ECP - CHI

$153 Find Cheap Flights from Panama City to Chicago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Chicago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Chicago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Chicago, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$305
Typical prices: $344-$454
American Airlines
Wed 7/15Tue 7/21
ECP - ORD • Non-stop
Cheapest one-way
$153
Typical prices: $231-$380
United Airlines
Wed 7/22
ECP - ORD • Non-stop
Top airlines
Cheapest • from $305 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with American Airlines, United Airlines and Southwest. Average duration is 2h 31m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top routes
Cheapest • 28% average savings
Most popular
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $258 (round-trip)
Shortest trip • 4h 19m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 46% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 21% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Chicago!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Chicago (ECP-CHI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Chicago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Chicago

Wed, Jul 15 - Tue, Jul 21
American Airlines Logo
3:17 pm - 6:19 pm
ECP
-
ORD
3h 02mnonstop
American Airlines Logo
12:09 pm - 2:42 pm
ORD
-
ECP
2h 33mnonstop
$305American Airlines
Wed, Jul 15 - Wed, Jul 22
American Airlines Logo
3:17 pm - 6:19 pm
ECP
-
ORD
3h 02mnonstop
American Airlines Logo
5:07 am - 10:27 am
ORD
-
ECP
5h 20m
1 stop
$315American Airlines
Wed, Jul 15 - Wed, Jul 22
Southwest Logo
5:25 pm - 11:15 pm
ECP
-
MDW
5h 50m
1 stop
Southwest Logo
5:10 pm - 9:15 pm
MDW
-
ECP
4h 05m
1 stop
$325Southwest
Wed, Jul 15 - Tue, Jul 21
Delta Logo
2:47 pm - 8:33 pm
ECP
-
ORD
5h 46m
1 stop
Delta Logo
6:35 am - 10:48 am
ORD
-
ECP
4h 13m
1 stop
$325Delta
Wed, Jul 15 - Wed, Jul 22
American Airlines Logo
3:17 pm - 6:19 pm
ECP
-
ORD
3h 02mnonstop
American Airlines Logo
12:09 pm - 2:42 pm
ORD
-
ECP
2h 33mnonstop
$326American Airlines
Wed, Jul 15 - Wed, Jul 22
Southwest Logo
7:40 am - 3:10 pm
ECP
-
MDW
7h 30m
2 stops
Southwest Logo
5:10 pm - 9:15 pm
MDW
-
ECP
4h 05m
1 stop
$330Southwest
Wed, Jul 15 - Tue, Jul 21
Southwest Logo
7:40 am - 4:20 pm
ECP
-
MDW
8h 40m
2 stops
Southwest Logo
8:20 am - 3:40 pm
MDW
-
ECP
7h 20m
2 stops
$335Southwest
Sat, Sep 12 - Mon, Sep 14
Delta Logo
9:23 am - 4:30 pm
ECP
-
ORD
7h 07m
1 stop
Delta Logo
9:51 am - 3:31 pm
ORD
-
ECP
5h 40m
1 stop
$340Delta
Sat, Sep 12 - Mon, Sep 14
Delta Logo
9:23 am - 3:25 pm
ECP
-
MDW
6h 02m
1 stop
Delta Logo
5:10 pm - 11:15 pm
MDW
-
ECP
6h 05m
1 stop
$340Delta
Thu, Sep 10 - Mon, Sep 14
Southwest Logo
1:30 pm - 8:10 pm
ECP
-
MDW
6h 40m
1 stop
Southwest Logo
1:40 pm - 3:45 pm
MDW
-
ECP
2h 05mnonstop
$345Southwest
Booking Insights

KAYAK's insights & trends for Panama City to Chicago flights

Get data-powered insights and trends into flights from Panama City to Chicago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City, Florida to Chicago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City, Florida to Chicago departing in July.

What is the cheapest Panama City to Chicago flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest return flight from Panama City to Chicago costs $196 on the route between Panama City (ECP) and Chicago Midway Airport (MDW). Over the past month, this route was, on average, 28% cheaper than other Panama City-Chicago routes. The most popular route is between Panama City (ECP) and Chicago O'Hare Intl Airport (ORD).

