Which airports can I use when flying from Santa Ana to Guayaquil?

Flights from Santa Ana to Guayaquil usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

Do I need a passport to fly from Santa Ana to Guayaquil?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Santa Ana to Guayaquil changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $974 to $3,261. That means the highest observed fare was about 3x higher than the lowest one.

What is the time difference between Santa Ana and Guayaquil?

Guayaquil is 2 hours ahead of Santa Ana (Ecuador Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?

Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include: • Europcar • Fox • Sixt • Alamo • keddy by Europcar

Which airline is the cheapest to fly from Santa Ana to Guayaquil?

United Airlines ($974) offered the cheapest round-trip ticket from Santa Ana to Guayaquil in the last 5 days.

$402 CHEAP FLIGHTS from John Wayne (Santa Ana) to Guayaquil (SNA - GYE)

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Flight Deals

Cheap Flights from Santa Ana to Guayaquil (SNA-GYE)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from Santa Ana to Guayaquil

Sun, Nov 22 - Mon, Nov 30

2:59 pm - 11:40 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

29h 41m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

2:47 pm - 9:45 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

33h 58m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$974United Airlines

Tue, Nov 24 - Mon, Nov 30

8:05 am - 5:35 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

30h 30m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

2:47 pm - 9:45 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

33h 58m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,009United Airlines

Sun, Nov 22 - Mon, Nov 30

2:59 pm - 11:40 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

29h 41m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

2:47 pm - 8:46 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

32h 59m3 stops Panama City Tocumen Intl Houston George Bush Intcntl San Francisco

$1,036United Airlines

Sun, Nov 22 - Sun, Nov 29

2:59 pm - 11:40 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

29h 41m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

2:47 pm - 9:50 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

34h 03m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,042United Airlines

Tue, Nov 24 - Mon, Nov 30

8:05 am - 8:56 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

33h 51m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

12:25 pm - 8:46 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

35h 21m3 stops Panama City Tocumen Intl Houston George Bush Intcntl San Francisco

$1,071United Airlines

Mon, Nov 23 - Sun, Nov 29

8:05 am - 8:56 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

33h 51m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

2:47 pm - 9:50 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

34h 03m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,077United Airlines

Mon, Nov 23 - Fri, Nov 27

8:05 am - 11:40 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

12h 35m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

12:25 pm - 1:51 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

28h 26m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,096United Airlines

Sun, Nov 22 - Fri, Nov 27

2:59 pm - 8:56 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

26h 57m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

8:25 am - 1:51 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

32h 26m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,112United Airlines

Mon, Nov 23 - Thu, Nov 26

8:05 am - 8:56 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

33h 51m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

12:25 pm - 9:50 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

36h 25m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,162United Airlines

Sun, Nov 22 - Thu, Nov 26

2:59 pm - 8:56 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

26h 57m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

2:47 pm - 12:07 pmGYE Guayaquil Jose Joaquin de Olmedo-SNA Santa Ana J. Wayne/Orange Cnty

24h 20m2 stops Panama City Tocumen Intl San Francisco

$1,179United Airlines

Recent one-way flight deals from Santa Ana to Guayaquil

Thu, Dec 3

12:08 pm - 1:20 amSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

34h 12m3 stops Denver Intl Chicago O'Hare Intl Punta Cana

$402Multiple Airlines

Tue, Dec 29

7:30 am - 1:42 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

51h 12m3 stops Las Vegas Harry Reid Intl Miami Panama City Tocumen Intl

$496Multiple Airlines

Thu, Dec 3

3:20 pm - 6:25 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

24h 05m2 stops Houston George Bush Intcntl Bogotá El Dorado

$518Multiple Airlines

Thu, Dec 24

8:15 am - 11:41 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

12h 26m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

$520United Airlines

Wed, Dec 30

12:11 pm - 8:57 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

29h 46m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

$543United Airlines

Wed, Dec 30

12:29 pm - 8:57 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

29h 28m3 stops Denver Intl Miami Panama City Tocumen Intl

$553Multiple Airlines

Fri, Dec 25

8:15 am - 8:57 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

33h 42m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

$562United Airlines

Sun, Dec 27

3:13 pm - 4:50 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

22h 37m2 stops Houston George Bush Intcntl Quito Mariscal Sucr

$581Multiple Airlines

Sun, Dec 27

12:37 pm - 2:30 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

22h 53m2 stops Phoenix Sky Harbor Intl Miami

$658American Airlines

Mon, Dec 28

6:30 pm - 11:41 pmSNA Santa Ana J. Wayne/Orange Cnty-GYE Guayaquil Jose Joaquin de Olmedo

26h 11m3 stops San Francisco Washington, D.C. Dulles Intl Panama City Tocumen Intl

$719United Airlines

Booking Insights

Price, demand and travel trends for Santa Ana to Guayaquil flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Which airline is the cheapest to fly from Santa Ana to Guayaquil?: United Airlines ($974) offered the cheapest round-trip ticket from Santa Ana to Guayaquil in the last 5 days.

Find deals

Cheapest flight	$402

One-way flight from Santa Ana to Guayaquil

When to book flights from Santa Ana to Guayaquil

Are your dates flexible? Find out the best times to travel from Santa Ana to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Do I need a passport to fly from Santa Ana to Guayaquil?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
Have flight prices from Santa Ana to Guayaquil changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $974 to $3,261. That means the highest observed fare was about 3x higher than the lowest one.
What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?
Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include:

• Europcar
• Fox
• Sixt
• Alamo
• keddy by Europcar
Which airports can I use when flying from Santa Ana to Guayaquil?
Flights from Santa Ana to Guayaquil usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).
What is the time difference between Santa Ana and Guayaquil?
Guayaquil is 2 hours ahead of Santa Ana (Ecuador Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

If you're arriving late at night and need somewhere to stay, check out these hotels close to Guayaquil Jose Joaquin de Olmedo Airport.

• Radisson Hotel Guayaquil
• Wyndham Guayaquil Puerto Santa Ana
• Sheraton Guayaquil Hotel

More options for your flight from Santa Ana to Guayaquil

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SNA - GYE

$402 Find Cheap Flights from John Wayne (Santa Ana) to Guayaquil - Compare and Save

Everything you should know

Cheap Flights from Santa Ana to Guayaquil (SNA-GYE)

Recent round-trip flight deals from Santa Ana to Guayaquil

Recent one-way flight deals from Santa Ana to Guayaquil

Price, demand and travel trends for Santa Ana to Guayaquil flights

Which airline is the cheapest to fly from Santa Ana to Guayaquil?

Key details for Santa Ana to Guayaquil flights

Cheapest flight

When to book flights from Santa Ana to Guayaquil

Your Santa Ana to Guayaquil flight questions, answered

Your guide to booking Santa Ana to Guayaquil flights

More options for your flight from Santa Ana to Guayaquil

Complete your trip to Guayaquil with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from John Wayne (Santa Ana) to Guayaquil

Find direct flights to and from Santa Ana and Guayaquil

Flights from domestic origins to Guayaquil

Flights to other popular destinations