STL - SCL

$564 Find Cheap Flights from St. Louis to Santiago - Compare and Save

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Everything you should know

Cheapest round-trip
$870
Typical prices: $858-$1,382
Multiple Airlines
Wed 10/31Wed 11/7
STL - SCL • 2 stops
Cheapest one-way
$564
Typical prices: $533-$713
Multiple Airlines
Sat 1/27
STL - SCL • 3 stops
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
July
Cheapest • 25% price drop
February
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Houston George Bush Intcntl (IAH)
Cheapest • Avg $1,025 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 13h 51m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from St. Louis to Santiago (STL-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santiago

Sat, Oct 31 - Sat, Nov 7
Multiple Airlines Logo
4:26 pm - 1:05 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
30h 39m2 stops Orlando Bogotá El Dorado
Multiple Airlines Logo
7:30 am - 11:19 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
30h 49m3 stops Bogotá El Dorado Orlando Dallas/Fort Worth
$870Multiple Airlines
Thu, Jan 28 - Mon, Feb 8
United Airlines Logo
3:03 pm - 8:50 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
14h 47m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 4:43 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
20h 58m1 stop Houston George Bush Intcntl
$995United Airlines
Wed, Jan 27 - Wed, Feb 3
United Airlines Logo
10:07 am - 8:50 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
19h 43m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 2:05 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
18h 20m1 stop Houston George Bush Intcntl
$995United Airlines
Fri, Dec 25 - Tue, Dec 29
LATAM Airlines Logo
4:49 pm - 7:40 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
11h 51m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
9:45 am - 9:07 amSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
26h 22m2 stops Miami Atlanta Hartsfield-Jackson
$997LATAM Airlines
Thu, Jan 28 - Sun, Feb 7
Delta Logo
3:40 pm - 6:40 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
12h 00m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:25 pm - 3:55 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
22h 30m2 stops Lima J Chavez Intl New York John F Kennedy Intl
$1,015Delta
Wed, Jan 27 - Thu, Feb 4
Delta Logo
1:01 pm - 3:00 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
22h 59m2 stops New York LaGuardia Lima J Chavez Intl
Delta Logo
8:25 pm - 2:43 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
21h 18m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,015Delta
Thu, Jan 28 - Fri, Feb 5
American Airlines Logo
9:00 am - 7:45 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
19h 45m1 stop Dallas/Fort Worth
American Airlines Logo
10:15 pm - 5:22 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
22h 07m1 stop Miami
$1,015American Airlines
Wed, Jan 27 - Fri, Feb 5
American Airlines Logo
9:51 am - 7:45 amSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
18h 54m1 stop Dallas/Fort Worth
American Airlines Logo
10:15 pm - 5:22 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
22h 07m1 stop Miami
$1,015American Airlines
Wed, Jan 27 - Wed, Feb 3
LATAM Airlines Logo
3:40 pm - 9:50 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
27h 10m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
4:10 am - 11:39 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
22h 29m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,015LATAM Airlines
Wed, Jan 27 - Mon, Feb 8
LATAM Airlines Logo
11:51 am - 6:00 pmSTL  Lambert-St Louis-SCL Santiago Arturo Merino Benitez
27h 09m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
7:05 pm - 6:01 pmSCL  Santiago Arturo Merino Benitez-STL Lambert-St Louis
25h 56m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,015LATAM Airlines
Booking Insights

Price, demand and travel trends for St. Louis to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from St. Louis to Santiago with more confidence.

What's the cheapest day of the week to fly from St. Louis to Santiago?

Wednesday is the cheapest day of the week to fly from St. Louis to Santiago, it is 23% cheaper than the average day. Sunday is the most expensive day with flight prices 33% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from St. Louis to Santiago?

•July is the cheapest month to fly from St. Louis to Santiago at $811 round-trip.
•June ($1,605) and October ($1,603) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 97% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for St. Louis to Santiago flights

Low season

October

Cheapest flight

$564
Best time to beat the crowds but there is an average 47% increase in price.
Most popular time to fly with an average 7% increase in price.
Flight from St. Louis to Santiago

When to book flights from St. Louis to Santiago

Are your dates flexible? Find out the best times to travel from St. Louis to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Santiago flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from St. Louis to Santiago?

    Flights from St. Louis to Santiago usually depart from Lambert-St Louis (STL) and arrive at Santiago Arturo Merino Benitez (SCL).

  • What cabin classes can I book on flights from St. Louis to Santiago?

    Three cabin classes are available on flights from St. Louis to Santiago:

    • Economy Class
    • Premium Economy Class
    • First Class

  • Which airports do connecting flights from St. Louis to Santiago pass through?

    One-stop flights from St. Louis to Santiago most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 63% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 13% of one-stop connections
    • Miami (MIA) - 13% of one-stop connections
    • Dallas/Fort Worth (DFW) - 10% of one-stop connections

    Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from St. Louis to Santiago?

    Yes. Being flexible with your travel dates can save you up to 43% on the St. Louis to Santiago route. Wednesday is the cheapest departure day at $843 round-trip on average, while Sunday is the most expensive at $1,456, a difference of $613. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

  • How long is a flight from St. Louis to Santiago?

    A nonstop flight from St. Louis to Santiago takes 0h 00m, covering 5,137 miles.

  • Do I need a passport to fly from St. Louis to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from St. Louis to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $870 to $7,925. That means the highest observed fare was about 9x higher than the lowest one.

  • How are flight prices from St. Louis to Santiago looking right now?

    One-way fares from St. Louis to Santiago are currently higher than usual. Average one-way flight prices are about $688, which is 5% above the typical average for this route.

  • How much time can I save by choosing a different layover airport from St. Louis to Santiago?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 13h 51m, compared with 13h 52m via Dallas/Fort Worth (DFW) and 13h 56m via Houston George Bush Intcntl (IAH).

  • What is the time difference between St. Louis and Santiago?

    Santiago is 2 hours ahead of St. Louis (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:
    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • How much should I expect to pay for a St. Louis to Santiago flight?

    Round-trip flights from St. Louis to Santiago range from $858 to $1,382, with an average of $1,088 over the past 12 months. Anything below $858 counts as a good deal.

Your guide to booking St. Louis to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Sunday. On this route, Wednesday flights average $843 - about $613 less than Sunday (42% savings) based on the last 12 months.
  • If you can choose when to travel, plan your St. Louis to Santiago trip for July. Fares historically average $811 round-trip in that month - typically $794 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.
    - Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from St. Louis to Santiago

Complete your trip to Santiago with a hotel stay or car rental

Car rentals in Santiago
Hotels in Santiago
Vacations in Santiago