$309 Find Cheap Flights from Santiago to San Francisco - Compare and Save

In the last 5 days, the lowest price for a flight from Santiago to San Francisco was $309 for a one-way ticket and $603 for a round-trip.

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We unfortunately don’t have that data for this specific route.

SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Santiago and San Francisco, with SkyTeam being the most commonly used for this route.

The two airlines most popular with KAYAK users for flights from Santiago to San Francisco are Delta and Copa Airlines. With an average price for the route of $735 and an overall rating of 7.8, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $757 and an overall rating of 7.6.

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to San Francisco.

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santiago with another airline. Booking your flights between Santiago and SFO can sometimes prove cheaper using this method.

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.