Which airports can I use when flying from Des Moines to Charleston?

Flights from Des Moines to Charleston usually depart from Des Moines (DSM) and arrive at Charleston (CHS).

What cabin classes can I book on flights from Des Moines to Charleston?

Only Economy Class is available on flights from Des Moines to Charleston.

Which airports do connecting flights from Des Moines to Charleston pass through?

One-stop flights from Des Moines to Charleston most commonly connect through: • Chicago O'Hare Intl (ORD) - 39% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 22% of one-stop connections • Charlotte Douglas (CLT) - 20% of one-stop connections • Chicago Midway (MDW) - 9% of one-stop connections

Can I save money by using flexible dates for flights from Des Moines to Charleston?

Yes. Flexible dates can save you up to 34% on flights from Des Moines to Charleston. Tuesday is the cheapest departure day at $386 round-trip on average, while Thursday is the most expensive at $580, a difference of $194. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Des Moines to Charleston?

A nonstop flight from Des Moines to Charleston takes 00m, covering 956 miles.

Do I need a passport to fly from Des Moines to Charleston?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Des Moines to Charleston changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $1,668. That means the highest observed fare was about 5x higher than the lowest one.

How are flight prices from Des Moines to Charleston looking right now?

One-way fares from Des Moines to Charleston are currently higher than usual. Average one-way flight prices are about $283, which is 36% above the typical average for this route.

How much time can I save by choosing a different layover airport from Des Moines to Charleston?

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 4h 07m, compared with 4h 47m via Minneapolis St Paul (MSP) and 4h 55m via Detroit Metropolitan Wayne County (DTW).

What is the time difference between Des Moines and Charleston?

Charleston is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Charleston Airport (CHS)?

Charleston Airport (CHS) hosts 5 major car rental companies, with daily rates averaging $78 for economy cars. Top options include: • Budget • Alamo • Economy Rent a Car • Avis • Thrifty

How much should I expect to pay for a Des Moines to Charleston flight?

Round-trip flights from Des Moines to Charleston range from $380 to $543, with an average of $437 over the past 12 months. Anything below $380 counts as a good deal.

How much is a round-trip flight from Des Moines to Charleston?

Round-trip flights from Des Moines to Charleston typically range from $380 to $543. The lowest price found in the past 5 days was $325, on American Airlines.

What's the cheapest day of the week to fly from Des Moines to Charleston?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Des Moines to Charleston. It’s 12% cheaper than the average day, while Thursday is the most expensive, with prices 32% higher.

What’s the cheapest month to fly from Des Moines to Charleston?

•May and October are the cheapest months to fly from Des Moines to Charleston at $380 round-trip. •February ($608) and March ($594) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 60% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Which airline is the cheapest to fly from Des Moines to Charleston?

American Airlines ($325) and Delta ($325) are the cheapest airlines to fly round-trip from Des Moines to Charleston according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Des Moines to Charleston?

Chicago O'Hare Intl (ORD) is the most popular layover for the Des Moines to Charleston route. 39% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Des Moines to Charleston?

Flights via Minneapolis St Paul (MSP) offer the most affordable fares, with an average round-trip price of $366. Based on KAYAK data over the past 3 months.

When flying from Des Moines to Charleston which airport offers the shortest layover?

Nashville Intl (BNA) had the shortest average connection time for Des Moines to Charleston layovers at 2h 32m over the past 3 months.

$213 CHEAP FLIGHTS from Des Moines to Charleston (DSM - CHS)

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$325

Typical prices: $380-$543

American Airlines

Sun 12/2Sun 12/9

DSM - CHS • 1 stop

Cheapest one-way

$163

Typical prices: $170-$291

American Airlines

Sun 2/4

DSM - CHS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Des Moines and Charleston. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

May

Cheapest • 13% price drop

May

Most popular

Good to know

Top layover airports

Minneapolis St Paul (MSP)

Cheapest • Avg $366 (round-trip)

Nashville Intl (BNA)

Shortest trip • 4h 07m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Charleston!

