PTY - IND

$331 Find Cheap Flights from Panama City to Indianapolis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Indianapolis departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Indianapolis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Indianapolis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Indianapolis, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$484
Typical prices: $715-$612
American Airlines
Tue 10/6Thu 10/15
PTY - IND • 1 stop
Cheapest one-way
$320
Multiple Airlines
Sun 5/17
PTY - IND • 3 stops
Top airlines
Cheapest • from $484 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Panama City and Indianapolis. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $683 (round-trip)
Shortest trip • 8h 09m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 17% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Indianapolis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Indianapolis (PTY-IND)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Indianapolis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Indianapolis

Tue, Oct 6 - Thu, Oct 15
American Airlines Logo
3:35 pm - 6:17 pm
PTY
-
IND
25h 42m
1 stop
American Airlines Logo
7:05 pm - 2:00 pm
IND
-
PTY
19h 55m
1 stop
$484American Airlines
Tue, Oct 6 - Thu, Oct 15
American Airlines Logo
3:35 pm - 1:47 pm
PTY
-
IND
21h 12m
2 stops
American Airlines Logo
7:05 pm - 2:00 pm
IND
-
PTY
19h 55m
1 stop
$489American Airlines
Wed, May 13 - Sat, May 30
Delta Logo
2:15 pm - 11:26 pm
PTY
-
IND
8h 11m
1 stop
Delta Logo
6:00 am - 12:50 pm
IND
-
PTY
7h 50m
1 stop
$585Delta
Tue, Jun 2 - Thu, Jul 23
American Airlines Logo
1:14 pm - 11:41 am
PTY
-
IND
21h 27m
2 stops
American Airlines Logo
6:40 pm - 12:14 pm
IND
-
PTY
18h 34m
1 stop
$600American Airlines
Fri, May 8 - Tue, May 12
Delta Logo
2:15 pm - 12:33 am
PTY
-
IND
9h 18m
1 stop
Delta Logo
5:01 pm - 12:50 pm
IND
-
PTY
20h 49m
1 stop
$601Delta
Mon, May 18 - Fri, May 29
Multiple Airlines Logo
9:33 pm - 11:03 am
PTY
-
IND
36h 30m
2 stops
Multiple Airlines Logo
12:14 pm - 8:34 pm
IND
-
PTY
9h 20m
1 stop
$612Multiple Airlines
Thu, May 28 - Thu, Jun 4
American Airlines Logo
1:14 pm - 11:49 am
PTY
-
IND
21h 35m
2 stops
American Airlines Logo
7:28 pm - 12:13 pm
IND
-
PTY
17h 45m
1 stop
$633American Airlines
Wed, May 13 - Sat, May 30
American Airlines Logo
1:49 pm - 9:41 am
PTY
-
IND
18h 52m
2 stops
American Airlines Logo
5:45 am - 12:14 pm
IND
-
PTY
7h 29m
1 stop
$638American Airlines
Fri, May 8 - Sat, May 16
Delta Logo
2:15 pm - 12:33 am
PTY
-
IND
9h 18m
1 stop
Delta Logo
6:00 am - 12:50 pm
IND
-
PTY
7h 50m
1 stop
$641Delta
Wed, Jul 22 - Mon, Jul 27
American Airlines Logo
1:14 pm - 12:43 pm
PTY
-
IND
22h 29m
2 stops
American Airlines Logo
5:17 pm - 12:14 pm
IND
-
PTY
19h 57m
2 stops
$644American Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Indianapolis flights

Get data-powered insights and trends into flights from Panama City to Indianapolis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Indianapolis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Indianapolis departing in October.

What is the cheapest month to fly from Panama City to Indianapolis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Indianapolis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Indianapolis is November, where tickets cost $526 (return) on average. On the other hand, the most expensive months are March and September, where the average cost of round-trip tickets is $788 and $748 respectively.

Good to know

Low seasonNovember
Cheapest flight$320
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Panama City to Indianapolis

When to book flights from Panama City to Indianapolis

Are your dates flexible? Find out the best times to travel from Panama City to Indianapolis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Indianapolis

  • What is the cheapest flight from Panama City to Indianapolis?

    In the last 3 days, the lowest price for a flight from Panama City to Indianapolis was $320 for a one-way ticket and $484 for a round-trip.

  • Do I need a passport to fly between Panama City and Indianapolis?

    A passport is required to fly from Panama City to Indianapolis.

  • Which aircraft models fly most regularly from Panama City to Indianapolis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Indianapolis?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Indianapolis, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Indianapolis, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Indianapolis are Delta and Copa Airlines. With an average price for the route of $612 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $643 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Panama City to Indianapolis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Indianapolis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Indianapolis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Indianapolis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Indianapolis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Indianapolis with an airline and back to Panama City with another airline. Booking your flights between Panama City and IND can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Indianapolis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Indianapolis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Panama City to Indianapolis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Indianapolis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Indianapolis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8466 reviews
7.9Comfort
8.5Crew
7.2Food
8.1Boarding
7.8Entertainment
Airline reviews

Round trip flight to Canada and back to the US was smooth and efficient.

8.0 ExcellentBrent, Apr 2026
YWG - MSP
Read more Delta reviews

Round trip flight to Canada and back to the US was smooth and efficient.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

Spanish speaker flight attendants were incredibly rude. A male flight attendant named Allen, grabbed my bag out of the overhead bin and moved it without my permission. When I asked what he was doing, he informed me that the overhead bins were public space? It would be easy to ignore this comment, as you don’t know the whole story, but the flight attendants were militant and rude. Delta, you can do better!

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

My business class seat was inoperable and unable to recline for 10 hour flight.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Flight crew was super friendly and helpful. Food was frequent and honestly pretty good. Plenty of on-board entertainment. Economy seats are super cramped for such a long flight, but the crew allowed people to get up and stretch, and kids could wander with their parents, so we all made it work. Overall a very good experience.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

Outstanding service, great food, friendly & efficient crew, safe & comfortable flight

Staff were not attentive, wifi did not work, cut my head in the bathroom due to the position of the soap on the sink, had blood running down my face, told staff, they had no expression no sympathy, didn't even say "sorry", they said "oh we will have a look at that" about 10 mins later the purser brought me a bandaid, still no sorry.... Shocking

Starlink is great Crew was polite Business class didn’t get a welcome drink just water and snacks were ok

Everything you need to know for your flight from Panama City to Indianapolis

Information on your arrival and departure airports