STL - SCL

$818 Find Cheap Flights from St. Louis to Santiago

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santiago departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$818
Typical prices: $823-$1,216
LATAM Airlines
Wed 3/11Mon 3/23
STL - SCL • 2 stops
Cheapest one-way
Multiple Airlines
Sun 2/1
STL - SCL • multi-stop
Top airlines
LATAM Airlines
Cheapest • from $818 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
July
Cheapest • 15% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santiago (STL-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santiago

Wed, Mar 11 - Mon, Mar 23
LATAM Airlines Logo
7:03 am - 5:35 am
STL
-
SCL
20h 32m
2 stops
LATAM Airlines Logo
11:25 pm - 5:53 pm
SCL
-
STL
20h 28m
2 stops
$818LATAM Airlines
Wed, Mar 11 - Mon, Mar 23
LATAM Airlines Logo
6:00 am - 5:35 am
STL
-
SCL
21h 35m
2 stops
LATAM Airlines Logo
11:25 pm - 5:53 pm
SCL
-
STL
20h 28m
2 stops
$826LATAM Airlines
Wed, Mar 11 - Mon, Mar 23
United Airlines Logo
4:47 pm - 7:50 am
STL
-
SCL
13h 03m
1 stop
United Airlines Logo
9:45 pm - 9:21 am
SCL
-
STL
13h 36m
1 stop
$858United Airlines
Wed, Mar 11 - Mon, Mar 23
LATAM Airlines Logo
6:00 am - 5:35 am
STL
-
SCL
21h 35m
2 stops
LATAM Airlines Logo
8:15 am - 11:09 am
SCL
-
STL
28h 54m
3 stops
$893LATAM Airlines
Fri, Mar 20 - Mon, Mar 30
Delta Logo
10:12 am - 6:45 am
STL
-
SCL
18h 33m
2 stops
Delta Logo
8:55 pm - 11:09 am
SCL
-
STL
16h 14m
2 stops
$898Delta
Fri, Mar 20 - Mon, Mar 30
LATAM Airlines Logo
4:21 pm - 2:10 pm
STL
-
SCL
19h 49m
3 stops
LATAM Airlines Logo
11:00 pm - 5:53 pm
SCL
-
STL
20h 53m
2 stops
$899LATAM Airlines
Mon, Mar 9 - Fri, Mar 20
American Airlines Logo
1:34 pm - 9:05 am
STL
-
SCL
17h 31m
2 stops
American Airlines Logo
10:15 pm - 10:59 am
SCL
-
STL
14h 44m
1 stop
$903American Airlines
Fri, Apr 10 - Sat, Apr 18
LATAM Airlines Logo
6:59 pm - 1:05 pm
STL
-
SCL
17h 06m
2 stops
LATAM Airlines Logo
7:45 am - 11:34 pm
SCL
-
STL
16h 49m
2 stops
$938LATAM Airlines
Sat, Feb 28 - Sat, Mar 7
United Airlines Logo
4:28 pm - 8:50 am
STL
-
SCL
13h 22m
1 stop
United Airlines Logo
9:45 pm - 8:42 pm
SCL
-
STL
25h 57m
2 stops
$943United Airlines
Sat, Feb 28 - Sat, Mar 7
United Airlines Logo
7:41 am - 8:50 am
STL
-
SCL
22h 09m
2 stops
United Airlines Logo
9:45 pm - 8:07 pm
SCL
-
STL
25h 22m
2 stops
$1,001United Airlines
Booking Insights

KAYAK's insights & trends for St. Louis to Santiago flights

Get data-powered insights and trends into flights from St. Louis to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from St. Louis to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from St. Louis to Santiago departing in March.

What is the cheapest month to fly from St. Louis to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Santiago is July, where tickets cost $883 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $1,647 and $1,183 respectively.

Good to know

Low seasonApril
Cheapest flight$818
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from St. Louis to Santiago

When to book flights from St. Louis to Santiago

Are your dates flexible? Find out the best times to travel from St. Louis to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santiago

  • What is the cheapest flight from St. Louis to Santiago?

    In the last 3 days, the lowest price for a flight from St. Louis to Santiago was $818 for a round-trip ticket.

  • Do I need a passport to fly between St. Louis and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santiago.

  • Which aircraft models fly most regularly from St. Louis to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santiago?

    oneworld, and SkyTeam are the airline alliances operating flights between St. Louis and Santiago, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from St. Louis to Santiago are Delta and LATAM Airlines. With an average price for the route of $1,008 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $913 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from St. Louis to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from St. Louis to Santiago

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8130 reviews
7.9Comfort
7.2Food
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

2.0 MediocreTodd, Jan 2026
IAH - ATL
Read more Delta reviews

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The flight was comfortable and uneventful, which is what I desire

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Update to handle the delay was very bad, crews no smiles or welcome or thanks. Don’t care attitude

It would be nice to have some low carb options in the snacks.

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

Everything you need to know for your flight from St. Louis to Santiago

Information on your arrival and departure airports