SFO - SCL

$305 Find Cheap Flights from San Francisco to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santiago.
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Cheap Flights from San Francisco to Santiago (SFO-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santiago

Thu, Jul 10 - Thu, Jul 24
Avianca Logo
2:20 pm - 1:25 pmSFO-SCL
20h 05m2 stops
Avianca Logo
2:30 pm - 12:35 pmSCL-SFO
25h 05m2 stops
$586Avianca
Find Deal
Mon, Jun 9 - Wed, Jul 9
Avianca Logo
2:20 pm - 10:30 pmSFO-SCL
29h 10m2 stops
Avianca Logo
11:55 pm - 10:45 pmSCL-SFO
25h 50m2 stops
$593Avianca
Find Deal
Tue, Aug 19 - Tue, Aug 26
LATAM Airlines Logo
12:30 pm - 6:00 amSFO-SCL
14h 30m1 stop
LATAM Airlines Logo
10:45 pm - 10:00 amSCL-SFO
14h 15m1 stop
$637LATAM Airlines
Find Deal
Mon, Aug 18 - Tue, Aug 26
Copa Airlines Logo
1:28 am - 7:24 pmSFO-SCL
14h 56m1 stop
Copa Airlines Logo
4:10 am - 11:40 pmSCL-SFO
22h 30m1 stop
$652Copa Airlines
Find Deal
Tue, Aug 19 - Tue, Aug 26
LATAM Airlines Logo
12:30 pm - 6:00 amSFO-SCL
14h 30m1 stop
LATAM Airlines Logo
7:45 am - 10:09 pmSCL-SFO
17h 24m2 stops
$662LATAM Airlines
Find Deal
Thu, Jul 10 - Thu, Jul 24
Delta Logo
7:45 am - 6:45 amSFO-SCL
20h 00m2 stops
Delta Logo
10:45 pm - 10:00 amSCL-SFO
14h 15m1 stop
$668Delta
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Sat, Sep 27 - Sat, Oct 4
Copa Airlines Logo
1:28 am - 6:00 amSFO-SCL
24h 32m1 stop
Copa Airlines Logo
5:10 am - 11:40 pmSCL-SFO
22h 30m1 stop
$672Copa Airlines
Find Deal
Sun, Nov 2 - Thu, Nov 13
American Airlines Logo
11:59 pm - 7:50 amSFO-SCL
26h 51m1 stop
American Airlines Logo
11:45 pm - 3:25 pmSCL-SFO
20h 40m2 stops
$678American Airlines
Find Deal
Fri, Nov 7 - Wed, Nov 19
Delta Logo
6:00 am - 6:55 amSFO-SCL
19h 55m2 stops
Delta Logo
8:10 am - 12:16 amSCL-SFO
21h 06m2 stops
$693Delta
Find Deal
Fri, Oct 31 - Thu, Nov 13
American Airlines Logo
12:47 am - 7:50 amSFO-SCL
27h 03m1 stop
American Airlines Logo
11:45 pm - 10:00 amSCL-SFO
15h 15m1 stop
$770American Airlines
Find Deal
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KAYAK's insights & trends for San Francisco to Santiago flights

Get data-powered insights and trends into flights from San Francisco to Santiago to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Santiago
Find cheap flights to Santiago

Planning a trip from San Francisco to Santiago? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

What’s the cheapest day of the week to fly from San Francisco to Santiago?

The average price of all round-trip flights from San Francisco to Santiago clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santiago on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from San Francisco to Santiago. For your return ticket, we recommend flying on a Saturday and avoiding Mondays for the best deals.

What is the cheapest month to fly from San Francisco to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Santiago is May, where tickets cost $710 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $1,332 and $952 respectively.

How far in advance should I book a flight from San Francisco to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonMay
High seasonDecember
Cheapest flight$305
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 55% increase in price.
Flight from San Francisco to Santiago

When to book flights from San Francisco to Santiago

Are your dates flexible? Find out the best times to travel from San Francisco to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Santiago

  • Do I need a visa to fly from San Francisco to Santiago?

    A visa is not one of the mandatory requirements for US citizens traveling to Chile as long as the trip doesn’t exceed 90 days. If so, you will have to visit the Chilean Embassy for further inquiry. You will also need your passport which should be valid up to the point of planned departure from Chile.

  • Which airlines fly directly from San Francisco to Santiago?

    At the moment, there aren’t any airlines flying directly from San Francisco to the city center. Travelers will have to deal with at least one layover during the trip. The most popular layover option for this trip is Los Angeles International Airport which is used by Delta and LATAM Airlines. Other options include Houston when flying with United Airlines and Panama City when flying with Copa Airlines.

  • Is public transport available from Santiago International Airport to the city center?

    The only public transport option available from Santiago International Airport to the city center is the bus service. It runs 24/7 at intervals of 20 minutes during the day and an hour after midnight. The bus connects Santiago Airport to Santiago Central Station although you can disembark at any of the prior stops if it is convenient for you. An alternative to using the bus is getting a taxi from the airport. Although more expensive, it is significantly more convenient and safer than public transport.

  • With which airline should I book a solo ticket for my child?

    LATAM Airlines has an unaccompanied minor service that allows children to fly unaccompanied on international flights. The service is mandatory for children between ages 8 and 12 and only optional for children older than that. With this service, you as the parent can have confidence in the safety of your child as they will have a crew member looking after your child for the whole trip including through immigration and security control.

