ORD - TYS

$105 Find Cheap Flights from Chicago O'Hare Airport to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to Knoxville departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$219
Overall average: $289
Multiple Airlines
Wed 4/8Wed 4/15
ORD - TYS • 1 stop
Cheapest non-stop
$227
Typical prices: $232-$389
American Airlines
Tue 4/28Tue 5/5
ORD - TYS • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
United's Economy Plus offers extra legroom benefits.
American's Wi-Fi provides 20 minutes free with ads.
Expert advice
Expert advice
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Top airlines
Cheapest • from $227 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Nonstop flights
You can fly direct with American Airlines and United Airlines. Average duration is 1h 47m
Direct flights
Direct flights
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+1
Direct flights
Direct flights
+1
When to book
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 20% compared to booking last minute.
Insights
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Insights
When to travel
Cheapest • 18% price drop
Most popular
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Flight Deals
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Flight Deals

Cheap Flights from O'Hare Intl to Knoxville (ORD-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to Knoxville

Wed, Apr 8 - Wed, Apr 15
Multiple Airlines Logo
6:10 pm - 10:05 pm
ORD
-
TYS
26h 55m
1 stop
Multiple Airlines Logo
4:25 pm - 9:17 pm
TYS
-
ORD
29h 52m
1 stop
$219Multiple Airlines
Tue, Apr 28 - Tue, May 5
American Airlines Logo
8:30 am - 11:18 am
ORD
-
TYS
1h 48mnonstop
American Airlines Logo
11:31 am - 12:35 pm
TYS
-
ORD
2h 04mnonstop
$227American Airlines
Sat, Apr 11 - Mon, Apr 13
American Airlines Logo
8:30 am - 11:18 am
ORD
-
TYS
1h 48mnonstop
American Airlines Logo
8:48 pm - 9:57 pm
TYS
-
ORD
2h 09mnonstop
$228American Airlines
Sat, Apr 11 - Sat, Apr 18
United Airlines Logo
7:15 am - 10:06 am
ORD
-
TYS
1h 51mnonstop
United Airlines Logo
7:00 am - 7:55 am
TYS
-
ORD
1h 55mnonstop
$229United Airlines
Wed, Apr 8 - Sun, Apr 12
United Airlines Logo
10:30 am - 1:14 pm
ORD
-
TYS
1h 44mnonstop
United Airlines Logo
7:00 am - 7:55 am
TYS
-
ORD
1h 55mnonstop
$231United Airlines
Tue, Mar 31 - Sat, Apr 4
American Airlines Logo
8:05 am - 10:48 am
ORD
-
TYS
1h 43mnonstop
American Airlines Logo
6:05 am - 10:57 am
TYS
-
ORD
5h 52m
1 stop
$234American Airlines
Tue, Apr 14 - Wed, Apr 15
Multiple Airlines Logo
6:10 pm - 10:36 am
ORD
-
TYS
15h 26m
1 stop
Multiple Airlines Logo
4:25 pm - 12:24 am
TYS
-
ORD
8h 59m
1 stop
$238Multiple Airlines
Sat, Apr 4 - Tue, Apr 7
Southwest Logo
2:40 pm - 9:05 pm
ORD
-
TYS
5h 25m
1 stop
Southwest Logo
7:05 am - 12:50 pm
TYS
-
ORD
6h 45m
1 stop
$239Southwest
Mon, Apr 20 - Wed, Apr 22
Multiple Airlines Logo
11:28 am - 9:40 am
ORD
-
TYS
21h 12m
2 stops
Multiple Airlines Logo
4:25 pm - 12:24 am
TYS
-
ORD
8h 59m
1 stop
$241Multiple Airlines
Tue, Apr 14 - Thu, Apr 16
Multiple Airlines Logo
6:10 pm - 10:36 am
ORD
-
TYS
15h 26m
1 stop
Multiple Airlines Logo
3:35 pm - 12:24 am
TYS
-
ORD
9h 49m
1 stop
$242Multiple Airlines
Booking Insights

KAYAK's insights & trends for O'Hare Intl to Knoxville flights

Get data-powered insights and trends into flights from O'Hare Intl to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Chicago O'Hare Airport to Knoxville?

