$259 Find Cheap Flights from Panama City to South Dakota

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to South Dakota departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Dakota

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to South Dakota, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to South Dakota, as well as popular online travel agencies
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Flight Deals

Book Cheap Panama City to South Dakota Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to South Dakota that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to South Dakota

Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
3:22 pm - 9:09 pmECP-FSD
5h 47m1 stop
American Airlines Logo
6:30 am - 12:28 pmFSD-ECP
5h 58m1 stop
$259American Airlines
Find Deal
Tue, Nov 11 - Tue, Nov 18
Delta Logo
5:00 pm - 11:09 pmECP-FSD
6h 09m1 stop
Delta Logo
4:19 pm - 10:37 pmFSD-ECP
6h 18m2 stops
$264Delta
Find Deal
Tue, Nov 11 - Tue, Nov 18
Delta Logo
6:00 am - 3:39 pmECP-FSD
9h 39m2 stops
Delta Logo
1:30 pm - 10:37 pmFSD-ECP
9h 07m2 stops
$309Delta
Find Deal
Tue, Nov 11 - Tue, Nov 18
Delta Logo
6:00 am - 3:39 pmECP-FSD
9h 39m2 stops
Delta Logo
1:30 pm - 10:37 pmFSD-ECP
9h 07m2 stops
$334Delta
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
11:04 am - 9:09 pmECP-FSD
10h 05m2 stops
American Airlines Logo
6:30 am - 12:28 pmFSD-ECP
5h 58m1 stop
$376American Airlines
Find Deal
Mon, Nov 10 - Sun, Nov 16
American Airlines Logo
5:55 pm - 10:28 amECP-FSD
16h 33m2 stops
American Airlines Logo
6:30 am - 2:52 pmFSD-ECP
8h 22m1 stop
$477American Airlines
Find Deal
Mon, Nov 10 - Sun, Nov 16
American Airlines Logo
1:11 pm - 9:10 pmECP-FSD
7h 59m1 stop
American Airlines Logo
6:30 am - 2:52 pmFSD-ECP
8h 22m1 stop
$550American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
11:04 am - 6:45 pmECP-FSD
7h 41m2 stops
American Airlines Logo
7:16 pm - 11:29 amFSD-ECP
16h 13m2 stops
$564American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
11:04 am - 9:09 pmECP-FSD
10h 05m2 stops
American Airlines Logo
1:43 pm - 11:49 pmFSD-ECP
10h 06m2 stops
$639American Airlines
Find Deal
Mon, Nov 10 - Sun, Nov 16
United Airlines Logo
10:04 am - 11:44 pmECP-FSD
13h 40m3 stops
United Airlines Logo
8:00 am - 4:23 pmFSD-ECP
8h 23m2 stops
$1,268United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to South Dakota flights

Get data-powered insights and trends into flights from Panama City to South Dakota to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Panama City and South Dakota?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Panama City to South Dakota.

There are 2 airlines that fly nonstop from Panama City to South Dakota. They are American Airlines and Delta. The cheapest airline for this route is Delta, with the best round-trip deal found costing $258 and arriving in Sioux Falls (FSD). On average, Delta offers the best prices for nonstop flights between Panama City and South Dakota.

Which airlines provide the cheapest flights from Panama City to South Dakota?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Panama City to South Dakota were found on American Airlines ($259) and Delta ($264).

Good to know

Low seasonAugust
Cheapest flight$259
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly and prices are also 30% lower on average.
Flight from Panama City to Sioux Falls

FAQs - booking South Dakota flights

  • How does KAYAK find such low prices on flights from Panama City to South Dakota?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to South Dakota.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to South Dakota?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to South Dakota is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to South Dakota?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to South Dakota with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to South Dakota?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to South Dakota up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to South Dakota

 
See real verified KAYAK customer reviews for airlines flying from Panama City to South Dakota. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to South Dakota? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7975 reviews
7.3Food
8.5Crew
7.9Comfort
7.9Entertainment
8.2Boarding
Airline reviews

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

8.0 ExcellentOlaf, Sep 2025FLL - ATL
Read more Delta reviews

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

We had 3 flights. 1 & 2 were on the same plane but we had to de-board just to re-board 30 mins later. That may have been due to a crew change though. Our 3rd flight had a couple “maintenance” issues that held us up. They were quickly resolved but it took forever for someone to bring the paperwork needed so we could leave. Apparently there was a computer glitch so a driver had to bring a physical copy. It delayed us about 1 1/2 hrs. The flights themselves were smooth & no problems. For boarding, I don’t know why they don’t start with the back of the plane & move forward. It would eliminate the back up from people trying to find their seats & put their bags in the overhead bins. Unless you’re on an overseas flight, there is no food, you get a beverage & either a small bag of pretzels or a biscuit cookie. Take your own food or snacks of you want something more.

Lost bag and 2 days no word leaving for cruise no clothes or stuff

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Food was ok, but not as good as I have had before on AA.

Pretty good. The food was just mediocre, the boarding and crew were good.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

The delays and cancellations kept me stuck in Miami for an additional 24 hours, and the whole thing seemed extremely disorganized

Everything you need to know for your flight from Panama City to South Dakota

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