Find Deals on Flights from Des Moines to Jacksonville (DSM - JAX)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Jacksonville

(Round-trip)
Depart: Tue Jun 6 2017 Return: Tue Jun 13 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
11:25a
JAX
6:50p
7h 25m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
Depart: Fri May 5 2017 Return: Tue May 9 2017 Trip spans 5 days
Delta
Delta
DSM
1:11p
JAX
5:50p
4h 39m
1 stop
JAX
2:40p
DSM
8:00p
5h 20m
1 stop
Depart: Sun Jul 23 2017 Return: Sat Jul 29 2017 Trip spans 7 days
Major Airline
Major Airline
DSM
2:00a
JAX
3:01a
1h 01m
1 stop
JAX
2:00a
DSM
5:01a
3h 01m
1 stop
Depart: Sat Jul 22 2017 Return: Sun Jul 30 2017 Trip spans 9 days
United
United
DSM
1:15a
JAX
5:40a
4h 25m
1 stop
JAX
12:58p
DSM
5:47p
4h 49m
1 stop
Depart: Wed Aug 23 2017 Return: Wed Aug 30 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
11:20a
JAX
4:12p
4h 52m
1 stop
JAX
5:07a
DSM
11:42a
6h 35m
1 stop
Depart: Sat May 13 2017 Return: Sun May 21 2017 Trip spans 9 days
Delta
Delta
DSM
10:32a
JAX
3:29p
4h 57m
1 stop
JAX
2:00a
DSM
7:50a
5h 50m
1 stop
Depart: Fri Sep 15 2017 Return: Sat Sep 23 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
9:40a
JAX
2:17p
4h 37m
1 stop
JAX
5:07a
DSM
11:42a
6h 35m
1 stop
Depart: Wed May 17 2017 Return: Sun May 21 2017 Trip spans 5 days
Delta
Delta
DSM
1:45a
JAX
8:47a
7h 02m
1 stop
JAX
2:00a
DSM
7:50a
5h 50m
1 stop
Depart: Fri Jun 2 2017 Return: Tue Jun 6 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
1:15p
JAX
6:47p
5h 32m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
Depart: Thu May 4 2017 Return: Fri May 5 2017 Trip spans 2 days
Delta
Delta
DSM
1:45a
JAX
8:47a
7h 02m
1 stop
JAX
2:30a
DSM
7:50a
5h 20m
1 stop
Depart: Thu Apr 27 2017 Return: Fri Apr 28 2017 Trip spans 2 days
Major Airline
Major Airline
DSM
1:00a
JAX
2:01a
1h 01m
1 stop
JAX
1:00a
DSM
4:01a
3h 01m
1 stop
Depart: Mon May 8 2017 Return: Fri May 19 2017 Trip spans 12 days
Delta
Delta
DSM
1:11p
JAX
6:49p
5h 38m
1 stop
JAX
3:30a
DSM
7:50a
4h 20m
1 stop
Depart: Tue Jun 20 2017 Return: Tue Jun 27 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
11:25a
JAX
4:42p
5h 17m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
Depart: Wed Jun 21 2017 Return: Tue Jun 27 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
1:15p
JAX
6:47p
5h 32m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
Depart: Fri May 19 2017 Return: Sat May 27 2017 Trip spans 9 days
Delta
Delta
DSM
1:11p
JAX
5:50p
4h 39m
1 stop
JAX
2:40p
DSM
8:38p
5h 58m
1 stop
Depart: Sat Jun 10 2017 Return: Sat Jun 17 2017 Trip spans 8 days
Delta
Delta
DSM
10:32a
JAX
4:38p
6h 06m
1 stop
JAX
12:25p
DSM
5:29p
5h 04m
1 stop
Depart: Mon Jun 19 2017 Return: Tue Jun 27 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
11:25a
JAX
4:42p
5h 17m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
Depart: Sat Jun 17 2017 Return: Tue Jun 27 2017 Trip spans 11 days
American Airlines
American Airlines
DSM
12:05p
JAX
5:01p
4h 56m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
Depart: Thu Apr 13 2017 Return: Fri Apr 14 2017 Trip spans 2 days
Delta
Delta
DSM
1:45a
JAX
7:30a
5h 45m
1 stop
JAX
2:31p
DSM
7:45p
5h 14m
1 stop
Depart: Fri Jun 23 2017 Return: Tue Jun 27 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
1:15p
JAX
6:47p
5h 32m
1 stop
JAX
6:40a
DSM
11:48a
5h 08m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$331
Destination

Jacksonville
$331