The average price of all round-trip flights from Chicago O'Hare Intl Airport to Knoxville clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Knoxville on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Friday is the most expensive day to fly from Chicago O'Hare Airport to Knoxville. For your return ticket, we recommend flying on a Friday and avoiding Mondays for the best deals.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to Knoxville is August, where tickets cost $256 (return) on average. On the other hand, the most expensive months are October and December, where the average cost of round-trip tickets is $364 and $360 respectively.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to Knoxville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $291 on average.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to Knoxville, you should book around 2 weeks before departure, which saves you about 20% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Expert advice

Expert advice for your flight from O'Hare Intl to Knoxville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on American Airlines

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Good to know

Low seasonDecember
Cheapest flight$105
Best time to beat the crowds but there is an average 15% increase in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Chicago O'Hare Airport to Knoxville

When to book flights from O'Hare Intl to Knoxville

Are your dates flexible? Find out the best times to travel from O'Hare Intl to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Chicago O'Hare Airport to Knoxville flights

  • Which car rental companies are found in Knoxville Airport (TYS)?

    There are many different car rental companies to choose from when you are looking for a rental car at Knoxville Airport. Alamo, Avis, Budget, Enterprise, Hertz, National, and Dollar all have rental locations at Knoxville Airport. You can also find Payless Car Rental at Knoxville Airport.

  • Are there hotels at TYS?

    Yes, there are several hotels inside the Knoxville McGhee Tyson Airport.Options for hotel accommodations with airport shuttle include Best Western Knoxville Airport/Alcoa, Fairfield Inn & Suites, and The Tennessean Hotel among others.

  • Are there pet relief areas at TYS?

    Yes, the Tyler Airport offers a Service Animal Relief Area for passengers traveling with service animals. The relief area is located outside the lower level of the terminal building. The relief station provides a clean, safe and comfortable space for service animals to relieve themselves after a flight.

  • Can I get power plug-in spots in both airports?

    Yes, both airports offer passengers power plugin spots. Chicago O'Hare Airport has Twenty-four charging stations located in O'Hare Multi-Modal Facility​ level 4. There are several power plug-in spots throughout Knoxville McGhee Tyson Airport (TYS) terminal.

  • What is the cheapest flight from Chicago O'Hare Intl Airport to Knoxville?

    In the last 3 days, the lowest price for a flight from Chicago O'Hare Intl Airport to Knoxville was $105 for a one-way ticket and $219 for a round-trip.

  • Do I need a passport to fly between Chicago O'Hare Airport and Knoxville?

    A passport is not required to fly from Chicago O'Hare Airport to Knoxville.

  • Which airlines offer Wi-Fi service onboard planes from Chicago O'Hare Airport to Knoxville?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the Chicago O'Hare Airport to Knoxville flight route.

  • Which aircraft models fly most regularly from Chicago O'Hare Airport to Knoxville?

    The Canadair (Bombardier) Regional Jet 700 is the aircraft model that flies most regularly on the Chicago O'Hare Airport to Knoxville flight route.

  • Which airline alliances offer flights from Chicago O'Hare Airport to Knoxville?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Chicago O'Hare Airport and Knoxville, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Chicago O'Hare Airport to Knoxville?

    There are nonstop flights from Chicago O'Hare Airport to Knoxville on a daily basis.

  • Which is the best airline for flights from Chicago to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Knoxville are Delta and United Airlines. With an average price for the route of $208 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $315 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Chicago O'Hare Airport is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Chicago O'Hare Airport with another airline. Booking your flights between Chicago O'Hare Airport and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Chicago O'Hare Airport up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago O'Hare Intl Airport to Knoxville

  • Looking for a cheap flight? 25% of our users found flights on this route for $168 or less one-way and $233 or less round-trip.
  • When flying from Chicago O'Hare Airport (ORD) to Knoxville, you’re likely to fly into Knoxville McGhee Tyson Airport (TYS). The airport which is a hub for Allegiant Air, has international flights, along with domestic flights to bigger US cities. Travelers may also use Asheville Regional Airport which is 85.5 miles from Knoxville.
  • If you want a chance to see more of the world than you would if you took a direct flight, consider booking a flight with Delta airlines which makes stops at Atlanta Hartsfield - Jackson (ATL) or Detroit Metropolitan (DTW). Also, American Airlines stop at Washington DC Reagan (DCA) and/or Charlotte Douglas (CLT).
  • If you need a convenient place to leave your car while away at Knoxville, you can leave it at Chicago O'Hare Airport economy parking. If you want covered parking, head to the Multi-Modal Facility​ floors 4 & 5, economy Lot F. Other long-term parking lots are Economy Lot G located northeast of the domestic terminals and southwest of Mannheim and Zemke Road. Another long-term parking option is offered at Economy Lot H.
  • If you want to stay healthy and relaxed while on the go, yoga can help to reduce stress and anxiety. The 15 x 16-foot Yoga room at Chicago O'Hare Airport can offer you a much-needed source of calm before your flight. It is situated at the Mezzanine Level of the Terminal 3 Rotunda​. It also features huge monitor displays to show yoga techniques in addition to soothing sounds.
  • Chicago O'Hare Airport has mother's rooms/lactation pods in each terminal. You can find lactation rooms at Terminals 1, 2, & 3. Mothers' rooms are found in terminals 1, 2, 3, and 5. Also, there are two mothers' rooms at Multi-Modal Facility level 1. Each mother’s room is equipped with a comfortable chair, a diaper-changing surface, and is ADA-compliant. This is especially important given the sensitive nature of breastfeeding and pumping.

