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Find cheap flights from Florida Keys to San Francisco from $75

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
sam. 5/25
sam. 6/1

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Good to know

Low season

January

High season

July

Cheapest flight

$75
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Miami to San Francisco

FAQs for booking flights from Florida Keys to San Francisco

  • How does KAYAK find such low prices on flights from Florida Keys to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Florida Keys to San Francisco?

Find which airlines fly direct from Florida Keys to San Francisco, which days they fly and book direct flights.

Nonstop departures

Florida Keys to San Francisco

Monday

AIR PREMIA, ANA, Aer Lingus, +79 more

AIR PREMIA, ANA, +80 more

Tuesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Wednesday

AIR PREMIA, ANA, Aer Lingus, +80 more

AIR PREMIA, ANA, +81 more

Thursday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Friday

AIR PREMIA, ANA, Aer Lingus, +79 more

AIR PREMIA, ANA, +80 more

Saturday

ANA, Aer Lingus, Aeromexico, +81 more

ANA, Aer Lingus, +82 more

Sunday

AIR PREMIA, ANA, Aer Lingus, +81 more

AIR PREMIA, ANA, +82 more

See more direct flights

Nonstop returns

San Francisco to Florida Keys

Monday

AIR PREMIA, ANA, Aer Lingus, +79 more

AIR PREMIA, ANA, +80 more

Tuesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Wednesday

AIR PREMIA, ANA, Aer Lingus, +80 more

AIR PREMIA, ANA, +81 more

Thursday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Friday

AIR PREMIA, ANA, Aer Lingus, +79 more

AIR PREMIA, ANA, +80 more

Saturday

ANA, Aer Lingus, Aeromexico, +81 more

ANA, Aer Lingus, +82 more

Sunday

AIR PREMIA, ANA, Aer Lingus, +81 more

AIR PREMIA, ANA, +82 more

See more direct flights
See more direct flights

Top 5 airlines serving from Florida Keys to San Francisco

 
Need help choosing which airline to fly with from Florida Keys to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 11004 reviews
8.6crew
8.2boarding
8.0entertainment
7.9comfort
7.5food
Airline reviews

There was a loud squeaky sound the whole time we were flying.

6.0 GoodEliza, Apr 2024SAN - LAX
Read more about Delta reviews

There was a loud squeaky sound the whole time we were flying.

Had a broken tray in business class. Crew just shrugged it off.

I didn’t like that I could not select my seat and was assigned a seat when I checked in at LAX

Great experience overall. Check in at Austin was congested as they only have about 6 check in kiosks, one was broken, and there was a lot of Spring Break travelers.

Bag drop off was slow and annoying. Only 2 agents at the entire delta desk, and no one directing traffic for what line to be in, many confused people slowed down the process. Boarding was fine. Seats in Delta comfort plus were fine. Snacks were great! Definitely a bonus. The entertainment system was awful — old, slow, not responsive, and completely unable to play games due to some kind of error. But on the other hand, thank you to Delta for the free WiFi. That made it better.

Everything was very good other than I had selected a specific seat when I booked the flight and they changed it once I checked-in the day before my flight. I was still in first class but lost my aisle seat for a window seat. Being tall, the aisle offers more comfort so I always select an aisle seat.

Flight diverted in SD. Later take off in Seattle by 1.3hrs

Crew was not friendly when I went to request a seat change.

Really impressive staff at airport and on plane, especially given how busy it was

Was a great smooth flight from Detroit to San Diego.

Business class is great. New airplane, very comfortable, better than some of the major airlines I am used to

great flight. Pilot was communicative, flight attendants were excellent. Really nice experience except my tv didn’t work.

Overall, the flight was better than the flight I took to go to Florida, which had a bunch of problems. The crew is really nice and the plane was new so it had a small problem when we were on the runway, but the flight itself was great. They even made some time back up, which is always a good thing.

Everything was good except for deplaning in NY. Took way too long!!

Jet Blue keeps getting iit wrong. 4 hour mechanical delay followed by terrible boarding experience. This is my third horrific jet blue flight in 2024. I am going to try to avoid this loser in the sky

Delayed by almost an hour - I also noticed that all JetBlue flights departing from PBI were delayed yet the weather was perfect.

My experience with JetBlue was fantastic! The service was top-notch, the flight was smooth, and the staff were friendly and helpful. I would definitely fly with them again.

Service for food to our seat was a bit slow. Snack choices were just pretzels or baked chips. My seat cushion was not attached. Other than Barbie, video choice were not very good or current.

It took an hour to get my bag after landing. Not exaggerating

I had a horrible experience with TSA at the airport. I had to go through TSA several times as there was some issue each time with a piece if clothing I had on. It was so busy & chaotic that I ended up forgetting my Apple laptop at TSA. It’s been days & I can’t get through to anyone to get useful info on how to get it back. I’m very angry because contacting lost & found shouldn’t be this difficult. Employees should know what is going on at their place of work. It seems no one knows as everyone’s answers are contradictory, or you can’t speak directly to anyone as the calls are automated. Very upsetting.

delay several times and wait extra long to board. no entertainment service because there are problem for some rows. always encounter some delays for the last flight of the day.

