ECP - BUF

$156 Find Cheap Flights from Panama City to Buffalo - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Buffalo departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$311
Delta
Thu 8/27Tue 9/1
ECP - BUF • 1 stop
Cheapest one-way
$156
Delta
Tue 12/8
ECP - BUF • 1 stop
Top airlines
Cheapest • from $311 (round-trip)
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Panama City and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $472 (round-trip)
Shortest trip • 4h 28m (one-way)
Insights
Insights
Insights
Insights
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We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Buffalo (ECP-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Buffalo

Thu, Aug 27 - Tue, Sep 1
Delta Logo
4:10 pm - 11:59 pm
ECP
-
BUF
6h 49m
1 stop
Delta Logo
6:05 am - 10:42 am
BUF
-
ECP
5h 37m
1 stop
$311Delta
Mon, Aug 10 - Thu, Aug 13
American Airlines Logo
1:15 pm - 7:07 pm
ECP
-
BUF
4h 52m
1 stop
American Airlines Logo
6:59 pm - 10:40 pm
BUF
-
ECP
4h 41m
1 stop
$337American Airlines
Thu, Aug 27 - Tue, Sep 1
United Airlines Logo
1:47 pm - 9:07 pm
ECP
-
BUF
6h 20m
1 stop
United Airlines Logo
6:55 am - 4:38 pm
BUF
-
ECP
10h 43m
2 stops
$350United Airlines
Fri, Aug 28 - Tue, Sep 1
Delta Logo
6:51 pm - 11:59 pm
ECP
-
BUF
4h 08m
1 stop
Delta Logo
6:05 am - 10:42 am
BUF
-
ECP
5h 37m
1 stop
$359Delta
Tue, Aug 25 - Sun, Aug 30
American Airlines Logo
11:42 am - 6:02 pm
ECP
-
BUF
5h 20m
1 stop
American Airlines Logo
5:22 am - 11:29 am
BUF
-
ECP
7h 07m
1 stop
$362American Airlines
Tue, Aug 25 - Sun, Aug 30
Southwest Logo
11:30 am - 9:40 pm
ECP
-
BUF
9h 10m
2 stops
Southwest Logo
12:20 pm - 4:20 pm
BUF
-
ECP
5h 00m
1 stop
$364Southwest
Thu, Aug 27 - Tue, Sep 1
Southwest Logo
10:00 am - 6:25 pm
ECP
-
BUF
7h 25m
2 stops
Southwest Logo
12:35 pm - 6:10 pm
BUF
-
ECP
6h 35m
2 stops
$365Southwest
Tue, Aug 25 - Sun, Aug 30
Southwest Logo
11:30 am - 9:45 pm
ECP
-
BUF
9h 15m
2 stops
Southwest Logo
6:20 am - 12:35 pm
BUF
-
ECP
7h 15m
2 stops
$369Southwest
Tue, Jul 21 - Fri, Jul 24
American Airlines Logo
4:17 pm - 10:51 pm
ECP
-
BUF
5h 34m
1 stop
American Airlines Logo
7:35 pm - 11:37 pm
BUF
-
ECP
5h 02m
1 stop
$372American Airlines
Fri, Aug 28 - Mon, Aug 31
American Airlines Logo
6:40 am - 4:56 pm
ECP
-
BUF
9h 16m
2 stops
American Airlines Logo
4:49 pm - 10:40 pm
BUF
-
ECP
6h 51m
1 stop
$374American Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Buffalo flights

Get data-powered insights and trends into flights from Panama City to Buffalo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Panama City to Buffalo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Panama City to Buffalo were found on Delta ($311) and American Airlines ($337).

Good to know

Cheapest flight$156
Flight from Panama City to Buffalo

When to book flights from Panama City to Buffalo

Are your dates flexible? Find out the best times to travel from Panama City to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Buffalo

  • What is the cheapest flight from Panama City to Buffalo?

    In the last 5 days, the lowest price for a flight from Panama City to Buffalo was $156 for a one-way ticket and $311 for a round-trip.

  • Do I need a passport to fly between Panama City and Buffalo?

    No, a passport isn't needed to fly from Panama City to Buffalo. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Panama City to Buffalo?

    Panama City airport is called Panama City NW Florida Beaches and the only airport in Buffalo is Buffalo.

  • Which aircraft models fly most regularly from Panama City to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Buffalo?

    oneworld is the only airline alliance operating flights between Panama City and Buffalo.

  • How does KAYAK find such low prices on flights from Panama City to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Panama City with another airline. Booking your flights between Panama City and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11765 reviews
7.9Crew
6.8Entertainment
7.2Comfort
6.4Food
7.5Boarding
Airline reviews

Terrible boarding and first class experience. Nice staff but overall disorganized, dirty plane.

4.0 OkayMarissa, Jun 2026
BOS - BUF
Read more American Airlines reviews

Terrible boarding and first class experience. Nice staff but overall disorganized, dirty plane.

This short sector between Miami and JFK was undertaken purely for business purposes, with efficiency as the primary objective rather than a full inflight experience. Overall, the journey met its intended purpose; however, the ground experience at Miami stood out significantly. During check-in, I was unable to link my frequent flyer details from Qatar Airways (oneworld alliance) through either the self-service kiosk or web check-in. The situation was handled exceptionally well by the check-in agent, who demonstrated remarkable ownership. She coordinated across multiple counters, ensured my frequent flyer number was correctly reflected, reissued the boarding pass, and confirmed that mileage accrual would be recognized. Additionally, she ensured the boarding pass reflected priority status, enabling a seamless priority check-in experience without delays. This level of proactive service was both commendable and impactful. Boarding and the inflight experience, operated by American Airlines under a codeshare arrangement, were efficient but largely transactional. While operational delivery was smooth, there was no visible recognition of oneworld frequent flyer status onboard. In comparison to the consistently personalized engagement typically experienced with Qatar Airways, this absence was noticeable—though understandably a potential limitation of codeshare alignment rather than a direct service shortfall. In summary, while the flight itself fulfilled its operational intent, the exceptional professionalism and commitment demonstrated at the Miami check-in counter was the defining highlight of this journey. Greater consistency in elite recognition across partner airlines would further enhance the overall experience.

I almost missed my flight and they helped me out enormously

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

The smell from the bathroom kept wafting through the cabin. It made people sick.

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Ok. Got us there safely and a bit early. Need food available on this long flight. Almost 3 hours.

Flight was delayed multiple times and I chose to switch to another flight that had a layover. I finally arrived 7 hours later than I was supposed to.

We liked quick boarding and on time departure. Seats were very uncomfortable.

It was quick, plane was loaded and the service on board was ok

Everything you need to know for your flight from Panama City to Buffalo

Information on your arrival and departure airports