$381 Find Cheap Flights from San Francisco to Chile - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Chile departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Francisco to Chile

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago2 stops$645
Puerto Natales
Puerto Natales2 stops$1,022
Easter Island
Easter Island2 stops$2,557
Punta Arenas
Punta Arenas2 stops$1,043
Calama
Calama2 stops$972
Puerto Montt
Puerto Montt2 stops$1,003
Temuco
Temuco2 stops$953
Concepción
Concepción2 stops$969
La Serena
La Serena2 stops$973
Iquique
Iquique2 stops$1,003
Santiago
Santiago2 stops$645
Puerto Natales
Puerto Natales2 stops$1,022
Easter Island
Easter Island2 stops$2,557
Punta Arenas
Punta Arenas2 stops$1,043
Calama
Calama2 stops$972
Puerto Montt
Puerto Montt2 stops$1,003
Temuco
Temuco2 stops$953
Concepción
Concepción2 stops$969
La Serena
La Serena2 stops$973
Iquique
Iquique2 stops$1,003

Book Cheap San Francisco to Chile Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Chile that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Chile

Mon, Oct 26 - Wed, Nov 4
LATAM Airlines Logo
7:00 am - 4:00 am
SFO
-
SCL
17h 00m
2 stops
LATAM Airlines Logo
8:50 pm - 11:54 am
SCL
-
SFO
20h 04m
2 stops
$645LATAM Airlines
Tue, Oct 27 - Tue, Nov 10
LATAM Airlines Logo
4:15 pm - 2:05 pm
SFO
-
SCL
17h 50m
2 stops
LATAM Airlines Logo
8:50 pm - 11:54 am
SCL
-
SFO
20h 04m
2 stops
$673LATAM Airlines
Mon, Dec 7 - Sat, Dec 12
LATAM Airlines Logo
7:00 am - 4:20 am
SFO
-
SCL
16h 20m
2 stops
LATAM Airlines Logo
11:25 pm - 11:54 am
SCL
-
SFO
17h 29m
1 stop
$675LATAM Airlines
Mon, Nov 16 - Mon, Dec 14
LATAM Airlines Logo
7:30 am - 5:40 am
SFO
-
SCL
17h 10m
2 stops
LATAM Airlines Logo
8:55 pm - 11:54 am
SCL
-
SFO
19h 59m
2 stops
$679LATAM Airlines
Mon, Oct 26 - Mon, Nov 9
Copa Airlines Logo
1:31 am - 8:19 pm
SFO
-
SCL
14h 48m
1 stop
Copa Airlines Logo
1:22 am - 5:25 pm
SCL
-
SFO
21h 03m
1 stop
$692Copa Airlines
Sun, Nov 1 - Sat, Nov 7
Copa Airlines Logo
7:36 pm - 11:36 pm
SFO
-
SCL
23h 00m
1 stop
Copa Airlines Logo
5:07 am - 11:12 pm
SCL
-
SFO
23h 05m
1 stop
$715Copa Airlines
Tue, Aug 4 - Wed, Aug 12
Multiple Airlines Logo
1:12 am - 9:11 am
SFO
-
CJC
28h 59m
2 stops
Multiple Airlines Logo
7:28 pm - 10:35 pm
CJC
-
SFO
30h 07m
3 stops
$972Multiple Airlines
Wed, Aug 5 - Wed, Aug 12
Multiple Airlines Logo
8:21 pm - 7:53 am
SFO
-
CJC
32h 32m
3 stops
Multiple Airlines Logo
3:25 pm - 10:35 pm
CJC
-
SFO
34h 10m
3 stops
$1,036Multiple Airlines
Tue, Dec 22 - Tue, Dec 29
Delta Logo
6:00 am - 11:55 am
SFO
-
IPC
26h 55m
2 stops
Delta Logo
2:30 pm - 7:37 pm
IPC
-
SFO
32h 07m
2 stops
$2,976Delta
Tue, Dec 22 - Thu, Dec 31
Delta Logo
7:00 am - 11:55 am
SFO
-
IPC
25h 55m
2 stops
Delta Logo
2:30 pm - 7:37 pm
IPC
-
SFO
32h 07m
2 stops
$3,092Delta
Booking Insights

KAYAK's insights & trends for San Francisco to Chile flights

Get data-powered insights and trends into flights from San Francisco to Chile to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Francisco to Chile?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Chile, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Chile is May, when tickets cost $290 (return) on average. On the other hand, the most expensive months are June and April, when the average cost of round-trip tickets is $653 and $513 respectively.

