$173 Find Cheap Flights from San Francisco to Florida Keys - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Florida Keys departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from San Francisco to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$270
Key West
Key West1 stop$301
Miami
Miami1 stop$270
Key West
Key West1 stop$301

Book Cheap San Francisco to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Florida Keys

Tue, Sep 15 - Tue, Sep 22
Frontier Logo
9:00 am - 12:46 am
SFO
-
MIA
12h 46m
2 stops
Frontier Logo
2:37 pm - 10:28 pm
MIA
-
SFO
10h 51m
1 stop
$270Frontier
Mon, Oct 19 - Mon, Oct 26
Frontier Logo
10:48 pm - 12:14 pm
SFO
-
MIA
10h 26m
1 stop
Frontier Logo
6:45 am - 10:29 am
MIA
-
SFO
30h 44m
2 stops
$270Frontier
Fri, Sep 25 - Mon, Sep 28
Multiple Airlines Logo
11:42 am - 12:46 am
SFO
-
MIA
10h 04m
1 stop
Multiple Airlines Logo
6:16 pm - 9:37 am
MIA
-
SFO
18h 21m
1 stop
$275Multiple Airlines
Sat, Sep 19 - Tue, Sep 22
American Airlines Logo
9:54 pm - 6:34 am
SFO
-
MIA
5h 40mnonstop
American Airlines Logo
8:52 pm - 11:59 pm
MIA
-
SFO
6h 07mnonstop
$279American Airlines
Sat, Sep 26 - Mon, Oct 5
American Airlines Logo
8:35 am - 5:17 pm
SFO
-
MIA
5h 42mnonstop
American Airlines Logo
8:47 pm - 11:59 pm
MIA
-
SFO
6h 12mnonstop
$279American Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
11:00 pm - 7:47 am
SFO
-
MIA
5h 47mnonstop
United Airlines Logo
7:29 am - 10:59 am
MIA
-
SFO
6h 30mnonstop
$279United Airlines
Sat, Sep 12 - Wed, Sep 16
United Airlines Logo
8:45 am - 5:35 pm
SFO
-
MIA
5h 50mnonstop
United Airlines Logo
4:58 pm - 8:10 pm
MIA
-
SFO
6h 12mnonstop
$279United Airlines
Wed, Sep 9 - Mon, Nov 2
Multiple Airlines Logo
11:42 am - 12:46 am
SFO
-
MIA
10h 04m
1 stop
Multiple Airlines Logo
6:07 pm - 9:36 am
MIA
-
SFO
18h 29m
1 stop
$285Multiple Airlines
Tue, Nov 17 - Tue, Nov 24
Delta Logo
11:51 am - 12:57 am
SFO
-
MIA
10h 06m
1 stop
Delta Logo
5:00 pm - 11:51 pm
MIA
-
SFO
9h 51m
1 stop
$299Delta
Wed, Nov 18 - Mon, Nov 23
Delta Logo
6:00 am - 6:40 pm
SFO
-
MIA
9h 40m
1 stop
Delta Logo
3:37 pm - 1:22 am
MIA
-
SFO
12h 45m
1 stop
$299Delta
Booking Insights

KAYAK's insights & trends for San Francisco to Florida Keys flights

Get data-powered insights and trends into flights from San Francisco to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest time of day to fly to Florida Keys?

The average price for all round-trip flights from San Francisco to Florida Keys depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Florida Keys is generally in the morning, when round-trip flights cost $507 on average. The most expensive time of day to fly to Florida Keys is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $614.

Can I save money by flying with a layover from San Francisco to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $653, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from San Francisco to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Florida Keys is September, when tickets cost $347 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $491 and $474 respectively.

What’s the cheapest day of the week to fly from San Francisco to Florida Keys?

The average price of all round-trip flights from San Francisco to Florida Keys clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from San Francisco to Florida Keys, look for departures on Wednesdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Florida Keys, Friday is the cheapest day to fly and Monday is the most expensive.

How far in advance should I book a flight from San Francisco to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Florida Keys, you should book around 3 weeks before departure, which saves you about 24% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low season

September

Cheapest flight

$173
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 33% increase in price.
Flight from San Francisco to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from San Francisco to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Francisco to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8497 reviews
7.8Entertainment
8.1Boarding
7.8Comfort
7.2Food
8.5Crew
Airline reviews

Crew was absolutely fantastic and we’re so welcoming and friendly ❤️

10.0 ExcellentRachel, Jul 2026
SFO - SLC
Read more Delta reviews

Crew was absolutely fantastic and we’re so welcoming and friendly ❤️

Flight delayed four separate times. I’m now one hour hours late to landing.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

New boarding doesn't make sense. Filling front first is slow.

It was a short, comfortable flight. It did leave an hour late due to the pilot having to be replaced (family emergency) but that didn’t inconvenience myself & my friend. The situation was explained, eventually.

