$143 Find Cheap Flights from Santa Ana to Mexico City Federal District

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Mexico City Federal District departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City Federal District

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Mexico City Federal District, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Mexico City Federal District, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Mexico City Federal District

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Mexico City
Mexico City1 stop$316
Mexico City
Mexico City1 stop$316

Book Cheap Santa Ana to Mexico City Federal District Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Mexico City Federal District that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Mexico City Federal District

Wed, Oct 15 - Tue, Oct 21
Multiple Airlines Logo
6:45 am - 7:50 pmSNA-MEX
12h 05m1 stop
Multiple Airlines Logo
11:00 pm - 7:14 pmMEX-SNA
21h 14m2 stops
$316Multiple Airlines
Find Deal
Wed, Oct 15 - Tue, Oct 21
Multiple Airlines Logo
6:45 am - 7:50 pmSNA-MEX
12h 05m1 stop
Multiple Airlines Logo
11:45 am - 7:14 pmMEX-SNA
8h 29m1 stop
$327Multiple Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Multiple Airlines Logo
8:09 pm - 7:50 pmSNA-MEX
22h 41m1 stop
Multiple Airlines Logo
11:45 am - 7:14 pmMEX-SNA
8h 29m1 stop
$329Multiple Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Multiple Airlines Logo
8:09 pm - 7:50 pmSNA-MEX
22h 41m1 stop
Multiple Airlines Logo
11:00 pm - 7:14 pmMEX-SNA
21h 14m2 stops
$350Multiple Airlines
Find Deal
Fri, Oct 17 - Wed, Oct 22
Multiple Airlines Logo
8:09 pm - 7:50 pmSNA-MEX
22h 41m1 stop
Multiple Airlines Logo
11:45 am - 7:14 pmMEX-SNA
8h 29m1 stop
$373Multiple Airlines
Find Deal
Fri, Oct 10 - Mon, Oct 13
Multiple Airlines Logo
6:45 am - 7:50 pmSNA-MEX
12h 05m1 stop
Multiple Airlines Logo
11:45 am - 10:03 pmMEX-SNA
11h 18m1 stop
$374Multiple Airlines
Find Deal
Tue, Oct 14 - Mon, Oct 20
Multiple Airlines Logo
6:45 am - 9:10 pmSNA-MEX
13h 25m1 stop
Multiple Airlines Logo
11:45 am - 10:03 pmMEX-SNA
11h 18m1 stop
$377Multiple Airlines
Find Deal
Sun, Oct 12 - Tue, Oct 14
Multiple Airlines Logo
8:09 pm - 9:10 pmSNA-MEX
24h 01m1 stop
Multiple Airlines Logo
11:45 am - 7:14 pmMEX-SNA
8h 29m1 stop
$381Multiple Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Frontier Logo
12:01 pm - 10:45 amSNA-MEX
20h 44m2 stops
Frontier Logo
8:10 am - 6:48 pmMEX-SNA
12h 38m2 stops
$460Frontier
Find Deal
Mon, Nov 10 - Fri, Nov 14
Frontier Logo
12:01 pm - 10:45 amSNA-MEX
20h 44m2 stops
Frontier Logo
8:10 am - 6:48 pmMEX-SNA
12h 38m2 stops
$481Frontier
Find Deal
Booking Insights

KAYAK's insights & trends for Santa Ana to Mexico City Federal District flights

Get data-powered insights and trends into flights from Santa Ana to Mexico City Federal District to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Ana to Mexico City Federal District?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Mexico City Federal District, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Mexico City Federal District is March, when tickets cost $553 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $790 and $779 respectively.

Good to know

Low seasonMay
Cheapest flight$143
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from John Wayne (Santa Ana) to Mexico City

FAQs - booking Mexico City Federal District flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Mexico City Federal District?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Mexico City Federal District.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Mexico City Federal District?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Mexico City Federal District is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Mexico City Federal District?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Mexico City Federal District with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Mexico City Federal District?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Mexico City Federal District up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Mexico City Federal District?

    The cheapest time of day to fly to Mexico City Federal District is generally at night, when round-trip flights cost $485 on average. Morning departures are around 21% more expensive than evening flights, on average. The most expensive time of day to fly to Mexico City Federal District is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $850.

Reviews of the top airlines flying from Santa Ana to Mexico City Federal District

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Mexico City Federal District. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Mexico City Federal District? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7957 reviews
7.9Entertainment
7.3Food
7.9Comfort
8.2Boarding
8.5Crew
Airline reviews

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

2.0 MediocreAnonymous, Sep 2025SNA - SEA
Read more Delta reviews

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

Crew was excellent. Comfort seats not as nice as other kinds of planes.

It was a great flight and the stewards and stewardess were all kind and accommodating!! The seats were comfortable and entertainment screen excellent!

Overpriced tickets and attitudes to pay for such service. So bummed.

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

There was a security issue at the airport and we were unable to land. We circled endlessly and then landed at another airfield for fuel. We then circled the airport again, almost landed but didn’t fully touch down before circling again. I am thankful to the crew for keeping us safe- the issue was the airline and staff at the airport getting us seats on our connecting flights. That part was hours of searching for someone and getting in double my steps.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Was not able to watch most shows on the entertainment site. They would not load

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Delayed flight, so I switched fights to SFO to Phoenix , Phoenix to DSM. Excellent service through American Airlines

AA re-routed flight from HNL to LAX due to delay. My group of 3 with reserved seats in row 9 was broken up, with one assigned to a middle seat, another in the last row of the plane. Not happy. No explanation to the delay. No apologies. No compensation. Would have been nice to be offered an Admiral Club admission or a voucher for the extra 3 hours of layover in LAX. Could not hear the boarding gate announcements in LAX. Adjacent gate was boarding at the same time. Loud speakers were competing against each other. Barely made my boarding group.

Almost a 6 hour flight and the only food option is a cheese plate… and chips. Also how is it there are no options for texting on American. I’ll be going back to delta and united.

Bad food, small seats that didn’t recline. I thought I was buying a quantas ticket so I feel like I got scammed

Everything you need to know for your flight from Santa Ana to Mexico City Federal District

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.