How far in advance should I book a flight from San Francisco to Chile?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Chile, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Chile, you should book around 3 weeks before departure, which saves you about 2% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonJune
Cheapest flight$381
Most popular time to fly with an average 8% increase in price.
Flight from San Francisco to Santiago

FAQs - booking Chile flights

  • How does KAYAK find such low prices on flights from San Francisco to Chile?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Chile.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Chile?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Chile is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Chile?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Chile with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Chile?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Chile up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Francisco to Chile

 
Need help choosing which airline to fly with from San Francisco to Chile? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8456 reviews
8.1Boarding
8.5Crew
7.8Comfort
7.8Entertainment
7.2Food
Airline reviews

Flight delayed four separate times. I’m now one hour hours late to landing.

2.0 MediocreTravis, Jun 2026
SFO - LAX
Read more Delta reviews

Flight delayed four separate times. I’m now one hour hours late to landing.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

New boarding doesn't make sense. Filling front first is slow.

There was plenty of overhead room but half of the passengers were told they had to check their carryon bags. My partner and I checked in as early as possible and our seats were split across the aisle.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was good, plane is a bit older so seats are somewhat flat

Very good flight and crew Food was a surprise on a short flight

Biggest issue was that they only had two restrooms in the back of the aircraft. Too many people for only two restrooms. The trash was overflowing and there was paper on the floor too. Long lines in the isle to use it. Food was also a bit meh. They don’t offer snacks with drinks, so you might want to buy a snack to hold you off on a longer trip, since the meals are very small.

Everything was smooth and crew was very polite and friendly.

I like that they served a mail, I’m not sure about the in-flight entertainment. I didn’t really check. staff helped me with my luggage. Smooth boarding smooth takeoff smooth flight

The seats had plenty of leg room and the staff were very nice.

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

Routine and on time flight with pleasant stewards and decent food. Nice experience!

The crew was amazing. The best in the last times. Great group of people.

You delayed my trip three days for no reason other than your lack of preparedness, did not offer any compensation, including food or a bed. I couldn’t trust you so I moved up my return flight and lost another day at the end of my trip to hopefully make sure I make my next flight. I will never fly LATAM again. You have the worse accountability and reliability and clearly do not care that your clients have lives and what it cost to fly to another country.

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

It was a good experience, the flight was a little too long & the food was ok

No extra snacks were available. Meals quality is terrible. Crew was not friendly.

Lost one piece of luggage even though I checked in 2.5 hours before the flight

It was perfect! United Airlines staff was extremely caring, super friendly and professional

United has maintenance issues and can then never recover. No operations ability and simple issues always turn into multiple hours long cascading delays. Worst airline on earth.

I paid for a confirmed upgraded aisle seat and was moved to a center seat in the back of the plane at the last minute.

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Easy of boarding, helpfully staff at check in, surprisingly comfortable seating

Lost of requested seat assignments. Lost my husband's meal choice

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

My flight time was changed without any notification to me which ruined my time sensitive plans so I ended up completely changing my travel plans and no reimbursement.

Flight was delayed multiple times without giving any particular reason and the only thing that was communicated was that 'Aircraft is getting ready'. I was stuck at SFO airport for 15 hours and finally took Southwest Airlines flight back home to Dallas.

I was not clear if food was offered or not.

Agency very bad had to cancelled my booking too many changes in the flight changed my flight to 1 week

Take-off delayed an hour because of a missing flight officer, so,arrived in Charlotte lates causing many passengers to miss connections. Otherwise a very good flight, safe and comfortable, with an excellent professional crew.

B-class on an old plane with antiquated amenities and poor service. Landed in Rome w/o bag that didn’t make the connection (plenty of time in London). Bag will come to hotel NOT the day it lands but the following night!! Still waiting for bag…BA had nothing to offer in support and couldn’t even tell me their comp, told to submit receipts and then I’ll learn what is or isn’t covered.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

The SFO Lounge crew were amazing. The bartender Faris was great. Thanks!

Not good. One of my luggage is missing. And until now they can’t find it

Flight attendants were kind and courteous. We were a delayed due to the incoming flight; but we made it safe which is what matters. Thanks!

Dloght delayed by 2.5 hrs . Common theme in my last four american floghts

Everything you need to know for your flight from San Francisco to Chile

Information on your arrival and departure airports