SFO - SCL

$320 Find Cheap Flights from San Francisco to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
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Cheap Flights from San Francisco to Santiago (SFO-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santiago

Wed, Nov 5 - Wed, Nov 12
LATAM Airlines Logo
7:30 am - 7:00 amSFO-SCL
18h 30m2 stops
LATAM Airlines Logo
8:20 am - 11:13 pmSCL-SFO
19h 53m2 stops
$585LATAM Airlines
Find Deal
Fri, Aug 22 - Mon, Aug 25
LATAM Airlines Logo
5:55 am - 4:45 amSFO-SCL
19h 50m2 stops
LATAM Airlines Logo
7:50 am - 10:09 pmSCL-SFO
17h 19m2 stops
$591LATAM Airlines
Find Deal
Mon, Sep 8 - Tue, Sep 23
Delta Logo
10:55 am - 6:00 amSFO-SCL
15h 05m1 stop
Delta Logo
5:55 pm - 11:45 amSCL-SFO
21h 50m2 stops
$615Delta
Find Deal
Wed, Sep 10 - Wed, Sep 24
Delta Logo
7:29 am - 7:00 amSFO-SCL
19h 31m1 stop
Delta Logo
9:40 pm - 10:16 amSCL-SFO
16h 36m1 stop
$624Delta
Find Deal
Tue, Sep 9 - Wed, Sep 24
Copa Airlines Logo
1:30 am - 8:20 pmSFO-SCL
14h 50m1 stop
Copa Airlines Logo
5:22 am - 11:39 pmSCL-SFO
22h 17m1 stop
$629Copa Airlines
Find Deal
Wed, Sep 10 - Thu, Sep 18
Copa Airlines Logo
1:30 am - 3:42 amSFO-SCL
22h 12m1 stop
Copa Airlines Logo
5:11 am - 11:39 pmSCL-SFO
22h 28m1 stop
$644Copa Airlines
Find Deal
Sat, Nov 1 - Thu, Nov 13
American Airlines Logo
10:45 am - 7:50 amSFO-SCL
17h 05m2 stops
American Airlines Logo
10:15 pm - 3:25 pmSCL-SFO
22h 10m2 stops
$653American Airlines
Find Deal
Thu, Aug 21 - Wed, Sep 3
Avianca Logo
12:05 am - 10:30 pmSFO-SCL
19h 25m2 stops
Avianca Logo
6:10 am - 10:45 pmSCL-SFO
19h 35m2 stops
$658Avianca
Find Deal
Fri, Oct 31 - Thu, Nov 13
American Airlines Logo
12:50 am - 7:50 amSFO-SCL
27h 00m1 stop
American Airlines Logo
10:15 pm - 11:51 amSCL-SFO
18h 36m1 stop
$659American Airlines
Find Deal
Fri, Aug 22 - Wed, Sep 10
Avianca Logo
2:20 pm - 1:25 pmSFO-SCL
20h 05m2 stops
Avianca Logo
3:30 pm - 10:45 pmSCL-SFO
35h 15m2 stops
$668Avianca
Find Deal
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KAYAK's insights & trends for San Francisco to Santiago flights

Get data-powered insights and trends into flights from San Francisco to Santiago to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Santiago
Find cheap flights to Santiago

Planning a trip from San Francisco to Santiago? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

How much is a round-trip flight from San Francisco to Santiago?

What’s the cheapest day of the week to fly from San Francisco to Santiago?

The average price of all round-trip flights from San Francisco to Santiago clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santiago on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from San Francisco to Santiago. For your return ticket, we recommend flying on a Saturday and avoiding Mondays for the best deals.

What is the cheapest month to fly from San Francisco to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Santiago is August, where tickets cost $700 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $1,321 and $892 respectively.

How far in advance should I book a flight from San Francisco to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonMay
High seasonDecember
Cheapest flight$320
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 57% increase in price.
Flight from San Francisco to Santiago

When to book flights from San Francisco to Santiago

Are your dates flexible? Find out the best times to travel from San Francisco to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Santiago

  • Do I need a visa to fly from San Francisco to Santiago?

    A visa is not one of the mandatory requirements for US citizens traveling to Chile as long as the trip doesn’t exceed 90 days. If so, you will have to visit the Chilean Embassy for further inquiry. You will also need your passport which should be valid up to the point of planned departure from Chile.

  • Which airlines fly directly from San Francisco to Santiago?

    At the moment, there aren’t any airlines flying directly from San Francisco to the city center. Travelers will have to deal with at least one layover during the trip. The most popular layover option for this trip is Los Angeles International Airport which is used by Delta and LATAM Airlines. Other options include Houston when flying with United Airlines and Panama City when flying with Copa Airlines.

  • Is public transport available from Santiago International Airport to the city center?

    The only public transport option available from Santiago International Airport to the city center is the bus service. It runs 24/7 at intervals of 20 minutes during the day and an hour after midnight. The bus connects Santiago Airport to Santiago Central Station although you can disembark at any of the prior stops if it is convenient for you. An alternative to using the bus is getting a taxi from the airport. Although more expensive, it is significantly more convenient and safer than public transport.

  • With which airline should I book a solo ticket for my child?

    LATAM Airlines has an unaccompanied minor service that allows children to fly unaccompanied on international flights. The service is mandatory for children between ages 8 and 12 and only optional for children older than that. With this service, you as the parent can have confidence in the safety of your child as they will have a crew member looking after your child for the whole trip including through immigration and security control.

