$180 Find Cheap Flights from Santa Ana to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Central America departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$519
San José
San José3 stops$501
Guatemala City
Guatemala City1 stop$459
Panama City
Panama City2 stops$743
Liberia
Liberia1 stop$622
Managua
Managua2 stops$716
San Pedro Sula
San Pedro Sula1 stop$847
Coxen Hole
Coxen Hole2 stops$846
San Salvador
San Salvador1 stop$519
San José
San José3 stops$501
Guatemala City
Guatemala City1 stop$459
Panama City
Panama City2 stops$743
Liberia
Liberia1 stop$622
Managua
Managua2 stops$716
San Pedro Sula
San Pedro Sula1 stop$847
Coxen Hole
Coxen Hole2 stops$846

Book Cheap Santa Ana to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Central America

Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
6:37 pm - 1:24 pm
SNA
-
GUA
17h 47m
1 stop
American Airlines Logo
1:15 pm - 8:14 am
GUA
-
SNA
19h 59m
2 stops
$459American Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
6:37 pm - 1:24 pm
SNA
-
GUA
17h 47m
1 stop
American Airlines Logo
12:04 pm - 8:14 am
GUA
-
SNA
21h 10m
1 stop
$466American Airlines
Mon, Sep 21 - Tue, Oct 6
Alaska Airlines Logo
4:53 pm - 6:20 am
SNA
-
GUA
12h 27m
2 stops
Alaska Airlines Logo
11:20 am - 9:46 pm
GUA
-
SNA
11h 26m
2 stops
$489Alaska Airlines
Thu, Apr 30 - Thu, May 7
Multiple Airlines Logo
3:23 pm - 11:33 am
SNA
-
SJO
19h 10m
3 stops
Multiple Airlines Logo
7:00 am - 10:08 pm
SJO
-
SNA
16h 08m
2 stops
$501Multiple Airlines
Sat, Jun 13 - Sun, Jun 28
Frontier Logo
8:10 pm - 10:01 am
SNA
-
GUA
12h 51m
2 stops
Frontier Logo
3:47 pm - 3:39 pm
GUA
-
SNA
24h 52m
2 stops
$518Frontier
Thu, May 21 - Fri, Jun 12
Frontier Logo
6:38 pm - 2:45 pm
SNA
-
SAL
19h 07m
1 stop
Frontier Logo
11:05 am - 12:34 pm
SAL
-
SNA
26h 29m
2 stops
$519Frontier
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
4:33 pm - 11:59 pm
SNA
-
SJO
30h 26m
3 stops
Multiple Airlines Logo
1:00 pm - 3:38 pm
SJO
-
SNA
27h 38m
3 stops
$539Multiple Airlines
Thu, Sep 17 - Tue, Oct 6
Alaska Airlines Logo
2:12 pm - 6:20 am
SNA
-
GUA
15h 08m
2 stops
Alaska Airlines Logo
11:20 am - 9:46 pm
GUA
-
SNA
11h 26m
2 stops
$549Alaska Airlines
Thu, Sep 17 - Tue, Oct 6
United Airlines Logo
8:00 am - 6:49 pm
SNA
-
GUA
9h 49m
1 stop
United Airlines Logo
6:15 am - 8:19 pm
GUA
-
SNA
15h 04m
2 stops
$565United Airlines
Mon, Sep 21 - Tue, Oct 6
United Airlines Logo
3:02 pm - 4:37 pm
SNA
-
GUA
24h 35m
2 stops
United Airlines Logo
1:30 am - 12:01 pm
GUA
-
SNA
11h 31m
2 stops
$569United Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Central America flights

Get data-powered insights and trends into flights from Santa Ana to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Ana to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to Central America were found on American Airlines ($514) and Alaska Airlines ($609).

Good to know

Low seasonOctober
Cheapest flight$180
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 39% increase in price.
Flight from John Wayne (Santa Ana) to San Salvador

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Central America

 
Need help choosing which airline to fly with from Santa Ana to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9602 reviews
7.1Entertainment
6.6Food
7.3Comfort
7.7Boarding
8.1Crew
Airline reviews

Due to cancellation of connecting flight (Lufthansa) I didn’t fly with United

2.0 MediocreAnonymous, Apr 2026
SFO - FRA
Read more United Airlines reviews

Due to cancellation of connecting flight (Lufthansa) I didn’t fly with United

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

I had a cancelled flight because of technical issues going to my destination, and a delayed flight coming home. All told it wasn’t a total bust.

The business class seat is exceptional. I wish the food is more palatable.

the entire flight felt off. The crew seemed uninterested and disengaged. The food service was really bad - overcooked, bland, weird food service. They actually woke us up to serve chicken wraps in the middle of the night, after dinner and before breakfast. Made no sense. Ultimately, I was glad they did though, because the breakfast had been held for so long it was inedible. Eggs, potatoes, sausage - all disgusting. We were asked to "honor" the lavatories for premium customers and stay in our own cabin: this was also strange. So people in economy didn't pay enough to use the closest toilet to them??? It's a toilet. All in all, not the experience I have come to expect from United Airlines. The return flight from Paris to SFO was better, btw.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Business class seats felt very cramped compared to other airlines.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports