$255 Find Cheap Flights from Central America to John Wayne (Santa Ana) - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Santa Ana departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Central America to Santa Ana

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Central America to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Central America to Santa Ana

Wed, Oct 21 - Sun, Oct 25
United Airlines Logo
1:25 pm - 9:51 pm-
9h 26m
United Airlines Logo
7:45 am - 7:32 am-
22h 47m
$522United Airlines
Thu, Oct 22 - Mon, Oct 26
United Airlines Logo
1:25 pm - 1:14 pm-
24h 49m
United Airlines Logo
8:00 pm - 7:39 pm-
22h 39m
$536United Airlines
Thu, Oct 22 - Mon, Oct 26
United Airlines Logo
1:25 pm - 9:29 am-
21h 04m
United Airlines Logo
6:36 pm - 7:32 am-
11h 56m
$536United Airlines
Fri, Oct 9 - Wed, Oct 21
United Airlines Logo
1:25 pm - 12:03 pm-
23h 38m
United Airlines Logo
4:15 pm - 12:21 pm-
19h 06m
$546United Airlines
Fri, Sep 18 - Sat, Oct 3
American Airlines Logo
2:57 pm - 10:50 am-
20h 53m
American Airlines Logo
1:40 pm - 11:59 am-
21h 19m
$559American Airlines
Tue, Oct 6 - Mon, Oct 12
American Airlines Logo
12:05 pm - 9:52 am-
22h 47m
American Airlines Logo
6:37 pm - 1:05 pm-
17h 28m
$565American Airlines
Tue, Oct 6 - Mon, Oct 12
American Airlines Logo
12:05 pm - 8:22 am-
21h 17m
American Airlines Logo
7:31 pm - 1:05 pm-
16h 34m
$569American Airlines
Thu, Jan 21 - Tue, Jan 26
Copa Airlines Logo
1:15 am - 2:02 pm-
14h 47m
Copa Airlines Logo
8:00 am - 6:16 pm-
8h 16m
$604Copa Airlines
Wed, Oct 21 - Mon, Oct 26
Multiple Airlines Logo
1:25 pm - 9:51 pm-
9h 26m
Multiple Airlines Logo
8:00 pm - 7:32 am-
10h 32m
$604Multiple Airlines
Tue, Oct 6 - Tue, Oct 13
Multiple Airlines Logo
1:25 pm - 9:51 pm-
9h 26m
Multiple Airlines Logo
6:36 pm - 7:37 pm-
24h 01m
$608Multiple Airlines
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Good to know

Cheapest flight

$255
Most popular time to fly and prices are also 28% lower on average.
Flight from Guatemala City to John Wayne (Santa Ana)

FAQs for booking flights from Central America to John Wayne (Santa Ana)

  • How does KAYAK find such low prices on flights from Central America to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Central America to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Central America to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Central America to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Central America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Central America to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Central America to Santa Ana

 
Need help choosing which airline to fly with from Central America to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10059 reviews
8.1Crew
7.3Comfort
7.7Boarding
7.1Entertainment
6.6Food
Airline reviews

The entire experience convinced my wife, Cathy, and me that traveling Polaris on United is the only way we’ll fly in the future. From check-in and baggage drop to the end of the 12-hour flight, the customer service was exceptional, with numerous staff members exemplifying the very best in care. On board, Andre, our primary crew chief, was sincerely friendly, a consummate professional, and, along with Freddy, one of his team members, truly among the best of the best. The captain even came through the cabin to chat with passengers—a wonderful personal touch, especially on such a long journey.

10.0 ExcellentPat, Jul 2026
Read more United Airlines reviews

The entire experience convinced my wife, Cathy, and me that traveling Polaris on United is the only way we’ll fly in the future. From check-in and baggage drop to the end of the 12-hour flight, the customer service was exceptional, with numerous staff members exemplifying the very best in care. On board, Andre, our primary crew chief, was sincerely friendly, a consummate professional, and, along with Freddy, one of his team members, truly among the best of the best. The captain even came through the cabin to chat with passengers—a wonderful personal touch, especially on such a long journey.

The SFO lounge closes at 12 midnight. My flight took off at 2AM

Delayed 2 hours while stuck on the aircraft. If the luggage was properly loaded the first time we probably wouldn’t have been delayed at all

Flight be on time would be a good start. Then train your flight attendants to be attentive and friendly. This time they completely forgot my row for the measly snack! United, do better!

Destroyed my suitcase. Tired of talking about it. Cancelling my unite mileage plus account.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

The control panel for the seat back screen did not work at all after takeoff.

The crew was nice but the people going to Orange County are so entitled. Everyone thinks everything is suppose for be perfect for them. Tough crowd.

How they treated my luggage was horrible. And foods are not edible… Flight attendants were not listening my request. Etc

My flight in Dallas had maintenance issues. Which caused us to missed our connecting flight in LA. We had to stay overnight in Los Angeles. American Airlines booked us a hotel. The hotel was the Holiday Inn. It was horrible. The whole hotel smelled like weed and there were people rambling all night long up and down the hallways. The carpets in the hallway and the room has stains. There was dirt on the floor. It was so nasty that I slept in my clothes.

Great. Clean. Seats comfortable. Food was free. Had new release movies.

The airplane I love and I love I came back safe thank you American airlines

Horrible. No AC. No Air inside the plane. We had to deplane twice! It is late almost 5 hrs in total. I almost passed out and about to call 911. I asked the crew to be honest and open the door. The lady next to me was lay down in the floor due to heat and no air inside the plane. I got headaches, can’t wait the replacement flight about midnight Dallas time. I end it up rebook for next day flight and stay overnight using my own pocket in a hotel nearby due to headaches and can’t breath. I still have a headache this morning. Still not decided yes how to file this issue to AA and/or FAA.

Service could be better especially in business class.. the food also needs to be better and the overall experience should be elevated.

Worst communication. Delayed boarding for two hours without a single announcement until hour 1 had passed - on time status showing until our flight was supposed to takeoff and the crew had already walked away. No one was boarding. Disgusting part of DFW overcrowded with no AC on a 97 degree day. Then the first app update is that we’d take off in 15 mins… but again no one had boarded a full flight. No announcement in the terminal so everyone is just crowded around a disgusting place with no info for over an hour which turned into two. This was an overfill flight and a disgrace to passenger decency all while likely just trying to fix their own issue of overbooking. The worst airline at the worst airport.

To have arrived on time and not 3 hours late after having already spent $100 to change to an earlier flight, only to arrive back home close to the original flight time.

The WiFi would not connect enough for me to do my actual work. It permaspooled, disconnected, said it was connected, then wouldn't open an email... it was frustrating. I am not a tall person, 5'4" - and I felt cramped with little room to reach into my bag under the seat in front of me. I feel sorry for anyone taller than me having to fly. the one positive thing I will add, is the overhead bins are roomy enough to manage more bags than other carriers.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

On our return trip we were able to get on an earlier flight. American airlines made it so easy to do & at no cost!

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