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Find cheap flights from John Wayne (Santa Ana) to South America from $186

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to South America departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Jumaat 6/7
Jumaat 6/14

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$619
Bogotá
Bogotá2 stops$352
Cartagena
Cartagena2 stops$461
Santiago
Santiago2 stops$829
Quito
Quito1 stop$532
Guayaquil
Guayaquil2 stops$599
Cali
Cali2 stops$564
Cusco
Cusco2 stops$895
Barranquilla
Barranquilla2 stops$569

Good to know

Low season

November

High season

February

Cheapest flight

$186
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Santa Ana to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to John Wayne (Santa Ana) with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 9% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 4 airlines serving from Santa Ana to South America

 
Need help choosing which airline to fly with from Santa Ana to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10793 reviews
7.4Food
8.6Crew
7.9Comfort
8.2Boarding
8.0Entertainment
Airline reviews

There was a loud squeaky sound the whole time we were flying.

6.0 GoodEliza, Apr 2024SAN - LAX
Read more about Delta reviews

There was a loud squeaky sound the whole time we were flying.

I didn’t not like that I could not select my seat and ended up with the worse seat.

The landing was bad and the hostess came two times and i was sleeping but when she served the person that nexts to me I woke up and she didn’t even asked me if I need any drink or snacks two times!!!!

Plane was late because of a mechanical malfunction and the food listed as available was not. Flight attendants seem over worked and under paid. They just done seem happy. And that can be seen in their faces.

Waited 3 hours on a plane to de-ice due to manpower issues. Waited another hour and a half once we landed because of a gate issue. Missed my connections. Created. A total of 13 hours of delay.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

Plane was turned around due to fog half way into the flight, Delta did not properly direct passengers to stay on same flight and instead failed to properly rebook on Alaska

Honestly, I didn’t expect that I will experience this long time wait during the check in. There was only one person who was taking care of the passengers for the economy class and it took us to wait about one hour to do our check i. As a result we barely get to the airplane as the gate was at the end of the airport. That is totally not professional where one crue is working at the registration desk with economy and 3-4 crues are helping for the business class.

Like most domestic flights in the US, you are basically on your own with this airline when it comes to food, so be sure to purchase meals and drinks ahead of time or expect to arrive starving and dehydrated (like I was).

You need to be a hacker to get the (Free) WiFi

TAM is a real disappointment. We had to jump on a crowded bus for a 6am flight - although there were at least 15 available fingers that could have been used by our plane. Then, we were placed on row 30 - the last row of the plane, despite having purchased the tickets a long time ago and being TAM gold plus members. Note: worse seats on the plane. Great way of rewarding your frequent flyers TAM ! I now remember why I stoped flying internationally with TAM and moved to American, United, Swiss, Lufthansa and BA. TAM has no respect for its customers.

Everything was as you would expect in coach - fine. Flight was close to on time.

It was confusing because I got a notification that my gate was changed when in reality it wasn’t

I missed my plane because there was a lot of people during the migration process. The airline has the chance to care for their clients and they could get the passengers missing in the flight. I lost a day of work and Montfort transportation to go back home and go to the airport again. Unfortunately the airline doesn’t care about that. I use latam at least 4 times a year, so I guess I need to be treat better. In addition, one on my baggages didyarricw to my destination. So frustrated with this trip.

It’s been some time since I saw the plane and the cabin that old and worn out.

No air in the middle rows. Had a hard time breathing. Was dying of heat.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

It was a good experience, the flight was a little too long & the food was ok

Hostile flight attendants. Second flight with Jose so much better. Arrived 1/2 hour early. Thanks.

I paid $380 for my one-way ticket from California to Minnesota. The fair did not include online check-in. I received instructions from their app to check in at a kiosk. At the kiosk, the boarding pass would not print until an actual person came to verify that I had a personal item and not a carry-on item, On the plane, the person next to me was drunk and allowed to continue to order alcohol. United is garbage I’d rather fly spirit.