What is the cheapest month to fly from Panama City to Chicago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Chicago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Chicago is May, where tickets cost $172 (return) on average. On the other hand, the most expensive months are July and November, where the average cost of round-trip tickets is $282 and $248 respectively.

Can I save money by flying with a layover from Panama City to Chicago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $318 on average.

How far in advance should I book a flight from Panama City to Chicago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Chicago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Chicago, you should book around 3 weeks before departure, which saves you about 46% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Chicago

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Blane Bachelor

Blane Bachelor

Expert on Southwest

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Good to know

Low seasonNovember
Cheapest flight$153
Best time to beat the crowds but there is an average 60% increase in price.
Most popular time to fly and prices are also 21% lower on average.
Flight from Panama City to Chicago O'Hare Airport

When to book flights from Panama City to Chicago

Are your dates flexible? Find out the best times to travel from Panama City to Chicago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Chicago

  • What is the cheapest flight from Panama City to Chicago?

    In the last 5 days, the lowest price for a flight from Panama City to Chicago was $153 for a one-way ticket and $305 for a round-trip.

  • Do I need a passport to fly between Panama City and Chicago?

    No, a passport isn't needed to fly from Panama City to Chicago. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Panama City to Chicago?

    Panama City is served by only 1 airport and there are 2 airports in Chicago. You will leave Panama City from Panama City NW Florida Beaches and you will be arriving in Chicago at one of these airports: Chicago Midway or Chicago O'Hare Intl.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Chicago?

    American Airlines, and Delta offer inflight Wi-Fi service on the Panama City to Chicago flight route.

  • Which aircraft models fly most regularly from Panama City to Chicago?

    The Embraer 175 is the aircraft model that flies most regularly on the Panama City to Chicago flight route.

  • Which airline alliances offer flights from Panama City to Chicago?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Chicago, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Chicago?

    There are nonstop flights from Panama City to Chicago on a daily basis.

  • Which is the best airline for flights from Panama City to Chicago, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Panama City to Chicago are Southwest and Delta. With an average price for the route of $303 and an overall rating of 7.9, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $323 and an overall rating of 7.8.

  • How does KAYAK find such low prices on flights from Panama City to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to Panama City with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Chicago

  • Looking for a cheap flight? 25% of our users found flights on this route for $216 or less one-way and $344 or less round-trip.

Prefer to fly direct from Panama City to Chicago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City NW Florida Beaches to Chicago.
Find which airlines fly direct from Panama City NW Florida Beaches Airport to Chicago, which days they fly and book direct flights.

Direct departures

Panama City NW Florida Beaches to Chicago

Monday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Tuesday

American Airlines,United Airlines

American Airlines,United Airlines

Wednesday

American Airlines,United Airlines

American Airlines,United Airlines

Thursday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Friday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Saturday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Sunday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

See more direct flights

Direct returns

Chicago to Panama City NW Florida Beaches

Monday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Tuesday

American Airlines,United Airlines

American Airlines,United Airlines

Wednesday

American Airlines,United Airlines

American Airlines,United Airlines

Thursday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Friday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Saturday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

Sunday

American Airlines,Southwest,United Airlines

American Airlines,Southwest, +1 more

See more direct flights

Reviews of the top 4 airlines serving from Panama City to Chicago

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Chicago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Chicago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4241 reviews
8.6Crew
8.0Comfort
8.1Boarding
7.5Entertainment
7.0Food
Airline reviews

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

2.0 MediocreMatthew, Jun 2026
CVG - MDW
Read more Southwest reviews

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

Kayak could’ve posted the correct gate number. Almost missed my flight.

Slow boarding, limited food and drink portions. Bad delays and turbulence

The flight was smooth. The Southwest experience has degraded overall, but this one was okay.

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

Truly terrible. Will never willingly fly southwest again. Seats are worse than before they switched to assigned seating. One flight attendant was the opposite of helpful (rude, unhelpful, dismissive, and as my stranger seatmate said unprompted: a total prick). This caused me, 15 minutes into the flight, to book an alternate return flight home on a competing airline (first class 1.2k purchase instead of my existing planned flight) just so I would not have to ever be on that aircraft, with that terrible service person, with those horrific seats ever again.

