$79 Find Cheap Flights from Panama City to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Florida Keys departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 20% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flights Deals
Useful Info
Flights Deals

Best Florida Keys Flight Deals from Panama City

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$159
Key West
Key West1 stop$329
Miami
Miami1 stop$159
Key West
Key West1 stop$329

Cheap Flights from Panama City to Florida Keys

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Florida Keys

Wed, Sep 3 - Mon, Sep 8
American Airlines Logo
6:07 pm - 11:56 pmECP-MIA
4h 49m1 stop
American Airlines Logo
5:00 am - 11:31 amMIA-ECP
7h 31m1 stop
$159American Airlines
Find Deal
Mon, Aug 11 - Mon, Aug 18
Southwest Logo
10:40 am - 8:45 pmECP-MIA
9h 05m1 stop
Southwest Logo
8:00 am - 4:40 pmMIA-ECP
9h 40m1 stop
$168Southwest
Find Deal
Mon, Aug 11 - Mon, Aug 18
Southwest Logo
7:25 am - 4:20 pmECP-MIA
7h 55m2 stops
Southwest Logo
7:10 am - 9:00 pmMIA-ECP
14h 50m2 stops
$173Southwest
Find Deal
Wed, Jul 30 - Tue, Aug 5
Delta Logo
1:12 pm - 9:18 pmECP-MIA
7h 06m1 stop
Delta Logo
5:30 am - 8:33 amMIA-ECP
4h 03m1 stop
$203Delta
Find Deal
Thu, Aug 14 - Mon, Aug 18
American Airlines Logo
2:33 pm - 11:17 pmECP-MIA
7h 44m1 stop
American Airlines Logo
5:18 am - 11:36 amMIA-ECP
7h 18m1 stop
$213American Airlines
Find Deal
Sat, Sep 27 - Mon, Sep 29
Southwest Logo
9:45 am - 8:35 pmECP-MIA
9h 50m2 stops
Southwest Logo
4:40 pm - 9:00 pmMIA-ECP
5h 20m1 stop
$217Southwest
Find Deal
Fri, Sep 26 - Mon, Sep 29
American Airlines Logo
6:06 pm - 11:56 pmECP-MIA
4h 50m1 stop
American Airlines Logo
5:00 am - 11:31 amMIA-ECP
7h 31m1 stop
$233American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
Delta Logo
11:15 am - 6:48 pmECP-MIA
6h 33m1 stop
Delta Logo
6:00 am - 10:15 amMIA-ECP
5h 15m1 stop
$267Delta
Find Deal
Thu, Aug 14 - Mon, Aug 18
United Airlines Logo
6:30 am - 8:45 pmECP-MIA
13h 15m1 stop
United Airlines Logo
4:53 pm - 1:05 pmMIA-ECP
21h 12m2 stops
$518United Airlines
Find Deal
Mon, Jul 14 - Mon, Jul 21
United Airlines Logo
5:02 pm - 10:39 pmECP-MIA
28h 37m1 stop
United Airlines Logo
6:35 pm - 4:21 pmMIA-ECP
22h 46m2 stops
$622United Airlines
Find Deal
Useful Info

KAYAK's insights & trends for Panama City to Florida Keys flights

Get data-powered insights and trends into flights from Panama City to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Panama City to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $483, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Panama City to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Florida Keys is January, when tickets cost $341 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $597 and $573 respectively.

How far in advance should I book a flight from Panama City to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Florida Keys, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.


Good to know

Low seasonApril
High seasonDecember
Cheapest flight$79
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 8% increase in price.
Flight from Panama City to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Panama City to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Panama City to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4280 reviews
8.6Crew
8.0Comfort
7.6Entertainment
7.1Food
8.2Boarding
Airline reviews

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

6.0 GoodVincent, May 2025MDW - MCO
Read more Southwest reviews

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

It is southwest seat was ok. Not the most comfortable seat

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

Plz don't take away free bags and free seating

WiFi on the flight was not working. Thus, entertainment options were limited.

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

Excellent! Only question is how we check in at exactly 24 hours in advance and end up at the end of the B boarding group

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

It went well. Plane wasn't full. Will be great when assigned seating is in place

Planes are aged. The wifi is unreliable and on many fights, no-existent. The flight attendants were very good.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

I am very bothered by the events today. I can't believe the flight attendants allowed someone to take my seat and made me move. It was embarrassing. I was in the right. The lady just didn't want move. I can't believe delta would allow this to stand and disrespect my rights as a passenger. The lady complained about her leg and that she couldn't move. Firstly somehow she was able to make it to row 24. Not sure how much her leg could have hurt. Secondly, I'm in plenty of pain myself. I just finished chemotherapy a several weeks ago. My body is constantly sore. Yet deltas flight attendants didn't appropriately protect my rights. In the end they found me a seat on the plane but I want to understand how delta can operate this way. They in essence allowed a bully to get their way.

Crew was friendly Love the entertainment in the seat head rest.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

Newer plane, relatively easy boarding, not a full flight and was told that we could not be moved up because of weight and balance issues. Otherwise, a very good experience.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

Would have thought that they would gas up plane before everyone got on board

Fine. On time, cabin service was fine, bag arrived. All good. Flying into DCA so did not collide with any helicopters, which is also good. Horrid incident that could have and should have been prevented.

Standard. No different than a discount carrier on a short trip.

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Checking in at the counter was very disappointing. The lady had a very bad attitude and smart at me. She had no smile, did not greet me by name, or acknowledge me as a valued customer. Poor reflection of the airline.

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.