Do not like the feeling of being in the basic economy. Everyone should feel good no matter what.

Terrible! The plane was old and you are required to connect your own device to their Wi-Fi rather than have entertainment options in the back of the seat in front of you. The Wi-Fi went out during the flight and there was only one plug for the devices every two seats. Three out of five surrounding my family did not work. The seats and spaces under them were so small I could not fit my backpack, which I’ve always brought on flights and fit before no problem. The crew were unpleasant and patronizing.

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

Hated every minute of it. This flight should have only taken 1.5hrs but was delayed over 10hours. Now I am being told I cannot be compensated or refunded my ticket price or extra leg room, which I purchased but did not receive, because the airline is throwing the blame on the 3rd party I purchased tickets through and 3rd party putting the blame on airline. No one wants to help. They received their money and that's all they care about. Im going on 3 days of still trying to get to my final destination, had to cancel car rental, car insurance and hotel. Currently staying in airport until hotels open up. Thank you Lufthansa, Kayak, Underpricer and United for making this trip the worst ever.

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

United WiFi is consistently unusable (it can take 10 mins to load a single web page). If you need Wifi to do work, be prepared to lose half a day of productivity.

Awful. I got stuck next to a person carrying a dog and behind someone with a dog. People need to board these dogs downstairs. The cabin is crowded enough with your pets

Packed in like sardines, very uncomfortable. Sitting the aisle my shoulder was rammed into numerous times by rushing flight attendants. Also flight was very cold.

the head jack on my seat didn't work and the power outlet didn't work for my seat

Horrible - they lied to me about baggage & boarding, even though I specifically spoke to their agents the day before my flight about my issue. When I showed up they did not let me board and stranded me at my airport until I bought a new flight with money I did not have to spend.

Not sure why JAL partnered with American Airlines because their service is no where near similar. Flight attendants were not friendly and didn’t smile. Food was horrible…

The experience was great and much better than the flight going out. of course I was in first class but the service was excellent

Comfort of seats, ease of boarding. Food selection could be better

Food options were limited which is absolutely embarrassing for a Flight of this size The staff did not come around as much and I am not accustomed to such poor service from American Airlines Drinks I believe were limited to soda and water

Crew were attentive and friendly. Flight was smooth and early! I enjoyed the less crowded plane. Thank you!

We are gluten free, there were not any available complimentary gluten free options.

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

The staff was unprofessional and didn’t communicate very well. The boarding process was very disheveled, potentially due to a power outage the previous day but there was no contingency plan to properly get passengers boarded the following day. Once boarded the aircraft stayed on the tarmac for over 45 minutes due to high winds. The communication was sporadic but an announcement was finally made an additional 30 minutes later that the flight was cancelled but we couldn’t get off the plane. Prior to deplaning one of the gate agents came on the plane and made an announcement for everyone to pickup their checked bags and take a card to rebook a new reservation because they didn’t have adequate staff. Flights were missed, passengers went to different airports and there was little to no assistance from AA.

You cancelled my flight by email then made it very difficult to get in contact with you. Then put me in a flight with a long layover in Mexico returning to the wrong airport in uk. Mind blowing my stressful. I missed see my grand dad because of you.

