SCL - SFO

$278 Find Cheap Flights from Santiago to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to San Francisco.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to San Francisco.
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Everything you should know

Cheapest round-trip
$522
Overall average: $714
LATAM Airlines
Mon 4/27Sun 5/3
SCL - SFO • 3 stops
Cheapest one-way
$278
Typical prices: $448-$495
Avianca
Thu 2/26
SCL - SFO • 2 stops
Top airlines
LATAM Airlines
Cheapest • from $522 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 27% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 14% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to San Francisco (SCL-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to San Francisco

Mon, Apr 27 - Sun, May 3
LATAM Airlines Logo
8:30 am - 3:21 pm
SCL
-
SFO
33h 51m
3 stops
LATAM Airlines Logo
6:00 am - 7:15 am
SFO
-
SCL
22h 15m
2 stops
$522LATAM Airlines
Sun, May 17 - Sun, Jun 14
LATAM Airlines Logo
10:30 am - 1:36 pm
SCL
-
SFO
30h 06m
2 stops
LATAM Airlines Logo
7:00 am - 5:35 am
SFO
-
SCL
19h 35m
1 stop
$523LATAM Airlines
Tue, Apr 21 - Mon, May 4
Avianca Logo
6:40 am - 11:55 pm
SCL
-
SFO
20h 15m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$527Avianca
Wed, Apr 1 - Thu, Apr 23
LATAM Airlines Logo
8:40 pm - 7:19 pm
SCL
-
SFO
26h 39m
1 stop
LATAM Airlines Logo
11:39 pm - 1:35 pm
SFO
-
SCL
34h 56m
2 stops
$535LATAM Airlines
Wed, Apr 1 - Thu, Apr 30
LATAM Airlines Logo
5:30 pm - 7:19 pm
SCL
-
SFO
29h 49m
2 stops
LATAM Airlines Logo
10:55 pm - 6:50 am
SFO
-
SCL
28h 55m
1 stop
$538LATAM Airlines
Wed, Apr 22 - Mon, Apr 27
LATAM Airlines Logo
11:05 pm - 7:09 pm
SCL
-
SFO
23h 04m
2 stops
LATAM Airlines Logo
8:00 am - 2:05 pm
SFO
-
SCL
27h 05m
2 stops
$539LATAM Airlines
Sun, May 3 - Wed, May 27
LATAM Airlines Logo
8:40 pm - 3:21 pm
SCL
-
SFO
21h 41m
2 stops
LATAM Airlines Logo
9:30 am - 7:15 am
SFO
-
SCL
18h 45m
2 stops
$540LATAM Airlines
Thu, May 28 - Thu, Aug 20
Avianca Logo
6:40 am - 11:55 pm
SCL
-
SFO
20h 15m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$542Avianca
Mon, Apr 6 - Mon, Apr 13
LATAM Airlines Logo
11:00 pm - 7:19 pm
SCL
-
SFO
23h 19m
2 stops
LATAM Airlines Logo
12:06 pm - 7:15 am
SFO
-
SCL
16h 09m
1 stop
$544LATAM Airlines
Wed, Apr 15 - Wed, May 6
American Airlines Logo
8:35 pm - 8:54 pm
SCL
-
SFO
27h 19m
1 stop
American Airlines Logo
6:15 am - 7:05 am
SFO
-
SCL
21h 50m
1 stop
$547American Airlines
Booking Insights

KAYAK's insights & trends for Santiago to San Francisco flights

Get data-powered insights and trends into flights from Santiago to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santiago to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to San Francisco is October, where tickets cost $554 (return) on average. On the other hand, the most expensive months are June and April, where the average cost of round-trip tickets is $776 and $714 respectively.

How far in advance should I book a flight from Santiago to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to San Francisco, you should book around 4 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$278
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 21% increase in price.
Flight from Santiago to San Francisco

When to book flights from Santiago to San Francisco

Are your dates flexible? Find out the best times to travel from Santiago to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to San Francisco

  • What is the cheapest flight from Santiago to San Francisco?

    In the last 3 days, the lowest price for a flight from Santiago to San Francisco was $278 for a one-way ticket and $522 for a round-trip.

  • Do I need a passport to fly between Santiago and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Santiago to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to San Francisco?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Santiago and San Francisco, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Santiago to San Francisco, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to San Francisco are Delta and LATAM Airlines. With an average price for the route of $747 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $701 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Santiago to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santiago with another airline. Booking your flights between Santiago and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Santiago to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santiago to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8180 reviews
7.8Entertainment
8.5Crew
7.9Comfort
7.2Food
8.1Boarding
Airline reviews

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

2.0 MediocreJaspreet, Feb 2026
SEA - SMF
Read more Delta reviews

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

I've flown several other airlines, and Delta is really on top on things.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

The crew was not very visible. This might be a good thing for people who wanted to sleep but seemed odd when compared to the Atlantic crossing where they are more present in the cabin. The Food (beef) was not good. Tough and tasteless. Would love to see more choices on a long flight like that.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Some of the Air hostesses are not that friendly. Need improvement

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

did not have enough meal for first class passengers so offer us snack

We were upgraded to Business Class. So comfortable with great service and food options

The flight was completely full. Crew was not happy. Everyone was rude and brusque. Travelling with an arm in a cast and seating in the first row of economy cabin (in front of the separation) I needed help retrieving my tray for the meal. A staff member literally threw the tray on my lap, without helping to take out the tray. Boarding was messy, with 300 people waiting in an encloses space with low ceiling. I will try to avoid AA next time I have a long flight.

The comfort of Business Class made this trip far more comfortable. I was indeed surprised when I asked one of the flight attendant to help me set up my "bed", she responded that "We don't make beds in Business Class any longer...only First Class" I believe her name was Giselle, but I'm not certain. She did instruct me how to adjust the seat, place the hooded cover and I clearly understood how to place the blanket and the cover. Additionally, the meal I was served (a beef dish) was almost inedible. The beef was tough and odd tasting. I didn't mention it as I was hoping to quickly settle down and try to get some sleep.

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

Everything you need to know for your flight from Santiago to San Francisco

Information on your arrival and departure airports