  • What is the cheapest flight from San Francisco to Santiago?

    In the last 3 days, the lowest price for a flight from San Francisco to Santiago was $305 for a one-way ticket and $586 for a round-trip.

  • Do I need a passport to fly between San Francisco and Santiago?

    Yes

  • Which airports will I be using when flying from San Francisco to Santiago?

    San Francisco and Santiago are both served by 1 main airport. You will leave San Francisco from San Francisco and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from San Francisco to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Francisco to Santiago?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between San Francisco and Santiago, with Star Alliance being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from San Francisco?

    Los Angeles is the most popular layover city among KAYAK users traveling from San Francisco to Santiago.

  • Which is the best airline for flights from San Francisco to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Santiago are Delta and LATAM Airlines. With an average price for the route of $838 and an overall rating of 8.0, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $905 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from San Francisco to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from San Francisco to Santiago

  • San Jose Mineta International Airport (SJC) is an alternative for anyone looking for a different departure airport to San Francisco International Airport (SFO). The airport is about 40 miles away from the Bay area and is less busy compared to SFO meaning shorter queues.
  • If you’re looking for a sustainable airline to fly from San Francisco to Santiago (SCL), Delta Air Lines is a great option. They recently invested close to $1 billion over the next decade towards projects that reduce carbon emissions and advance clean air technologies.
  • When booking an economy class ticket with Delta, the main cabin option comes with more privileges. You get the option of advanced seat selection and you are eligible for an upgrade to first class by adding a small charge instead of paying the full amount for First class tickets.
  • LATAM Airlines offers a lot more amenities on its economy cabin compared to any other airline serving the route. They have free Wi-Fi, power outlets, seatback on-demand TV, and a free snack for your flight.
  • The Bay Area Rapid Transit offers a great commuter option to San Francisco International Airport from downtown San Fran. It is especially convenient when Bay Area traffic is a big problem during rush hours.

Top 5 airlines serving from San Francisco to Santiago

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7951 reviews
8.2Boarding
7.9Entertainment
7.9Comfort
8.5Crew
7.3Food
Airline reviews

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

6.0 GoodWalter, May 2025ONT - SLC
Read more Delta reviews

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Delta flight was on time, seats were comfortable, and crew was nice.

Bathrooms dirty sinks clogged. No one seemed to clean them. Plane very old

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

It was terrible, if they ran flights on time it would make a big difference.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

I actually received a notification from kayak on email but not one by text from Delta when my departure gait changed and I almost missed my flight

New boarding doesn't make sense. Filling front first is slow.

Delta flight was great from the check in all the way to arrival. However, I had a very bad experience. I requested a wheelchair and the wheelchair employee that went to pick me up from the plane in Boston to bring me to the baggage claims told me I have to pay him. I was under the impression that it was a free service and I usually give tips but the person forced me to pay and since I said no because I was upset with his demand when my daughter walked in to pick me up he demanded payment from my daughter who paid him thinking maybe now it is a charged service.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

No entertainment but not expected. Unless you are referring to monitor that you can use. Then Al, was fine on all flights.

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

Basic experience, we were delayed causing less time to enjoy our destination and on the way back, we boarded when the flight should have been taking off.

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

It was good, plane is a bit older so seats are somewhat flat

Great from check in all the way to the end. Very happy with Copa

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

Friendly flight team and seamless travel from one stop to next.

I loved my experience. Very safe, Very informative and very friendly.

At JFK the Security line was extremely long and few checkpoints open.

Flight attendant -José? - was over the top friendly and professional. Beautiful new plane with lie flat seats in Business (worth it!)

Boarding seemed to be organized bedlam. For what ever reason, preboarding took longer than 20 minutes. Made the plane 20 minutes late taking off. Luckily we arrived on time. Flight crew seemed very friendly. Only slight turbulence.

They hired a new catering company the same day of my flight. They botched the job by not delivering the right carts and after THREE HOURS waiting, the flight crew timed out (flight was 19 hours long and FAA rules state crew can’t work more than 14 hours long). So they CANCELED OUR FLIGHT!! Worst experience ever. Avoid UAL at all costs.

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

get E+, a must for 5 hours flight if you are tall

Liked fold flat bed. Didn’t like having no window. Didn’t like poor choice of food and being served dinner very late, hours after take off of a 7:40pm flight. Servers not friendly. Food horrible in business class.

Everything is good except the dinner and breakfast. The sandwich is very delicious. Toilet is clean, I only use one of them. Flight attendants are very nice. 👍👍

Compared with other carriers business class for an overnight was not worth the extra expense.

Easy to board. Flight was super crowded though so I didn't sleep well on that cross country red-eye flight. The aisles seem ot have gotten narrower and the seat smaller whn luggage and people are getting bigger so it would be AWESOME to have more space and breathing room in general ;)

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Eventless. It was a good flight and good crew. Can’t complaint.

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

British Airways staff are very polite and willing to help.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

Worst seats I’ve ever had !!! The seats were very narrow and uncomfortable and misaligned with the seats in front of mine leading to bottom of the seat in front of mine pressing on my legs for 15.5 hours !

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

Amazingly comfy flight - I had upgraded for a reasonable price and it was worth it. The food also was good.

Everything you need to know for your flight from San Francisco to Santiago

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