TYS

$145 Find Cheap Flights from Orange County to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Orange County to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Orange County to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Orange County to Knoxville

Sat, May 2 - Wed, May 6
Multiple Airlines Logo
12:10 pm - 3:33 pm
SNA
-
TYS
24h 23m
1 stop
Multiple Airlines Logo
11:26 am - 9:09 am
TYS
-
SNA
24h 43m
2 stops
$304Multiple Airlines
Sat, May 2 - Sat, May 9
Multiple Airlines Logo
12:10 pm - 3:33 pm
SNA
-
TYS
24h 23m
1 stop
Multiple Airlines Logo
1:59 pm - 10:08 pm
TYS
-
SNA
35h 09m
2 stops
$312Multiple Airlines
Fri, May 1 - Mon, May 4
Multiple Airlines Logo
7:56 pm - 6:03 pm
SNA
-
TYS
19h 07m
2 stops
Multiple Airlines Logo
1:43 pm - 10:08 pm
TYS
-
SNA
11h 25m
1 stop
$326Multiple Airlines
Sun, Aug 16 - Sun, Aug 30
Multiple Airlines Logo
1:50 pm - 11:27 pm
SNA
-
TYS
6h 37m
1 stop
Multiple Airlines Logo
7:00 am - 8:09 am
TYS
-
SNA
28h 09m
1 stop
$332Multiple Airlines
Sun, Aug 16 - Thu, Aug 27
Multiple Airlines Logo
1:50 pm - 11:27 pm
SNA
-
TYS
6h 37m
1 stop
Multiple Airlines Logo
7:00 am - 8:09 am
TYS
-
SNA
28h 09m
1 stop
$345Multiple Airlines
Tue, Aug 18 - Wed, Aug 26
Delta Logo
6:45 am - 6:17 pm
SNA
-
TYS
8h 32m
1 stop
Delta Logo
2:30 pm - 6:20 pm
TYS
-
SNA
6h 50m
1 stop
$349Delta
Tue, Apr 28 - Tue, May 5
United Airlines Logo
7:00 am - 7:56 pm
SNA
-
TYS
9h 56m
2 stops
United Airlines Logo
4:20 pm - 8:44 pm
TYS
-
SNA
7h 24m
1 stop
$354United Airlines
Tue, Apr 14 - Tue, Apr 21
Delta Logo
7:00 am - 8:06 pm
LGB
-
TYS
10h 06m
2 stops
Delta Logo
6:15 am - 11:57 am
TYS
-
LGB
8h 42m
2 stops
$487Delta
Sat, Apr 18 - Wed, Apr 22
Southwest Logo
9:35 am - 7:35 pm
LGB
-
TYS
7h 00m
1 stop
Southwest Logo
7:05 am - 2:25 pm
TYS
-
LGB
10h 20m
2 stops
$528Southwest
Sat, Apr 18 - Wed, Apr 22
Southwest Logo
9:35 am - 7:35 pm
LGB
-
TYS
7h 00m
1 stop
Southwest Logo
7:05 am - 1:10 pm
TYS
-
LGB
9h 05m
1 stop
$557Southwest
Useful Info

Good to know

Low seasonJanuary
Cheapest flight$145
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from John Wayne (Santa Ana) to Knoxville

FAQs for booking flights from Orange County to Knoxville

  • How does KAYAK find such low prices on flights from Orange County to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Orange County to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Orange County to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Orange County is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Orange County to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Orange County with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Orange County to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Orange County up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Orange County to Knoxville

 
Need help choosing which airline to fly with from Orange County to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8383 reviews
7.2Food
8.5Crew
8.1Boarding
7.8Entertainment
7.9Comfort
Airline reviews

N Everything was perfect from boarding to assistance to baggage in Tampa

10.0 ExcellentDeborah, Apr 2026
LAX - TPA
Read more Delta reviews

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I took seat 15A in anticipation of window seat, there is no window.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

It was perfect! I've never flown with United before, but I definitely will in the future

I had a cancelled flight because of technical issues going to my destination, and a delayed flight coming home. All told it wasn’t a total bust.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

We had excellent customer service despite the chaos at George Bush airport in Houston!

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

OK, we were delayed and had to de plane and reboard.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Complimentary light meal would be appreciated. But great flight crew service on all legs

Flight boarded from Gate 159B, the farthest gate in the LAX Bradley Terminal. While the flight operated on time, the first class cabin attendant made no recognition of my being an Advantage Executive Platinum member.

The flight itself was excellent but the gate attendant made me check my carryon since she said it was an inch too big. I’ve had no problems with this carryon on recent flights on Qantas, Delta, Austrian, Southwest Airlines even though the overhead bins are the same size. there were other carryons in the bins that also looked larger than mine and there was room left in the bins for more. When I picked up my carryon from baggage claim one of the wheels had broken off.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Not good. One of my luggage is missing. And until now they can’t find it

My 9:50AM flight was delayed to 3:40PM "due to incoming aircraft delay". No aircraft is "delayed" that long. Found out once we did board (after several changes in times) that the aircraft had a maintenance issue and we had to wait for another aircraft. Just tell us that. The aircraft we did get was old and the seats need to be updated. I have been traveling for several weeks with AA and you should refresh your entertainment content as frequent flyers have gone through most of your new content. I have Celiac and a shellfish allergy and continue to have struggles with meals on business and first class flights. Please keep this in mind. Sorry - was a long travel day yesterday and a bit cranky this morning with my experience comments. Still an AA fan.

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

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Everything you need to know for your flight to Knoxville

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