Find Deals on Flights from Chicago O'Hare International to Panama

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Chicago O'Hare International to Panama

(Round-trip)
Depart: Mon Mar 20 2017 Return: Mon Mar 27 2017 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
2:19p
PTY
9:12p
6h 53m
1 stop
PTY
10:04p
ORD
7:29a
9h 25m
1 stop
Depart: Sat May 6 2017 Return: Thu May 18 2017 Trip spans 13 days
Major Airline
Major Airline
ORD
5:30a
PTY
5:45a
24h 15m
2 stops
PTY
11:32p
ORD
4:10a
28h 38m
2 stops
Depart: Tue Mar 7 2017 Return: Tue Mar 14 2017 Trip spans 7 days
Avianca
Avianca
ORD
9:35a
PTY
9:53a
24h 18m
2 stops
PTY
1:10a
ORD
9:40a
32h 30m
2 stops
Depart: Mon Mar 6 2017 Return: Fri Mar 10 2017 Trip spans 5 days
Aeromexico
Aeromexico
ORD
10:10a
PTY
7:45a
21h 35m
1 stop
PTY
11:15a
ORD
1:10a
13h 55m
1 stop
Depart: Fri Jun 30 2017 Return: Sun Jul 2 2017 Trip spans 3 days
Delta
Delta
ORD
5:45a
PTY
5:30p
11h 45m
1 stop
PTY
4:20a
ORD
12:26p
8h 06m
1 stop
Depart: Fri Apr 7 2017 Return: Sat Apr 15 2017 Trip spans 9 days
United
United
ORD
1:15a
PTY
3:45p
14h 30m
1 stop
PTY
5:45a
ORD
2:17p
8h 32m
1 stop
Depart: Fri Apr 14 2017 Return: Sun Apr 16 2017 Trip spans 3 days
American Airlines
American Airlines
ORD
1:30a
PTY
8:41a
7h 11m
1 stop
PTY
11:26a
ORD
5:10a
17h 44m
1 stop
Depart: Wed May 17 2017 Return: Fri May 19 2017 Trip spans 3 days
Major Airline
Major Airline
ORD
7:35a
PTY
1:37p
30h 02m
2 stops
PTY
2:45a
ORD
5:40a
26h 55m
2 stops
Depart: Wed Mar 8 2017 Return: Tue Mar 14 2017 Trip spans 6 days
Avianca
Avianca
ORD
9:35a
PTY
9:53a
24h 18m
2 stops
PTY
1:10a
ORD
9:40a
32h 30m
2 stops
Depart: Thu Mar 9 2017 Return: Tue Mar 14 2017 Trip spans 5 days
Aeromexico
Aeromexico
ORD
10:10a
PTY
7:45a
21h 35m
1 stop
PTY
12:15p
ORD
8:05p
31h 50m
1 stop
Depart: Mon Apr 3 2017 Return: Mon Apr 17 2017 Trip spans 15 days
Spirit Airlines
Spirit Airlines
ORD
2:19p
PTY
9:12p
6h 53m
1 stop
PTY
10:04p
ORD
7:30a
9h 26m
1 stop
Depart: Sun Jun 4 2017 Return: Sun Jun 11 2017 Trip spans 8 days
Copa Airlines
Copa Airlines
ORD
10:25a
DAV
2:46p
28h 21m
1 stop
DAV
5:34a
ORD
9:07a
27h 33m
1 stop
Depart: Fri Mar 10 2017 Return: Mon Mar 13 2017 Trip spans 3 days
Aeromexico
Aeromexico
ORD
8:35a
PTY
7:45a
23h 10m
2 stops
PTY
12:15p
ORD
9:30p
33h 15m
2 stops
Depart: Sun Mar 5 2017 Return: Fri Mar 10 2017 Trip spans 6 days
Major Airline
Major Airline
ORD
3:55p
PTY
8:26a
16h 31m
2 stops
PTY
6:15a
ORD
3:30p
33h 15m
2 stops
Depart: Sun Mar 19 2017 Return: Wed Mar 22 2017 Trip spans 4 days
Avianca
Avianca
ORD
11:35a
PTY
9:00a
21h 25m
2 stops
PTY
2:00a
ORD
9:40a
7h 40m
1 stop
Depart: Tue Mar 21 2017 Return: Sat Mar 25 2017 Trip spans 5 days
Aeromexico
Aeromexico
ORD
9:25p
PTY
9:45a
12h 20m
1 stop
PTY
12:15p
ORD
8:05p
31h 50m
1 stop
Depart: Wed Apr 5 2017 Return: Mon Apr 17 2017 Trip spans 13 days
Spirit Airlines
Spirit Airlines
ORD
2:19p
PTY
9:04p
6h 45m
1 stop
PTY
10:04p
ORD
7:30a
9h 26m
1 stop
Depart: Wed Mar 29 2017 Return: Tue Apr 4 2017 Trip spans 7 days
Aeromexico
Aeromexico
ORD
9:25p
PTY
9:45a
12h 20m
1 stop
PTY
12:15p
ORD
8:10a
19h 55m
2 stops
Depart: Sat Apr 22 2017 Return: Sat Apr 29 2017 Trip spans 8 days
Avianca
Avianca
ORD
11:35a
PTY
4:46a
17h 11m
2 stops
PTY
6:10p
ORD
9:40a
15h 30m
2 stops
Depart: Mon May 15 2017 Return: Mon May 22 2017 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
3:27a
PTY
9:12p
17h 45m
1 stop
PTY
10:02p
ORD
6:46a
8h 44m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Chicago
$355
Destination

Panama City
$355
David
$866