Flight Deals

Cheap Flights from Des Moines to Charleston (DSM-CHS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Des Moines to Charleston

Wed, Dec 2 - Wed, Dec 9

11:09 am - 6:45 pmDSM Des Moines-CHS Charleston

6h 36m1 stop Charlotte Douglas

3:52 pm - 11:00 pmCHS Charleston-DSM Des Moines

8h 08m1 stop Washington, D.C. Reagan-National

$325American Airlines

Wed, Dec 2 - Wed, Dec 9

11:09 am - 6:45 pmDSM Des Moines-CHS Charleston

6h 36m1 stop Charlotte Douglas

3:52 pm - 11:00 pmCHS Charleston-DSM Des Moines

8h 08m1 stop Washington, D.C. Reagan-National

$325American Airlines

Fri, Dec 18 - Fri, Dec 25

6:53 pm - 12:04 amDSM Des Moines-CHS Charleston

4h 11m1 stop Atlanta Hartsfield-Jackson

5:55 pm - 10:38 pmCHS Charleston-DSM Des Moines

5h 43m1 stop Atlanta Hartsfield-Jackson

$325Delta

Mon, Dec 14 - Fri, Dec 18

6:41 am - 2:17 pmDSM Des Moines-CHS Charleston

6h 36m1 stop Minneapolis St Paul

3:14 pm - 9:31 pmCHS Charleston-DSM Des Moines

7h 17m1 stop Minneapolis St Paul

$325Delta

Wed, Dec 2 - Wed, Dec 9

3:20 pm - 9:21 pmDSM Des Moines-CHS Charleston

5h 01m1 stop Chicago O'Hare Intl

10:23 am - 7:19 pmCHS Charleston-DSM Des Moines

9h 56m2 stops Newark Chicago O'Hare Intl

$330United Airlines

Wed, Dec 2 - Wed, Dec 9

6:15 am - 2:00 pmDSM Des Moines-CHS Charleston

6h 45m1 stop Chicago O'Hare Intl

10:23 am - 7:19 pmCHS Charleston-DSM Des Moines

9h 56m2 stops Newark Chicago O'Hare Intl

$330United Airlines

Fri, Dec 18 - Fri, Dec 25

5:10 am - 4:00 pmDSM Des Moines-CHS Charleston

9h 50m2 stops Chicago Midway Baltimore/Washington

8:00 am - 11:25 amCHS Charleston-DSM Des Moines

4h 25m1 stop Chicago Midway

$386Southwest

Fri, Dec 18 - Fri, Dec 25

5:10 am - 4:00 pmDSM Des Moines-CHS Charleston

9h 50m2 stops Chicago Midway Baltimore/Washington

11:00 am - 10:05 pmCHS Charleston-DSM Des Moines

12h 05m2 stops Nashville Intl Chicago Midway

$397Southwest

Mon, Nov 30 - Mon, Dec 7

6:17 pm - 12:31 pmDSM Des Moines-CHS Charleston

17h 14m2 stops Fort Lauderdale Tampa

2:49 pm - 10:21 pmCHS Charleston-DSM Des Moines

8h 32m1 stop Fort Myers SW Florida Intl

$451Multiple Airlines

Mon, Nov 16 - Fri, Nov 20

6:45 am - 8:38 amDSM Des Moines-CHS Charleston

24h 53m2 stops Nashville Intl Orlando

3:14 pm - 10:11 pmCHS Charleston-DSM Des Moines

7h 57m1 stop Fort Myers SW Florida Intl

$494Multiple Airlines

Recent last minute flight deals from Des Moines to Charleston

Mon, Nov 9 - Wed, Nov 18

8:04 pm - 10:10 pmDSM Des Moines-CHS Charleston

25h 06m2 stops Las Vegas Harry Reid Intl Akron/Canton

7:54 pm - 4:11 pmCHS Charleston-DSM Des Moines

21h 17m1 stop Fort Lauderdale

$461Multiple Airlines

Mon, Nov 9 - Fri, Nov 13

8:04 pm - 10:10 pmDSM Des Moines-CHS Charleston

25h 06m2 stops Las Vegas Harry Reid Intl Akron/Canton

3:14 pm - 10:15 pmCHS Charleston-DSM Des Moines

8h 01m1 stop Fort Myers SW Florida Intl

