$159 Find Cheap Flights from Panama City to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Florida Keys departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$317
Key West
Key West1 stop$307
Miami
Miami1 stop$317
Key West
Key West1 stop$307

Book Cheap Panama City to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Florida Keys

Wed, Mar 18 - Wed, Mar 25
Delta Logo
1:30 pm - 7:44 pmECP-EYW
5h 14m1 stop
Delta Logo
2:35 pm - 6:58 pmEYW-ECP
5h 23m1 stop
$307Delta
Find Deal
Thu, Dec 11 - Tue, Dec 16
Delta Logo
1:32 pm - 8:06 pmECP-EYW
5h 34m1 stop
Delta Logo
6:10 pm - 10:37 pmEYW-ECP
5h 27m1 stop
$317Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11
Delta Logo
7:45 am - 3:47 pmECP-MIA
7h 02m1 stop
Delta Logo
7:00 am - 12:40 pmMIA-ECP
6h 40m1 stop
$317Delta
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Thu, Dec 11 - Wed, Dec 17
Delta Logo
6:59 pm - 12:46 amECP-MIA
4h 47m1 stop
Delta Logo
7:00 am - 12:47 pmMIA-ECP
6h 47m1 stop
$318Delta
Find Deal
Thu, Dec 11 - Tue, Dec 16
American Airlines Logo
7:15 am - 7:35 pmECP-EYW
11h 20m2 stops
American Airlines Logo
6:33 pm - 11:10 pmEYW-ECP
5h 37m1 stop
$322American Airlines
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Thu, Dec 11 - Tue, Dec 16
American Airlines Logo
7:15 am - 7:35 pmECP-EYW
11h 20m2 stops
American Airlines Logo
7:00 am - 4:47 pmEYW-ECP
10h 47m2 stops
$327American Airlines
Find Deal
Fri, Dec 12 - Mon, Dec 15
American Airlines Logo
12:08 pm - 5:52 pmECP-EYW
4h 44m1 stop
American Airlines Logo
4:10 pm - 11:10 pmEYW-ECP
8h 00m2 stops
$332American Airlines
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Fri, Jan 9 - Sat, Jan 17
Delta Logo
7:18 am - 12:14 pmECP-MIA
3h 56m1 stop
Delta Logo
6:00 am - 9:07 amMIA-ECP
4h 07m1 stop
$337Delta
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Thu, Dec 11 - Wed, Dec 17
American Airlines Logo
2:43 pm - 10:33 pmECP-MIA
6h 50m1 stop
American Airlines Logo
5:33 pm - 11:10 pmMIA-ECP
6h 37m1 stop
$339American Airlines
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Wed, Mar 18 - Tue, Mar 24
Delta Logo
1:30 pm - 7:44 pmECP-EYW
5h 14m1 stop
Delta Logo
7:00 am - 10:17 amEYW-ECP
4h 17m1 stop
$353Delta
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to Florida Keys flights

Get data-powered insights and trends into flights from Panama City to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Panama City to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $379, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Panama City to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Florida Keys is August, when tickets cost $298 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $597 and $517 respectively.

How far in advance should I book a flight from Panama City to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Florida Keys, you should book around 3 weeks before departure, which saves you about 37% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$159
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 23% lower on average.
Flight from Panama City to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Panama City to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Panama City to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4235 reviews
8.0Comfort
8.6Crew
7.5Entertainment
7.0Food
8.1Boarding
Airline reviews

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

6.0 GoodDavid, Aug 2025MCO - DEN
Read more Southwest reviews

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

Everything was on time. I was disappointed by the front section female, African American flight attendant. I did not see her name tag or would have identified by name not race. As passengers moved to the bathroom early in flight, she would say with a disdainful tone “I have to say the seat belt light is on” then go back to her book. Better trained flight attendants say something like be careful the seat belt light is on.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

It is southwest seat was ok. Not the most comfortable seat

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

Plz don't take away free bags and free seating

WiFi on the flight was not working. Thus, entertainment options were limited.

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

The flight was an hour and a half late departing which was inconvenient

The flight was great. The gate location was way to far away!!!

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

We didn't take off until an hour after we boarded.

Wish they had the seat-back video screens for watching movies or playing games.

Very good but wish they had the seat-back video screens for movies & games

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

This flight never occurred because AA couldn’t get their act together.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

Everything you need to know for your flight to Florida Keys

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