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1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Panama City to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Miami
Miami1 stop$395
Key West
Key West1 stop$477
Miami
Miami1 stop$395
Key West
Key West1 stop$477
Booking Insights

Price, demand and travel trends for Panama City to Florida Keys flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Are flights from Panama City to Florida Keys cheaper or more expensive than last year?

Fares from Panama City to Florida Keys are about 22% higher than they were in November last year, averaging $495 round-trip.

What's the cheapest month to fly from Panama City to Florida Keys?

September is typically the cheapest month to fly from Panama City to Florida Keys, with round-trip fares averaging $415. March and August are usually the most expensive, averaging $674 and $658, respectively.

How do fares from Panama City to Florida Keys vary by day of the week?

On average, Thursday is the cheapest day to fly from Panama City to Florida Keys and Monday is the most expensive. Looking at the past 12 months of KAYAK data, it's 46% more expensive to fly on a Monday compared to Thursday.

What's the best time of day to fly from Panama City to Florida Keys?

It's cheapest to fly to Florida Keys in the evening with average prices of $415. The morning is the most expensive time to fly, with average prices of $477.

Key details for Panama City to Florida Keys flights

Low season

June
Beat the crowds with an average 29% drop in travelers.
The most popular month to fly with an average 49% increase in travelers.

Your Panama City to Florida Keys flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • How much should I budget for a flight from Panama City to Florida Keys?

    Over the past 12 months, round-trip fares from Panama City to Florida Keys have typically cost between $382 and $601.

  • Which airlines fly nonstop from Panama City to Florida Keys?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Panama City to Florida Keys. However, Delta offers a one-stop option.

  • Which cabin classes are available from Panama City to Florida Keys?

    On flights from Panama City to Florida Keys you can only book Economy Class.

  • What are some popular landmarks around Florida Keys?

    Florida Keys is home to many popular sights. KAYAK travelers' favorites include:

    • Duval Street
    • Kaseya Center
    • Bayfront Park
    • Bayside Marketplace

Your guide to booking Panama City to Florida Keys flights

Get tips on when to book, when to fly and what to know before your trip.
  • Flexible with your dates? Fly in September to save some money. It's typically the cheapest month on this route, while flights in March will cost you the most.
  • Fly out on a Thursday to get the cheapest fares. Avoid Monday flights, which are about 46% more expensive.
  • Start your trip in Miami, the most popular destination in Florida Keys. From there, it's easy to continue on to other popular spots such as Key West, Islamorada and Key Largo.

Reviews of the top airlines flying from Panama City to Florida Keys

 
Need help choosing which airline to fly with from Panama City to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8719 reviews
8.1Boarding
7.8Comfort
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

I had a great flight with delta. Plane was clean and the staff was nice, I would fly again with delta.

10.0 ExcellentBr, Nov 2026
Read more Delta reviews

I had a great flight with delta. Plane was clean and the staff was nice, I would fly again with delta.

Flight attendent didn't let me sit in the empty window seat literally next to me. Doors had closed already so I moved over. She came over, asked for my ticket and made me switch back to the middle. The man on the aisle and I were right on top of each other. Seemed like a real power trip for no reason at all.

Good but since we got in early we had to wait on runway for our gate. That was kind of a bummer but we still got in earlier than planned For entertainment I was watching a movie and getting close to the end of it with 15 min left but it kept jumping automatically to the next movie before finishing.

Delta seems to be getting worse. They are trying to take any comfort away from poorer people to make more money selling it to the rich. I paid for delta comfort and on my flight from Rome to jfk I had a tv that would go on and off automatically and literally no electrical outlets or usbs worked which was advertised in the price of the fare. The infotainment system wasn’t fully working. Luckily the movies worked and the plane was needing a lot of repairs. The jfk to Tampa flight they stuck me next to this really larger guy who was half in my seat and they should have made other accommodations for him because now you’re interfering with the fare class I paid for and act like I shouldn’t care because I didn’t pay for first class. I couldn’t even pull out my tray table because of this guy. The safety video tv screen you couldn’t even see it. It made me a little scared to fly delta anymore, because if these planes are this much in need of servicing, I have to wonder if the plane is going to make it to the destination.

Late flight, screens not working and still had to pay for a drink

They changed my seat assignment from window to middle. I have a physical need to sit by the window because of spinal issues. I unboarded in pain, I also was placed between 2 very large men. I am very disappointed and now dealing with the physical aftermath.

