SCL - SFO

$437 Find Cheap Flights from Santiago to San Francisco - Compare and Save

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Everything you should know

Cheapest round-trip
$818
Typical prices: $598-$877
Avianca
Mon 2/5Mon 3/5
SCL - SFO • 2 stops
Cheapest one-way
$437
Typical prices: $396-$680
Multiple Airlines
Fri 12/7
SCL - SFO • 2 stops
Nonstop flights
There are currently no direct flights between Santiago and San Francisco. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 13 weeks in advance save around 42% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 15% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $720 (round-trip)
Shortest trip • 15h 26m (one-way)
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Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to San Francisco (SCL-SFO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to San Francisco

Fri, Feb 5 - Fri, Mar 5
Avianca Logo
7:30 am - 9:40 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:00 pm - 1:05 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 05m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$818Avianca
Wed, Mar 31 - Fri, Apr 9
Avianca Logo
6:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
2:15 pm - 2:15 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 00m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$819Avianca
Tue, Feb 2 - Wed, Feb 17
LATAM Airlines Logo
7:40 am - 9:21 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 41m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
8:00 am - 7:40 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
18h 40m1 stop Atlanta Hartsfield-Jackson
$835LATAM Airlines
Tue, Feb 2 - Wed, Feb 17
LATAM Airlines Logo
11:10 pm - 10:44 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 34m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:00 am - 7:40 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 40m1 stop Atlanta Hartsfield-Jackson
$855LATAM Airlines
Wed, Apr 28 - Sun, May 9
Copa Airlines Logo
10:58 pm - 11:40 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
27h 42m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:55 pm - 2:41 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 46m1 stop Panama City Tocumen Intl
$883Copa Airlines
Tue, Jan 19 - Fri, Apr 16
Copa Airlines Logo
3:53 am - 5:25 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 32m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:55 pm - 1:52 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
14h 57m1 stop Panama City Tocumen Intl
$911Copa Airlines
Tue, Feb 2 - Tue, Feb 16
Delta Logo
8:25 pm - 11:02 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 37m2 stops Lima J Chavez Intl Los Angeles
Delta Logo
11:53 am - 7:40 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
14h 47m1 stop Atlanta Hartsfield-Jackson
$930Delta
Sat, Jan 30 - Mon, Feb 15
Delta Logo
9:50 pm - 12:42 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 52m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:59 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
14h 36m1 stop Los Angeles
$930Delta
Fri, Feb 19 - Fri, Mar 5
United Airlines Logo
10:45 pm - 10:55 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
17h 10m1 stop Houston George Bush Intcntl
United Airlines Logo
12:45 am - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 05m1 stop Houston George Bush Intcntl
$930United Airlines
Thu, Dec 10 - Sun, Mar 7
Air Canada Logo
9:55 pm - 11:10 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 15m1 stop Toronto Pearson Intl
Air Canada Logo
6:30 am - 12:15 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
24h 45m2 stops Vancouver Intl Toronto Pearson Intl
$935Air Canada
Booking Insights

Price, demand and travel trends for Santiago to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santiago to San Francisco?

Round-trip flights from Santiago to San Francisco typically range from $598 to $877. The lowest price found in the past 5 days was $818, on Avianca.

What's the cheapest day of the week to fly from Santiago to San Francisco?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santiago to San Francisco. It’s 10% cheaper than the average day, while Saturday is the most expensive, with prices 16% higher.

What’s the cheapest month to fly from Santiago to San Francisco?

•February is the cheapest month to fly from Santiago to San Francisco at $603 round-trip.
•October ($945) and November ($881) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 56% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Santiago to San Francisco the cheapest?

Flights from Santiago to San Francisco are cheapest 13 weeks before departure. Booking in this window typically costs about 42% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for Santiago to San Francisco flights

Low season

October

Cheapest flight

$437
Beat the crowds with an average 39% drop in travelers.
The most popular month to fly with an average 27% increase in travelers.
One-way flight from Santiago to San Francisco

When to book flights from Santiago to San Francisco

Are your dates flexible? Find out the best times to travel from Santiago to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santiago to San Francisco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santiago to San Francisco?

    Three cabin classes are available on flights from Santiago to San Francisco:

    • Economy Class
    • Business Class
    • First Class

  • How long is a flight from Santiago to San Francisco?

    A nonstop flight from Santiago to San Francisco takes 00m, covering 5,918 miles.

  • Do I need a passport to fly from Santiago to San Francisco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santiago to San Francisco flight?

    Round-trip flights from Santiago to San Francisco range from $598 to $877, with an average of $712 over the past 12 months. Anything below $598 counts as a good deal.

  • How expensive are last-minute Santiago to San Francisco flights?

    Last-minute fares on this route (booked within two weeks of departure) run 44% above the $712 route average. Book 13 weeks before departure for the lowest fares.

  • Have flight prices from Santiago to San Francisco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $818 to $7,773. That means the highest observed fare was about 10x higher than the lowest one.

  • How are flight prices from Santiago to San Francisco looking right now?

    One-way fares from Santiago to San Francisco are currently higher than usual. Average one-way flight prices are about $621, which is 16% above the typical average for this route.

  • What car rental options are available at San Francisco Airport (SFO)?

    San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include:

    • Europcar
    • Thrifty
    • Dollar
    • Hertz
    • Fox

  • Which airports can I use when flying from Santiago to San Francisco?

    Flights from Santiago to San Francisco usually depart from Santiago Arturo Merino Benitez (SCL) and arrive at San Francisco (SFO).

  • Which airports do connecting flights from Santiago to San Francisco pass through?

    One-stop flights from Santiago to San Francisco most commonly connect through:

    • Los Angeles (LAX) - 36% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 24% of one-stop connections
    • Miami (MIA) - 14% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 10% of one-stop connections

  • Can I save money by using flexible dates for flights from Santiago to San Francisco?

    Yes. Flexible dates can save you up to 23% on flights from Santiago to San Francisco. Wednesday is the cheapest departure day at $643 round-trip on average, while Saturday is the most expensive at $832, a difference of $189.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santiago to San Francisco?

    Flying via Los Angeles (LAX) gives the shortest average 1-stop total travel time at 15h 26m, compared with 16h 50m via Mexico City Benito Juarez (MEX) and 16h 51m via Panama City Tocumen Intl (PTY).

  • What is the time difference between Santiago and San Francisco?

    San Francisco is 5 hours behind Santiago (Pacific Time vs Chile Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Francisco?

    Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Your guide to booking Santiago to San Francisco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Saturday. On this route, Wednesday flights average $643, about $189 less than Saturday fares (23% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 42% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santiago to San Francisco trip for February. Fares historically average $603 round-trip in that month - typically $342 less than the most expensive month, which is October (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

    • Grand Hyatt At Sfo

More options for your flight from Santiago to San Francisco

Complete your trip to San Francisco with a hotel stay or car rental