Which airports can I use when flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra usually depart from Chicago O'Hare Intl (ORD) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

Which airports do connecting flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra pass through?

Connecting flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra most commonly pass through: • Panama City Tocumen Intl (PTY) - 95% of one-stop connections • Bogotá El Dorado (BOG) - 5% of one-stop connections

Can I save money by using flexible dates for flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Yes. Flexible dates can save you up to 31% on flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra. Monday is the cheapest departure day at $614 round-trip on average, while Wednesday is the most expensive at $887, a difference of $273. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Do I need a passport to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

How much time can I save by choosing a different layover airport from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 13h 45m, compared with 22h 23m via Bogotá El Dorado (BOG).

What is the time difference between Chicago O'Hare Intl Airport and Santa Cruz de la Sierra?

Santa Cruz de la Sierra is 2 hours ahead of Chicago O'Hare Intl Airport (Bolivia Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

How much should I expect to pay for a Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flight?

Round-trip flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra range from $642 to $953, with an average of $829 over the past 12 months. Anything below $642 counts as a good deal.

How much is a round-trip flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Round-trip flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra typically range from $642 to $953. The lowest price found in the past 5 days was $683, on United Airlines.

Which airline is the cheapest to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

United Airlines ($683) and Copa Airlines ($747) are the cheapest airlines to fly round-trip from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Panama City Tocumen Intl (PTY) is the most popular layover for the Chicago O'Hare Intl Airport to Santa Cruz de la Sierra route. 95% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via PTY.

What is the cheapest layover airport when flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Flights via Bogotá El Dorado (BOG) offer the most affordable fares, with an average round-trip price of $768. Based on KAYAK data over the past 3 months.

When flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra which airport offers the shortest layover?

Panama City Tocumen Intl (PTY) had the shortest average connection time for Chicago O'Hare Intl Airport to Santa Cruz de la Sierra layovers at 8h 38m over the past 3 months.

$300 CHEAP FLIGHTS from Chicago to Santa Cruz de la Sierra (ORD - VVI)

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Cheapest round-trip

$683

Typical prices: $642-$953

United Airlines

Sun 11/18Sun 12/9

ORD - VVI • 2 stops

Cheapest one-way

$300

Typical prices: $301-$528

Copa Airlines

Sun 4/1

ORD - VVI • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Chicago O'Hare Intl Airport and Santa Cruz de la Sierra. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

April

Cheapest • 26% price drop

April

Most popular

Good to know

Top layover airports

Bogotá El Dorado (BOG)

Cheapest • Avg $768 (round-trip)

Panama City Tocumen Intl (PTY)

Shortest trip • 13h 45m (one-way)

Insights

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We hope you love your trip to Santa Cruz de la Sierra!

Flight Deals

Cheap Flights from Chicago to Santa Cruz de la Sierra (ORD-VVI)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Chicago to Santa Cruz de la Sierra

Wed, Nov 18 - Wed, Dec 9

7:00 am - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

37h 38m2 stops Newark Panama City Tocumen Intl

11:34 am - 9:37 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

24h 03m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$683United Airlines

Fri, Nov 13 - Mon, Nov 16

5:30 am - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

15h 08m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:41 am - 10:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

24h 30m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$716United Airlines

Sun, Dec 6 - Sat, Jan 23

5:45 am - 10:48 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

15h 03m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:53 am - 10:10 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

24h 17m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$716United Airlines

Sat, Dec 5 - Sat, Jan 23

6:15 pm - 10:48 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 33m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

11:53 am - 10:10 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

24h 17m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$716United Airlines

Wed, Nov 18 - Wed, Dec 9

2:13 pm - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

30h 25m1 stop Panama City Tocumen Intl

11:34 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 37m1 stop Panama City Tocumen Intl

$747Copa Airlines

Mon, Dec 7 - Thu, Jan 21

10:30 pm - 2:40 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 10m1 stop Bogotá El Dorado

3:45 am - 8:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

18h 45m1 stop Bogotá El Dorado

$769Avianca

Sat, Dec 5 - Thu, Jan 21

10:30 pm - 2:40 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 10m1 stop Bogotá El Dorado

3:45 am - 8:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

18h 45m1 stop Bogotá El Dorado

$769Avianca

Mon, Dec 7 - Mon, Jan 18

10:30 pm - 2:40 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 10m1 stop Bogotá El Dorado

3:45 am - 8:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

18h 45m1 stop Bogotá El Dorado

$771Avianca

Wed, Nov 18 - Wed, Dec 9

7:35 am - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

13h 03m1 stop Panama City Tocumen Intl

11:42 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 29m1 stop Panama City Tocumen Intl

$778Copa Airlines

Wed, Nov 18 - Wed, Dec 9

2:13 pm - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

30h 25m1 stop Panama City Tocumen Intl

11:34 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 37m1 stop Panama City Tocumen Intl

$797Copa Airlines

Recent last minute flight deals from Chicago to Santa Cruz de la Sierra

Mon, Nov 9 - Sat, Nov 14

6:55 am - 2:40 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

41h 45m2 stops Houston George Bush Intcntl Bogotá El Dorado

11:41 am - 9:10 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

23h 29m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$715Multiple Airlines

