SAN - SCL

$385 Find Cheap Flights from San Diego to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to Santiago departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$727
Typical prices: $805-$536
Copa Airlines
Mon 9/28Tue 10/6
SAN - SCL • 1 stop
Cheapest one-way
$385
Typical prices: $573-$913
Multiple Airlines
Mon 9/7
SAN - SCL • 3 stops
Top airlines
Cheapest • from $727 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between San Diego and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $834 (round-trip)
Shortest trip • 14h 30m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 35% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Diego to Santiago (SAN-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Diego to Santiago

Mon, Sep 28 - Tue, Oct 6
Copa Airlines Logo
9:03 pm - 8:32 pm
SAN
-
SCL
19h 29m
1 stop
Copa Airlines Logo
3:15 am - 6:30 pm
SCL
-
SAN
19h 15m
1 stop
$727Copa Airlines
Wed, Oct 28 - Thu, Nov 5
Delta Logo
12:50 pm - 2:05 pm
SAN
-
SCL
21h 15m
2 stops
Delta Logo
6:45 pm - 10:10 am
SCL
-
SAN
20h 25m
2 stops
$739Delta
Mon, Sep 28 - Wed, Oct 7
American Airlines Logo
11:15 am - 8:50 am
SAN
-
SCL
17h 35m
2 stops
American Airlines Logo
9:30 pm - 11:25 am
SCL
-
SAN
17h 55m
1 stop
$744American Airlines
Mon, Sep 28 - Wed, Oct 7
Delta Logo
10:46 am - 8:15 am
SAN
-
SCL
17h 29m
1 stop
Delta Logo
8:40 pm - 9:41 pm
SCL
-
SAN
29h 01m
1 stop
$745Delta
Fri, Aug 14 - Fri, Aug 21
Delta Logo
9:30 pm - 7:15 am
SAN
-
SCL
30h 45m
1 stop
Delta Logo
11:00 pm - 5:05 pm
SCL
-
SAN
21h 05m
2 stops
$749Delta
Mon, Sep 28 - Wed, Oct 7
LATAM Airlines Logo
6:15 am - 1:35 pm
SAN
-
SCL
27h 20m
2 stops
LATAM Airlines Logo
4:30 pm - 11:03 pm
SCL
-
SAN
34h 33m
2 stops
$784LATAM Airlines
Mon, Sep 28 - Wed, Oct 7
American Airlines Logo
7:15 am - 8:50 am
SAN
-
SCL
21h 35m
2 stops
American Airlines Logo
9:30 pm - 1:25 pm
SCL
-
SAN
19h 55m
2 stops
$791American Airlines
Mon, Sep 28 - Wed, Oct 7
GOL Logo
10:45 pm - 8:50 am
SAN
-
SCL
30h 05m
1 stop
GOL Logo
9:30 pm - 11:25 am
SCL
-
SAN
17h 55m
1 stop
$809GOL
Tue, Nov 17 - Mon, Nov 30
LATAM Airlines Logo
6:15 am - 5:35 am
SAN
-
SCL
18h 20m
1 stop
LATAM Airlines Logo
4:10 am - 10:55 pm
SCL
-
SAN
23h 45m
2 stops
$817LATAM Airlines
Fri, Aug 14 - Fri, Aug 21
American Airlines Logo
12:32 pm - 7:05 am
SAN
-
SCL
15h 33m
1 stop
American Airlines Logo
8:50 pm - 3:26 pm
SCL
-
SAN
21h 36m
2 stops
$822American Airlines
Booking Insights

KAYAK's insights & trends for San Diego to Santiago flights

Get data-powered insights and trends into flights from San Diego to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from San Diego to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Diego to Santiago departing in September.

What is the cheapest month to fly from San Diego to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to Santiago is September, where tickets cost $573 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is $1,258 and $1,129 respectively.

How far in advance should I book a flight from San Diego to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$385
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 42% increase in price.
Flight from San Diego to Santiago

When to book flights from San Diego to Santiago

Are your dates flexible? Find out the best times to travel from San Diego to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Diego to Santiago

  • What is the cheapest flight from San Diego to Santiago?

    In the last 5 days, the lowest price for a flight from San Diego to Santiago was $385 for a one-way ticket and $727 for a round-trip.

  • Do I need a passport to fly between San Diego and Santiago?

    Yes, you’ll need a passport to travel to Santiago from San Diego.

  • Which airports will I be using when flying from San Diego to Santiago?

    When flying out of San Diego you will be using San Diego. You will be landing at Santiago, also known as Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from San Diego to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Diego to Santiago?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between San Diego and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from San Diego to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from San Diego to Santiago are Delta and Copa Airlines. With an average price for the route of $941 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $541 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from San Diego to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to San Diego with another airline. Booking your flights between San Diego and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from San Diego to Santiago

 
See real verified KAYAK customer reviews for airlines flying from San Diego to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Diego to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8398 reviews
7.2Food
8.5Crew
8.1Boarding
7.8Comfort
7.8Entertainment
Airline reviews

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

10.0 ExcellentTeresa, Apr 2026
SMF - LAX
Read more Delta reviews

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I took seat 15A in anticipation of window seat, there is no window.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Easy of boarding, helpfully staff at check in, surprisingly comfortable seating

Lost of requested seat assignments. Lost my husband's meal choice

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

Late plane. Only one crew on the ground so we b had to wait for Denver flight to come in, board, and depart. At 78 yrs of age I was not pleased trying to get my connection. What really made me angry was the notification you sent me to hurry up or I would miss my connection. Why tell me to hurry up when you got me in late. It was not a good way of treating customers.

My flight time was changed without any notification to me which ruined my time sensitive plans so I ended up completely changing my travel plans and no reimbursement.

No screens or meal options. Freezing cold. Dirty seats. Left late.

I liked that my son and I were reseated next to each other (we had different bookings). I liked that it was a directg flight and mostly on time. I liked that you provided pillows and blankets. Flight attendants were generally courteous. The messaging through wifi did not work well. The food was not good. Seats are very narrow and I felt slightly claustraphobic in the window seat.

The flight from LA to Chicago was smooth and service was very good overall.

B-class on an old plane with antiquated amenities and poor service. Landed in Rome w/o bag that didn’t make the connection (plenty of time in London). Bag will come to hotel NOT the day it lands but the following night!! Still waiting for bag…BA had nothing to offer in support and couldn’t even tell me their comp, told to submit receipts and then I’ll learn what is or isn’t covered.

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

It's a long flight and that is always difficult. I was comfortable and well. The movies available were great and the crew was good.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

The crew was very attentive through out the flight. Seats were comfortable, nice flight bag with pillow and blanket. Food was okay, since it was a overnight flight seemed to go by fast.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Boarding gate at LAX was too crowded—two gates next to one another

On time departure and early arrival. Flight attendant very nice.

The business class layout of chairs was weired. You are sitting directly across stranger.,

Everything you need to know for your flight from San Diego to Santiago

Information on your arrival and departure airports