$344 Find Cheap Flights from John Wayne (Santa Ana) to Spain

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Spain departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Spain

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Madrid
Madrid1 stop$749
Málaga
Málaga1 stop$863
Ibiza
Ibiza2 stops$1,129
Valencia
Valencia2 stops$781
Seville
Seville2 stops$1,063
Bilbao
Bilbao2 stops$1,008
Alicante
Alicante2 stops$1,116
San Sebastian
San Sebastian2 stops$1,474
Madrid
Madrid1 stop$749
Málaga
Málaga1 stop$863
Ibiza
Ibiza2 stops$1,129
Valencia
Valencia2 stops$781
Seville
Seville2 stops$1,063
Bilbao
Bilbao2 stops$1,008
Alicante
Alicante2 stops$1,116
San Sebastian
San Sebastian2 stops$1,474

Book Cheap Santa Ana to Spain Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Spain that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Spain

Tue, Aug 18 - Tue, Sep 15
British Airways Logo
6:45 am - 9:05 am
SNA
-
MAD
17h 20m
1 stop
British Airways Logo
1:35 pm - 9:09 pm
MAD
-
SNA
16h 34m
1 stop
$749British Airways
Sun, Oct 4 - Wed, Oct 14
American Airlines Logo
2:29 pm - 2:25 pm
SNA
-
MAD
14h 56m
1 stop
American Airlines Logo
11:45 am - 9:13 pm
MAD
-
SNA
18h 28m
1 stop
$764American Airlines
Sun, Oct 4 - Wed, Oct 14
KLM Logo
12:20 pm - 12:15 pm
SNA
-
MAD
14h 55m
1 stop
KLM Logo
6:00 am - 5:59 pm
MAD
-
SNA
20h 59m
2 stops
$766KLM
Sun, Oct 4 - Wed, Oct 14
Delta Logo
7:45 am - 3:35 pm
SNA
-
MAD
22h 50m
2 stops
Delta Logo
6:00 am - 10:24 pm
MAD
-
SNA
25h 24m
2 stops
$770Delta
Wed, Oct 21 - Mon, Nov 9
United Airlines Logo
7:00 am - 8:05 am
SNA
-
MAD
16h 05m
2 stops
United Airlines Logo
1:45 pm - 8:19 pm
MAD
-
SNA
39h 34m
2 stops
$807United Airlines
Tue, Oct 13 - Tue, Oct 27
United Airlines Logo
7:59 pm - 10:35 pm
SNA
-
VLC
41h 36m
2 stops
United Airlines Logo
1:00 pm - 9:15 am
VLC
-
SNA
28h 15m
3 stops
$946United Airlines
Mon, Jul 13 - Thu, Jul 23
Delta Logo
11:40 am - 6:40 pm
SNA
-
AGP
22h 00m
2 stops
Delta Logo
12:40 pm - 10:28 am
AGP
-
SNA
30h 48m
2 stops
$965Delta
Tue, May 26 - Thu, Jul 2
KLM Logo
2:00 pm - 4:35 pm
SNA
-
AGP
17h 35m
2 stops
KLM Logo
11:35 pm - 4:33 pm
AGP
-
SNA
25h 58m
2 stops
$981KLM
Mon, Oct 12 - Wed, Oct 21
Iberia Logo
10:35 am - 10:10 am
SNA
-
BCN
14h 35m
1 stop
Iberia Logo
1:30 pm - 9:51 pm
BCN
-
SNA
17h 21m
1 stop
$1,065Iberia
Mon, Oct 12 - Wed, Oct 21
Iberia Logo
10:35 am - 10:10 am
SNA
-
BCN
14h 35m
1 stop
Iberia Logo
8:50 am - 7:39 pm
BCN
-
SNA
19h 49m
2 stops
$1,076Iberia
Booking Insights

KAYAK's insights & trends for Santa Ana to Spain flights

Get data-powered insights and trends into flights from Santa Ana to Spain to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from John Wayne (Santa Ana) to Spain?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Spain, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Spain is September, when tickets cost $458 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $1,186 and $965 respectively.

Good to know

Low seasonNovember
Cheapest flight$344
Best time to beat the crowds with an average 42% drop in price.
Most popular time to fly and prices are also 20% lower on average.
Flight from John Wayne (Santa Ana) to Madrid

FAQs - booking Spain flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Spain?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Spain.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Spain?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Spain is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Spain?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Spain with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Spain?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Spain up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santa Ana to Spain

 
Need help choosing which airline to fly with from Santa Ana to Spain? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9681 reviews
7.3Comfort
8.1Crew
7.7Boarding
6.6Food
7.1Entertainment
Airline reviews

Some crew were unfriendly or in some cases just straight up rude.

