$100 Find Cheap Flights from John Wayne (Santa Ana) to Mississippi

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Mississippi departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Mississippi, as well as popular online travel agencies
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Cheap Flights from Santa Ana to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson2 stops$363
Gulfport
Gulfport1 stop$321
Memphis
Memphis1 stop$221
Jackson
Jackson2 stops$363
Gulfport
Gulfport1 stop$321
Memphis
Memphis1 stop$221

Book Cheap Santa Ana to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Mississippi

Thu, Oct 29 - Mon, Nov 2
Multiple Airlines Logo
4:46 pm - 12:14 pm
SNA
-
MEM
17h 28m
1 stop
Multiple Airlines Logo
1:29 pm - 3:03 pm
MEM
-
SNA
27h 34m
1 stop
$221Multiple Airlines
Fri, Sep 11 - Mon, Sep 14
Breeze Airways Logo
7:30 am - 6:06 pm
SNA
-
GPT
8h 36m
1 stop
Breeze Airways Logo
9:36 am - 4:15 pm
GPT
-
SNA
8h 39m
1 stop
$321Breeze Airways
Tue, Sep 1 - Sat, Sep 5
American Airlines Logo
9:07 am - 6:04 pm
SNA
-
GPT
6h 57m
1 stop
American Airlines Logo
5:31 am - 9:42 am
GPT
-
SNA
6h 11m
1 stop
$331American Airlines
Tue, Sep 1 - Sat, Sep 5
Delta Logo
8:11 am - 10:21 pm
SNA
-
GPT
12h 10m
2 stops
Delta Logo
4:00 pm - 9:56 pm
GPT
-
SNA
7h 56m
1 stop
$336Delta
Tue, Sep 1 - Sat, Sep 5
United Airlines Logo
6:45 am - 7:38 pm
SNA
-
GPT
10h 53m
2 stops
United Airlines Logo
4:59 pm - 9:45 pm
GPT
-
SNA
6h 46m
1 stop
$345United Airlines
Thu, Aug 20 - Mon, Aug 24
Delta Logo
2:00 pm - 11:06 pm
SNA
-
MOB
7h 06m
1 stop
Delta Logo
4:37 pm - 9:56 pm
MOB
-
SNA
7h 19m
1 stop
$349Delta
Sat, Aug 29 - Mon, Aug 31
United Airlines Logo
8:13 am - 4:12 pm
SNA
-
GPT
5h 59m
1 stop
United Airlines Logo
4:59 pm - 9:45 pm
GPT
-
SNA
6h 46m
1 stop
$359United Airlines
Tue, Oct 13 - Tue, Oct 20
Southwest Logo
7:00 am - 8:00 pm
SNA
-
JAN
11h 00m
2 stops
Southwest Logo
1:05 pm - 7:30 pm
JAN
-
SNA
8h 25m
2 stops
$363Southwest
Sat, Aug 15 - Tue, Aug 18
American Airlines Logo
2:29 pm - 10:50 pm
SNA
-
MEM
6h 21m
1 stop
American Airlines Logo
9:30 am - 1:30 pm
MEM
-
SNA
6h 00m
1 stop
$375American Airlines
Mon, Nov 2 - Mon, Nov 9
Southwest Logo
10:45 am - 10:05 pm
SNA
-
JAN
9h 20m
2 stops
Southwest Logo
5:35 am - 12:45 pm
JAN
-
SNA
9h 10m
2 stops
$383Southwest
Booking Insights

KAYAK's insights & trends for Santa Ana to Mississippi flights

Get data-powered insights and trends into flights from Santa Ana to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Mississippi were found on United Airlines ($345) and Delta ($349).

Good to know

Low seasonFebruary
Cheapest flight$100
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 24% increase in price.
Flight from John Wayne (Santa Ana) to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11762 reviews
7.2Comfort
6.8Entertainment
7.9Crew
6.4Food
7.5Boarding
Airline reviews

Flight was delayed multiple times without giving any particular reason and the only thing that was communicated was that 'Aircraft is getting ready'. I was stuck at SFO airport for 15 hours and finally took Southwest Airlines flight back home to Dallas.

2.0 MediocreAnil, Jun 2026
SFO - DFW
Read more American Airlines reviews

Flight was delayed multiple times without giving any particular reason and the only thing that was communicated was that 'Aircraft is getting ready'. I was stuck at SFO airport for 15 hours and finally took Southwest Airlines flight back home to Dallas.

I was not clear if food was offered or not.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

American was having a problem with their kiosks when I arrived which made the check-in and bag drop process unusually long. Additionally, they only had one person working check-in. Eventually, the kiosks were fixed and everything else went smoothly.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

The flight was short. However, my bag was delayed and was put on another flight.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

Everything you need to know for your flight from Santa Ana to Mississippi

Information on your arrival and departure airports