Which airports can I use when flying from San Diego to Santa Cruz de la Sierra?

Flights from San Diego to Santa Cruz de la Sierra usually depart from San Diego (SAN) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

What cabin classes can I book on flights from San Diego to Santa Cruz de la Sierra?

Two cabin classes are available on flights from San Diego to Santa Cruz de la Sierra: • Economy Class • First Class

Which airports do connecting flights from San Diego to Santa Cruz de la Sierra pass through?

Most connecting flights from San Diego to Santa Cruz de la Sierra pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.

Can I save money by using flexible dates for flights from San Diego to Santa Cruz de la Sierra?

Yes. Flexible dates can save you up to 65% on flights from San Diego to Santa Cruz de la Sierra. Tuesday is the cheapest departure day at $689 round-trip on average, while Thursday is the most expensive at $1,918, a difference of $1,229. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Do I need a passport to fly from San Diego to Santa Cruz de la Sierra?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from San Diego to Santa Cruz de la Sierra changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $728 to $2,069. That means the highest observed fare was about 3x higher than the lowest one.

How are flight prices from San Diego to Santa Cruz de la Sierra looking right now?

One-way fares from San Diego to Santa Cruz de la Sierra are currently higher than usual. Average one-way flight prices are about $675, which is 41% above the typical average for this route.

What is the time difference between San Diego and Santa Cruz de la Sierra?

Santa Cruz de la Sierra is 3 hours ahead of San Diego (Bolivia Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

How much is a round-trip flight from San Diego to Santa Cruz de la Sierra?

Round-trip flights from San Diego to Santa Cruz de la Sierra typically range from $858 to $1,709. The lowest price found in the past 5 days was $728, on Copa Airlines.

Which airline is the cheapest to fly from San Diego to Santa Cruz de la Sierra?

Copa Airlines ($728) and United Airlines ($1,089) are the cheapest airlines to fly round-trip from San Diego to Santa Cruz de la Sierra according to KAYAK data over the last 5 days.

What is the cheapest layover airport when flying from San Diego to Santa Cruz de la Sierra?

Flights via Panama City Tocumen Intl (PTY) offer the most affordable fares, with an average round-trip price of $770. Based on KAYAK data over the past 3 months.

When flying from San Diego to Santa Cruz de la Sierra which airport offers the shortest layover?

Panama City Tocumen Intl (PTY) had the shortest average connection time for San Diego to Santa Cruz de la Sierra layovers at 14h 54m over the past 3 months.

$434 CHEAP FLIGHTS from San Diego to Santa Cruz de la Sierra (SAN - VVI)

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Cheapest round-trip

$728

Typical prices: $858-$1,709

Copa Airlines

Tue 4/3Sun 4/8

SAN - VVI • 1 stop

Cheapest one-way

$434

Typical prices: $359-$837

United Airlines

Thu 10/18

SAN - VVI • 2 stops

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We hope you love your trip to Santa Cruz de la Sierra!

Flight Deals

Cheap Flights from San Diego to Santa Cruz de la Sierra (SAN-VVI)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from San Diego to Santa Cruz de la Sierra

Sat, Apr 3 - Thu, Apr 8

8:04 pm - 3:55 amSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

28h 51m1 stop Panama City Tocumen Intl

12:55 am - 6:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

20h 35m1 stop Panama City Tocumen Intl

$728Copa Airlines

Thu, Nov 5 - Wed, Nov 11

4:45 pm - 10:38 pmSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

25h 53m2 stops Los Angeles Panama City Tocumen Intl

3:45 am - 5:53 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

18h 08m2 stops Bogotá El Dorado Houston George Bush Intcntl

$872Multiple Airlines

Sat, Apr 3 - Thu, Apr 8

5:00 pm - 10:00 pmSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 00m2 stops Los Angeles Panama City Tocumen Intl

12:55 am - 6:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

20h 35m1 stop Panama City Tocumen Intl

$969Copa Airlines

Sat, Apr 3 - Fri, Apr 9

3:04 pm - 2:30 amSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

32h 26m2 stops Houston George Bush Intcntl Bogotá El Dorado

9:56 am - 11:44 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

40h 48m2 stops Panama City Tocumen Intl Los Angeles

$1,019Multiple Airlines

Mon, Apr 5 - Mon, Apr 12

3:04 pm - 2:30 amSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

32h 26m2 stops Houston George Bush Intcntl Bogotá El Dorado

9:56 am - 5:50 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

34h 54m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,019Multiple Airlines

Mon, Mar 1 - Fri, Mar 5

6:28 pm - 3:40 amSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

29h 12m3 stops San Francisco Washington, D.C. Dulles Intl Panama City Tocumen Intl

9:56 am - 8:33 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

38h 37m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$1,089United Airlines

