$288 Find Cheap Flights from Central America to John Wayne (Santa Ana)

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Santa Ana departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Central America to Santa Ana

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Central America to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Central America to Santa Ana

Thu, Oct 22 - Tue, Oct 27
Multiple Airlines Logo
5:25 am - 5:10 pm
GUA
-
SNA
12h 45m
2 stops
Multiple Airlines Logo
8:31 pm - 9:00 am
SNA
-
GUA
11h 29m
2 stops
$464Multiple Airlines
Tue, Nov 17 - Wed, Nov 25
Multiple Airlines Logo
5:25 am - 2:02 pm
GUA
-
SNA
10h 37m
2 stops
Multiple Airlines Logo
7:59 pm - 9:00 am
SNA
-
GUA
11h 01m
2 stops
$473Multiple Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
2:23 pm - 9:42 am
GUA
-
SNA
20h 19m
2 stops
American Airlines Logo
4:55 pm - 1:22 pm
SNA
-
GUA
19h 27m
2 stops
$532American Airlines
Wed, Sep 23 - Sun, Sep 27
United Airlines Logo
12:27 pm - 9:24 am
GUA
-
SNA
21h 57m
2 stops
United Airlines Logo
6:30 pm - 6:49 pm
SNA
-
GUA
23h 19m
2 stops
$541United Airlines
Tue, Sep 15 - Sat, Sep 26
American Airlines Logo
2:57 pm - 10:36 am
SJO
-
SNA
20h 39m
2 stops
American Airlines Logo
4:35 pm - 11:59 am
SNA
-
SJO
18h 24m
2 stops
$545American Airlines
Wed, Aug 12 - Sat, Aug 15
Frontier Logo
2:47 pm - 1:42 pm
GUA
-
SNA
23h 55m
2 stops
Frontier Logo
7:53 pm - 10:05 am
SNA
-
GUA
13h 12m
2 stops
$563Frontier
Sun, Oct 25 - Mon, Nov 2
United Airlines Logo
1:10 am - 9:53 pm
GUA
-
SNA
21h 43m
1 stop
United Airlines Logo
7:00 pm - 7:39 pm
SNA
-
GUA
22h 39m
2 stops
$573United Airlines
Tue, Sep 29 - Sun, Oct 11
Azul Logo
1:25 pm - 9:51 pm
SJO
-
SNA
9h 26m
1 stop
Azul Logo
7:45 am - 7:15 am
SNA
-
SJO
22h 30m
1 stop
$597Azul
Tue, Nov 10 - Sun, Nov 15
Azul Logo
7:15 am - 2:02 pm
SAP
-
SNA
8h 47m
1 stop
Azul Logo
12:10 pm - 10:57 pm
SNA
-
SAP
8h 47m
1 stop
$880Azul
Thu, Aug 13 - Mon, Aug 24
Frontier Logo
9:30 am - 8:05 am
SAP
-
SNA
23h 35m
2 stops
Frontier Logo
8:10 pm - 8:25 am
SNA
-
SAP
11h 15m
2 stops
$895Frontier
Useful Info

Good to know

Low seasonOctober
Cheapest flight$288
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 15% lower on average.
Flight from Guatemala City to John Wayne (Santa Ana)

FAQs for booking flights from Central America to John Wayne (Santa Ana)

  • How does KAYAK find such low prices on flights from Central America to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Central America to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Central America to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Central America to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Central America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Central America to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Central America to Santa Ana

 
Need help choosing which airline to fly with from Central America to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9775 reviews
6.6Food
7.3Comfort
7.7Boarding
8.1Crew
7.1Entertainment
Airline reviews

New plane was lovely. Crew customer service is always lax but expected. Kraft on time and arrived safely.

10.0 ExcellentKaryn, Jun 2026
DEN - LAX
Read more United Airlines reviews

New plane was lovely. Crew customer service is always lax but expected. Kraft on time and arrived safely.