$468Multiple Airlines

Sun, Nov 8 - Wed, Nov 18

12:25 pm - 1:50 pmDSM Des Moines-CHS Charleston

24h 25m2 stops Fort Lauderdale Tampa

7:54 pm - 4:11 pmCHS Charleston-DSM Des Moines

21h 17m1 stop Fort Lauderdale

$514Multiple Airlines

Tue, Nov 10 - Thu, Nov 19

3:31 pm - 10:26 pmDSM Des Moines-CHS Charleston

5h 55m1 stop Dallas/Fort Worth

8:29 pm - 12:26 amCHS Charleston-DSM Des Moines

4h 57m1 stop Charlotte Douglas

$693American Airlines

Tue, Nov 10 - Sat, Nov 14

3:31 pm - 10:26 pmDSM Des Moines-CHS Charleston

5h 55m1 stop Dallas/Fort Worth

5:28 pm - 11:26 pmCHS Charleston-DSM Des Moines

6h 58m1 stop Charlotte Douglas

$693American Airlines

Mon, Nov 9 - Fri, Nov 13

2:59 pm - 8:13 pmDSM Des Moines-CHS Charleston

4h 14m1 stop Atlanta Hartsfield-Jackson

6:34 am - 10:44 amCHS Charleston-DSM Des Moines

5h 10m1 stop Atlanta Hartsfield-Jackson

$827Delta

Sat, Nov 7 - Fri, Nov 13

5:39 am - 11:07 amDSM Des Moines-CHS Charleston

4h 28m1 stop Atlanta Hartsfield-Jackson

3:23 pm - 7:15 pmCHS Charleston-DSM Des Moines

4h 52m1 stop Minneapolis St Paul

$827Delta

Tue, Nov 10 - Fri, Nov 13

8:00 am - 1:56 pmDSM Des Moines-CHS Charleston

4h 56m1 stop Chicago O'Hare Intl

12:18 pm - 5:28 pmCHS Charleston-DSM Des Moines

6h 10m1 stop Chicago O'Hare Intl

$827United Airlines

Sun, Nov 8 - Fri, Nov 13

8:00 am - 1:56 pmDSM Des Moines-CHS Charleston

4h 56m1 stop Chicago O'Hare Intl

4:15 pm - 11:42 pmCHS Charleston-DSM Des Moines

8h 27m1 stop Denver Intl

$827United Airlines

Fri, Nov 6 - Sun, Nov 8

6:40 am - 6:30 pmDSM Des Moines-CHS Charleston

10h 50m2 stops Denver Intl Nashville Intl

1:20 pm - 10:05 pmCHS Charleston-DSM Des Moines

9h 45m2 stops Nashville Intl Denver Intl

$1,181Southwest

Booking Insights

Price, demand and travel trends for Des Moines to Charleston flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Des Moines to Charleston? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Charleston departing in december.
What's the cheapest day of the week to fly from Des Moines to Charleston?: Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Des Moines to Charleston. It’s 12% cheaper than the average day, while Thursday is the most expensive, with prices 32% higher.
What’s the cheapest month to fly from Des Moines to Charleston? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Des Moines to Charleston, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •May and October are the cheapest months to fly from Des Moines to Charleston at $380 round-trip.
•February ($608) and March ($594) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 60% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	January
High season	May
Cheapest flight	$163

Beat the crowds with an average 57% drop in travelers.

The most popular month to fly with an average 69% increase in travelers.