Book cheap flights from John Wayne (Santa Ana) to South America

Recent round-trip flight deals

5/28Selasa
2 stopsSpirit Airlines
27h 15mSNA-BOG
6/4Selasa
2 stopsSpirit Airlines
21h 19mBOG-SNA
$352
5/28Selasa
2 stopsSpirit Airlines
27h 15mSNA-BOG
6/12Rabu
2 stopsSpirit Airlines
21h 58mBOG-SNA
$356
10/5Sabtu
1 stopUnited Airlines
19h 59mSNA-BOG
10/9Rabu
1 stopUnited Airlines
16h 25mBOG-SNA
$429
10/5Sabtu
1 stopUnited Airlines
16h 29mSNA-BOG
10/8Selasa
2 stopsUnited Airlines
19h 12mBOG-SNA
$434
9/14Sabtu
2 stopsDelta
34h 13mSNA-CTG
9/18Rabu
2 stopsDelta
30h 42mCTG-SNA
$461
9/14Sabtu
2 stopsDelta
34h 13mSNA-CTG
9/17Selasa
2 stopsDelta
35h 36mCTG-SNA
$470
6/5Rabu
2 stopsAmerican Airlines
14h 55mSNA-MDE
6/10Isnin
1 stopAmerican Airlines
18h 56mMDE-SNA
$496
10/23Rabu
1 stopLATAM Airlines
23h 30mSNA-BOG
10/30Rabu
1 stopLATAM Airlines
15h 12mBOG-SNA
$508
6/5Rabu
2 stopsAmerican Airlines
14h 55mSNA-MDE
6/9Ahad
1 stopAmerican Airlines
24h 16mMDE-SNA
$509
10/21Isnin
1 stopLATAM Airlines
21h 50mSNA-UIO
11/8Jumaat
1 stopLATAM Airlines
25h 13mUIO-SNA
$532

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Recent one-way flight deals

6/4Selasa
2 stopsSpirit Airlines
28h 11mSNA-MDE
$186
5/28Selasa
2 stopsSpirit Airlines
27h 15mSNA-BOG
$186
5/28Selasa
1 stopDelta
12h 30mSNA-UIO
$293
6/8Sabtu
2 stopsAmerican Airlines
22h 30mSNA-UIO
$298
5/27Isnin
2 stopsAmerican Airlines
23h 00mSNA-UIO
$304
10/28Isnin
1 stopLATAM Airlines
13h 55mSNA-BOG
$330
10/4Jumaat
1 stopLATAM Airlines
21h 50mSNA-UIO
$330
7/2Selasa
1 stopUnited Airlines
30h 39mSNA-UIO
$382
5/22Rabu
1 stopDelta
11h 00mSNA-BOG
$482
6/9Ahad
1 stopUnited Airlines
15h 20mSNA-GRU
$525

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Last minute flights from Santa Ana to South America

Last minute flight, train and bus deals

5/13Isnin
multi-stopUnited Airlines
26h 40mSNA-LIM
5/19Ahad
multi-stopUnited Airlines
34h 35mLIM-SNA
$736
5/12Ahad
multi-stopLATAM Airlines
21h 45mSNA-LIM
5/18Sabtu
multi-stopLATAM Airlines
13h 32mLIM-SNA
$870
5/12Ahad
multi-stopLATAM Airlines
32h 45mSNA-LIM
5/18Sabtu
multi-stopLATAM Airlines
13h 32mLIM-SNA
$882
5/9Khamis
multi-stopCopa Airlines
23h 52mSNA-LIM
5/18Sabtu
multi-stopCopa Airlines
16h 35mLIM-SNA
$944
5/13Isnin
multi-stopUnited Airlines
28h 39mSNA-LIM
5/19Ahad
multi-stopUnited Airlines
15h 08mLIM-SNA
$953
5/13Isnin
multi-stopAmerican Airlines
21h 30mSNA-LIM
5/20Isnin
multi-stopAmerican Airlines
18h 09mLIM-SNA
$1,053
5/13Isnin
multi-stopAmerican Airlines
14h 05mSNA-LIM
5/20Isnin
multi-stopAmerican Airlines
18h 09mLIM-SNA
$1,058
5/13Isnin
multi-stopDelta
13h 33mSNA-CTG
5/28Selasa
multi-stopDelta
16h 42mCTG-SNA
$1,117
5/10Jumaat
multi-stopDelta
13h 33mSNA-CTG
5/24Jumaat
multi-stopDelta
18h 21mCTG-SNA
$1,126
5/13Isnin
multi-stopCopa Airlines
27h 53mSNA-GIG
5/24Jumaat
multi-stopCopa Airlines
38h 38mGIG-SNA
$1,203

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Santa Ana - South America Flights