$191 Find Cheap Flights from Santa Ana to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Central America departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Santa Ana to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$509
San José
San José2 stops$492
Guatemala City
Guatemala City2 stops$496
Panama City
Panama City1 stop$721
Liberia
Liberia2 stops$647
Managua
Managua2 stops$691
San Pedro Sula
San Pedro Sula2 stops$539
Coxen Hole
Coxen Hole2 stops$849
San Salvador
San Salvador2 stops$509
San José
San José2 stops$492
Guatemala City
Guatemala City2 stops$496
Panama City
Panama City1 stop$721
Liberia
Liberia2 stops$647
Managua
Managua2 stops$691
San Pedro Sula
San Pedro Sula2 stops$539
Coxen Hole
Coxen Hole2 stops$849

Book Cheap Santa Ana to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Central America

Fri, Apr 17 - Thu, Apr 30
American Airlines Logo
7:20 pm - 2:30 pm
SNA
-
BZE
18h 10m
2 stops
American Airlines Logo
3:31 pm - 10:08 am
BZE
-
SNA
19h 37m
2 stops
$454American Airlines
Wed, May 13 - Tue, May 19
Southwest Logo
7:50 pm - 12:10 pm
SNA
-
SJO
15h 20m
2 stops
Southwest Logo
9:00 am - 9:45 pm
SJO
-
SNA
13h 45m
2 stops
$492Southwest
Tue, Apr 28 - Tue, May 5
United Airlines Logo
6:39 pm - 11:15 am
SNA
-
BZE
15h 36m
2 stops
United Airlines Logo
12:20 pm - 9:31 pm
BZE
-
SNA
10h 11m
1 stop
$493United Airlines
Tue, Apr 7 - Thu, Apr 9
Spirit Airlines Logo
10:48 am - 11:24 am
SNA
-
GUA
23h 36m
2 stops
Spirit Airlines Logo
12:23 pm - 9:53 am
GUA
-
SNA
22h 30m
2 stops
$496Spirit Airlines
Tue, Apr 28 - Tue, May 5
United Airlines Logo
7:44 pm - 11:15 am
SNA
-
BZE
14h 31m
2 stops
United Airlines Logo
12:20 pm - 9:44 am
BZE
-
SNA
22h 24m
2 stops
$498United Airlines
Mon, Apr 6 - Mon, Apr 13
Multiple Airlines Logo
2:53 pm - 5:38 pm
SNA
-
SAL
25h 45m
2 stops
Multiple Airlines Logo
8:00 am - 9:53 am
SAL
-
SNA
26h 53m
2 stops
$509Multiple Airlines
Wed, Apr 8 - Sat, Apr 11
Spirit Airlines Logo
10:48 am - 11:24 am
SNA
-
GUA
23h 36m
2 stops
Spirit Airlines Logo
12:23 pm - 9:53 am
GUA
-
SNA
22h 30m
2 stops
$531Spirit Airlines
Wed, Sep 2 - Tue, Sep 8
Multiple Airlines Logo
8:00 am - 4:37 pm
SNA
-
GUA
7h 37m
1 stop
Multiple Airlines Logo
1:30 am - 11:17 am
GUA
-
SNA
10h 47m
1 stop
$549Multiple Airlines
Tue, Aug 11 - Sat, Aug 29
Copa Airlines Logo
8:00 am - 4:37 pm
SNA
-
GUA
7h 37m
1 stop
Copa Airlines Logo
1:30 am - 11:17 am
GUA
-
SNA
10h 47m
1 stop
$550Copa Airlines
Thu, Sep 10 - Tue, Sep 15
Copa Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
Copa Airlines Logo
10:00 am - 9:53 pm
PTY
-
SNA
13h 53m
1 stop
$721Copa Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Central America flights

Get data-powered insights and trends into flights from Santa Ana to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Ana to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to Central America were found on American Airlines ($494) and United Airlines ($510).

Good to know

Low seasonOctober
Cheapest flight$191
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from John Wayne (Santa Ana) to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Central America

 
Need help choosing which airline to fly with from Santa Ana to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9431 reviews
8.1Crew
7.7Boarding
7.3Comfort
6.6Food
7.1Entertainment
Airline reviews

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

6.0 GoodAnonymous, Mar 2026
SFO - NRT
Read more United Airlines reviews

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Complimentary light meal would be appreciated. But great flight crew service on all legs

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

it was a very short flight so my expectations were low.

Entertainment kept turning itself off. Gave up on watching a movie.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

Dloght delayed by 2.5 hrs . Common theme in my last four american floghts

They are rarely on time! Very hard to plan your travels when flights or connections keep getting delayed.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

The worst Airline ever. They centered my second flight and leave me in NY. They don’t have any representatives at the airport and they don’t respond to calls. Basically I got stuck. I will never purchase through there again.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

Mediocre would be best description. Food bland. Seat biz class uncomfortable to sleep. Crew never dimmed lights completely in an overnight flight to Europe. Would avoid AA if possible.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Massimo, flight attendant was very authentic, attentive - wonderful. Food/wrap was just okay.

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

Everything you need to know for your flight to Central America

Information on your arrival and departure airports