This was a Lufthansa flight. Disappointing main meal. Very rough over Canada and arrival at FRA. IFE was almost unusable.

I was not able to buy food in the flight. They refer to include your Credit card in the APP, and if you are not from USA (i have a credit card form Canada) it is not possible

United airline kept delaying our flight back to Phoenix for 8 hours before they cancelled it! If they know that we are not flying out for whatever the reason is, why did they keep lying to us for hours. We could find another flight earlier or even find a hotel with a shuttle. But cancellation at about midnight was not fun. We stayed in the airport all night till the following morning when we bought an Alaska tickets to go back to Phoenix. Total of 14 hours in the airport.

Poor seating comfort, seat cushion too thin, very uncomfortable. My luggage didi not make the flight due to equipment change. At least. United had it delivered the next day. I was without my toilet items for one day.

My experience is based on one crew member. I had found my seat and sat down but there was a gentleman to claimed to the flight attendant I was in his seat. She then came to me and curtly said, "I need your ticket!" No hi, no excuse me may I see your boarding pass? NOTHING! I was taken aback by her attitude and she repeated herself, "your ticket?!?!" I calmly responded with ok, here you go. Only to discover the gentleman was looking at the wrong boarding pass. She gave me back my ticket with no apology. She then was curt with another man who was putting his coat in the overhead bin, already helped by another flight attendant who said it was fine. She realizes it's ok and then asks him if he drinks. The look on the man's face was priceless. She said she was going to comp him drinks. He gets offered a comp drink for a coat as well as an apology, and I got no apology.

Flight cancelled because of the grounded 737s. United was good about it and got us onto a later Alaska Airlines flight to Oakland (not San Francisco as originally intended). Had to go through security again and my wife dropped her MacBook Pro, which broke, a $2,500 whoopsie. But we made it home.

Delays, excuses, delays, and more delays. This company is BROKEN.

Horrible. Delayed on both planes several times. No attempt to fix it

I contacted both carriers months beforehand to change the cabin (booked in April) but to no avail (united asked to contact Swiss since it was their equipment, Swiss told me to reach out to united). So yeah… My seat was pretty worn down, legroom on 27K was more than enough, but still economy seating so, getting to know your neighbours was easy. According to ground staff, the flight was massively overbooked- and this showed. I ordered a gluten free meal beforehand (which was honoured) but for breakfast got a bread roll and croissant 🤷🏼‍♂️ The connection itself is great. Leaving SFO late PM to arrive at ZRH in the afternoon makes it easier to get re adjusted again. However, and since I’ve flown this connection a couple of times in the past, I will rather deal with one carrier only and include a layover on the east coast.

Somehow I got “offloaded” even though I had my boarding pass and was in transit Food is horrible Staff were nice and cheerful No headphones were provided on 11 hours flight

Fight crew was not very attentive and the bastions were gross!

Our flight was great we left Kona earlier and got into LAX almost an 1hour earlier as well. LAX AA is in repair so to get out and found our bus to get pick up was a bit confusing.

Plane was good but was delayed. probably not AA fault but caused a 1 hour delay. Seating was cramped.

The staff were very helpful with lots of refreshments on offer. The toilets were clean. The seats were comfortable and entertainment was good. No complaints, it was excellent.

5 hour flight - full flight - not enough room to use my computer - slightly delayed - Admirals club was excellent quality food, drink made up for flight seating. No food offerred on flight, you ahd to prebook.

We experience delays on departure and connecting flights resulting in 14 hour to our next departure. We were accommodated with a night's stay but was only provided a 12 dollar meals accommodation. The airlines rules state.at least 50 dollars. In any case, it can not make up for the whole day missed on our vacation in Sydney Australia.

I can say I will not be taking this airline again any time soon. Seat were uncomfortable and too tight. Lack of chair screen and little overhead space.

Plane felt so crowded and tightly packed. The chair itself was not comfortable.

They attended to my needs as I couldn't walk and they provided a wheelchair for me.q

They cancelled the flight then did nothing to help us rebook. It was awful - I won’t fly with them again

The truck that was refueling the plane drove away with the hose still connected to the plane and ripped part of the plane off with it

Crew members are very rude and not cooperate with passengers.

30 minute delay due to boarding and settling of a family.

The boarding time. I was in Section 1 the lady in charge just let people in section 3 without see us. Make a line , I have to step out and ask her. We were in the line and she just take my ticket and that’s it, so if I don’t ask her she could leave us at the end! We paid more for that privilege and. She doesn’t care….

See my previous comment which is mostly about our flight from Phoenix to SFO

I am HIGHLY unhappy with the amount of money I spent on the flight. Paid in advance only to find the flight at a discount price a week or so before the flight. I will not fly frontier again and have bad mouthed your business since to anyone I have spoken with about flying (which has been many a people). Crew was mediocre and instead of moving me to a spot where I could gain some leg room they sat their flight attendant there. Won’t be flying frontier in the future.

