Find Deals on Flights from Des Moines to Jacksonville (DSM - JAX)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
Students
under 26
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Jacksonville

(Round-trip)
Depart: Mon Feb 13 2017 Return: Wed Feb 15 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
10:20a
JAX
3:46p
5h 26m
1 stop
JAX
2:00a
DSM
8:52a
6h 52m
1 stop
Depart: Sat Feb 11 2017 Return: Tue Feb 14 2017 Trip spans 4 days
Major Airline
Major Airline
DSM
1:00a
JAX
2:01a
1h 01m
nonstop
JAX
1:00a
DSM
4:01a
3h 01m
nonstop
Depart: Thu Feb 16 2017 Return: Wed Feb 22 2017 Trip spans 7 days
United
United
DSM
6:20a
JAX
11:14a
4h 54m
1 stop
JAX
11:36a
DSM
5:08p
5h 32m
1 stop
Depart: Sun Feb 19 2017 Return: Tue Feb 21 2017 Trip spans 3 days
Delta
Delta
DSM
12:11p
JAX
4:35p
4h 24m
1 stop
JAX
12:30p
DSM
6:57p
6h 27m
1 stop
Depart: Tue Feb 14 2017 Return: Wed Feb 22 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
2:00a
JAX
7:16a
5h 16m
1 stop
JAX
3:40a
DSM
10:55a
7h 15m
1 stop
Depart: Sat Feb 18 2017 Return: Wed Feb 22 2017 Trip spans 5 days
United
United
DSM
6:20a
JAX
11:14a
4h 54m
1 stop
JAX
11:36a
DSM
5:08p
5h 32m
1 stop
Depart: Sun Feb 26 2017 Return: Tue Feb 28 2017 Trip spans 3 days
Delta
Delta
DSM
12:11p
JAX
6:42p
6h 31m
1 stop
JAX
1:30a
DSM
7:15a
5h 45m
1 stop
Depart: Wed Feb 15 2017 Return: Wed Feb 22 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
8:23a
JAX
3:46p
7h 23m
1 stop
JAX
5:37a
DSM
10:55a
5h 18m
1 stop
Depart: Tue Feb 21 2017 Return: Thu Feb 23 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
8:23a
JAX
3:51p
7h 28m
1 stop
JAX
5:37a
DSM
10:55a
5h 18m
1 stop
Depart: Fri Feb 3 2017 Return: Tue Feb 14 2017 Trip spans 12 days
Delta
Delta
DSM
6:44a
JAX
11:44a
5h 00m
1 stop
JAX
6:30a
DSM
12:34p
6h 04m
1 stop
Depart: Wed Feb 22 2017 Return: Wed Mar 1 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
10:20a
JAX
3:51p
5h 31m
1 stop
JAX
3:40a
DSM
8:52a
5h 12m
1 stop
Depart: Fri Feb 10 2017 Return: Mon Feb 13 2017 Trip spans 4 days
United
United
DSM
12:00a
JAX
5:04a
5h 04m
1 stop
JAX
11:54a
DSM
5:14p
5h 20m
1 stop
Depart: Sat Feb 4 2017 Return: Sat Feb 11 2017 Trip spans 8 days
Delta
Delta
DSM
12:40a
JAX
5:35a
4h 55m
1 stop
JAX
12:35p
DSM
7:56p
7h 21m
1 stop
Depart: Mon Feb 27 2017 Return: Wed Mar 1 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
10:20a
JAX
5:55p
7h 35m
1 stop
JAX
3:40a
DSM
8:52a
5h 12m
1 stop
Depart: Tue Feb 28 2017 Return: Thu Mar 2 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
8:23a
JAX
3:51p
7h 28m
1 stop
JAX
3:40a
DSM
10:55a
7h 15m
1 stop
Depart: Fri Jun 30 2017 Return: Sat Jul 8 2017 Trip spans 9 days
Delta
Delta
DSM
2:00a
JAX
7:45a
5h 45m
1 stop
JAX
3:30a
DSM
7:56a
4h 26m
1 stop
Depart: Mon Jan 30 2017 Return: Mon Feb 13 2017 Trip spans 15 days
United
United
DSM
9:45a
JAX
4:39p
6h 54m
1 stop
JAX
11:54a
DSM
5:14p
5h 20m
1 stop
Depart: Sat Feb 25 2017 Return: Wed Mar 1 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
11:00a
JAX
3:48p
4h 48m
1 stop
JAX
3:40a
DSM
8:52a
5h 12m
1 stop
Depart: Sat Mar 11 2017 Return: Wed Mar 15 2017 Trip spans 4 days
Major Airline
Major Airline
DSM
12:00a
JAX
1:01a
1h 01m
1 stop
JAX
1:00a
DSM
4:01a
3h 01m
1 stop
Depart: Mon Feb 20 2017 Return: Wed Feb 22 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
9:24a
JAX
5:55p
8h 31m
2 stops
JAX
3:40a
DSM
10:55a
7h 15m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
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Airports
Origin

Des Moines
$331
Destination

Jacksonville
$331