$131 Find Cheap Flights from Santa Ana to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Central America departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$388
San José
San José2 stops$463
Guatemala City
Guatemala City2 stops$407
Panama City
Panama City3 stops$626
Liberia
Liberia2 stops$548
Managua
Managua2 stops$426
San Pedro Sula
San Pedro Sula3 stops$554
Coxen Hole
Coxen Hole2 stops$733
San Salvador
San Salvador2 stops$388
San José
San José2 stops$463
Guatemala City
Guatemala City2 stops$407
Panama City
Panama City3 stops$626
Liberia
Liberia2 stops$548
Managua
Managua2 stops$426
San Pedro Sula
San Pedro Sula3 stops$554
Coxen Hole
Coxen Hole2 stops$733

Book Cheap Santa Ana to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Central America

Sun, Apr 5 - Sun, Apr 12
Frontier Logo
7:27 pm - 5:30 pm
SNA
-
SAL
21h 03m
2 stops
Frontier Logo
11:50 pm - 7:40 pm
SAL
-
SNA
20h 50m
2 stops
$388Frontier
Thu, Apr 16 - Fri, May 1
Spirit Airlines Logo
1:23 pm - 11:20 am
SNA
-
GUA
20h 57m
2 stops
Spirit Airlines Logo
12:15 pm - 8:56 pm
GUA
-
SNA
33h 41m
3 stops
$407Spirit Airlines
Tue, Mar 24 - Sat, Apr 11
Spirit Airlines Logo
2:53 pm - 11:24 am
SNA
-
GUA
19h 31m
2 stops
Spirit Airlines Logo
12:23 pm - 9:53 am
GUA
-
SNA
22h 30m
2 stops
$415Spirit Airlines
Fri, Apr 17 - Mon, Apr 20
Multiple Airlines Logo
4:37 pm - 4:43 pm
SNA
-
SAL
23h 06m
2 stops
Multiple Airlines Logo
10:20 pm - 8:56 pm
SAL
-
SNA
23h 36m
3 stops
$424Multiple Airlines
Wed, Apr 15 - Sat, May 2
Multiple Airlines Logo
4:37 pm - 11:20 am
SNA
-
GUA
17h 43m
2 stops
Multiple Airlines Logo
7:53 am - 8:56 pm
GUA
-
SNA
14h 03m
2 stops
$424Multiple Airlines
Wed, Apr 8 - Wed, Apr 15
Southwest Logo
7:40 pm - 12:30 pm
SNA
-
BZE
15h 50m
2 stops
Southwest Logo
1:25 pm - 9:45 pm
BZE
-
SNA
9h 20m
2 stops
$518Southwest
Wed, Apr 8 - Wed, Apr 15
American Airlines Logo
2:42 pm - 2:30 pm
SNA
-
BZE
22h 48m
1 stop
American Airlines Logo
12:14 pm - 8:50 pm
BZE
-
SNA
9h 36m
1 stop
$525American Airlines
Mon, Apr 6 - Mon, Apr 13
United Airlines Logo
6:28 pm - 11:15 am
SNA
-
BZE
15h 47m
2 stops
United Airlines Logo
12:20 pm - 9:44 am
BZE
-
SNA
22h 24m
2 stops
$571United Airlines
Wed, Apr 15 - Wed, Apr 22
United Airlines Logo
6:39 pm - 12:10 pm
SNA
-
LIR
16h 31m
2 stops
United Airlines Logo
11:49 am - 8:47 pm
LIR
-
SNA
9h 58m
1 stop
$582United Airlines
Wed, Apr 1 - Sat, Apr 4
American Airlines Logo
7:48 pm - 12:50 pm
SNA
-
BZE
16h 02m
2 stops
American Airlines Logo
3:27 pm - 11:36 am
BZE
-
SNA
21h 09m
2 stops
$584American Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Central America flights

Get data-powered insights and trends into flights from Santa Ana to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Ana to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to Central America were found on Spirit Airlines ($407) and Alaska Airlines ($558).

Good to know

Low seasonOctober
Cheapest flight$131
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from John Wayne (Santa Ana) to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Central America

 
Need help choosing which airline to fly with from Santa Ana to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9335 reviews
6.6Food
8.1Crew
7.7Boarding
7.1Entertainment
7.3Comfort
Airline reviews

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

8.0 ExcellentMaureen, Feb 2026
SMF - DEN
Read more United Airlines reviews

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

it was a very short flight so my expectations were low.

Entertainment kept turning itself off. Gave up on watching a movie.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Terrible. Our first time back on United for 10 years, the seats in Polaris class are small and uncomfortable. They have squished too many people in to get more $$$. The staff are not friendly and not wanting to accommodate. I asked for two salads rather than a main meal and was advised no we wont do that. Then asked what I would like for breakfast and given something else anyway. I will not be flying United International anytime soon.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

The flight was fine. It's the satellite terminal that supports American eagle flights is what sucks. There is only one food option and everything there is way overpriced. I mean I know it's airport pricing, but it's even crazier than that. I bought a sandwich in a plastic container for $18.

The flight was really crowded. Flight attendants were just ok.

Flight was delayed for 2 hours, then last minute the change to on time. The satélite location is far and a nightmare to get to.

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

For a 5 1/2 hour flite i considered the "business class" to be subpar. The seats were just ok, no amenities, really nothing more than a long domestic flight. Frankly disappointed.

It would be nice to have some low carb options in the snacks.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

While I didn’t watch much tv I would have liked a few more options of TV series from Apple TV or hbo max ..

Everything you need to know for your flight to Central America

Information on your arrival and departure airports