$158 Find Cheap Flights from San Diego to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to South America departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from San Diego to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$657
Bogotá
Bogotá1 stop$359
Buenos Aires
Buenos Aires1 stop$738
Rio de Janeiro
Rio de Janeiro2 stops$860
Santiago
Santiago2 stops$777
Cartagena
Cartagena1 stop$467
Quito
Quito1 stop$440
Guayaquil
Guayaquil1 stop$409
Cali
Cali1 stop$479
Cusco
Cusco2 stops$718
Montevideo
Montevideo1 stop$917
Asuncion
Asuncion2 stops$1,023
Lima
Lima1 stop$657
Bogotá
Bogotá1 stop$359
Buenos Aires
Buenos Aires1 stop$738
Rio de Janeiro
Rio de Janeiro2 stops$860
Santiago
Santiago2 stops$777
Cartagena
Cartagena1 stop$467
Quito
Quito1 stop$440
Guayaquil
Guayaquil1 stop$409
Cali
Cali1 stop$479
Cusco
Cusco2 stops$718
Montevideo
Montevideo1 stop$917
Asuncion
Asuncion2 stops$1,023

Book Cheap San Diego to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Diego to South America

Thu, Jul 16 - Tue, Jul 21
Copa Airlines Logo
10:00 pm - 1:29 pm
SAN
-
BOG
13h 29m
1 stop
Copa Airlines Logo
6:17 pm - 6:30 pm
BOG
-
SAN
26h 13m
1 stop
$359Copa Airlines
Sat, Sep 19 - Tue, Sep 22
United Airlines Logo
8:00 am - 7:20 pm
SAN
-
BOG
9h 20m
1 stop
United Airlines Logo
8:30 am - 9:24 pm
BOG
-
SAN
14h 54m
1 stop
$371United Airlines
Sat, Sep 19 - Tue, Sep 22
United Airlines Logo
8:00 am - 4:54 am
SAN
-
BOG
18h 54m
1 stop
United Airlines Logo
8:30 am - 8:02 pm
BOG
-
SAN
13h 32m
2 stops
$376United Airlines
Sun, Nov 1 - Thu, Nov 5
Copa Airlines Logo
3:00 pm - 5:10 am
SAN
-
BOG
11h 10m
1 stop
Copa Airlines Logo
8:15 am - 5:50 pm
BOG
-
SAN
12h 35m
1 stop
$432Copa Airlines
Mon, Oct 12 - Sun, Nov 1
LATAM Airlines Logo
6:15 am - 10:10 pm
SAN
-
LIM
13h 55m
1 stop
LATAM Airlines Logo
12:50 am - 3:20 pm
LIM
-
SAN
17h 30m
1 stop
$657LATAM Airlines
Mon, Oct 12 - Mon, Nov 2
LATAM Airlines Logo
3:59 pm - 7:25 am
SAN
-
LIM
13h 26m
1 stop
LATAM Airlines Logo
8:15 am - 11:03 pm
LIM
-
SAN
17h 48m
2 stops
$662LATAM Airlines
Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
10:59 am - 7:05 am
SAN
-
EZE
16h 06m
1 stop
American Airlines Logo
10:35 pm - 10:38 pm
EZE
-
SAN
28h 03m
1 stop
$739American Airlines
Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
8:05 am - 7:00 am
SAN
-
EZE
18h 55m
2 stops
American Airlines Logo
9:15 am - 10:38 pm
EZE
-
SAN
17h 23m
1 stop
$743American Airlines
Tue, Oct 13 - Thu, Oct 22
Delta Logo
12:50 pm - 8:00 pm
SAN
-
GRU
27h 10m
2 stops
Delta Logo
10:50 pm - 3:41 pm
GRU
-
SAN
20h 51m
1 stop
$777Delta
Wed, Sep 23 - Mon, Oct 5
Delta Logo
6:15 am - 8:15 am
SAN
-
SCL
22h 00m
1 stop
Delta Logo
8:40 pm - 1:08 pm
SCL
-
SAN
20h 28m
1 stop
$804Delta
Booking Insights

KAYAK's insights & trends for San Diego to South America flights

Get data-powered insights and trends into flights from San Diego to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Diego to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to South America is May, when tickets cost $67 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $1,646 and $270 respectively.

