SNA - EYW

$389 Find Cheap Flights from John Wayne (Santa Ana) to Key West - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Key West departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$389
American Airlines
Sun 11/1Sat 11/7
SNA - EYW • 1 stop
Top airlines
Cheapest • from $389 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Key West. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $636 (round-trip)
Shortest trip • 6h 42m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Key West!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Key West (SNA-EYW)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Key West that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Key West

Sun, Nov 1 - Sat, Nov 7
American Airlines Logo
7:45 am - 6:45 pm
SNA
-
EYW
8h 00m
1 stop
American Airlines Logo
2:26 pm - 7:10 pm
EYW
-
SNA
7h 44m
1 stop
$389American Airlines
Sat, Sep 5 - Wed, Sep 9
Delta Logo
6:45 am - 7:57 pm
SNA
-
EYW
10h 12m
1 stop
Delta Logo
7:40 am - 12:33 pm
EYW
-
SNA
7h 53m
1 stop
$444Delta
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
6:45 am - 4:55 pm
SNA
-
EYW
7h 10m
1 stop
American Airlines Logo
2:26 pm - 7:10 pm
EYW
-
SNA
7h 44m
1 stop
$472American Airlines
Wed, Aug 12 - Sun, Aug 16
Breeze Airways Logo
1:10 pm - 11:25 am
SNA
-
EYW
19h 15m
1 stop
Breeze Airways Logo
12:05 pm - 12:11 pm
EYW
-
SNA
27h 06m
2 stops
$475Breeze Airways
Wed, Aug 12 - Sun, Aug 16
Breeze Airways Logo
1:10 pm - 11:25 am
SNA
-
EYW
19h 15m
1 stop
Breeze Airways Logo
7:53 pm - 12:11 pm
EYW
-
SNA
19h 18m
2 stops
$490Breeze Airways
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
6:45 am - 4:55 pm
SNA
-
EYW
7h 10m
1 stop
American Airlines Logo
6:35 pm - 9:04 am
EYW
-
SNA
17h 29m
2 stops
$496American Airlines
Sat, Sep 5 - Wed, Sep 9
Delta Logo
7:00 am - 7:57 pm
SNA
-
EYW
9h 57m
2 stops
Delta Logo
7:40 am - 12:33 pm
EYW
-
SNA
7h 53m
1 stop
$504Delta
Sat, Aug 22 - Wed, Aug 26
Delta Logo
6:45 am - 7:57 pm
SNA
-
EYW
10h 12m
1 stop
Delta Logo
1:59 pm - 6:37 pm
EYW
-
SNA
7h 38m
1 stop
$527Delta
Sun, Nov 1 - Sat, Nov 7
American Airlines Logo
7:45 am - 6:45 pm
SNA
-
EYW
8h 00m
1 stop
American Airlines Logo
10:18 am - 5:42 pm
EYW
-
SNA
10h 24m
2 stops
$536American Airlines
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
6:30 pm - 3:29 pm
SNA
-
EYW
17h 59m
2 stops
United Airlines Logo
2:50 pm - 10:44 am
EYW
-
SNA
22h 54m
1 stop
$810United Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Key West flights

Get data-powered insights and trends into flights from Santa Ana to Key West to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from John Wayne (Santa Ana) to Key West?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Key West, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Key West is May, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $997 and $968 respectively.

Good to know

Low season

November

Cheapest flight

$389
Best time to beat the crowds with an average 49% drop in price.
Flight from John Wayne (Santa Ana) to Key West

When to book flights from Santa Ana to Key West

Are your dates flexible? Find out the best times to travel from Santa Ana to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Key West

  • What is the cheapest flight from John Wayne (Santa Ana) to Key West?

    In the last 5 days, the lowest price for a flight from John Wayne (Santa Ana) to Key West was $389 for a round-trip ticket.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Key West?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from John Wayne (Santa Ana) to Key West?

    When flying out of John Wayne (Santa Ana) you will be using Santa Ana J. Wayne/Orange Cnty. You will be landing at Key West, also known as Key West.

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Key West?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Key West?

    SkyTeam, and oneworld are the airline alliances operating flights between John Wayne (Santa Ana) and Key West, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from John Wayne (Santa Ana) to Key West, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from John Wayne (Santa Ana) to Key West are Delta and American Airlines. With an average price for the route of $723 and an overall rating of 7.8, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $684 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and EYW can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Key West

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Key West. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Key West? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8486 reviews
7.8Entertainment
8.1Boarding
8.5Crew
7.8Comfort
7.2Food
Airline reviews

Flight team was great and we even arrived ahead of plan!

10.0 ExcellentTony, Jul 2026
SNA - ATL
Read more Delta reviews

Flight team was great and we even arrived ahead of plan!

We were skipped when the snack cart passed and then the attendant said we weren’t . I am disabled and was in a row toward the back of the plane which was very difficult for me to navigate. Disabled people should not be forced to walk the plank.

N Everything was perfect from boarding to assistance to baggage in Tampa

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Flight and seats were great. Food service was average at best. The real main problem we had is that we got cheeseburgers for the kids but the plates was extremely hot. Like ridiculously hot and the stewardess never said anything. Luckily or unluckily my wife touched the plate and was able to deal with it before the kids got burned.

The WiFi didn’t work entire flight, couldn’t watch a movie. The recline button didn’t work

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

The flight was really crowded. Flight attendants were just ok.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

We sat on the plane for 1 hour because the airline was short handed could not be unloading.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

Everything you need to know for your flight from Santa Ana to Key West

Information on your arrival and departure airports