SCL - SFO

$397 Find Cheap Flights from Santiago to San Francisco - Compare and Save

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Everything you should know

Cheapest round-trip
$764
Typical prices: $564-$797
Avianca
Mon 11/12Thu 1/18
SCL - SFO • 2 stops
Cheapest one-way
$397
Typical prices: $411-$642
Multiple Airlines
Sun 10/28
SCL - SFO • 2 stops
Nonstop flights
There are currently no direct flights between Santiago and San Francisco. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 12 weeks in advance save around 32% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 13% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $672 (round-trip)
Shortest trip • 15h 28m (one-way)
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Insights
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We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to San Francisco (SCL-SFO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to San Francisco

Thu, Dec 3 - Sat, Jan 9
Avianca Logo
7:30 am - 9:40 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
1:15 pm - 3:10 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 55m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$764Avianca
Thu, Nov 12 - Mon, Jan 18
Avianca Logo
7:30 am - 9:40 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
1:15 pm - 3:10 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 55m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$764Avianca
Thu, Feb 18 - Thu, Mar 4
LATAM Airlines Logo
11:55 pm - 11:04 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 09m1 stop Los Angeles
LATAM Airlines Logo
7:00 am - 5:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 20m2 stops Los Angeles Lima J Chavez Intl
$783LATAM Airlines
Thu, Feb 18 - Thu, Mar 4
LATAM Airlines Logo
9:55 pm - 11:04 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 09m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
7:00 am - 5:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 20m2 stops Los Angeles Lima J Chavez Intl
$783LATAM Airlines
Wed, Feb 10 - Wed, Feb 17
Delta Logo
11:10 pm - 10:32 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:15 pm - 6:00 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 45m2 stops Los Angeles Lima J Chavez Intl
$795Delta
Wed, Feb 10 - Wed, Feb 17
Delta Logo
11:10 pm - 10:32 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 7:40 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 40m1 stop Atlanta Hartsfield-Jackson
$795Delta
Mon, Dec 21 - Mon, Jan 4
United Airlines Logo
10:45 pm - 12:58 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
31h 13m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 am - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
22h 50m1 stop Houston George Bush Intcntl
$823United Airlines
Mon, Dec 21 - Tue, Dec 29
United Airlines Logo
10:45 pm - 12:58 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
31h 13m1 stop Houston George Bush Intcntl
United Airlines Logo
11:59 pm - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 51m1 stop Houston George Bush Intcntl
$829United Airlines
Sun, Feb 28 - Mon, Mar 22
Copa Airlines Logo
3:58 am - 11:15 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
24h 17m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:55 pm - 3:41 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 46m1 stop Panama City Tocumen Intl
$832Copa Airlines
Thu, Dec 3 - Sat, Dec 12
Copa Airlines Logo
12:20 pm - 11:17 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
15h 57m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:36 pm - 8:11 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 35m1 stop Panama City Tocumen Intl
$833Copa Airlines
Booking Insights

Price, demand and travel trends for Santiago to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santiago to San Francisco?

Round-trip flights from Santiago to San Francisco typically range from $564 to $797. The lowest price found in the past 5 days was $764, on Avianca.

What's the cheapest day of the week to fly from Santiago to San Francisco?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santiago to San Francisco. It’s 8% cheaper than the average day, while Sunday is the most expensive, with prices 10% higher.

What’s the cheapest month to fly from Santiago to San Francisco?

•November is the cheapest month to fly from Santiago to San Francisco at $575 round-trip.
•June ($788) and January ($721) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 37% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Santiago to San Francisco the cheapest?

Flights from Santiago to San Francisco are cheapest 12 weeks before departure. Booking in this window typically costs about 32% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for Santiago to San Francisco flights

Low season

October

Cheapest flight

$397
Beat the crowds with an average 31% drop in travelers.
The most popular month to fly with an average 19% increase in travelers.
One-way flight from Santiago to San Francisco

When to book flights from Santiago to San Francisco

Are your dates flexible? Find out the best times to travel from Santiago to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santiago to San Francisco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santiago to San Francisco?

    Three cabin classes are available on flights from Santiago to San Francisco:

    • Economy Class
    • Business Class
    • First Class

  • How long is a flight from Santiago to San Francisco?

    A nonstop flight from Santiago to San Francisco takes 00m, covering 5,918 miles.

  • Do I need a passport to fly from Santiago to San Francisco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santiago to San Francisco flight?

    Round-trip flights from Santiago to San Francisco range from $564 to $797, with an average of $663 over the past 12 months. Anything below $564 counts as a good deal.

  • How expensive are last-minute Santiago to San Francisco flights?

    Last-minute fares on this route (booked within two weeks of departure) run 32% above the $663 route average. Book 12 weeks before departure for the lowest fares.

  • Have flight prices from Santiago to San Francisco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $764 to $7,266. That means the highest observed fare was about 10x higher than the lowest one.

  • How are flight prices from Santiago to San Francisco looking right now?

    One-way fares from Santiago to San Francisco are currently higher than usual. Average one-way flight prices are about $551, which is 6% above the typical average for this route.

  • What car rental options are available at San Francisco Airport (SFO)?

    San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates starting from around $15 for economy cars. Top options include:

    • Thrifty
    • Europcar
    • Dollar
    • Hertz
    • Fox

  • Which airports can I use when flying from Santiago to San Francisco?

    Flights from Santiago to San Francisco usually depart from Santiago Arturo Merino Benitez (SCL) and arrive at San Francisco (SFO).

  • Which airports do connecting flights from Santiago to San Francisco pass through?

    One-stop flights from Santiago to San Francisco most commonly connect through:

    • Los Angeles (LAX) - 32% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 21% of one-stop connections
    • Miami (MIA) - 14% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 13% of one-stop connections

  • Can I save money by using flexible dates for flights from Santiago to San Francisco?

    Yes. Flexible dates can save you up to 17% on flights from Santiago to San Francisco. Wednesday is the cheapest departure day at $614 round-trip on average, while Sunday is the most expensive at $735, a difference of $121.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santiago to San Francisco?

    Flying via Los Angeles (LAX) gives the shortest average 1-stop total travel time at 15h 28m, compared with 16h 50m via Mexico City Benito Juarez (MEX) and 16h 51m via Panama City Tocumen Intl (PTY).

  • What is the time difference between Santiago and San Francisco?

    San Francisco is 4 hours behind Santiago (Pacific Time vs Chile Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Francisco?

    Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Your guide to booking Santiago to San Francisco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Sunday. On this route, Wednesday flights average $614, about $121 less than Sunday fares (16% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 12 weeks before you fly. On this route, that window historically saves about 32% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santiago to San Francisco trip for November. Fares historically average $575 round-trip in that month - typically $213 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

    • Grand Hyatt At Sfo

More options for your flight from Santiago to San Francisco

Complete your trip to San Francisco with a hotel stay or car rental