Mon, Nov 9 - Mon, Nov 16

6:55 am - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 42m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:41 am - 10:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

24h 30m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$716United Airlines

Wed, Nov 4 - Wed, Nov 11

2:13 pm - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

11h 24m1 stop Panama City Tocumen Intl

11:41 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 30m1 stop Panama City Tocumen Intl

$718Copa Airlines

Wed, Nov 4 - Wed, Nov 11

10:32 am - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

15h 05m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

11:41 am - 12:45 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

15h 04m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$719United Airlines

Sun, Nov 8 - Mon, Nov 16

7:29 am - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 08m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:41 am - 11:38 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

25h 57m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$903United Airlines

Mon, Nov 9 - Fri, Nov 13

10:30 pm - 2:40 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 10m1 stop Bogotá El Dorado

3:45 am - 7:50 pmVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

18h 05m2 stops Bogotá El Dorado Miami

$931Avianca

Mon, Nov 9 - Sun, Nov 15

10:30 pm - 2:40 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 10m1 stop Bogotá El Dorado

3:45 am - 11:25 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

33h 40m2 stops Bogotá El Dorado Miami

$962Avianca

Sun, Nov 8 - Sun, Nov 15

6:00 am - 6:00 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

34h 00m2 stops Baltimore/Washington Miami

1:08 am - 12:46 pmVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

13h 38m1 stop Panama City Tocumen Intl

$1,130Multiple Airlines

Mon, Nov 9 - Sat, Nov 14

7:35 am - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

13h 03m1 stop Panama City Tocumen Intl

11:41 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 30m1 stop Panama City Tocumen Intl

$1,219Copa Airlines

Mon, Nov 9 - Mon, Nov 16

7:35 am - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

13h 03m1 stop Panama City Tocumen Intl

11:41 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 30m1 stop Panama City Tocumen Intl

$1,364Copa Airlines

Booking Insights

Price, demand and travel trends for Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra departing in november.
What's the cheapest day of the week to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?: Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra. It’s 26% cheaper than the average day, while Wednesday is the most expensive, with prices 6% higher.

Find deals

Low season	September
High season	April
Cheapest flight	$300

Beat the crowds with an average 66% drop in travelers.

The most popular month to fly with an average 48% increase in travelers.

One-way flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra

When to book flights from Chicago to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Chicago to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?
Three cabin classes are available on flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra:

• Economy Class
• Business Class
• First Class
How long is a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?
A nonstop flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra takes 00m, covering 4,410 miles.
Do I need a passport to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
How much should I expect to pay for a Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flight?
Round-trip flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra range from $642 to $953, with an average of $829 over the past 12 months. Anything below $642 counts as a good deal.
Have flight prices from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $683 to $2,739. That means the highest observed fare was about 4x higher than the lowest one.
How are flight prices from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra looking right now?
One-way fares from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra are currently higher than usual. Average one-way flight prices are about $584, which is 52% above the typical average for this route.
Which airports can I use when flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?
Flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra usually depart from Chicago O'Hare Intl (ORD) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).
Which airports do connecting flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra pass through?
Connecting flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra most commonly pass through:

• Panama City Tocumen Intl (PTY) - 95% of one-stop connections
• Bogotá El Dorado (BOG) - 5% of one-stop connections
Can I save money by using flexible dates for flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?
Yes. Flexible dates can save you up to 31% on flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra. Monday is the cheapest departure day at $614 round-trip on average, while Wednesday is the most expensive at $887, a difference of $273.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?
Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 13h 45m, compared with 22h 23m via Bogotá El Dorado (BOG).
What is the time difference between Chicago O'Hare Intl Airport and Santa Cruz de la Sierra?
Santa Cruz de la Sierra is 2 hours ahead of Chicago O'Hare Intl Airport (Bolivia Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Monday departure and avoid flying on Wednesday. On this route, Monday flights average $614, about $273 less than Wednesday fares (31% savings) based on the last 12 months.
If you can choose when to travel, plan your Chicago O'Hare Intl Airport to Santa Cruz de la Sierra trip for April. Fares historically average $610 round-trip in that month - typically $566 less than the most expensive month, which is December (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Cruz de la Sierra Viru Viru Intl Airport.

• Sun Hotel

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ORD - VVI

$300 Find Cheap Flights from Chicago to Santa Cruz de la Sierra - Compare and Save

Everything you should know

Cheap Flights from Chicago to Santa Cruz de la Sierra (ORD-VVI)

Recent round-trip flight deals from Chicago to Santa Cruz de la Sierra

Recent one-way flight deals from Chicago to Santa Cruz de la Sierra

Recent last minute flight deals from Chicago to Santa Cruz de la Sierra

Price, demand and travel trends for Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flights

How much is a round-trip flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

What's the cheapest day of the week to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Which airline is the cheapest to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

What’s the most popular layover airport when flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

What is the cheapest layover airport when flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

When flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra which airport offers the shortest layover?

Key details for Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flights

Low season

High season

Cheapest flight

When to book flights from Chicago to Santa Cruz de la Sierra

Your Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flight questions, answered

Your guide to booking Chicago O'Hare Intl Airport to Santa Cruz de la Sierra flights

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Flights from domestic origins to Santa Cruz de la Sierra

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