Prefer to fly direct from Chicago O'Hare Airport to Knoxville?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Chicago O'Hare Intl to Knoxville McGhee Tyson.
Find which airlines fly direct from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport, which days they fly and book direct flights.

Direct departures

Chicago O'Hare Intl to Knoxville McGhee Tyson

Monday

American Airlines,United Airlines

American Airlines,United Airlines

Tuesday

American Airlines,United Airlines

American Airlines,United Airlines

Wednesday

American Airlines,United Airlines

American Airlines,United Airlines

Thursday

American Airlines,United Airlines

American Airlines,United Airlines

Friday

American Airlines,United Airlines

American Airlines,United Airlines

Saturday

American Airlines,United Airlines

American Airlines,United Airlines

Sunday

American Airlines,United Airlines

American Airlines,United Airlines

See more direct flights

Direct returns

Knoxville McGhee Tyson to Chicago O'Hare Intl

Monday

American Airlines,United Airlines

American Airlines,United Airlines

Tuesday

American Airlines,United Airlines

American Airlines,United Airlines

Wednesday

American Airlines,United Airlines

American Airlines,United Airlines

Thursday

American Airlines,United Airlines

American Airlines,United Airlines

Friday

American Airlines,United Airlines

American Airlines,United Airlines

Saturday

American Airlines,United Airlines

American Airlines,United Airlines

Sunday

American Airlines,United Airlines

American Airlines,United Airlines

See more direct flights

Reviews of the top 3 airlines serving from O'Hare Intl to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from O'Hare Intl to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8293 reviews
8.5Crew
7.8Entertainment
7.2Food
7.9Comfort
8.1Boarding
Airline reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

2.0 MediocreSusan, Mar 2026
JAX - ATL
Read more Delta reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

The flight was flying with 30% capacity. The flight my seat from preferred seating to back of the seat. Even though i can understand that this was to balance the flight weight. The flight attendance decided to do the serving near my seat and in the middle , their noices woke me up from sleep , when i realized that the service has ended and when they were going back asked for a coffee, for which they answered they have completed teh service in my location. That really upset me as they woke me up and also rejected the coffee i asked. I ended up landing with a headache, thanks to the crew that screwed up my travel

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

I understand weather is an issue, but making us chase our plane down at five scheduled gates across three terminals in an airport the size of O'Hare was unfair. They'd have probably been better off to leave gates as TBD until the inbound plane is in final approach instead of running us all over the place. Also, props to the consistently-unprepared ground crew in Richmond for once again leaving my lane parked short of the gate because they couldn't have a crew in place on time with 2 hours notice...

cabin crew was OK, food was OK, the trip from the US to Munich was actually pretty bad comfort wise. Noisy aircraft, lights never dimmed even in Business class (night flight) barely sufficient amenities for the price. I have millions of miles with United but TBH American is gaining ground and Delta has always been marginally better then United although on paper United has more longes and cheaper upgrades.

The gate got changed several times and the flight was delayed over an hour. Awful experience

American continues to decline in their customer service and its beyond disappointing.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Maintenance took a very long time and then we were in a holding pattern. While a one-off maintenance issue is standard, there were delays on both of my flights for this trip based on maintenance issues with the planes, which delayed both flights over 45 minutes. Thankfully, I didn't have any connections but it wasn't an experience that would make me pick AA if I have other options.

No Snacks or Entertainment. The flight was short, snacks should still be given.

See prior comment about how Kayak mishandled my reservation and delayed my arrival by 6 hours.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

Everything you need to know for your flight from O'Hare Intl to Knoxville

Information on your arrival and departure airports