$158 Find Cheap Flights from Panama City to Chicago - Compare and Save

The absolute cheapest return flight from Panama City to Chicago costs $315 on the route between Panama City (ECP) and Chicago O'Hare Intl Airport (ORD). However, over the past month, flights between Panama City (ECP) and Chicago Midway Airport (MDW) were, on average, 6% cheaper than other Panama City-Chicago routes. The most popular route is between Panama City (ECP) and Chicago O'Hare Intl Airport (ORD).

The cheapest month for flights from Panama City to Chicago is January, where tickets cost $269 (return) on average. On the other hand, the most expensive months are July and August, where the average cost of round-trip tickets is $461 and $457 respectively.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $318 on average.

To get a below average price on the flight from Panama City to Chicago, you should book around 4 weeks before departure, which saves you about 47% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

In the past 5 days, the cheapest round-trip tickets from Panama City to Chicago were found on American Airlines ($315) and Southwest ($315).

Panama City and Chicago are connected by different airlines. The airlines that fly that route the most regularly are United Airlines (8 flights per week), American Airlines (7 flights per week), and Southwest (5 flights per week).

Atlanta (ATL) is the top choice – 77% of KAYAK users who clicked on 1-stop flights from Panama City to Chicago picked an itinerary connecting there.

Flights via Washington, D.C. (DCA) offer the most affordable fares, with an average round-trip price of $258.

Consider flying via Atlanta (ATL) for the shortest journey. The average one-way travel time for flights connecting there is 4h 19m.

If you prefer a quick connection, Washington, D.C. (DCA) often has the shortest layovers from Panama City to Chicago, with an average of 0h 49m.

There are 4 cabin class options for the route. These are First, Business, Economy and Prem Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

Each day, there are between 2 and 4 nonstop flights that take off from Panama City and land in Chicago, with an average flight time of 2h 35m. The most common departure time is 1:00 pm and most flights take off in the afternoon, while the most flights land at Chicago O'Hare Intl Airport. Each week, there are 20 flights. The most frequent day of departure is Monday, when 20% of all weekly flights depart. The fewest flights depart on a Tuesday.