  • What is the cheapest flight from San Francisco to Santiago?

    In the last 3 days, the lowest price for a flight from San Francisco to Santiago was $320 for a one-way ticket and $585 for a round-trip.

  • Do I need a passport to fly between San Francisco and Santiago?

    Yes

  • Which airports will I be using when flying from San Francisco to Santiago?

    San Francisco and Santiago are both served by 1 main airport. You will leave San Francisco from San Francisco and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from San Francisco to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Francisco to Santiago?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between San Francisco and Santiago, with Star Alliance being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from San Francisco?

    Los Angeles is the most popular layover city among KAYAK users traveling from San Francisco to Santiago.

  • Which is the best airline for flights from San Francisco to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Santiago are Delta and LATAM Airlines. With an average price for the route of $824 and an overall rating of 8.0, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $889 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from San Francisco to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from San Francisco to Santiago

  • San Jose Mineta International Airport (SJC) is an alternative for anyone looking for a different departure airport to San Francisco International Airport (SFO). The airport is about 40 miles away from the Bay area and is less busy compared to SFO meaning shorter queues.
  • If you’re looking for a sustainable airline to fly from San Francisco to Santiago (SCL), Delta Air Lines is a great option. They recently invested close to $1 billion over the next decade towards projects that reduce carbon emissions and advance clean air technologies.
  • When booking an economy class ticket with Delta, the main cabin option comes with more privileges. You get the option of advanced seat selection and you are eligible for an upgrade to first class by adding a small charge instead of paying the full amount for First class tickets.
  • LATAM Airlines offers a lot more amenities on its economy cabin compared to any other airline serving the route. They have free Wi-Fi, power outlets, seatback on-demand TV, and a free snack for your flight.
  • The Bay Area Rapid Transit offers a great commuter option to San Francisco International Airport from downtown San Fran. It is especially convenient when Bay Area traffic is a big problem during rush hours.

Reviews of the top 5 airlines serving from San Francisco to Santiago

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7983 reviews
8.5Crew
7.3Food
7.9Entertainment
7.9Comfort
8.2Boarding
Airline reviews

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

4.0 OkayMrs., Jul 2025LAX - RDU
Read more Delta reviews

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

Crew was excellent. Comfort seats not as nice as other kinds of planes.

It was a great flight and the stewards and stewardess were all kind and accommodating!! The seats were comfortable and entertainment screen excellent!

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

There was a security issue at the airport and we were unable to land. We circled endlessly and then landed at another airfield for fuel. We then circled the airport again, almost landed but didn’t fully touch down before circling again. I am thankful to the crew for keeping us safe- the issue was the airline and staff at the airport getting us seats on our connecting flights. That part was hours of searching for someone and getting in double my steps.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Delta flight was on time, seats were comfortable, and crew was nice.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

entertainment was not good; the shoulder strap on Business class seat did not sit well across the body (more like across the neck); the food was not hot and the special meal promoted by insert in the menu was not available to us

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

The flight was delayed about 4 hours without any explanation. No wifi or entertainment at all on planes. Had to pay for checked bags I was allowed according to reservations.

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Flight was late as pilot crew had to land at different airport in their previous flight. Passengers boarded and had to wait for pilots inside plane. Series of incomplete and unnecessary announcements by an annoying voice, rather than complete, informative announcements.

Breakfast was not loaded at SFO due to catering company change. Seems like a major airline at a major hub would have thought of something else or warned passengers to pick up food before boarding a 3 hour flight.

Boarding seemed to be organized bedlam. For what ever reason, preboarding took longer than 20 minutes. Made the plane 20 minutes late taking off. Luckily we arrived on time. Flight crew seemed very friendly. Only slight turbulence.

They hired a new catering company the same day of my flight. They botched the job by not delivering the right carts and after THREE HOURS waiting, the flight crew timed out (flight was 19 hours long and FAA rules state crew can’t work more than 14 hours long). So they CANCELED OUR FLIGHT!! Worst experience ever. Avoid UAL at all costs.

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

get E+, a must for 5 hours flight if you are tall

Liked fold flat bed. Didn’t like having no window. Didn’t like poor choice of food and being served dinner very late, hours after take off of a 7:40pm flight. Servers not friendly. Food horrible in business class.

AA re-routed flight from HNL to LAX due to delay. My group of 3 with reserved seats in row 9 was broken up, with one assigned to a middle seat, another in the last row of the plane. Not happy. No explanation to the delay. No apologies. No compensation. Would have been nice to be offered an Admiral Club admission or a voucher for the extra 3 hours of layover in LAX. Could not hear the boarding gate announcements in LAX. Adjacent gate was boarding at the same time. Loud speakers were competing against each other. Barely made my boarding group.

Almost a 6 hour flight and the only food option is a cheese plate… and chips. Also how is it there are no options for texting on American. I’ll be going back to delta and united.

Bad food, small seats that didn’t recline. I thought I was buying a quantas ticket so I feel like I got scammed

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

Cramped seats. FAA should make airlines have more legroom, for even short people complain

Flight was full, and would have preferred an aisle seat, but due to getting a late ticket ,the seat I had was adequate. The flight crew were very help full and hard working. Food and drink were excellent for the 11hr flight. Overall I was pleased with flight, and would recommend British Airways again.

Eventless. It was a good flight and good crew. Can’t complaint.

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

British Airways staff are very polite and willing to help.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

Everything you need to know for your flight from San Francisco to Santiago

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