How far in advance should I book a flight from San Diego to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to South America, you should book around 2 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$158
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 27% increase in price.
Flight from San Diego to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Diego to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Diego to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Diego to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Diego to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Diego to South America

 
Need help choosing which airline to fly with from San Diego to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8404 reviews
8.5Crew
7.2Food
7.8Entertainment
8.1Boarding
7.8Comfort
Airline reviews

Be on time? When not on time a circling for over an hour offer more than 1 bag of chips to the passengers? It was a 7 hour flight by the time we got done.

4.0 OkayAndrew, Jun 2026
LAX - JFK
Read more Delta reviews

Be on time? When not on time a circling for over an hour offer more than 1 bag of chips to the passengers? It was a 7 hour flight by the time we got done.

Flight delayed four separate times. I’m now one hour hours late to landing.

Checkin was good, fllight ws good. Onlly complaint is lack of foot on 6 hour flight from Seattle to Boston. Snacks were flimsy - chips and cookies. could have offered something more substantial for such a long flight. I know you can buy food in airport but for the price you pay for a ticket, they should step up for the passengers.

Long story short, it was one of the better flight experiences I've had in some time when compared with other airlines.

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

I was promised by United Airline (operated by ANA) that I will be seated together with my kids as I am the only adult flying with two minors. We did not get seats together in our 11 hours flight from LA to Tokyo. When asked at the gate, ANA representative said United Airline should have informed them that there is a parent flying with two minors. He said they can’t do anything in the system as the flight is full. He ask me to ask passengers next to me and the kids if they are willing to change seats. This is ridiculous! However, I went in the flight and asked other passages but no one willing to change seats. 11 hours and we were seating separately. I was very disappointed with this. It made things super inconvenient for me.

Service was professional and quick. Premium economy seat was comfortable given the class

It was perfect! United Airlines staff was extremely caring, super friendly and professional

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Over 2.5 hour maintenance delay on first morning flight with no acknowledgement, compensation or even gesture of good will. Aircraft had overnighted at airport so issue should have been addressed prior to boarding. Over 3.5 hours before first slow and deliberate beverage service.

United has maintenance issues and can then never recover. No operations ability and simple issues always turn into multiple hours long cascading delays. Worst airline on earth.

I paid for a confirmed upgraded aisle seat and was moved to a center seat in the back of the plane at the last minute.

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Luggage did not make it onto my plane. Business seats were economy with empty row seat. Just horrible experience. Why would the company allow for transfers that don’t give employees enough time to transfer luggages??

The gate experience at LAX was abysmal (same for the arrival experience two days prior). Despite the LAX -> SAT schedule of two flights daily, our departure gate was at a smaller hub that we had to be bussed to from Terminal 4. Fortunately, I arrived at LAX extra early and had time to spare, but if I had not known, I might have missed my flight. I looked at the LAX airport map in the AA app and there was no indication of the additional boarding process. Lastly the gate area we were bussed to was crowded with limited food and beverage options. On flight, the fight attendant was hospitable and attentive, the flight was smooth, and AA's free (and working) wifi for AA members were all on the positive side.

Our flight from JFK to Madrid was delayed. We had to go from one side of the Madrid airport (Terminal 4s to the far end of terminal 4 - Gate K98) to our gate in less than 30 minutes. Put passport control and security/baggage check and that’s very hard unless you’re Usain Bolt. I called Iberia Airlines and the telephone customer service told me that I was going to have to pay to re-book. Luckily the help desk in the airport (who was dealing with dozens of people from the same JFK-Madrid flight) did not charge us extra to reschedule to a flight 8 hours later. They also gave us a voucher for breakfast and lunch. Glad the actual person at the airport had some actual sense.

For an long range economy flight I feel more space and more meal options need to be offered for flights over 5 hours

Take-off delayed an hour because of a missing flight officer, so,arrived in Charlotte lates causing many passengers to miss connections. Otherwise a very good flight, safe and comfortable, with an excellent professional crew.

The flight from LA to Chicago was smooth and service was very good overall.

B-class on an old plane with antiquated amenities and poor service. Landed in Rome w/o bag that didn’t make the connection (plenty of time in London). Bag will come to hotel NOT the day it lands but the following night!! Still waiting for bag…BA had nothing to offer in support and couldn’t even tell me their comp, told to submit receipts and then I’ll learn what is or isn’t covered.

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

It's a long flight and that is always difficult. I was comfortable and well. The movies available were great and the crew was good.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Everything you need to know for your flight to South America

Information on your arrival and departure airports