Lost one piece of luggage even though I checked in 2.5 hours before the flight

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

No screens or meal options. Freezing cold. Dirty seats. Left late.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

Not good. Flight crew, was not friendly and just shoved stuff at us. Not the way I like to travel.

Aside from the little delay, overall was flight good. Made it safely. Thanks!

Over the course of 7 months of travel, I can count on my hand the number of times the flight has departed on time. Majority of the instances have been related to non-weather reasons. Would not recommend flying this Airline

The plane was spartan, the seats not that comfortable. It was like flying a super low budget airline. They charged for coffee!!! I have never, ever experienced that before.

I had no problems but the changing of planes that I was supposed to be on was confusing. Maybe it would be helpful to let people know your flight changed. Not everyone understands airports or how flying works.

Flight was delayed multiple times without giving any particular reason and the only thing that was communicated was that 'Aircraft is getting ready'. I was stuck at SFO airport for 15 hours and finally took Southwest Airlines flight back home to Dallas.

I was not clear if food was offered or not.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

It was the worst experience ever. Cabin temperature cold, for which they did not have any blankets upon my asking. We paid $125 extra for each passenger to get extra space sits; the sits were ridiculously small, tight, and uncomfortable! The flight attendant dropped ice on me and my sister! All in all, American Airlines deserves below zero!

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

Seats were great, the staff was great, and the food was about the best I've had on a plane, and is especially the best of any US-based carrier I've flown. Free Wi-Fi was also great.

It was inexplicably canceled and we are stuck in LA, haven't gotten home and it has been an inconvenience having lost work (on unpaid leave for my husband).

Rude crew member. She seemed annoyed at me without me saying a single word. Also loudly admonished me for having my bag next to my seat instead of tucked away before landing. Just telling me to put it away and guiding me without giving me a lecture would have been enough.

Too many long delays with JetBlue. Worst major airline that serves JFK but unfortunately I keep going back because of the prices.

Little snafu at boarding. Staff communicated with gate poorly. Flight attendant was rude making disembark early. This was an older mint class. Needs an overhaul for sure. Food was good. The male flight attendant was really nice.

They put me on a chair in between two men, one overweight who was almost falling on top of me, and the other was even uncomfortable because I was half falling because of what the other was pushing me. I stayed with. my feet were swollen from fluid retention and from being unable to accommodate myself. it was very uncomfortable. I asked for help but they told me that the flight was full and they couldn't help me. I got off the plane almost unable to walk due to the inflammation. and then at FLL airport I asked for help because I couldn't go to my next flight, which was a connection.

I really liked the way snacks and drinks were available throughout the flight!!! The flight attendants were also all fantastic!

Always like Jet Blue! It seems, however, that people are getting bigger & seats are getting smaller! We had a very full flight and I couldn't get an aisle seat like I always do. I wish there were more leg room. People sitting next to me were very nice though so it was fine to disturb them if I needed to use the restroom. Otherwise the flight was fine but a bit long.

None of the in flight Direct TV worked. A better selection of Shows would have been better. The baggage was s low. Otherwise we enjoyed our flight!

the staff was very helpful and the airline was very good.

I really didn't like anything. Paid for my checked luggage online ($79) and then was told that I would have to paid another $79 for my carry on. Was not allowed to enter the terminal until 3 hours before my flight and when I finally was allowed to check my bag and enter, my flight was delayed 3 times. When I finally landed, we were all instructed to "run off the plane" as they had to do a quick turn around to Las Vegas. Me and several of my flying companions will never fly Frontier again.

They didn’t offer a water, even after I asked

Frontier had yet another flight cancellation. Have never made a complete round trip with this airline without at least one leg getting cancelled. Miserable flights - dirty, uncomfortable planes that apparently always have issues since I've had multiple delays and cancellations with them.

No frills for sure. No gate announcements about flight delay, not even water to drink on the flight.

I loked walking out on the tarmac to board and no first class. I didn't like that they have no snacks or onboard wifi to bide your time.

It was a redeye flight, so every passenger just wanted to sleep, but through the entire flight, the flight crew made announcements over the loudspeaker at maximum volume every few minutes making sleep impossible. For example: it’s 2am, and the crew decides to give an extremely detailed announcement about snacks and beverages for sale. And 3am is the perfect time to wake up everyone with a lengthy announcement about how to get a coffee refill and how to take advantage of new offer from frontier for a credit card.

While booking it was not obvious that I had to pay for carryon. Realized it only during check-in. Overall, meh!

Stop changing gates at sfo. When you are elderly going back for it’s not fun.

After 5 hours of delay, they cancelled the flight. Very disappointed

My flight to LA was cancelled. I waited at the airport for 3 hrs saying it was delayed and then all of a sudden it was cancelled. Frontier only gave me a voucher and refund but could not rebook me. Flights on other airlines were too expensive last minute. I had to drive down to LA and didn’t even take my return flight home since I had to drive. One of the worst airline experiences in my life. It’s crazy how airlines can just upend people’s plans just like that.

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports