$135 Find Cheap Flights from Santa Ana to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Central America departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$336
San José
San José2 stops$356
Guatemala City
Guatemala City2 stops$363
Panama City
Panama City2 stops$653
Liberia
Liberia2 stops$552
Managua
Managua2 stops$369
San Pedro Sula
San Pedro Sula2 stops$514
Coxen Hole
Coxen Hole2 stops$703
San Salvador
San Salvador2 stops$336
San José
San José2 stops$356
Guatemala City
Guatemala City2 stops$363
Panama City
Panama City2 stops$653
Liberia
Liberia2 stops$552
Managua
Managua2 stops$369
San Pedro Sula
San Pedro Sula2 stops$514
Coxen Hole
Coxen Hole2 stops$703

Book Cheap Santa Ana to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Central America

Wed, Mar 18 - Thu, Mar 26
Spirit Airlines Logo
10:48 am - 1:48 pm
SNA
-
SAL
26h 00m
2 stops
Spirit Airlines Logo
2:53 pm - 9:53 am
SAL
-
SNA
20h 00m
2 stops
$336Spirit Airlines
Mon, Mar 16 - Tue, Mar 24
Spirit Airlines Logo
10:48 am - 1:48 pm
SNA
-
SAL
26h 00m
2 stops
Spirit Airlines Logo
2:53 pm - 9:53 am
SAL
-
SNA
20h 00m
2 stops
$347Spirit Airlines
Mon, Mar 16 - Tue, Mar 24
Spirit Airlines Logo
2:53 pm - 1:48 pm
SNA
-
SAL
21h 55m
2 stops
Spirit Airlines Logo
2:53 pm - 9:53 am
SAL
-
SNA
20h 00m
2 stops
$352Spirit Airlines
Tue, Mar 3 - Wed, Mar 11
Multiple Airlines Logo
4:37 pm - 12:22 pm
SNA
-
SJO
17h 45m
2 stops
Multiple Airlines Logo
2:50 pm - 9:13 pm
SJO
-
SNA
31h 23m
3 stops
$384Multiple Airlines
Wed, Mar 4 - Wed, Mar 11
Multiple Airlines Logo
4:37 pm - 12:24 pm
SNA
-
GUA
17h 47m
2 stops
Multiple Airlines Logo
1:54 pm - 9:13 pm
GUA
-
SNA
32h 19m
3 stops
$386Multiple Airlines
Sun, Apr 26 - Wed, Apr 29
American Airlines Logo
6:59 pm - 2:30 pm
SNA
-
BZE
18h 31m
1 stop
American Airlines Logo
12:14 pm - 10:45 pm
BZE
-
SNA
11h 31m
1 stop
$399American Airlines
Sun, Apr 26 - Wed, Apr 29
American Airlines Logo
6:59 pm - 2:30 pm
SNA
-
BZE
18h 31m
1 stop
American Airlines Logo
3:31 pm - 10:05 am
BZE
-
SNA
19h 34m
2 stops
$403American Airlines
Sun, Apr 26 - Wed, Apr 29
Southwest Logo
9:10 pm - 12:30 pm
SNA
-
BZE
14h 20m
2 stops
Southwest Logo
1:25 pm - 9:45 pm
BZE
-
SNA
9h 20m
2 stops
$464Southwest
Wed, Apr 15 - Wed, Apr 22
United Airlines Logo
6:39 pm - 12:10 pm
SNA
-
LIR
16h 31m
2 stops
United Airlines Logo
1:20 pm - 9:45 pm
LIR
-
SNA
9h 25m
1 stop
$552United Airlines
Wed, Apr 15 - Wed, Apr 22
United Airlines Logo
6:28 pm - 3:19 pm
SNA
-
LIR
19h 51m
1 stop
United Airlines Logo
1:20 pm - 9:45 pm
LIR
-
SNA
9h 25m
1 stop
$562United Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Central America flights

Get data-powered insights and trends into flights from Santa Ana to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Ana to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to Central America were found on Spirit Airlines ($356) and United Airlines ($552).

Good to know

Low seasonOctober
Cheapest flight$135
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from John Wayne (Santa Ana) to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Central America

 
Need help choosing which airline to fly with from Santa Ana to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9273 reviews
7.7Boarding
8.1Crew
7.3Comfort
7.1Entertainment
6.6Food
Airline reviews

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

6.0 GoodMike, Feb 2026
LAX - NRT
Read more United Airlines reviews

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Terrible. Our first time back on United for 10 years, the seats in Polaris class are small and uncomfortable. They have squished too many people in to get more $$$. The staff are not friendly and not wanting to accommodate. I asked for two salads rather than a main meal and was advised no we wont do that. Then asked what I would like for breakfast and given something else anyway. I will not be flying United International anytime soon.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

The flight crew where really good. Better then the crew from BNE to SFO

Food should be changed in menu Many muslims travels in this airlime they need to add one Halal meal

left on time, reasonable boarding process arrived early luggage came out quickly

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

Flight was delayed for 2 hours, then last minute the change to on time. The satélite location is far and a nightmare to get to.

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

For a 5 1/2 hour flite i considered the "business class" to be subpar. The seats were just ok, no amenities, really nothing more than a long domestic flight. Frankly disappointed.

It would be nice to have some low carb options in the snacks.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

While I didn’t watch much tv I would have liked a few more options of TV series from Apple TV or hbo max ..

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

The flight was very smooth and the meal in business class was great.

I requested a low sodium meal. Reason being, I take medicine for high blood pressure and I wear compression socks on long flights to help with leg swelling. Having less sodium in meals really helps me feel better on long flights. I received my initial low sodium meal after takeoff. Just before landing, the crew came through with the meal cart and offered me what was being served. I said no thank you and then noticed my low sodium meal in the meal cart, with my name and seat assignment on it. I motioned to the crew member, but he grabbed the meal cart and proceeded to move to the rear of the aircraft. He didn’t see me or other passengers who had attempted to get this attention. He was more concerned about completing meal service since we were due to land in under 45 minutes. I pressed the call light five times from my seat to receive help, but no crew member responded to me. So, I didn’t receive a second meal, one that I requested (the low sodium option). This led me to have a migraine from only eating one meal on an 11-hour flight. This is why I’m not a fan of flying US-based airlines overseas. The crew members continue to show the absolute worst customer service experience. I would not recommend flying American for overseas flights.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports