$439 Find Cheap Flights from South America to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from South America to Panama City

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Panama City

Thu, Mar 26 - Mon, Mar 30
Delta Logo
10:55 am - 10:42 pmBOG-ECP
11h 47m2 stops
Delta Logo
6:00 am - 6:40 pmECP-BOG
12h 40m2 stops
$562Delta
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Fri, Jan 16 - Tue, Jan 20
Delta Logo
3:55 pm - 8:20 amBOG-ECP
17h 25m1 stop
Delta Logo
6:00 am - 7:30 pmECP-BOG
12h 30m1 stop
$589Delta
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Thu, Mar 26 - Mon, Mar 30
Delta Logo
10:55 am - 10:42 pmBOG-ECP
11h 47m2 stops
Delta Logo
7:45 am - 6:40 pmECP-BOG
10h 55m2 stops
$592Delta
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Wed, Mar 25 - Mon, Mar 30
United Airlines Logo
1:30 am - 11:52 amBOG-ECP
10h 22m1 stop
United Airlines Logo
12:55 pm - 4:54 amECP-BOG
15h 59m1 stop
$596United Airlines
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Fri, Nov 7 - Wed, Nov 12
American Airlines Logo
11:55 pm - 2:50 pmBOG-ECP
15h 55m1 stop
American Airlines Logo
1:11 pm - 11:30 pmECP-BOG
9h 19m1 stop
$618American Airlines
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Fri, Jan 16 - Tue, Jan 20
Delta Logo
10:55 am - 8:20 amBOG-ECP
22h 25m2 stops
Delta Logo
6:00 am - 3:15 amECP-BOG
20h 15m2 stops
$620Delta
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Fri, Nov 7 - Wed, Nov 12
American Airlines Logo
8:00 am - 11:15 pmBOG-ECP
16h 15m2 stops
American Airlines Logo
5:50 pm - 2:15 pmECP-BOG
19h 25m2 stops
$623American Airlines
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Sun, Nov 2 - Sat, Nov 8
United Airlines Logo
1:30 am - 9:49 pmBOG-ECP
21h 19m1 stop
United Airlines Logo
10:04 am - 10:35 pmECP-BOG
11h 31m1 stop
$631United Airlines
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Sat, Nov 1 - Fri, Nov 28
Multiple Airlines Logo
9:45 am - 10:19 amMDE-ECP
24h 34m1 stop
Multiple Airlines Logo
6:30 am - 4:55 pmECP-MDE
33h 25m2 stops
$969Multiple Airlines
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Fri, Nov 14 - Sat, Nov 22
Multiple Airlines Logo
1:30 am - 4:24 pmBOG-ECP
15h 54m1 stop
Multiple Airlines Logo
5:02 pm - 7:30 pmECP-BOG
25h 28m2 stops
$1,072Multiple Airlines
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Everything you should know

Cheapest round-trip
$562
Overall average: $870
Delta
Thu 3/26Mon 3/30
BOG - ECP • 2 stops
Cheapest one-way
$439
American Airlines
Sat 11/1
MDE - ECP • 2 stops
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Useful Info

Good to know

Low seasonOctober
Cheapest flight$439
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Medellín to Panama City

FAQs for booking flights from South America to Panama City

  • How does KAYAK find such low prices on flights from South America to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from South America to Panama City

 
Need help choosing which airline to fly with from South America to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8924 reviews
7.1Entertainment
6.6Food
7.3Comfort
7.7Boarding
8.1Crew
Airline reviews

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

2.0 MediocreAnonymous, Sep 2025ORD - SFO
Read more United Airlines reviews

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

Could have said yes to a glass of wine 🍷 instead of saying we'll come around in a couple of hours

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

Check in was quick and easy during early hours. Flight was on time, and customer services was a plus.

Flight was delayed for 5 hours because crew didn’t have enough time to rest - this seems like it could have been avoided with better scheduling. Food was not good.

I understand that the food on the airplane wouldn’t be fantastic. However, it wasn’t good at all. 😭

Terrible. They wouldn't allow me on my flight on the 14th..

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

IAD with the archaic people movers is just a place to be avoided.

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