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

For the first time in a long time, the Wi-Fi actually worked the entire flight! The flight crew was amazing as usual.

Great flight. I didn't get a drink because I was asleep whole on the flight.

Communication about the delayed flight was poor. We were told to move gates three times but that was bad information. We went from gate 128 to gate 126 and then to gate 123 and back to gate 126. Communication about the delay was bad. Ended up being 1 1/2 hour late getting home.

Five hour delays every hour, I wish it were all at once

Got rerouted from a straight flight from Orlando to Atlanta to Knoxville to a flight from Orlando to Detroit to Knoxville! Seriously!! Flight delay out of Detroit! Long day for what should have been a pretty easy travel day!

Left /arrived on time. Decent seat space. Like the wifi/plugs and entertainment. Windows and tray table were kinda gross. Attendants didn't start snack service til 40mins before landing. Two rows before us, captain came on to say there's turbulence and recalled staff to seats. So, no drink/snack. Later, attendants didn't stop to see if we had trash nor even look our way. Felt invisible! Almost all pilot announcements were not only unintelligible, but so quiet. We had no idea what she said.

Gate agent was unhelpful for handicapped boarding. Flight attendant seemed untrained.

Clean planes and not take my comfort class seat away.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Aside from a completely packed plane, I really have no complaints.

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

Very easy ! Use the kiosk and bag drop and right to security within 10 min

Over 5 hour delay with minimal updates or ability to standby for alternative flights. During boarding and 1 hr+ wait for takeoff, seats were drenched w water from air conditioning condensation and always leftover crumbs on carpet and seats

Boarded early, left early, arrived 40 mins early! A win win for me!

These airplanes should be illegal. The seats are two tight, it is a safety issue. Wheelchair support was ridiculously slow. We almost missed our flight.

This flight is a quick way to get to Chicago, but a bit expensive.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

boarded early to only find out that flight would sit at gate for 45 min to an hour. Landed in chicago and sat on runway for over an hour before got to gate. Total delay was extensive for a 45 min flight door to door.

The flight was significantly delayed. The inbound flight from EWR was delayed departing because of mechanical problems. My original departure from CLT was 5:28 pm but due to the delay of the inbound flight, after arrival, deplaning, cleaning, boarding, we did not push back from the gate until 9:00 pm. Once in the air, the flight was smooth and what was originally supposed to be an arrival in ORD at 7:30 pm local time turned out to be 9:35 pm.

We had a mechanical delay which made us 90 minutes late (9:30 PM) then land and put into the penalty box because a plane was in our gate? What the hell! We should get priority.Damn American.

The seats were extremely cramped, with very little legroom or personal space. There was no room left in the overhead bins for a backpack, and the space under the seat in front was so limited that I could barely fit my bag underneath. Overall, the seating arrangement felt very uncomfortable and overcrowded.

weather delay of almost 2 hours then we landed and our gate wasn't available so we waited another 30 min

Delayed flight more than I hour. When boarding we spent some additional time on the plane before takeoff ....

The flight was delayed significantly and we sat on runway after landing for awhile. Best thing was the flight attendant, Jenny, in first class, who was very professional and attentive. She was excellent - the rest of the flight was not.

The flight attendants were extremely sourly and borderline rude. I did not feel appreciated as an AA customer once.

The flight from LA to Chicago was smooth and service was very good overall.

The Mario was so helpful and provided amazing customer service however l have being waiting for a callback for almost a week now and have not heard anything further after l informed them l wanted to change my date of traveling because of my hospital appointment even send them proof and l was unable to use manag your booking on their website is a bit frustrating and l would appreciate an update on My request as soon as possible. And have called them times without numbers no response

Awful, tons of delays, I got into Chicago multiple hours late meaning I hit the very traffic I tried so desperately to avoid. Just empty apologies from American Airlines text alerts. Trash behavior from a trash airline.

They lost my baggage and I am still struggling to the information and update

Everything you need to know for your flight from Panama City to Chicago

Information on your arrival and departure airports