, Apr 28 - Mon, May 3
American Airlines Logo
6:45 am - 5:02 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 17m1 stop Dallas/Fort Worth
American Airlines Logo
2:01 pm - 9:14 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
10h 13m1 stop Charlotte Douglas
$532American Airlines
Sat, Dec 5 - Wed, Dec 9
American Airlines Logo
6:45 am - 4:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 07m1 stop Dallas/Fort Worth
American Airlines Logo
6:35 pm - 9:02 amEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
17h 27m2 stops Miami Phoenix Sky Harbor Intl
$562American Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
7:15 am - 2:13 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
27h 58m2 stops San Francisco Newark
United Airlines Logo
4:09 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 21m1 stop Chicago O'Hare Intl
$702United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
7:15 am - 2:13 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
27h 58m2 stops San Francisco Newark
United Airlines Logo
4:09 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 21m1 stop Chicago O'Hare Intl
$712United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
6:45 am - 3:22 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
29h 37m1 stop Chicago O'Hare Intl
United Airlines Logo
4:09 pm - 10:30 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 21m1 stop Chicago O'Hare Intl
$832United Airlines
Thu, Nov 26 - Thu, Dec 3
Delta Logo
6:45 am - 5:10 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 25m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:25 am - 1:20 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
8h 55m1 stop Atlanta Hartsfield-Jackson
$840Delta
Tue, Nov 10 - Sat, Nov 14
Delta Logo
6:45 am - 5:10 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
7h 25m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:30 am - 4:22 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 52m2 stops Atlanta Hartsfield-Jackson Salt Lake City
$877Delta
Tue, Nov 10 - Sat, Nov 14
Delta Logo
7:15 am - 8:00 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
9h 45m2 stops Salt Lake City Atlanta Hartsfield-Jackson
Delta Logo
7:30 am - 4:22 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
11h 52m2 stops Atlanta Hartsfield-Jackson Salt Lake City
$882Delta
Booking Insights

Price, demand and travel trends for Santa Ana to Key West flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santa Ana to Key West?

Round-trip flights from Santa Ana to Key West typically range from $532 to $841. The lowest price found in the past 5 days was $479, on American Airlines.

What's the cheapest day of the week to fly from Santa Ana to Key West?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santa Ana to Key West. It’s 35% cheaper than the average day, while Monday is the most expensive, with prices 38% higher.

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Key details for Santa Ana to Key West flights

Low season

April

Cheapest flight

$151
Beat the crowds with an average 51% drop in travelers.
The most popular month to fly with an average 59% increase in travelers.
One-way flight from Santa Ana to Key West

When to book flights from Santa Ana to Key West

Are your dates flexible? Find out the best times to travel from Santa Ana to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Ana to Key West flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santa Ana to Key West?

    Only Economy Class is available on flights from Santa Ana to Key West.

  • How long is a flight from Santa Ana to Key West?

    A nonstop flight from Santa Ana to Key West takes 00m, covering 2,254 miles.

  • Do I need a passport to fly from Santa Ana to Key West?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Santa Ana to Key West flight?

    Round-trip flights from Santa Ana to Key West range from $532 to $841, with an average of $697 over the past 12 months. Anything below $532 counts as a good deal.

  • How are flight prices from Santa Ana to Key West looking right now?

    One-way fares from Santa Ana to Key West are currently lower than usual. Average one-way flight prices are about $263, which is 53% below the typical average for this route.

  • What car rental options are available at Key West Airport (EYW)?

    Key West Airport (EYW) hosts 5 major car rental companies, with daily rates averaging $67 for economy cars. Top options include:

    • Dollar
    • Hertz
    • Budget
    • Enterprise Rent-A-Car
    • Alamo

  • Which airports can I use when flying from Santa Ana to Key West?

    Flights from Santa Ana to Key West usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Key West (EYW).

  • Which airports do connecting flights from Santa Ana to Key West pass through?

    One-stop flights from Santa Ana to Key West most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 55% of one-stop connections
    • Charlotte Douglas (CLT) - 25% of one-stop connections
    • Dallas/Fort Worth (DFW) - 15% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Santa Ana to Key West?

    Yes. Flexible dates can save you up to 53% on flights from Santa Ana to Key West. Wednesday is the cheapest departure day at $459 round-trip on average, while Monday is the most expensive at $968, a difference of $509.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santa Ana to Key West?

    Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 7h 59m, compared with 8h 43m via Charlotte Douglas (CLT) and 8h 56m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Santa Ana and Key West?

    Key West is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Key West?

    Some of the most popular sights in Key West are Duval Street, Key West Historic District and Mallory Square. These are among the most viewed places in Key West on KAYAK.

Your guide to booking Santa Ana to Key West flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $459, about $509 less than Monday fares (53% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Ana to Key West trip for November. Fares historically average $348 round-trip in that month - typically $1,205 less than the most expensive month, which is September (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Key West Airport.

    • Parrot Key Hotel & Villas
    • Margaritaville Beach House Key West
    • Havana Cabana at Key West

More options for your flight from Santa Ana to Key West

Complete your trip to Key West with a hotel stay or car rental

Car rentals in Key West
Hotels in Key West
Vacations in Key West