Well, I didn’t have food! So NA wasn’t an option. I’ll be back!

First time flying with Frontier . From buying tickets ,getting boarding pass and boarding plane was super easy. Definitely would fly again with Frontier .

The check in at the airport was awful. Told I need to pay for a bag. The item was taken at screening. I went back to get my $ back and they gave me a coupon with a QR code that doesn’t work. Worst costumer service ever!!!!!

Book cheap flights from Florida Keys to San Francisco

Recent round-trip flight deals

5/8mer.
1 stopFrontier
10h 53mMIA-SFO
5/15mer.
1 stopFrontier
30h 32mSFO-MIA
$149
5/8mer.
1 stopFrontier
10h 53mMIA-SFO
5/14mar.
1 stopFrontier
27h 49mSFO-MIA
$161
9/14sam.
nonstopAmerican Airlines
6h 15mMIA-SFO
9/24mar.
nonstopAmerican Airlines
5h 42mSFO-MIA
$179
5/10ven.
3 stops
22h 31mMIA-SFO
5/14mar.
1 stop
27h 49mSFO-MIA
$201
5/10ven.
3 stops
22h 31mMIA-SFO
5/14mar.
2 stops
25h 33mSFO-MIA
$216
9/14sam.
nonstopUnited Airlines
6h 12mMIA-SFO
9/24mar.
1 stopUnited Airlines
7h 50mSFO-MIA
$218
5/17ven.
nonstopUnited Airlines
6h 27mMIA-SFO
5/19dim.
nonstopUnited Airlines
5h 45mSFO-MIA
$225
9/17mar.
1 stopAmerican Airlines
8h 25mEYW-SFO
9/21sam.
1 stopAmerican Airlines
8h 36mSFO-EYW
$248
5/4sam.
1 stopDelta
9h 57mMIA-SFO
5/6lun.
1 stopDelta
10h 08mSFO-MIA
$256
5/17ven.
1 stopDelta
9h 07mMIA-SFO
5/19dim.
1 stopDelta
10h 08mSFO-MIA
$271

Search by stops

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Recent one-way flight deals

5/8mer.
1 stopFrontier
10h 53mMIA-SFO
$75
5/18sam.
1 stopFrontier
27h 30mMIA-SFO
$85
10/1mar.
nonstopAmerican Airlines
6h 15mMIA-SFO
$92
5/17ven.
nonstopUnited Airlines
6h 27mMIA-SFO
$110
9/4mer.
1 stopDelta
8h 09mEYW-SFO
$128
6/28ven.
1 stopDelta
8h 50mMIA-SFO
$128
5/22mer.
1 stopJetBlue
9h 14mMIA-SFO
$129
5/3ven.
nonstopAmerican Airlines
6h 34mMIA-SFO
$134
8/24sam.
nonstopUnited Airlines
6h 12mMIA-SFO
$140
6/3lun.
1 stopJetBlue
8h 56mMIA-SFO
$153

Search by stops

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Last minute flights from Florida Keys to San Francisco

Last minute flight, train and bus deals

4/29lun.
multi-stopFrontier
26h 13mMIA-SFO
5/11sam.
multi-stopFrontier
28h 32mSFO-MIA
$224
4/29lun.
multi-stopFrontier
22h 46mMIA-SFO
5/4sam.
multi-stopFrontier
29h 54mSFO-MIA
$255
4/27sam.
multi-stopDelta
12h 04mMIA-SFO
5/4sam.
multi-stopDelta
11h 02mSFO-MIA
$323
4/28dim.
multi-stopAmerican Airlines
9h 21mMIA-SFO
5/10ven.
multi-stopAmerican Airlines
7h 27mSFO-MIA
$366
4/26ven.
nonstopAmerican Airlines
6h 34mMIA-SFO
4/30mar.
nonstopAmerican Airlines
5h 30mSFO-MIA
$380
4/25jeu.
multi-stopDelta
9h 41mMIA-SFO
4/27sam.
multi-stopDelta
10h 10mSFO-MIA
$432
4/26ven.
nonstopUnited Airlines
6h 27mMIA-SFO
4/29lun.
multi-stopUnited Airlines
8h 14mSFO-MIA
$449
4/27sam.
nonstopUnited Airlines
6h 27mMIA-SFO
5/4sam.
multi-stopUnited Airlines
12h 16mSFO-MIA
$451
4/26ven.
multi-stopAlaska Airlines
10h 01mMIA-SFO
4/29lun.
multi-stopAlaska Airlines
19h 01mSFO-MIA
$798
4/26ven.
multi-stopAlaska Airlines
28h 02mMIA-SFO
4/29lun.
multi-stopAlaska Airlines
17h 26mSFO-MIA
$1,024

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Flights to San Francisco

Destination:

San Francisco (SFO)United States

Return flight deals:

San Francisco - Florida Keys

Cabin classes:

$218
$174
$169
$38