$319 Find Cheap Flights from Santa Ana to Spain

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Spain departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Spain

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Madrid
Madrid2 stops$511
Málaga
Málaga2 stops$576
Seville
Seville2 stops$979
Valencia
Valencia2 stops$526
Ibiza
Ibiza2 stops$833
Bilbao
Bilbao2 stops$489
Alicante
Alicante2 stops$898
San Sebastian
San Sebastian2 stops$1,457
Madrid
Madrid2 stops$511
Málaga
Málaga2 stops$576
Seville
Seville2 stops$979
Valencia
Valencia2 stops$526
Ibiza
Ibiza2 stops$833
Bilbao
Bilbao2 stops$489
Alicante
Alicante2 stops$898
San Sebastian
San Sebastian2 stops$1,457

Book Cheap Santa Ana to Spain Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Spain that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Spain

Tue, Apr 14 - Thu, Apr 23
United Airlines Logo
6:45 am - 11:25 pm
SNA
-
BIO
31h 40m
2 stops
United Airlines Logo
6:50 am - 10:30 pm
BIO
-
SNA
24h 40m
2 stops
$489United Airlines
Sat, Apr 11 - Tue, Apr 21
United Airlines Logo
6:28 pm - 5:00 pm
SNA
-
BIO
37h 32m
2 stops
United Airlines Logo
6:50 am - 8:55 pm
BIO
-
SNA
23h 05m
2 stops
$502United Airlines
Sun, Apr 12 - Tue, Apr 21
British Airways Logo
4:23 pm - 9:40 am
SNA
-
MAD
32h 17m
2 stops
British Airways Logo
1:00 pm - 8:12 pm
MAD
-
SNA
16h 12m
1 stop
$511British Airways
Tue, Apr 14 - Tue, Apr 28
British Airways Logo
1:30 pm - 5:30 pm
SNA
-
MAD
19h 00m
2 stops
British Airways Logo
1:35 pm - 9:13 pm
MAD
-
SNA
16h 38m
1 stop
$512British Airways
Mon, Mar 2 - Wed, Mar 11
Air Canada Logo
12:25 pm - 8:00 am
SNA
-
MAD
58h 35m
2 stops
Air Canada Logo
12:40 pm - 11:25 am
MAD
-
SNA
54h 45m
2 stops
$516Air Canada
Mon, Mar 2 - Tue, Mar 17
Delta Logo
9:20 pm - 9:15 am
SNA
-
MAD
26h 55m
1 stop
Delta Logo
9:00 am - 9:55 pm
MAD
-
SNA
20h 55m
2 stops
$517Delta
Sun, Mar 8 - Wed, Mar 18
Air Canada Logo
12:25 pm - 7:00 am
SNA
-
MAD
58h 35m
2 stops
Air Canada Logo
12:40 pm - 11:25 am
MAD
-
SNA
54h 45m
2 stops
$518Air Canada
Tue, Apr 14 - Tue, Apr 21
American Airlines Logo
2:42 pm - 2:25 pm
SNA
-
MAD
14h 43m
1 stop
American Airlines Logo
3:55 pm - 8:28 am
MAD
-
SNA
25h 33m
1 stop
$525American Airlines
Fri, Apr 24 - Tue, Apr 28
Iberia Logo
1:23 pm - 5:00 pm
SNA
-
IBZ
18h 37m
2 stops
Iberia Logo
9:40 pm - 8:12 pm
IBZ
-
SNA
31h 32m
2 stops
$833Iberia
Mon, Apr 13 - Tue, Apr 21
Iberia Logo
2:42 pm - 5:00 pm
SNA
-
IBZ
17h 18m
2 stops
Iberia Logo
9:40 pm - 8:12 pm
IBZ
-
SNA
31h 32m
2 stops
$847Iberia
Booking Insights

KAYAK's insights & trends for Santa Ana to Spain flights

Get data-powered insights and trends into flights from Santa Ana to Spain to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Santa Ana and Spain?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Santa Ana to Spain.

There are 2 airlines that fly nonstop from Santa Ana to Spain. They are Iberia and British Airways. The cheapest airline for this route is British Airways, with the best round-trip deal found costing $491 and arriving in Madrid (MAD). On average, British Airways offers the best prices for nonstop flights between Santa Ana and Spain.

Which airlines provide the cheapest flights from Santa Ana to Spain?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to Spain were found on United Airlines ($489) and British Airways ($511).

Good to know

Low seasonAugust
Cheapest flight$319
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 25% lower on average.
Flight from John Wayne (Santa Ana) to Barcelona

FAQs - booking Spain flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Spain?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Spain.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Spain?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Spain is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Spain?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Spain with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Spain?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Spain up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santa Ana to Spain

 
Need help choosing which airline to fly with from Santa Ana to Spain? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9215 reviews
7.1Entertainment
7.3Comfort
8.1Crew
6.6Food
7.7Boarding
Airline reviews

The food was terrible this time. Otherwise pleasant, quiet, on-time.

