SFO - SCL

$200 Find Cheap Flights from San Francisco to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
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Everything you should know

Cheapest round-trip
$576
Overall average: $754
Avianca
Sun 10/19Fri 11/7
SFO - SCL • 2 stops
Cheapest one-way
$200
Typical prices: $390-473
Avianca
Tue 10/21
SFO - SCL • 2 stops
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Top airlines
Avianca
Cheapest • from $576 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
August
Cheapest • 15% price drop
December
Most popular
Good to know
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+1
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Francisco to Santiago (SFO-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santiago

Sun, Oct 19 - Fri, Nov 7
Avianca Logo
12:05 am - 5:15 amSFO-SCL
25h 10m2 stops
Avianca Logo
4:25 pm - 11:20 pmSCL-SFO
35h 55m2 stops
$576Avianca
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Fri, Oct 31 - Fri, Nov 7
American Airlines Logo
10:20 am - 8:55 amSFO-SCL
18h 35m2 stops
American Airlines Logo
11:15 pm - 1:37 pmSCL-SFO
19h 22m1 stop
$579American Airlines
Find Deal
Tue, Oct 21 - Fri, Nov 7
LATAM Airlines Logo
7:15 am - 7:00 amSFO-SCL
19h 45m1 stop
LATAM Airlines Logo
11:35 pm - 9:45 amSCL-SFO
15h 10m1 stop
$582LATAM Airlines
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Sat, Nov 22 - Fri, Dec 5
United Airlines Logo
7:10 pm - 8:50 amSFO-SCL
32h 40m1 stop
United Airlines Logo
10:45 pm - 12:09 pmSCL-SFO
18h 24m1 stop
$584United Airlines
Find Deal
Thu, Jan 22 - Mon, Feb 2
LATAM Airlines Logo
6:00 am - 5:35 amSFO-SCL
18h 35m2 stops
LATAM Airlines Logo
11:15 pm - 10:36 amSCL-SFO
16h 21m1 stop
$587LATAM Airlines
Find Deal
Sun, Oct 19 - Fri, Nov 7
Copa Airlines Logo
1:31 am - 8:20 pmSFO-SCL
14h 49m1 stop
Copa Airlines Logo
5:24 am - 11:17 pmSCL-SFO
22h 53m1 stop
$592Copa Airlines
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Tue, Jan 20 - Fri, Feb 6
United Airlines Logo
12:43 am - 8:50 amSFO-SCL
27h 07m1 stop
United Airlines Logo
10:45 pm - 4:50 pmSCL-SFO
23h 05m1 stop
$593United Airlines
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Thu, Oct 30 - Thu, Nov 6
Delta Logo
11:58 am - 7:40 amSFO-SCL
15h 42m1 stop
Delta Logo
4:35 am - 9:57 pmSCL-SFO
22h 22m2 stops
$594Delta
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Fri, Oct 31 - Wed, Nov 5
Delta Logo
6:10 am - 7:00 amSFO-SCL
20h 50m2 stops
Delta Logo
12:50 am - 6:56 pmSCL-SFO
23h 06m2 stops
$599Delta
Find Deal
Mon, Nov 3 - Tue, Nov 11
Copa Airlines Logo
12:36 am - 6:01 amSFO-SCL
24h 25m1 stop
Copa Airlines Logo
12:20 pm - 11:17 pmSCL-SFO
15h 57m1 stop
$602Copa Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for San Francisco to Santiago flights

Get data-powered insights and trends into flights from San Francisco to Santiago to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Santiago
Find cheap flights to Santiago

Planning a trip from San Francisco to Santiago? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

What’s the cheapest day of the week to fly from San Francisco to Santiago?

The average price of all round-trip flights from San Francisco to Santiago clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santiago on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from San Francisco to Santiago. For your return ticket, we recommend flying on a Saturday and avoiding Mondays for the best deals.

What is the cheapest month to fly from San Francisco to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Santiago is August, where tickets cost $708 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $1,239 and $914 respectively.

How far in advance should I book a flight from San Francisco to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$200
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 49% increase in price.
Flight from San Francisco to Santiago

When to book flights from San Francisco to Santiago

Are your dates flexible? Find out the best times to travel from San Francisco to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Santiago

  • Do I need a visa to fly from San Francisco to Santiago?

    A visa is not one of the mandatory requirements for US citizens traveling to Chile as long as the trip doesn’t exceed 90 days. If so, you will have to visit the Chilean Embassy for further inquiry. You will also need your passport which should be valid up to the point of planned departure from Chile.

  • Which airlines fly directly from San Francisco to Santiago?

    At the moment, there aren’t any airlines flying directly from San Francisco to the city center. Travelers will have to deal with at least one layover during the trip. The most popular layover option for this trip is Los Angeles International Airport which is used by Delta and LATAM Airlines. Other options include Houston when flying with United Airlines and Panama City when flying with Copa Airlines.

  • Is public transport available from Santiago International Airport to the city center?

