DSM - CHS

$135 Find Cheap Flights from Des Moines to Charleston - Compare and Save

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Everything you should know

Cheapest round-trip
$269
Typical prices: $380-$510
Delta
Sat 10/13Wed 10/17
DSM - CHS • 1 stop
Cheapest one-way
$135
Typical prices: $177-$323
Delta
Sat 10/13
DSM - CHS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Charleston. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
May
Cheapest • 10% price drop
April
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Minneapolis St Paul (MSP)
Cheapest • Avg $361 (round-trip)
Charlotte Douglas (CLT)
Shortest trip • 4h 49m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Des Moines to Charleston (DSM-CHS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Charleston

Tue, Oct 13 - Sat, Oct 17
Delta Logo
6:54 pm - 11:59 pmDSM  Des Moines-CHS Charleston
4h 05m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:02 am - 10:42 amCHS  Charleston-DSM Des Moines
4h 40m1 stop Atlanta Hartsfield-Jackson
$269Delta
Tue, Oct 13 - Sat, Oct 17
Delta Logo
6:54 pm - 11:59 pmDSM  Des Moines-CHS Charleston
4h 05m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:02 am - 10:42 amCHS  Charleston-DSM Des Moines
4h 40m1 stop Atlanta Hartsfield-Jackson
$269Delta
Tue, Nov 3 - Sat, Nov 7
United Airlines Logo
8:00 am - 1:56 pmDSM  Des Moines-CHS Charleston
4h 56m1 stop Chicago O'Hare Intl
United Airlines Logo
3:29 pm - 7:16 pmCHS  Charleston-DSM Des Moines
4h 47m1 stop Chicago O'Hare Intl
$269United Airlines
Tue, Nov 3 - Sat, Nov 7
United Airlines Logo
8:00 am - 1:56 pmDSM  Des Moines-CHS Charleston
4h 56m1 stop Chicago O'Hare Intl
United Airlines Logo
2:52 pm - 9:55 pmCHS  Charleston-DSM Des Moines
8h 03m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$274United Airlines
Wed, Oct 7 - Sat, Oct 10
American Airlines Logo
7:29 am - 3:02 pmDSM  Des Moines-CHS Charleston
6h 33m1 stop Chicago O'Hare Intl
American Airlines Logo
7:16 am - 1:30 pmCHS  Charleston-DSM Des Moines
7h 14m1 stop Chicago O'Hare Intl
$291American Airlines
Wed, Nov 4 - Sat, Nov 7
American Airlines Logo
7:23 am - 3:24 pmDSM  Des Moines-CHS Charleston
7h 01m1 stop Chicago O'Hare Intl
American Airlines Logo
6:10 am - 10:10 amCHS  Charleston-DSM Des Moines
5h 00m1 stop Charlotte Douglas
$291American Airlines
Mon, Feb 22 - Sat, Feb 27
Delta Logo
6:20 am - 12:21 pmDSM  Des Moines-CHS Charleston
5h 01m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:30 pm - 9:24 pmCHS  Charleston-DSM Des Moines
4h 54m1 stop Minneapolis St Paul
$299Delta
Wed, Nov 4 - Sat, Nov 7
United Airlines Logo
8:00 am - 1:56 pmDSM  Des Moines-CHS Charleston
4h 56m1 stop Chicago O'Hare Intl
United Airlines Logo
2:52 pm - 9:55 pmCHS  Charleston-DSM Des Moines
8h 03m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$300United Airlines
Mon, Feb 22 - Sat, Feb 27
Southwest Logo
6:25 am - 6:00 pmDSM  Des Moines-CHS Charleston
10h 35m2 stops Denver Intl Chicago Midway
Southwest Logo
7:25 am - 8:30 pmCHS  Charleston-DSM Des Moines
14h 05m2 stops Dallas Love Field Denver Intl
$332Southwest
Wed, Dec 2 - Sat, Dec 5
Southwest Logo
7:00 am - 4:30 pmDSM  Des Moines-CHS Charleston
8h 30m2 stops Denver Intl Chicago Midway
Southwest Logo
9:45 am - 7:40 pmCHS  Charleston-DSM Des Moines
10h 55m2 stops Nashville Intl Chicago Midway
$335Southwest
Booking Insights

Price, demand and travel trends for Des Moines to Charleston flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Charleston with more confidence.

How much is a round-trip flight from Des Moines to Charleston?

Round-trip flights from Des Moines to Charleston start at $269. Prices are below average for this route right now, with typical round-trip fares ranging from $380 to $510. The lowest price found in the past 5 days was $269 on Delta.

What's the cheapest day of the week to fly from Des Moines to Charleston?

Sunday is the cheapest day of the week to fly from Des Moines to Charleston, it is 11% cheaper than the average day. Thursday is the most expensive day with flight prices 16% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Des Moines to Charleston?

•May is the cheapest month to fly from Des Moines to Charleston at $380 round-trip.
•February ($608) and March ($518) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 60% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Des Moines to Charleston flights

Low season

January

Cheapest flight

$135
Best time to beat the crowds with an average 8% drop in price.
Flight from Des Moines to Charleston

When to book flights from Des Moines to Charleston

Are your dates flexible? Find out the best times to travel from Des Moines to Charleston based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Charleston flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Des Moines to Charleston?

    Flights from Des Moines to Charleston usually depart from Des Moines (DSM) and arrive at Charleston (CHS).

  • What cabin classes can I book on flights from Des Moines to Charleston?

    Two cabin classes are available on flights from Des Moines to Charleston:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Des Moines to Charleston pass through?

    One-stop flights from Des Moines to Charleston most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 40% of one-stop connections
    • Charlotte Douglas (CLT) - 26% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 20% of one-stop connections
    • Chicago Midway (MDW) - 9% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Des Moines to Charleston?

    On the Des Moines to Charleston route, being flexible with your departure day can save you up to 23%. Sunday is the cheapest day at $380 round-trip on average, while Thursday is the most expensive at $492: a $112 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How long is a flight from Des Moines to Charleston?

    A nonstop flight from Des Moines to Charleston takes 0h 00m, covering 956 miles.

  • Do I need a passport to fly from Des Moines to Charleston?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Des Moines to Charleston changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $269 to $1,627. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Des Moines to Charleston looking right now?

    One-way fares from Des Moines to Charleston are currently lower than usual. Average one-way flight prices are about $167, which is 18% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Des Moines to Charleston?

    Flying via Minneapolis St Paul (MSP) gives the shortest average 1-stop total travel time at 4h 47m, compared with 4h 49m via Charlotte Douglas (CLT) and 4h 55m via Detroit Metropolitan Wayne County (DTW).

  • What is the time difference between Des Moines and Charleston?

    Charleston is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Charleston Airport (CHS)?

    Charleston Airport (CHS) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
    • Budget
    • Alamo
    • Economy Rent a Car
    • Avis
    • Thrifty

  • How much should I expect to pay for a Des Moines to Charleston flight?

    Round-trip flights from Des Moines to Charleston range from $380 to $510, with an average of $424 over the past 12 months. Anything below $380 counts as a good deal.

Your guide to booking Des Moines to Charleston flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Sunday departure instead of Thursday. On this route, Sunday flights average $380 - about $112 less than Thursday (23% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Charleston trip for May. Fares historically average $380 round-trip in that month - typically $228 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Des Moines to Charleston

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