SFO - SCL

$350 Find Cheap Flights from San Francisco to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
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Everything you should know

Cheapest round-trip
$696
Typical prices: $853-$651
Multiple Airlines
Mon 5/4Mon 5/11
SFO - SCL • 3 stops
Cheapest one-way
$350
Typical prices: $296-$429
Multiple Airlines
Mon 5/4
SFO - SCL • 3 stops
Top airlines
Cheapest • from $703 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between San Francisco and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $936 (round-trip)
Shortest trip • 14h 38m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 6% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 15% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Francisco to Santiago (SFO-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santiago

Mon, May 4 - Mon, May 11
Multiple Airlines Logo
11:55 pm - 3:56 am
SFO
-
SCL
25h 01m
3 stops
Multiple Airlines Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
$696Multiple Airlines
Tue, Sep 1 - Wed, Sep 30
LATAM Airlines Logo
7:00 am - 5:35 am
SFO
-
SCL
19h 35m
1 stop
LATAM Airlines Logo
11:25 pm - 11:59 am
SCL
-
SFO
16h 34m
1 stop
$703LATAM Airlines
Sun, May 3 - Sun, May 10
Multiple Airlines Logo
2:15 pm - 1:30 pm
SFO
-
SCL
20h 15m
2 stops
Multiple Airlines Logo
3:20 pm - 12:50 pm
SCL
-
SFO
24h 30m
2 stops
$717Multiple Airlines
Mon, Aug 10 - Mon, Aug 17
Multiple Airlines Logo
8:43 pm - 5:35 am
SFO
-
SCL
29h 52m
1 stop
Multiple Airlines Logo
11:25 pm - 11:27 am
SCL
-
SFO
15h 02m
1 stop
$718Multiple Airlines
Sun, Jul 12 - Mon, Jul 20
LATAM Airlines Logo
11:50 am - 5:35 am
SFO
-
SCL
14h 45m
1 stop
LATAM Airlines Logo
11:25 pm - 10:49 am
SCL
-
SFO
14h 24m
1 stop
$720LATAM Airlines
Sat, May 2 - Sun, May 10
Multiple Airlines Logo
2:30 am - 5:30 am
SFO
-
SCL
24h 00m
3 stops
Multiple Airlines Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
$721Multiple Airlines
Tue, May 12 - Sat, May 16
Multiple Airlines Logo
2:30 am - 1:30 pm
SFO
-
SCL
32h 00m
2 stops
Multiple Airlines Logo
3:20 pm - 10:35 pm
SCL
-
SFO
34h 15m
2 stops
$723Multiple Airlines
Tue, Sep 1 - Wed, Sep 30
LATAM Airlines Logo
6:00 am - 5:35 am
SFO
-
SCL
20h 35m
2 stops
LATAM Airlines Logo
11:25 pm - 11:59 am
SCL
-
SFO
16h 34m
1 stop
$724LATAM Airlines
Mon, May 4 - Tue, May 19
Multiple Airlines Logo
11:55 pm - 3:56 am
SFO
-
SCL
25h 01m
3 stops
Multiple Airlines Logo
6:40 am - 10:35 pm
SCL
-
SFO
42h 55m
2 stops
$725Multiple Airlines
Mon, May 4 - Thu, May 7
Multiple Airlines Logo
11:55 pm - 3:56 am
SFO
-
SCL
25h 01m
3 stops
Multiple Airlines Logo
3:20 pm - 10:35 pm
SCL
-
SFO
34h 15m
2 stops
$726Multiple Airlines
Booking Insights

KAYAK's insights & trends for San Francisco to Santiago flights

Get data-powered insights and trends into flights from San Francisco to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from San Francisco to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Francisco to Santiago departing in May.

What is the cheapest month to fly from San Francisco to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Santiago is January, where tickets cost $666 (return) on average. On the other hand, the most expensive months are April and December, where the average cost of round-trip tickets is $906 and $899 respectively.

How far in advance should I book a flight from San Francisco to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Santiago, you should book around 4 weeks before departure, which saves you about 6% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$350
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from San Francisco to Santiago

When to book flights from San Francisco to Santiago

Are your dates flexible? Find out the best times to travel from San Francisco to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Santiago

  • What is the cheapest flight from San Francisco to Santiago?

    In the last 3 days, the lowest price for a flight from San Francisco to Santiago was $350 for a one-way ticket and $696 for a round-trip.

  • Do I need a passport to fly between San Francisco and Santiago?

    Yes

  • Which airports will I be using when flying from San Francisco to Santiago?

    San Francisco and Santiago are both served by 1 main airport. You will leave San Francisco from San Francisco and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from San Francisco to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Francisco to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between San Francisco and Santiago, with SkyTeam being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from San Francisco?

    Houston is the most popular layover city among KAYAK users traveling from San Francisco to Santiago.

  • Which is the best airline for flights from San Francisco to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Santiago are Delta and Copa Airlines. With an average price for the route of $835 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $770 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from San Francisco to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Francisco to Santiago

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8402 reviews
8.1Boarding
7.9Comfort
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

10.0 ExcellentSarah, Apr 2026
LAX - SFO
Read more Delta reviews

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I took seat 15A in anticipation of window seat, there is no window.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Copa staff at PTY and one particular crew member were unhelpful & rude.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

the entire flight felt off. The crew seemed uninterested and disengaged. The food service was really bad - overcooked, bland, weird food service. They actually woke us up to serve chicken wraps in the middle of the night, after dinner and before breakfast. Made no sense. Ultimately, I was glad they did though, because the breakfast had been held for so long it was inedible. Eggs, potatoes, sausage - all disgusting. We were asked to "honor" the lavatories for premium customers and stay in our own cabin: this was also strange. So people in economy didn't pay enough to use the closest toilet to them??? It's a toilet. All in all, not the experience I have come to expect from United Airlines. The return flight from Paris to SFO was better, btw.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

it was a very short flight so my expectations were low.

Good flight, seated and had a water within 5 minutes. Crew was hospitable.

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

I cancelled my ticket less than 24 hours deadline but I didn’t get refunded.

Flight boarded from Gate 159B, the farthest gate in the LAX Bradley Terminal. While the flight operated on time, the first class cabin attendant made no recognition of my being an Advantage Executive Platinum member.

The flight itself was excellent but the gate attendant made me check my carryon since she said it was an inch too big. I’ve had no problems with this carryon on recent flights on Qantas, Delta, Austrian, Southwest Airlines even though the overhead bins are the same size. there were other carryons in the bins that also looked larger than mine and there was room left in the bins for more. When I picked up my carryon from baggage claim one of the wheels had broken off.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Everything you need to know for your flight from San Francisco to Santiago

Information on your arrival and departure airports