Mon, Mar 1 - Fri, Mar 5

6:28 pm - 3:40 amSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

29h 12m3 stops San Francisco Washington, D.C. Dulles Intl Panama City Tocumen Intl

9:56 am - 9:08 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

39h 12m2 stops Panama City Tocumen Intl Denver Intl

$1,089United Airlines

Mon, Mar 1 - Fri, Mar 5

5:52 pm - 10:42 pmSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

24h 50m2 stops Los Angeles Panama City Tocumen Intl

9:56 am - 7:49 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

37h 53m2 stops Panama City Tocumen Intl Los Angeles

$1,089United Airlines

Mon, Mar 1 - Fri, Mar 5

7:41 pm - 3:40 amSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

27h 59m2 stops San Francisco Panama City Tocumen Intl

9:56 am - 9:53 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

39h 57m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,089United Airlines

Mon, Mar 1 - Fri, Mar 5

2:30 pm - 10:42 pmSAN San Diego-VVI Santa Cruz de la Sierra Viru Viru Intl

28h 12m2 stops Los Angeles Panama City Tocumen Intl

9:56 am - 9:08 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SAN San Diego

39h 12m2 stops Panama City Tocumen Intl Denver Intl

$1,089United Airlines

Booking Insights

Price, demand and travel trends for San Diego to Santa Cruz de la Sierra flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from San Diego to Santa Cruz de la Sierra? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Diego to Santa Cruz de la Sierra departing in april.

Find deals

Cheapest flight	$434

One-way flight from San Diego to Santa Cruz de la Sierra

When to book flights from San Diego to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from San Diego to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from San Diego to Santa Cruz de la Sierra?
Two cabin classes are available on flights from San Diego to Santa Cruz de la Sierra:

• Economy Class
• First Class
Do I need a passport to fly from San Diego to Santa Cruz de la Sierra?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
Have flight prices from San Diego to Santa Cruz de la Sierra changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $728 to $2,069. That means the highest observed fare was about 3x higher than the lowest one.
How are flight prices from San Diego to Santa Cruz de la Sierra looking right now?
One-way fares from San Diego to Santa Cruz de la Sierra are currently higher than usual. Average one-way flight prices are about $675, which is 41% above the typical average for this route.
Which airports can I use when flying from San Diego to Santa Cruz de la Sierra?
Flights from San Diego to Santa Cruz de la Sierra usually depart from San Diego (SAN) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).
Which airports do connecting flights from San Diego to Santa Cruz de la Sierra pass through?
Most connecting flights from San Diego to Santa Cruz de la Sierra pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.
Can I save money by using flexible dates for flights from San Diego to Santa Cruz de la Sierra?
Yes. Flexible dates can save you up to 65% on flights from San Diego to Santa Cruz de la Sierra. Tuesday is the cheapest departure day at $689 round-trip on average, while Thursday is the most expensive at $1,918, a difference of $1,229.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
What is the time difference between San Diego and Santa Cruz de la Sierra?
Santa Cruz de la Sierra is 3 hours ahead of San Diego (Bolivia Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Tuesday departure and avoid flying on Thursday. On this route, Tuesday flights average $689, about $1,229 less than Thursday fares (64% savings) based on the last 12 months.
If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Cruz de la Sierra Viru Viru Intl Airport.

• Sun Hotel

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SAN - VVI

$434 Find Cheap Flights from San Diego to Santa Cruz de la Sierra - Compare and Save

Everything you should know

Cheap Flights from San Diego to Santa Cruz de la Sierra (SAN-VVI)

Recent round-trip flight deals from San Diego to Santa Cruz de la Sierra

Recent one-way flight deals from San Diego to Santa Cruz de la Sierra

Price, demand and travel trends for San Diego to Santa Cruz de la Sierra flights

How much is a round-trip flight from San Diego to Santa Cruz de la Sierra?

Which airline is the cheapest to fly from San Diego to Santa Cruz de la Sierra?

What is the cheapest layover airport when flying from San Diego to Santa Cruz de la Sierra?

When flying from San Diego to Santa Cruz de la Sierra which airport offers the shortest layover?

Key details for San Diego to Santa Cruz de la Sierra flights

Cheapest flight

When to book flights from San Diego to Santa Cruz de la Sierra

Your San Diego to Santa Cruz de la Sierra flight questions, answered

Your guide to booking San Diego to Santa Cruz de la Sierra flights

More options for your flight from San Diego to Santa Cruz de la Sierra

Complete your trip to Santa Cruz de la Sierra with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from San Diego to Santa Cruz de la Sierra

Find direct flights to and from San Diego and Santa Cruz de la Sierra

Flights from domestic origins to Santa Cruz de la Sierra

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