$137 Find Cheap Flights from Chicago Midway Airport to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South America departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Midway to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$529
Bogotá
Bogotá1 stop$318
Santiago
Santiago1 stop$694
Cartagena
Cartagena1 stop$428
Quito
Quito1 stop$417
Belo Horizonte
Belo Horizonte2 stops$685
Lima
Lima2 stops$529
Bogotá
Bogotá1 stop$318
Santiago
Santiago1 stop$694
Cartagena
Cartagena1 stop$428
Quito
Quito1 stop$417
Belo Horizonte
Belo Horizonte2 stops$685

Book Cheap Midway to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South America

Tue, Mar 24 - Mon, Mar 30
Delta Logo
10:49 am - 7:30 pmMDW-BOG
8h 41m1 stop
Delta Logo
2:55 pm - 9:55 amBOG-MDW
19h 00m1 stop
$318Delta
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Wed, Feb 11 - Mon, Feb 16
Delta Logo
6:00 am - 7:30 pmMDW-BOG
12h 30m1 stop
Delta Logo
9:00 am - 10:42 pmBOG-MDW
14h 42m1 stop
$323Delta
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Sun, Mar 15 - Tue, Mar 17
Delta Logo
6:30 am - 8:20 pmMDW-BOG
13h 50m2 stops
Delta Logo
7:00 am - 10:29 pmBOG-MDW
15h 29m2 stops
$328Delta
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Wed, Feb 11 - Sun, Feb 22
Delta Logo
10:46 am - 7:30 pmMDW-BOG
7h 44m1 stop
Delta Logo
3:55 pm - 5:45 pmBOG-MDW
26h 50m1 stop
$330Delta
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Sat, Feb 14 - Sun, Feb 22
Delta Logo
4:13 pm - 2:25 pmMDW-BOG
21h 12m1 stop
Delta Logo
3:55 pm - 5:45 pmBOG-MDW
26h 50m1 stop
$336Delta
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Tue, Feb 10 - Wed, Feb 11
LATAM Airlines Logo
10:48 am - 7:30 pmMDW-BOG
7h 42m1 stop
LATAM Airlines Logo
9:00 am - 10:22 pmBOG-MDW
14h 22m1 stop
$363LATAM Airlines
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Wed, Mar 25 - Mon, Mar 30
LATAM Airlines Logo
10:49 am - 4:45 pmMDW-BOG
29h 56m2 stops
LATAM Airlines Logo
2:55 pm - 9:55 amBOG-MDW
19h 00m1 stop
$372LATAM Airlines
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Sun, Jan 25 - Wed, Feb 11
LATAM Airlines Logo
6:00 am - 8:20 pmMDW-BOG
37h 20m2 stops
LATAM Airlines Logo
7:00 am - 5:29 pmBOG-MDW
11h 29m2 stops
$405LATAM Airlines
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Sun, Feb 8 - Sun, Feb 15
LATAM Airlines Logo
6:00 am - 9:35 pmMDW-UIO
14h 35m1 stop
LATAM Airlines Logo
6:45 pm - 10:42 pmUIO-MDW
28h 57m2 stops
$417LATAM Airlines
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Fri, Dec 12 - Mon, Dec 22
Multiple Airlines Logo
3:52 pm - 10:55 amMDW-MDE
18h 03m1 stop
Multiple Airlines Logo
11:50 am - 9:58 pmMDE-MDW
11h 08m1 stop
$447Multiple Airlines
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Booking Insights

KAYAK's insights & trends for Midway to South America flights

Get data-powered insights and trends into flights from Midway to South America to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South America?

The average price of all round-trip flights from Chicago Midway Airport to South America clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South America on a Monday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Tuesday, and avoid Fridays for better deals.

Good to know

Cheapest flight$137
Flight from Chicago Midway Airport to Medellín Jose Maria Cordova Intl

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $493 on average. Morning departures are around 40% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $822.

Reviews of the top airlines flying from Midway to South America

 
Need help choosing which airline to fly with from Midway to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8010 reviews
7.9Entertainment
7.9Comfort
8.1Boarding
8.5Crew
7.3Food
Airline reviews

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

10.0 ExcellentHartaj, Nov 2025LGA - RDU
Read more Delta reviews

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

It would’ve been nice for all that money to have a more substantial snack for free. I remember once upon a time getting a very nice turkey sandwich with Swiss cheese on whole wheat bread for no charge along with a drink. I guess those days are gone. it’s a little insulting being given a cookie or a bag of baked chips Going forward I’ll just bring my own.

Great. Seamless. Check in agent at kiosk international was amazing and extremely helpful.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

Everything you need to know for your flight to South America

Information on your arrival and departure airports