TYS

$145 Find Cheap Flights from Orange County to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$288
Overall average: $419
Multiple Airlines
Tue 4/7Thu 4/23
SNA - TYS • 2 stops
Cheapest one-way
$145
Typical prices: $245-$658
United Airlines
Wed 4/8
SNA - TYS • 1 stop
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Flight Deals
Useful Info
Flight Deals

Cheap Flights from Orange County to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Orange County to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Orange County to Knoxville

Tue, Apr 7 - Thu, Apr 23
Multiple Airlines Logo
2:53 pm - 10:36 am
SNA
-
TYS
16h 43m
2 stops
Multiple Airlines Logo
4:28 pm - 10:46 am
TYS
-
SNA
21h 18m
1 stop
$288Multiple Airlines
Wed, Apr 15 - Tue, Apr 21
American Airlines Logo
2:42 pm - 11:56 pm
SNA
-
TYS
6h 14m
1 stop
American Airlines Logo
6:00 am - 10:05 am
TYS
-
SNA
7h 05m
1 stop
$289American Airlines
Tue, Mar 3 - Wed, Mar 11
Multiple Airlines Logo
4:37 pm - 7:03 pm
SNA
-
TYS
23h 26m
1 stop
Multiple Airlines Logo
10:00 am - 3:42 pm
TYS
-
SNA
8h 42m
1 stop
$290Multiple Airlines
Tue, Mar 3 - Tue, Mar 10
Multiple Airlines Logo
1:20 pm - 7:03 pm
SNA
-
TYS
26h 43m
1 stop
Multiple Airlines Logo
9:00 am - 8:55 am
TYS
-
SNA
26h 55m
1 stop
$294Multiple Airlines
Tue, Apr 7 - Wed, Apr 22
United Airlines Logo
12:15 pm - 11:41 pm
SNA
-
TYS
8h 26m
1 stop
United Airlines Logo
9:00 am - 1:36 pm
TYS
-
SNA
7h 36m
1 stop
$308United Airlines
Tue, Apr 7 - Wed, Apr 22
United Airlines Logo
12:15 pm - 11:41 pm
SNA
-
TYS
8h 26m
1 stop
United Airlines Logo
9:00 am - 1:36 pm
TYS
-
SNA
7h 36m
1 stop
$309United Airlines
Thu, Apr 23 - Thu, Apr 30
Multiple Airlines Logo
8:20 pm - 10:51 pm
SNA
-
TYS
23h 31m
1 stop
Multiple Airlines Logo
4:28 pm - 8:50 am
TYS
-
SNA
19h 22m
2 stops
$311Multiple Airlines
Fri, Apr 17 - Wed, Apr 22
Southwest Logo
7:00 pm - 11:40 am
LGB
-
TYS
13h 40m
2 stops
Southwest Logo
2:55 pm - 8:00 pm
TYS
-
LGB
8h 05m
1 stop
$449Southwest
Fri, Apr 17 - Wed, Apr 22
Southwest Logo
7:00 pm - 11:40 am
LGB
-
TYS
13h 40m
2 stops
Southwest Logo
7:05 am - 2:25 pm
TYS
-
LGB
10h 20m
2 stops
$464Southwest
Sat, May 23 - Wed, May 27
Delta Logo
5:00 pm - 9:27 am
LGB
-
TYS
13h 27m
2 stops
Delta Logo
3:00 pm - 9:50 pm
TYS
-
LGB
9h 50m
2 stops
$754Delta
Useful Info

Good to know

Low seasonJanuary
Cheapest flight$145
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from John Wayne (Santa Ana) to Knoxville

FAQs for booking flights from Orange County to Knoxville

  • How does KAYAK find such low prices on flights from Orange County to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Orange County to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Orange County to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Orange County is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Orange County to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Orange County with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Orange County to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Orange County up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Orange County to Knoxville

 
Need help choosing which airline to fly with from Orange County to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8203 reviews
7.9Comfort
8.1Boarding
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

Smallest leg room I've ever had on a plane.

10.0 ExcellentRussell, Feb 2026
ATL - TYS
Read more Delta reviews

Smallest leg room I've ever had on a plane.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

The flight crew where really good. Better then the crew from BNE to SFO

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

left on time, reasonable boarding process arrived early luggage came out quickly

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

I boarded flight UA#1318 at Sacramento International Airport going back to Houston TX. The flight was scheduled at 5:10am. I was able to check in virtually using the United Airlines app. When I entered the airport, there was no one outside assisting with checked bags as it was for Delta Airlines. Immediately upon entering, there was a LONG, EXTREMELY LONG line to the kiosks to get boarding passes. I stand in line to get boarding passes then had to move to ANOTHER EXTREMELY LONG line to get my bags checked in. While standing in this line, we noticed an agent taking customers to 3 at a time to her station to check their bags in. Lucky for me, she called me back, checked my bags for me and I was on my way. I then encountered another long line at the TSA check and to avoid I ending up having to sign up for CLEAR to bypass it. So glad, I did.,...Both of my flights were great with no issues, butthe check in progress at Bush Airport was so much smoother. Check-in at SMF airport needs to be anaylzed and corrected. Do better United, I know you can....thanks

Flight was delayed for 2 hours, then last minute the change to on time. The satélite location is far and a nightmare to get to.

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

For a 5 1/2 hour flite i considered the "business class" to be subpar. The seats were just ok, no amenities, really nothing more than a long domestic flight. Frankly disappointed.

It would be nice to have some low carb options in the snacks.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

The pilot greased the landing and the crew was fantastic.

delayed due to weather. Could not communicate with family since the wifi was broken

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