$188 Find Cheap Flights from John Wayne (Santa Ana) to Mississippi - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Jackson
Jackson1 stop$390
Gulfport
Gulfport1 stop$341
Columbus
Columbus1 stop$579
Memphis
Memphis1 stop$266
Jackson
Jackson1 stop$390
Gulfport
Gulfport1 stop$341
Columbus
Columbus1 stop$579
Memphis
Memphis1 stop$266
Booking Insights

KAYAK's insights & trends for Santa Ana to Mississippi flights

Get data-powered insights and trends into flights from Santa Ana to Mississippi to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from John Wayne (Santa Ana) to Mississippi?

The cheapest month for flights from John Wayne (Santa Ana) to Mississippi is July, when tickets cost $0 (return) on average. On the other hand, the most expensive months are January and May, when the average cost of round-trip tickets is $912 and $849 respectively.

Good to know

Low season

February

Cheapest flight

$188
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly with an average 36% increase in price.
Flight from John Wayne (Santa Ana) to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Mississippi

 
Need help choosing which airline to fly with from Santa Ana to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11969 reviews
7.2Comfort
6.4Food
6.8Entertainment
7.5Boarding
7.9Crew
Airline reviews

More space for economy, and the bathroom size is only for people with size XS

10.0 ExcellentDariya, Aug 2026
Read more American Airlines reviews

More space for economy, and the bathroom size is only for people with size XS

The WiFi didn’t work entire flight, couldn’t watch a movie. The recline button didn’t work

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

American was having a problem with their kiosks when I arrived which made the check-in and bag drop process unusually long. Additionally, they only had one person working check-in. Eventually, the kiosks were fixed and everything else went smoothly.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

The flight was short. However, my bag was delayed and was put on another flight.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

Everything you need to know for your flight from Santa Ana to Mississippi

Information on your arrival and departure airports