The crew were awesome and ready to help as much as possible. The gate agent in Atlanta was tremendously helpful. The delays were ridiculous. Getting home at 4am when I could have driven home faster was unimpressive. Being delayed for countless hours through the night wasn't a great travel experience.

We sat at the gate for over 30 minutes, with no indication as to why

Flight Staff: Always great! Checking back vs carry-on: I typically check my bag since so much time is spent stowing the bag, it's heavy, maybe not enough room. Delta is charging $45 to check bags. Yet, the people who have multiple carry-on bags are then asked to check their bags and are offered this service for free. This does not seem fair to a person who is trying to be proactive in improving the process . Boarding: Boarding is always slow and exhausting. With the exception of First Class, Economy, why not board the zone in the back of the plane first??? Seats: Why cross the seat belts? I get that it looks nice, but people waste so much time moving them or sitting on them and then having to move. Seats: On both my flights the seat did not recline. Not a big deal. Smell: There was a horrific smell like the restrooms on my first flight. I thought I was going to be sick. Most flights do not smell great. Does Delta use air purifiers or anything?

Planes were clean, no water or snacks on either flight.

Good flight, excellent personnel; poor comfort, small seats, big cost.

Both the gate agent and flight crew did a horrible job of expediting the boarding process. It was simply miss managed. The airplane was late to Tampa. Therefore, they should have expedited the de-boarding process and also boarding process. This did not happen and caused me to miss my connection. I ended up with a 7 hour hour layover just to get home. The overall flying experience on American has simply been degraded. On-time performance is a real problem every single week. This has caused me to consider moving my loyalty to an airline that has better performance metrics.

It was ok because it’s a short flight. The attendants weren’t friendly and didn’t serve any beverages even through they announced that they would. Also. The attendants looked messy, not presentable

Quick flight. No time to stress over it. Over before it begins.

It was awful. My first flight was delayed and as a consequence I lost my second flight to Greensboro. I did not know what to do so I rebook myself a flight to Charlotte . It was very inconvenient I not to have anybody form corporate assisting me either from PwC or from kayak . It is a very disappointing experience that American did not wait 1 minute or told me to rebook before making the first flight

It was awful. The communication between corporate and the crew on the ground left more to be desired. The crew even said that Corporate was waiting on answers because they themselves didn't know. Every hour, there was a new excuse. I also understood that passengers were angry, but the crew should have done a better job at crowd control. There was a racial exchange between passengers that could've been avoided has the crew acted sooner.

We sat on plane at gate delayed without communication as to why we were just sitting there

Little time between flight from Dallas to flight to Gainesville. We chose this one, 43 minutes between, because the price for a connection with at least an hour between, was so much higher. Had to ask passengers on the Dallas flight to please allow us to deplane ahead of them. The economy passengers allowed this. We had to walk very fast to the next gate, 35 gates away. Thankfully all in the same terminal. Getting to the small Gainesville plane was a little confusing as you enter an area that is boarding many small planes at the same time. We stood in the wrong line for about 15 seconds before realizing it was not our Gainesville flight. Since I had boarded at this gate in the past, I knew to check the signs carefully so we weren’t lost. The first class seat experience was wonderful. I really enjoyed the upgrade. We were offered an alcohol drink as soon as we sat down. I got something different but it was a great gesture especially since we really had to hurry to make the flight. We had packed expecting we might miss this connection, but made it. Our luggage didn’t miss the flight. American Airlines delivered our bags to our home the next day. That was very convenient!

Incredibly delayed. First delay was due to plane coming in being late. Resulted in 30 minute delay. Boarded and then had multiple mechanical issues. Was on plane for an hour until they told people they could get off if they wanted but couldn't come back. Then gate agent rushed in and said they had lost control of who went off and we would all have to deplane and then get back on. They said flight had not been cancelled. Then while sitting waiting to board again they announced it would take two hours to get new plane and to wait at new gate. New plane arrived, reboarded only to find out that pilots had timed out. Waited for new pilots. In that time one of the flight attendants timed out. Never received food or water while waiting. Was confusing mess as to what was happening. Even flight attendants and gate agents were getting frustrated. Almost 6 hours delayed. Called American to received flight credit but can't get anywhere as Kayak reservation and don't have a ticket number. Reached out to Kayak but never heard back.

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

More options for your flight to Florida Keys

Complete your trip to Florida Keys with a hotel stay or car rental