$337 Find Cheap Flights from John Wayne (Santa Ana) to Spain - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Spain departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Spain

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Madrid
Madrid1 stop$754
Málaga
Málaga2 stops$846
Valencia
Valencia2 stops$797
Ibiza
Ibiza2 stops$1,015
Seville
Seville2 stops$1,147
Bilbao
Bilbao2 stops$738
Alicante
Alicante2 stops$1,011
San Sebastian
San Sebastian2 stops$1,155
Madrid
Madrid1 stop$754
Málaga
Málaga2 stops$846
Valencia
Valencia2 stops$797
Ibiza
Ibiza2 stops$1,015
Seville
Seville2 stops$1,147
Bilbao
Bilbao2 stops$738
Alicante
Alicante2 stops$1,011
San Sebastian
San Sebastian2 stops$1,155

Book Cheap Santa Ana to Spain Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Spain that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Spain

Sun, Dec 6 - Thu, Dec 10
KLM Logo
11:40 am - 4:00 pm
SNA
-
BIO
19h 20m
2 stops
KLM Logo
8:30 am - 10:14 pm
BIO
-
SNA
22h 44m
2 stops
$738KLM
Sun, Sep 20 - Tue, Oct 6
United Airlines Logo
6:32 pm - 8:05 am
SNA
-
MAD
28h 33m
2 stops
United Airlines Logo
10:50 am - 10:27 am
MAD
-
SNA
32h 37m
1 stop
$754United Airlines
Sun, Sep 20 - Tue, Oct 6
Multiple Airlines Logo
8:45 am - 8:20 am
SNA
-
MAD
14h 35m
1 stop
Multiple Airlines Logo
3:55 pm - 11:00 am
MAD
-
SNA
28h 05m
1 stop
$754Multiple Airlines
Sun, Sep 20 - Tue, Oct 6
United Airlines Logo
6:32 pm - 8:05 am
SNA
-
MAD
28h 33m
2 stops
United Airlines Logo
10:50 am - 9:29 am
MAD
-
SNA
31h 39m
3 stops
$754United Airlines
Wed, Sep 23 - Fri, Sep 25
British Airways Logo
8:00 am - 9:05 am
SNA
-
MAD
16h 05m
1 stop
British Airways Logo
1:35 pm - 8:12 pm
MAD
-
SNA
15h 37m
1 stop
$761British Airways
Wed, Sep 23 - Tue, Oct 6
Iberia Logo
9:12 am - 9:05 am
SNA
-
MAD
14h 53m
1 stop
Iberia Logo
7:30 am - 8:16 pm
MAD
-
SNA
21h 46m
2 stops
$772Iberia
Thu, Sep 17 - Wed, Sep 30
American Airlines Logo
12:14 pm - 2:25 pm
SNA
-
MAD
17h 11m
1 stop
American Airlines Logo
3:55 pm - 8:17 am
MAD
-
SNA
25h 22m
1 stop
$809American Airlines
Tue, Nov 3 - Mon, Nov 16
British Airways Logo
1:10 pm - 7:45 am
SNA
-
MAD
33h 35m
1 stop
British Airways Logo
1:00 pm - 9:27 pm
MAD
-
SNA
17h 27m
1 stop
$824British Airways
Tue, Sep 29 - Tue, Oct 13
Iberia Logo
10:35 am - 10:10 am
SNA
-
BCN
14h 35m
1 stop
Iberia Logo
9:30 pm - 8:16 pm
BCN
-
SNA
31h 46m
2 stops
$852Iberia
Wed, Sep 9 - Wed, Sep 23
American Airlines Logo
6:45 am - 9:35 am
SNA
-
MAD
17h 50m
1 stop
American Airlines Logo
11:45 am - 8:12 pm
MAD
-
SNA
17h 27m
1 stop
$988American Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Spain flights

Get data-powered insights and trends into flights from Santa Ana to Spain to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from John Wayne (Santa Ana) to Spain?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Spain, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Spain is August, when tickets cost $0 (return) on average. On the other hand, the most expensive months are June and December, when the average cost of round-trip tickets is $1,585 and $1,300 respectively.

Good to know

Low season

March

Cheapest flight

$337
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 30% lower on average.
Flight from John Wayne (Santa Ana) to Madrid

FAQs - booking Spain flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Spain?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Spain.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Spain?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Spain is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Spain?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Spain with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Spain?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Spain up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santa Ana to Spain

 
Need help choosing which airline to fly with from Santa Ana to Spain? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10048 reviews
7.7Boarding
6.6Food
8.1Crew
7.1Entertainment
7.3Comfort
Airline reviews

The pilot was late so we didn’t take off til almost 2 hours late.

8.0 ExcellentAnonymous, Jul 2026
SFO - MNL
Read more United Airlines reviews

The pilot was late so we didn’t take off til almost 2 hours late.

Flight was late, the only reason I almost missed my flight was that my connection was also late.

Baggage claim signs were not updated with my flight information, so I had to guess. The app wasn't updated either.

It was a short, comfortable flight. It did leave an hour late due to the pilot having to be replaced (family emergency) but that didn’t inconvenience myself & my friend. The situation was explained, eventually.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

The best airline I have ever travel , really good customer service, attention and service !!

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

the head jack on my seat didn't work and the power outlet didn't work for my seat

My seat had a worn out cushion, which made it a bit uncomfortable. Other than that, the flight was excellent.

