ECP

$179 Find Cheap Flights from Florida Keys to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$317
Delta
Fri 1/23Tue 1/27
EYW - ECP • 1 stop
Cheapest one-way
$179
Typical prices: $287-$328
Delta
Sun 1/25
MIA - ECP • 1 stop
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Flight Deals
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Flight Deals

Cheap Flights from Florida Keys to Panama City

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to Panama City

Fri, Jan 23 - Tue, Jan 27
Delta Logo
2:45 pm - 7:50 pmEYW-ECP
6h 05m1 stop
Delta Logo
12:15 pm - 7:40 pmECP-EYW
6h 25m1 stop
$317Delta
Find Deal
Tue, Feb 17 - Thu, Feb 19
Delta Logo
1:28 pm - 4:26 pmMIA-ECP
3h 58m1 stop
Delta Logo
6:06 pm - 12:53 amECP-MIA
5h 47m1 stop
$317Delta
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Wed, Jan 21 - Sat, Jan 24
Delta Logo
5:50 am - 11:08 amMIA-ECP
6h 18m1 stop
Delta Logo
4:45 pm - 12:51 amECP-MIA
7h 06m1 stop
$337Delta
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Wed, Jan 21 - Sat, Jan 24
Delta Logo
1:21 pm - 6:14 pmMIA-ECP
5h 53m1 stop
Delta Logo
4:45 pm - 10:26 amECP-MIA
16h 41m2 stops
$355Delta
Find Deal
Fri, Jan 16 - Mon, Jan 19
Delta Logo
5:50 am - 9:12 amMIA-ECP
4h 22m1 stop
Delta Logo
7:20 am - 3:27 pmECP-MIA
7h 07m1 stop
$357Delta
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Tue, Dec 9 - Sat, Dec 13
Delta Logo
7:40 am - 12:47 pmEYW-ECP
6h 07m1 stop
Delta Logo
10:00 am - 5:15 pmECP-EYW
6h 15m1 stop
$359Delta
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Tue, Dec 9 - Sat, Dec 13
American Airlines Logo
1:33 pm - 11:10 pmEYW-ECP
10h 37m2 stops
American Airlines Logo
7:15 am - 4:12 pmECP-EYW
7h 57m1 stop
$364American Airlines
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Tue, Dec 23 - Tue, Dec 30
American Airlines Logo
6:00 am - 9:56 amMIA-ECP
4h 56m1 stop
American Airlines Logo
4:09 pm - 10:48 pmECP-MIA
5h 39m1 stop
$422American Airlines
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Tue, Dec 23 - Tue, Dec 30
Southwest Logo
6:30 am - 3:35 pmMIA-ECP
10h 05m2 stops
Southwest Logo
6:35 pm - 12:05 amECP-MIA
4h 30m1 stop
$436Southwest
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Fri, Dec 19 - Sun, Dec 21
American Airlines Logo
6:00 am - 9:56 amMIA-ECP
4h 56m1 stop
American Airlines Logo
4:09 pm - 12:47 amECP-MIA
7h 38m1 stop
$437American Airlines
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Good to know

Low seasonJanuary
Cheapest flight$179
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Miami to Panama City

FAQs for booking flights from Florida Keys to Panama City

  • How does KAYAK find such low prices on flights from Florida Keys to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Florida Keys to Panama City

 
Need help choosing which airline to fly with from Florida Keys to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7998 reviews
7.9Comfort
7.3Food
7.9Entertainment
8.5Crew
8.1Boarding
Airline reviews

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

2.0 MediocreAnonymous, Nov 2025ATL - TPA
Read more Delta reviews

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

The flight was an hour and a half late departing which was inconvenient

The flight was great. The gate location was way to far away!!!

Delays to take off and to leave the plane after landing added a lot of time to this flight.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

We didn't take off until an hour after we boarded.

Wish they had the seat-back video screens for watching movies or playing games.

Very good but wish they had the seat-back video screens for movies & games

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

This flight never occurred because AA couldn’t get their act together.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

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