    The only public transport option available from Santiago International Airport to the city center is the bus service. It runs 24/7 at intervals of 20 minutes during the day and an hour after midnight. The bus connects Santiago Airport to Santiago Central Station although you can disembark at any of the prior stops if it is convenient for you. An alternative to using the bus is getting a taxi from the airport. Although more expensive, it is significantly more convenient and safer than public transport.

  • With which airline should I book a solo ticket for my child?

    LATAM Airlines has an unaccompanied minor service that allows children to fly unaccompanied on international flights. The service is mandatory for children between ages 8 and 12 and only optional for children older than that. With this service, you as the parent can have confidence in the safety of your child as they will have a crew member looking after your child for the whole trip including through immigration and security control.

  • What is the cheapest flight from San Francisco to Santiago?

    In the last 3 days, the lowest price for a flight from San Francisco to Santiago was $200 for a one-way ticket and $576 for a round-trip.

  • Do I need a passport to fly between San Francisco and Santiago?

    Yes

  • Which airports will I be using when flying from San Francisco to Santiago?

    San Francisco and Santiago are both served by 1 main airport. You will leave San Francisco from San Francisco and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from San Francisco to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Francisco to Santiago?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between San Francisco and Santiago, with oneworld being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from San Francisco?

    Los Angeles is the most popular layover city among KAYAK users traveling from San Francisco to Santiago.

  • Which is the best airline for flights from San Francisco to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Santiago are Delta and Copa Airlines. With an average price for the route of $836 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $731 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from San Francisco to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from San Francisco to Santiago

  • San Jose Mineta International Airport (SJC) is an alternative for anyone looking for a different departure airport to San Francisco International Airport (SFO). The airport is about 40 miles away from the Bay area and is less busy compared to SFO meaning shorter queues.
  • If you’re looking for a sustainable airline to fly from San Francisco to Santiago (SCL), Delta Air Lines is a great option. They recently invested close to $1 billion over the next decade towards projects that reduce carbon emissions and advance clean air technologies.
  • When booking an economy class ticket with Delta, the main cabin option comes with more privileges. You get the option of advanced seat selection and you are eligible for an upgrade to first class by adding a small charge instead of paying the full amount for First class tickets.
  • LATAM Airlines offers a lot more amenities on its economy cabin compared to any other airline serving the route. They have free Wi-Fi, power outlets, seatback on-demand TV, and a free snack for your flight.
  • The Bay Area Rapid Transit offers a great commuter option to San Francisco International Airport from downtown San Fran. It is especially convenient when Bay Area traffic is a big problem during rush hours.

Reviews of the top 5 airlines serving from San Francisco to Santiago

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7967 reviews
7.9Comfort
7.9Entertainment
7.3Food
8.5Crew
8.2Boarding
Airline reviews

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

2.0 MediocreAnonymous, Sep 2025SNA - SEA
Read more Delta reviews

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

Crew was excellent. Comfort seats not as nice as other kinds of planes.

It was a great flight and the stewards and stewardess were all kind and accommodating!! The seats were comfortable and entertainment screen excellent!

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

There was a security issue at the airport and we were unable to land. We circled endlessly and then landed at another airfield for fuel. We then circled the airport again, almost landed but didn’t fully touch down before circling again. I am thankful to the crew for keeping us safe- the issue was the airline and staff at the airport getting us seats on our connecting flights. That part was hours of searching for someone and getting in double my steps.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

It was ok. However, the food was quite poor since I don't eat pasta.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

From the first moment you interact with United Airlines, you can expect nothing less but extreme frustration. The baggage handler at the bag drop seems completely unbothered by the presence of customers waiting in line. No help was extended to load the baggage whatsoever. And if any of your bags is overweight by 0.01 pound they will make you re-distribute everything in your suitcase just to play power trip. When it was time to board no help was extended to customers to locate their seats. Moreover. It was a chaotic mess at the gate when it was unclear who should board first and everyone just bunched up, trying to get on the plane. I am sure the crew was doing their best to perform their jobs while being paid their wages however it shouldn’t be that hard to smile once or twice when you’re in the business if serving customers. It is a shame for the United States of America to have a flagship carrier of such low caliber. Our flight was also delayed by about an hour and a half due to further delays prior to our inbound flight. Being someone who has travelled for both business and leisure in Asia, Europe, and South America I have never experienced such poor quality of service.

The pilots were late and it made us 1 hour late. The meat was tough and bok choy was also tough.

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

The best airline I have ever travel , really good customer service, attention and service !!

Everything was great. Only thing that could’ve made it better was buy on board options for hot food, but the snacks were decent. The flight attendants were great. I had no complaints. I was able to make it to my destination safely

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Flight was late as pilot crew had to land at different airport in their previous flight. Passengers boarded and had to wait for pilots inside plane. Series of incomplete and unnecessary announcements by an annoying voice, rather than complete, informative announcements.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

Very crowded flight but what can you expect these days?? Crew was accommodating.

The seats in economy were appeared to be quite thin and lack sufficient cushioning to be comfortable. Perhaps it was my seating position but the plane seemed notably load.

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Was not able to watch most shows on the entertainment site. They would not load

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Delayed flight, so I switched fights to SFO to Phoenix , Phoenix to DSM. Excellent service through American Airlines

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