8.0 ExcellentAnonymous, Jan 2026
SAN - MUC
Read more United Airlines reviews

The food was terrible this time. Otherwise pleasant, quiet, on-time.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

The flight crew where really good. Better then the crew from BNE to SFO

Food should be changed in menu Many muslims travels in this airlime they need to add one Halal meal

left on time, reasonable boarding process arrived early luggage came out quickly

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

I boarded flight UA#1318 at Sacramento International Airport going back to Houston TX. The flight was scheduled at 5:10am. I was able to check in virtually using the United Airlines app. When I entered the airport, there was no one outside assisting with checked bags as it was for Delta Airlines. Immediately upon entering, there was a LONG, EXTREMELY LONG line to the kiosks to get boarding passes. I stand in line to get boarding passes then had to move to ANOTHER EXTREMELY LONG line to get my bags checked in. While standing in this line, we noticed an agent taking customers to 3 at a time to her station to check their bags in. Lucky for me, she called me back, checked my bags for me and I was on my way. I then encountered another long line at the TSA check and to avoid I ending up having to sign up for CLEAR to bypass it. So glad, I did.,...Both of my flights were great with no issues, butthe check in progress at Bush Airport was so much smoother. Check-in at SMF airport needs to be anaylzed and corrected. Do better United, I know you can....thanks

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

While I didn’t watch much tv I would have liked a few more options of TV series from Apple TV or hbo max ..

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

The flight was very smooth and the meal in business class was great.

I requested a low sodium meal. Reason being, I take medicine for high blood pressure and I wear compression socks on long flights to help with leg swelling. Having less sodium in meals really helps me feel better on long flights. I received my initial low sodium meal after takeoff. Just before landing, the crew came through with the meal cart and offered me what was being served. I said no thank you and then noticed my low sodium meal in the meal cart, with my name and seat assignment on it. I motioned to the crew member, but he grabbed the meal cart and proceeded to move to the rear of the aircraft. He didn’t see me or other passengers who had attempted to get this attention. He was more concerned about completing meal service since we were due to land in under 45 minutes. I pressed the call light five times from my seat to receive help, but no crew member responded to me. So, I didn’t receive a second meal, one that I requested (the low sodium option). This led me to have a migraine from only eating one meal on an 11-hour flight. This is why I’m not a fan of flying US-based airlines overseas. The crew members continue to show the absolute worst customer service experience. I would not recommend flying American for overseas flights.

Not great. Booked Extra seats and got nothing extra at all. It’s basically a big budget airline.

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

The flight was flawless and we even arrived between 20 and 25 minutes early!

The pilot was professional and very good. The flight crew, very young and often looked flustered and overwhelmed. The seats were among the most uncomfortable in the air. The boarding somewhat chaotic. The price reasonable. Overall it was an average budget airline experience...although Iberia is not a budget airline. I fear if Iberia doesn't up it's game customers like us will go elsewhere.

Bad weather Excelent pilot Spoke British 😆on time seats small ad expected in a discount airline

It wasn’t great because the third-party from Kayak there was just no information about how to check in with Vueling. And the purchase of the ticket from under pricer just made everything really difficult. I’m unlikely to use Kayak again for these reasons.

It was fine, older plane with limited entertainment, otherwise fine.

the seats were bad and uncomfortable and the food was not tasty.

the seats were so cramped you could barely move. it was difficult to eat when passengers would recline their seats. the seats were so flimsy and unstable that whenever someone got in and out of their seat, it bounced like a spring back in your face. the movies were nice. the food was terrible. even though the conditions were terrible, they tried to pressure passengers to relocate their seats to accommodate adults who were related and wanted to sit next to each other, even after the passengers expressed that they did not want to move for that purpose. on the connecting flight, the “service” consisted of items for purchase. even though the flight was only 45 minutes, once again passengers (including me) were pressured to relocate for people to sit next to each other. they couldn’t be apart for 45 minutes? this was much less compelling than being apart for an 8 hour flight.

Everything went smoothly, and we even arrived 40min earlier than scheduled, on an Orland-Madrid route.

It was budget airline Veuling, even though we booked Iberia.

The staff was very nice and helpful. Some of the best crew I have met.

Bad experience. The seat room are very tight. The food is not good and the breakfast has no hot drink.

The issue was not with BA it was with the link yoiu sent fopr booking the flight

Loved the boarding option from Business class lounge, experience on flight was excellent, plenty of good food choices

Getting the boarding passes between the BA and AA apps was very clunky.

Awful it always is unfortunately is the only way to fly direct to london

Check in was was and the agent was very friendly and helpful The lounge was nice...boarding was straight from the lounge Everything worked at our seats, and video entertainment was good ..food was mediocre

Airlines have to stop assuming passengers bring entertainment. Provide it like you used to in business class and above!! N

I don't know about the others but the flight attendant that took care of us had the absolute wrong approach "how do we dare asking for water or anything else for that matter"

Need to offer Better food from LAX to London Service from London to Delhi very delayed after take off.

Great crew and food and beverage. Seating tight but not the airline's fault. Will definitely fly BA in future!

Crying baby the ENTIRE flight. Not your fault, but I paid 2700 for a premium economy ticket and it wasn't worth it. should have just stuck with coach. flight attendants very mediocre - minimal effort. Plane didn't seem very clean. Didn't have any cleansing wipes - most airlines give you this when you board. Flat screen scrolling didn't work. Toiletry case a joke - why bother at all?

Everything you need to know for your flight from Santa Ana to Spain

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