One-way flight from Des Moines to Charleston

When to book flights from Des Moines to Charleston

Are your dates flexible? Find out the best times to travel from Des Moines to Charleston based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Des Moines to Charleston?
Only Economy Class is available on flights from Des Moines to Charleston.
How long is a flight from Des Moines to Charleston?
A nonstop flight from Des Moines to Charleston takes 00m, covering 956 miles.
Do I need a passport to fly from Des Moines to Charleston?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Des Moines to Charleston flight?
Round-trip flights from Des Moines to Charleston range from $380 to $543, with an average of $437 over the past 12 months. Anything below $380 counts as a good deal.
Have flight prices from Des Moines to Charleston changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $1,668. That means the highest observed fare was about 5x higher than the lowest one.
How are flight prices from Des Moines to Charleston looking right now?
One-way fares from Des Moines to Charleston are currently higher than usual. Average one-way flight prices are about $283, which is 36% above the typical average for this route.
What car rental options are available at Charleston Airport (CHS)?
Charleston Airport (CHS) hosts 5 major car rental companies, with daily rates averaging $78 for economy cars. Top options include:

• Budget
• Alamo
• Economy Rent a Car
• Avis
• Thrifty
Which airports can I use when flying from Des Moines to Charleston?
Flights from Des Moines to Charleston usually depart from Des Moines (DSM) and arrive at Charleston (CHS).
Which airports do connecting flights from Des Moines to Charleston pass through?
One-stop flights from Des Moines to Charleston most commonly connect through:

• Chicago O'Hare Intl (ORD) - 39% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 22% of one-stop connections
• Charlotte Douglas (CLT) - 20% of one-stop connections
• Chicago Midway (MDW) - 9% of one-stop connections
Can I save money by using flexible dates for flights from Des Moines to Charleston?
Yes. Flexible dates can save you up to 34% on flights from Des Moines to Charleston. Tuesday is the cheapest departure day at $386 round-trip on average, while Thursday is the most expensive at $580, a difference of $194.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Des Moines to Charleston?
Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 4h 07m, compared with 4h 47m via Minneapolis St Paul (MSP) and 4h 55m via Detroit Metropolitan Wayne County (DTW).
What is the time difference between Des Moines and Charleston?
Charleston is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Tuesday departure and avoid flying on Thursday. On this route, Tuesday flights average $386, about $194 less than Thursday fares (33% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to Charleston trip for May. Fares historically average $380 round-trip in that month - typically $228 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Des Moines to Charleston

Add a hotel or car rental

Airports

Cabin class

Direct Flights

Origins

Other destinations

Return flight

Complete your trip to Charleston with a hotel stay or car rental

Car rentals in Charleston

Hotels in Charleston

Vacations in Charleston

DSM - CHS

$213 Find Cheap Flights from Des Moines to Charleston - Compare and Save

Everything you should know

Cheap Flights from Des Moines to Charleston (DSM-CHS)

Recent round-trip flight deals from Des Moines to Charleston

Recent one-way flight deals from Des Moines to Charleston

Recent last minute flight deals from Des Moines to Charleston

Price, demand and travel trends for Des Moines to Charleston flights

How much is a round-trip flight from Des Moines to Charleston?

What's the cheapest day of the week to fly from Des Moines to Charleston?

What’s the cheapest month to fly from Des Moines to Charleston?

Which airline is the cheapest to fly from Des Moines to Charleston?

What’s the most popular layover airport when flying from Des Moines to Charleston?

What is the cheapest layover airport when flying from Des Moines to Charleston?

When flying from Des Moines to Charleston which airport offers the shortest layover?

Key details for Des Moines to Charleston flights

Low season

High season

Cheapest flight

When to book flights from Des Moines to Charleston

Your Des Moines to Charleston flight questions, answered

Your guide to booking Des Moines to Charleston flights

More options for your flight from Des Moines to Charleston

Complete your trip to Charleston with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Des Moines to Charleston

Find direct flights to and from Des Moines and Charleston

Flights from domestic origins to Charleston

Flights to other popular destinations

Find deals for your return flight