$143 Find Cheap Flights from John Wayne (Santa Ana) to Mexico City Federal District - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Mexico City Federal District departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City Federal District

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Mexico City Federal District, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Mexico City Federal District, as well as popular online travel agencies
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Book Cheap Santa Ana to Mexico City Federal District Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Mexico City Federal District that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Mexico City Federal District

Mon, Aug 24 - Fri, Sep 18
Multiple Airlines Logo
2:27 pm - 8:00 pm
SNA
-
MEX
28h 33m
2 stops
Multiple Airlines Logo
11:00 am - 5:35 pm
MEX
-
SNA
7h 35m
1 stop
$352Multiple Airlines
Mon, Aug 24 - Fri, Sep 18
Multiple Airlines Logo
6:39 pm - 10:45 pm
SNA
-
MEX
27h 06m
1 stop
Multiple Airlines Logo
11:00 am - 5:35 pm
MEX
-
SNA
7h 35m
1 stop
$387Multiple Airlines
Mon, Oct 5 - Mon, Oct 12
Multiple Airlines Logo
4:50 pm - 8:05 pm
SNA
-
MEX
26h 15m
1 stop
Multiple Airlines Logo
11:00 am - 3:03 pm
MEX
-
SNA
29h 03m
1 stop
$401Multiple Airlines
Mon, Oct 5 - Wed, Oct 14
Multiple Airlines Logo
2:27 pm - 8:00 pm
SNA
-
MEX
28h 33m
2 stops
Multiple Airlines Logo
11:00 am - 5:40 pm
MEX
-
SNA
7h 40m
1 stop
$402Multiple Airlines
Wed, Jul 15 - Wed, Aug 12
Multiple Airlines Logo
4:13 pm - 9:45 pm
SNA
-
MEX
28h 32m
1 stop
Multiple Airlines Logo
6:20 am - 12:31 pm
MEX
-
SNA
31h 11m
2 stops
$406Multiple Airlines
Tue, Oct 6 - Wed, Oct 14
Multiple Airlines Logo
7:30 am - 8:05 pm
SNA
-
MEX
11h 35m
1 stop
Multiple Airlines Logo
11:00 am - 5:40 pm
MEX
-
SNA
7h 40m
1 stop
$408Multiple Airlines
Wed, Jul 15 - Wed, Aug 12
Multiple Airlines Logo
4:13 pm - 9:45 pm
SNA
-
MEX
28h 32m
1 stop
Multiple Airlines Logo
11:55 am - 12:31 pm
MEX
-
SNA
25h 36m
1 stop
$416Multiple Airlines
Wed, Oct 7 - Wed, Oct 14
Multiple Airlines Logo
7:30 am - 9:45 pm
SNA
-
MEX
13h 15m
1 stop
Multiple Airlines Logo
11:00 am - 5:40 pm
MEX
-
SNA
7h 40m
1 stop
$420Multiple Airlines
Tue, Jul 7 - Fri, Jul 10
Multiple Airlines Logo
4:13 pm - 9:45 pm
SNA
-
MEX
28h 32m
1 stop
Multiple Airlines Logo
11:00 am - 12:31 pm
MEX
-
SNA
26h 31m
1 stop
$428Multiple Airlines
Thu, Oct 8 - Wed, Oct 14
Multiple Airlines Logo
7:30 am - 8:05 pm
SNA
-
MEX
11h 35m
1 stop
Multiple Airlines Logo
11:00 am - 5:40 pm
MEX
-
SNA
7h 40m
1 stop
$429Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Mexico City Federal District flights

Get data-powered insights and trends into flights from Santa Ana to Mexico City Federal District to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from John Wayne (Santa Ana) to Mexico City Federal District?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Mexico City Federal District, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Mexico City Federal District is November, when tickets cost $269 (return) on average. On the other hand, the most expensive months are August and December, when the average cost of round-trip tickets is $965 and $906 respectively.

Good to know

Low seasonMarch
Cheapest flight$143
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from John Wayne (Santa Ana) to Mexico City

FAQs - booking Mexico City Federal District flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Mexico City Federal District?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Mexico City Federal District.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Mexico City Federal District?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Mexico City Federal District is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Mexico City Federal District?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Mexico City Federal District with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Mexico City Federal District?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Mexico City Federal District up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Mexico City Federal District

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Mexico City Federal District. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Mexico City Federal District? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9893 reviews
7.7Boarding
7.1Entertainment
7.3Comfort
8.1Crew
6.6Food
Airline reviews

I needed internet for critical matters and it never worked.

2.0 MediocreJorge Luis, Jun 2026
DEN - MEX
Read more United Airlines reviews

I needed internet for critical matters and it never worked.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Terrible! After boarding we were stuck on the plane for 3 hours with no air circulation during a heat wave.

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

the head jack on my seat didn't work and the power outlet didn't work for my seat

All planes flying to Mexico City are very old. Seats don’t even have power outlets.

The flight was very smooth and the meal in business class was great.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

Delayed multiple times. Boarding was ok but getting off the aircraft was a mess. So disorganized with staff trying to help the elderly but completely blocking path for anyone else to move. Bathroom was disgusting, probably caused by one of the customers but staff couldn't care less to help clean it. No one wanted to use it since the floor was completely soaked so everyone just lined up the other restroom while the staff just chit chat with each other while looking at us.

I think the seats on some of their planes are uncomfortable. You can be ok on a short flight of two hours but no more than that. The delays, and also the refreshments on the plane were not enough.

Terrible, oxygen masks were deployed mid-flight. We returned to airport. Took additional 12 hours to get home.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

Everything you need to know for your flight from Santa Ana to Mexico City Federal District

Information on your arrival and departure airports