Uncomfortable plastic seats even in premium economy. No free wifi. Even paid wifi was spotty to nonexistent. Bad food. Much worse than economy on foreign carriers like Qantas.

How can you rate a flight when it is canceled after you leave the gate & 3 hours into sitting there or in remote area of airport after mechanical problems

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

First class ticket gets you no seat back entertainment? I have to bring my own laptop to see a movie? And most of their movies have ADS? No thank you. Worse: Tiny snacks only on a 2 hr flight?

Late plane. Only one crew on the ground so we b had to wait for Denver flight to come in, board, and depart. At 78 yrs of age I was not pleased trying to get my connection. What really made me angry was the notification you sent me to hurry up or I would miss my connection. Why tell me to hurry up when you got me in late. It was not a good way of treating customers.

No complaints other than luggage carousel was incorrectly guiding passengers to the wrong carousel on the screen.

Seats were not super comfortable and food was not good at all. If I had a chance I would definitely fly a different airline. Of course they are better than any budget airline, but not by much.

Flew steerage class. Short on leg room unless you pay more. No window unless you pay more. Etc. United is trying to squeeze every cent from you. It doesn’t make for any loyalty.

This was my first flight on Aer Lingus and it was great. The plane wasn't full so I could move to a seat with extra room. The food was pretty good for airline food and the staff was nice and attentive. I enjoyed the media provided during my 10 hour flight. We arrived home early and it's always good to be home!

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

The seat when "flat" was not flat and pad was too thin to cover it.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

To have arrived on time and not 3 hours late after having already spent $100 to change to an earlier flight, only to arrive back home close to the original flight time.

American Airlines is a miserable experience. It is predictably miserable, in the sense that every time I fly American, I brace myself for the certainty that it will be unpleasant and uncomfortable. But it is unpredictable in the sense that I never know if the flight will be on time or delayed nine hours (both happened to me this week). I never know if I will be able to sit in the seat that I selected when I purchased the ticket or if I will be told by Customer Service (!!!) that I must relocate from first class to a seat in the back of the aircraft with no explanation (both happened to me this week). Will the food be frozen and half defrosted, or scalding hot? Will the drinks be warm? Will the flight attendants be surly and mean? Will the toilets be cramped and foul? Will the seats be narrow and uncomfortable? Will there be a real electric outlet at the seat, or just an unreliable USB-2 port? Will there be enough seats in the boarding lounge or just a few? Will the boarding process be smooth and efficient, or will the gate agents mess it up and delay it needlessly for 30 or 40 minutes? Will the catering and cleaning crew be prompt or will they take an extra 30 minutes? Will the brakes on the aircraft work properly, or will the pilot delay takeoff for four hours while the ground crew attends to what can only be described as routine maintenance that should have been done the night before? I've eexperienced every one of these unpleasant things this year, 2026. The only thing I can reliably count on is that American will find a new way to make the experience of flying as miserable as they possibly can.

Wifi was spotty. Tray table was very dirty when I sat down.

The WiFi would not connect enough for me to do my actual work. It permaspooled, disconnected, said it was connected, then wouldn't open an email... it was frustrating. I am not a tall person, 5'4" - and I felt cramped with little room to reach into my bag under the seat in front of me. I feel sorry for anyone taller than me having to fly. the one positive thing I will add, is the overhead bins are roomy enough to manage more bags than other carriers.

Buying ticket from kayak instant booking was a huge mistake, never to be repeated again! The Kayak didn’t book the tickets directly, it handed it off to a third party Underpricer, that booked a code shared American Airlines flight operated by Cathay Pacific!! When managing the booking American Airlines would recognize the itinerary but wouldn’t let me do anything stating, the flight is operated by Cathay Pacific so go to their website. Cathay Pacific would recognize the itinerary, neither by reservation ID or ticket number…asking to reach out to the third party Underpricer….calling Underpricer resulted in no help like seat requests, mileage number or upgrade request, 15hr layover accommodation voucher guidance…so net in net avoid booking through three layers of intermediaries

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