$150 Find Cheap Flights from Santa Ana to Mississippi

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Mississippi departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Mississippi, as well as popular online travel agencies
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Cheap Flights from Santa Ana to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson2 stops$364
Gulfport
Gulfport1 stop$524
Columbus
Columbus1 stop$576
Memphis
Memphis1 stop$166
Jackson
Jackson2 stops$364
Gulfport
Gulfport1 stop$524
Columbus
Columbus1 stop$576
Memphis
Memphis1 stop$166

Book Cheap Santa Ana to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Mississippi

Fri, Apr 17 - Mon, Apr 20
Multiple Airlines Logo
6:45 am - 8:27 pm
SNA
-
MEM
11h 42m
1 stop
Multiple Airlines Logo
9:17 pm - 3:40 pm
MEM
-
SNA
20h 23m
1 stop
$166Multiple Airlines
Thu, Feb 26 - Mon, Mar 2
Multiple Airlines Logo
1:20 pm - 8:27 pm
SNA
-
MEM
29h 07m
1 stop
Multiple Airlines Logo
9:17 pm - 3:42 pm
MEM
-
SNA
20h 25m
1 stop
$213Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
8:20 pm - 8:27 pm
SNA
-
MEM
22h 07m
1 stop
Multiple Airlines Logo
8:30 pm - 10:46 am
MEM
-
SNA
16h 16m
2 stops
$231Multiple Airlines
Sat, Apr 11 - Sat, Apr 18
United Airlines Logo
3:29 pm - 10:45 pm
SNA
-
BTR
5h 16m
1 stop
United Airlines Logo
5:00 am - 11:13 am
BTR
-
SNA
8h 13m
1 stop
$309United Airlines
Wed, Apr 1 - Sat, Apr 25
United Airlines Logo
3:29 pm - 10:45 pm
SNA
-
BTR
5h 16m
1 stop
United Airlines Logo
9:20 am - 5:23 pm
BTR
-
SNA
10h 03m
2 stops
$314United Airlines
Sat, Mar 7 - Tue, Mar 10
American Airlines Logo
2:48 pm - 10:39 pm
SNA
-
BTR
5h 51m
1 stop
American Airlines Logo
5:00 am - 10:05 am
BTR
-
SNA
7h 05m
1 stop
$334American Airlines
Fri, May 8 - Tue, May 12
Delta Logo
12:20 pm - 10:00 pm
SNA
-
BTR
7h 40m
1 stop
Delta Logo
3:48 pm - 10:38 pm
BTR
-
SNA
8h 50m
1 stop
$344Delta
Thu, Mar 19 - Tue, Mar 24
Delta Logo
9:20 pm - 8:31 am
SNA
-
MOB
9h 11m
1 stop
Delta Logo
12:42 pm - 7:42 pm
MOB
-
SNA
9h 00m
1 stop
$359Delta
Wed, Apr 1 - Sat, Apr 25
American Airlines Logo
8:17 am - 3:58 pm
SNA
-
BTR
5h 41m
1 stop
American Airlines Logo
2:33 pm - 6:29 pm
BTR
-
SNA
5h 56m
1 stop
$407American Airlines
Tue, Mar 17 - Tue, Mar 24
Southwest Logo
8:10 am - 6:35 pm
SNA
-
JAN
8h 25m
2 stops
Southwest Logo
5:50 am - 1:30 pm
JAN
-
SNA
9h 40m
2 stops
$410Southwest
Booking Insights

KAYAK's insights & trends for Santa Ana to Mississippi flights

Get data-powered insights and trends into flights from Santa Ana to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Ana to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to Mississippi were found on United Airlines ($309) and American Airlines ($309).

Find deals

Good to know

Low seasonSeptember
Cheapest flight$150
Best time to beat the crowds with an average 29% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from John Wayne (Santa Ana) to Gulfport

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11288 reviews
7.5Boarding
6.9Entertainment
7.2Comfort
8.0Crew
6.4Food
Airline reviews

Flight was delayed for 2 hours, then last minute the change to on time. The satélite location is far and a nightmare to get to.

4.0 OkayFrancisco, Feb 2026
LAX - SAF
Read more American Airlines reviews

Flight was delayed for 2 hours, then last minute the change to on time. The satélite location is far and a nightmare to get to.

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

For a 5 1/2 hour flite i considered the "business class" to be subpar. The seats were just ok, no amenities, really nothing more than a long domestic flight. Frankly disappointed.

It would be nice to have some low carb options in the snacks.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

The flight was flawless and we even arrived between 20 and 25 minutes early!

Everything you need to know for your flight from Santa Ana to Mississippi

Information on your arrival and departure airports

John Wayne (Santa Ana) (SNA)