6.0 GoodAnonymous, Apr 2026
SFO - YVR
Read more United Airlines reviews

Some crew were unfriendly or in some cases just straight up rude.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Food was surprisingly delicious. Space in the seat is horrible when the seating front is reclined. Movie offerings were terrible. Crew was friendly and helpful.

Flight itself excellent, but delayed so missed connection & got to destination 2 hrs later

Due to cancellation of connecting flight (Lufthansa) I didn’t fly with United

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Boarding gate at LAX was too crowded—two gates next to one another

On time departure and early arrival. Flight attendant very nice.

The business class layout of chairs was weired. You are sitting directly across stranger.,

The SFO Lounge crew were amazing. The bartender Faris was great. Thanks!

Friendly crew is the only nice thing. Seats uncomfortable. Food and snacks horrible. Movies were the same as the first 10 hour flight two weeks before

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

Good flight, seated and had a water within 5 minutes. Crew was hospitable.

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

I cancelled my ticket less than 24 hours deadline but I didn’t get refunded.

Service was good , communication and emails were in Spanish though I booked in English , end up figuring it out but also flight was partnered with air maroc and I had to call them to check on not Iberea doesn’t make sense

In general, I've had excellent experiences with Iberia flights and will continue to use them. In this last flight there were two things that didn't go right. I didn't get the kosher meal I had pre-requested when I had checked in on-line. Things worked out OK as we ended up eating the fish and vegetarian choices, which were really good. The other issue was that some movies for me and my wife started fine but after 8-12 minutes the content just switched to something else. The flight attendant reset our entertainment systems, but the problem persisted. We ended up choosing other movies/TV shows that did work fine.

Awful. They didn't even show concern that her connecting flight( Dallas to Mardrid) was gone/missing. I don't understand how that is even possible. Rudest answer from one of the crew was that American Airlines sold the tickets to somebody else. My daughter was not in the list.

The flight was canceled on a Thursday last minute. I lost thousands of dollars in hotels and car rental

Excellent lie flat seat for premium economy! Great staff. Bad food . Not so great entertainment. My bag didn’t make it either.

Really like the idea experience on this airline I will use again

The pilot was professional and very good. The flight crew, very young and often looked flustered and overwhelmed. The seats were among the most uncomfortable in the air. The boarding somewhat chaotic. The price reasonable. Overall it was an average budget airline experience...although Iberia is not a budget airline. I fear if Iberia doesn't up it's game customers like us will go elsewhere.

Bad weather Excelent pilot Spoke British 😆on time seats small ad expected in a discount airline

It wasn’t great because the third-party from Kayak there was just no information about how to check in with Vueling. And the purchase of the ticket from under pricer just made everything really difficult. I’m unlikely to use Kayak again for these reasons.

It was fine, older plane with limited entertainment, otherwise fine.

Boarding was orderly, pilot and flight attendants were nice, entertainment options were good, and low sodium meals were quite tasty.

Flight delayed, connection was not at gate listed and so missed, staff were rude at Heathrow, phone tree stupid and difficult, took me 21 actual hours to reach my destination. Almost lost my hotel reservation after walking in a strange city alone after midnight because they would not put me up in a hotel at sfo or heathrow. I will never fly BA again and will tell all people and Instagram followers never to fly BA.

Check-in in SAN was long. ORD was good. Flight delayed On board crew was ok. No warmth or personality. LHrR barely made connection

Wish the food and overall service was better. They treat Business class passengers same as economy

They had us seating down for one hour just waiting on the plane

Flying with BA is always a good experience—even in economy class. It is better if in business and first class. Timely, breeze through security and timely connections

The issue was not with BA it was with the link yoiu sent fopr booking the flight

Loved the boarding option from Business class lounge, experience on flight was excellent, plenty of good food choices

Awful it always is unfortunately is the only way to fly direct to london

Check in was was and the agent was very friendly and helpful The lounge was nice...boarding was straight from the lounge Everything worked at our seats, and video entertainment was good ..food was mediocre

Everything you need to know for your flight from Santa Ana to Spain

Information on your arrival and departure airports