American was the airline that Starlux contracted for this trip. I arrived in time to make the connecting flight on American, and then the baggage-handler debacle happened. For some reason, the first class and premium economy passengers' luggage was unloaded first. Never seen this happen before. They had handlers removing the bags from the carousel for those passengers. Meanwhile, all of the economy passengers were waiting for their bags, including me. And there were a lot of bags because it was an international flight packed full. While waiting for 45 minutes, my bag didn't show. Meanwhile, an American representative showed up asking if anyone has a connecting flight to Phoenix. Of course I spoke up, and they proceeded to try to find my bag because I had to take a bus to the actual terminal to catch my flight. Which I was not informed of before I arrived. After another 15 minutes of searching, my bag was finally found with the first-class passengers' bags because they had pulled it by mistake. So I rushed to the terminal with the American representative to catch my flight, and they informed me that I missed it and could not get another flight until the next day. Of course, after being on an international flight for 18 hours, I was in no mood to hear this. Now, to be fair, there were a few American employees who tried to help me. After hearing about the missed flight, they got a supervisor to talk to. I expressed my situation to the supervisor, and she was not helpful until I asked for compensation. She agreed to get me a hotel room for the night. So I agreed, and she disappeared into her office, and I waited. And waited. And waited. And waited. While waiting, I was asked by three different employees who knew of my situation if I had been helped. I told them I was waiting for the supervisor to get the hotel room, and they said they would check. Finally, after waiting for 75 minutes, one of the employees who had asked me if I had been helped arrived with my hotel room and arranged a ride to the hotel for me. Never saw the supervisor again. It was now 8 o'clock; I arrived at 5:45! My rebooked fight was scheduled for 6:11 this morning and I have now been informed it has been delayed until 10:00. So am I happy with American? NO I'M NOT!! ;

The WiFi didn’t work entire flight, couldn’t watch a movie. The recline button didn’t work

The food was okay and the space in business class was smaller than we had to Singapore.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

We were bumped out of bulkhead seats we purchased a year ago. We were moved to row 5 and the folks in row 4 fully reclined making it difficult to get out to use the restroom. The seat have too little padding making them uncomfortable 3 hours into the flight. The movies did not offer closed captioning and the earbuds were poor so the entertainment was mostly unusable. The food was just passable. I would not fly Iberia/level again. Iberia also bumped us off our direct return flight so I would say the whole experience with this airline is poor.

Not bad but they lost 2 of my bags when I got to Florence

Couldn’t get boarding passes online, delayed an hour, and smallest amount of space on board I’ve ever encountered for such a long flight.

The crew were friendly and helpful. Iberia lost our luggage on arrival, Friday and we didn't get it until Sunday at 10:00 p.m. local Malaga time. I also paid $382.80 for seat assignments but two out out of the four were not together. Iberia mentioned that it was because the plane was delayed in Madrid before our flight began in LAX. They should compensate us half of my payment.

BEWARE!!! Iberia changes your seats at random. I paid for a window seat and they changed it to one in the middle aisle resting against the bathroom- can’t lean back + hear every flush. This on a 11 hour flight.. There were families that were broken up with separate seats all over the plane. Lots of upset passengers showing their seat confirmation to the besieged and helpless airline steward. Also, the gluten free meal was tasteless.

Flight delayed Service could be better Iberia staff are not really friendly

They cancelled the flight)(they said bad weather but many other flights took off) and made us wait 5 hours in line to figure out what to do. We ended up making a new flight the next day on another airlines...I hope they honor giving us our money back

We travelled with Level, which is a subsidiary of Iberia. They mixed up all our seats, downgraded few from premium economy fo economy. The crew were not professional, they seem to be in a rush! Also some with an attitude

Flight from Madrid to Dakar had no onboard entertainment for a business class. Not even a single screen . That was disappointing. The WiFi only worked for the first 45 mins of the flight.

No WIFI for the flight When told the breakfast item was cheese and tomato, did not mention sun dried tomotoes - totally different flavor and not what I wanted. Flyer for items for sale but none were offered.

I was booked in Premium Economy and never given a chance to choose to purchase my own seat. Ended up with a middle seat, which was very difficult for me. The airline then left my bag in London so when I arrived in Instanbul it was not there. They delivered it to me the next day but many valuable items had been stolen. I've been flying with BA for years and this was the first time I had such a bizarre and bad experience with them.

Canceled flight late London to Florence. Help at airport very poor. Treated poorly. Had to sleep in the airport. Lost bags- still do not have them. Horrible. I should be reimbursed!

Boarding was orderly, pilot and flight attendants were nice, entertainment options were good, and low sodium meals were quite tasty.

Flight delayed, connection was not at gate listed and so missed, staff were rude at Heathrow, phone tree stupid and difficult, took me 21 actual hours to reach my destination. Almost lost my hotel reservation after walking in a strange city alone after midnight because they would not put me up in a hotel at sfo or heathrow. I will never fly BA again and will tell all people and Instagram followers never to fly BA.

Check-in in SAN was long. ORD was good. Flight delayed On board crew was ok. No warmth or personality. LHrR barely made connection

Wish the food and overall service was better. They treat Business class passengers same as economy

They had us seating down for one hour just waiting on the plane

Flying with BA is always a good experience—even in economy class. It is better if in business and first class. Timely, breeze through security and timely connections

The issue was not with BA it was with the link yoiu sent fopr booking the flight

Loved the boarding option from Business class lounge, experience on flight was excellent, plenty of good food choices

Everything you need to know for your flight from Santa Ana to Spain

Information on your arrival and departure airports