Find Cheap Flights from Des Moines to Jacksonville (DSM - JAX)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
Compare vs. KAYAK all | none
Browse Origins:
Browse Destinations:

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Des Moines to Jacksonville

(Round-trip)
Depart: Wed Sep 27 2017 Return: Sat Sep 30 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
11:20a
JAX
6:37p
7h 17m
1 stop
JAX
5:07a
DSM
11:42a
6h 35m
1 stop
Depart: Mon Jul 24 2017 Return: Tue Jul 25 2017 Trip spans 2 days
Major Airline
Major Airline
DSM
1:00a
JAX
2:01a
1h 01m
1 stop
JAX
1:00a
DSM
4:01a
3h 01m
1 stop
Depart: Thu Nov 2 2017 Return: Tue Nov 7 2017 Trip spans 6 days
United
United
DSM
7:23a
JAX
12:00p
4h 37m
1 stop
JAX
11:28a
DSM
4:26p
4h 58m
1 stop
Depart: Thu Jun 22 2017 Return: Wed Jun 28 2017 Trip spans 7 days
Delta
Delta
DSM
1:59a
JAX
6:45a
4h 46m
1 stop
JAX
2:30a
DSM
8:15a
5h 45m
1 stop
Depart: Thu Aug 31 2017 Return: Sun Sep 3 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
3:00a
JAX
9:35a
6h 35m
1 stop
JAX
4:00a
DSM
10:01a
6h 01m
1 stop
Depart: Sat Nov 4 2017 Return: Tue Nov 7 2017 Trip spans 4 days
United
United
DSM
7:23a
JAX
12:00p
4h 37m
1 stop
JAX
11:28a
DSM
4:26p
4h 58m
1 stop
Depart: Wed Jul 26 2017 Return: Thu Jul 27 2017 Trip spans 2 days
Delta
Delta
DSM
12:50p
JAX
8:04p
7h 14m
1 stop
JAX
8:24a
DSM
1:14p
4h 50m
1 stop
Depart: Sat Jun 24 2017 Return: Wed Jun 28 2017 Trip spans 5 days
Major Airline
Major Airline
DSM
2:00a
JAX
3:01a
1h 01m
1 stop
JAX
2:00a
DSM
5:01a
3h 01m
1 stop
Depart: Thu Aug 17 2017 Return: Thu Aug 24 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
2:14a
JAX
8:05a
5h 51m
1 stop
JAX
5:07a
DSM
10:07a
5h 00m
1 stop
Depart: Sun Nov 5 2017 Return: Wed Nov 8 2017 Trip spans 4 days
United
United
DSM
1:15a
JAX
5:40a
4h 25m
1 stop
JAX
1:30a
DSM
6:20a
4h 50m
1 stop
Depart: Fri Jul 21 2017 Return: Tue Jul 25 2017 Trip spans 5 days
Delta
Delta
DSM
12:50p
JAX
8:05p
7h 15m
1 stop
JAX
2:45p
DSM
7:45p
5h 00m
1 stop
Depart: Tue Jul 25 2017 Return: Wed Jul 26 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
11:25a
JAX
4:42p
5h 17m
1 stop
JAX
3:00a
DSM
8:15a
5h 15m
1 stop
Depart: Mon Nov 6 2017 Return: Thu Nov 9 2017 Trip spans 4 days
United
United
DSM
3:09a
JAX
8:04a
4h 55m
1 stop
JAX
11:28a
DSM
4:26p
4h 58m
1 stop
Depart: Sun Jun 18 2017 Return: Fri Jun 23 2017 Trip spans 6 days
Major Airline
Major Airline
DSM
2:00a
JAX
3:01a
1h 01m
nonstop
JAX
2:00a
DSM
5:01a
3h 01m
nonstop
Depart: Sun Jul 23 2017 Return: Tue Jul 25 2017 Trip spans 3 days
Delta
Delta
DSM
2:00a
JAX
8:39a
6h 39m
1 stop
JAX
2:45p
DSM
7:45p
5h 00m
1 stop
Depart: Tue Nov 7 2017 Return: Fri Nov 10 2017 Trip spans 4 days
United
United
DSM
9:55a
JAX
2:55p
5h 00m
1 stop
JAX
1:30a
DSM
6:20a
4h 50m
1 stop
Depart: Fri Nov 3 2017 Return: Tue Nov 7 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
11:20a
JAX
6:37p
7h 17m
1 stop
JAX
5:30a
DSM
10:42a
5h 12m
1 stop
Depart: Sat Nov 25 2017 Return: Tue Nov 28 2017 Trip spans 4 days
Delta
Delta
DSM
11:50a
JAX
6:39p
6h 49m
1 stop
JAX
11:00a
DSM
6:07p
7h 07m
1 stop
Depart: Wed Nov 8 2017 Return: Sat Nov 11 2017 Trip spans 4 days
United
United
DSM
3:09a
JAX
8:04a
4h 55m
1 stop
JAX
11:28a
DSM
4:26p
4h 58m
1 stop
Depart: Mon Nov 13 2017 Return: Thu Nov 16 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
10:20a
JAX
3:12p
4h 52m
1 stop
JAX
4:07a
DSM
10:42a
6h 35m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

Here's why:

We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

We compile tonnes of data for you
Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
please send us an email and someone from our team will get back to you promptly.

Airports
Origin

Des Moines
$331
Destination

Jacksonville
$331