$81 Find Cheap Flights from Des Moines to North Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to North Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh2 stops$237
Charlotte
Charlottenonstop$231
Asheville
Asheville1 stop$249
Wilmington
Wilmington1 stop$268
Greensboro
Greensboro1 stop$294
Fayetteville
Fayetteville2 stops$530
Jacksonville
Jacksonville2 stops$566
Norfolk
Norfolk1 stop$265
Raleigh
Raleigh2 stops$237
Charlotte
Charlottenonstop$231
Asheville
Asheville1 stop$249
Wilmington
Wilmington1 stop$268
Greensboro
Greensboro1 stop$294
Fayetteville
Fayetteville2 stops$530
Jacksonville
Jacksonville2 stops$566
Norfolk
Norfolk1 stop$265

Book Cheap Des Moines to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to North Carolina

Sat, Jan 31 - Sat, Jan 31
American Airlines Logo
5:00 pm - 8:34 pm
DSM
-
CLT
2h 34mnonstop
American Airlines Logo
10:18 pm - 11:12 am
CLT
-
DSM
13h 54m1 stop
$231American Airlines
Tue, Jan 6 - Thu, Jan 8
Multiple Airlines Logo
10:53 am - 12:12 am
DSM
-
RDU
36h 19m2 stops
Multiple Airlines Logo
3:08 pm - 10:46 pm
RDU
-
DSM
8h 38m1 stop
$237Multiple Airlines
Sat, Jan 10 - Tue, Jan 13
Multiple Airlines Logo
5:58 pm - 10:17 am
DSM
-
CLT
15h 19m1 stop
Multiple Airlines Logo
7:43 pm - 5:24 pm
CLT
-
DSM
22h 41m2 stops
$245Multiple Airlines
Fri, Feb 27 - Mon, Mar 2
American Airlines Logo
6:00 am - 2:07 pm
DSM
-
AVL
7h 07m1 stop
American Airlines Logo
2:37 pm - 10:04 pm
AVL
-
DSM
8h 27m1 stop
$249American Airlines
Wed, Mar 18 - Wed, Mar 25
Delta Logo
7:30 am - 4:12 pm
DSM
-
TYS
7h 42m1 stop
Delta Logo
5:30 am - 10:39 am
TYS
-
DSM
6h 09m1 stop
$271Delta
Wed, Jan 7 - Wed, Jan 14
Allegiant Air Logo
6:14 pm - 12:49 pm
DSM
-
TYS
17h 35m1 stop
Allegiant Air Logo
4:47 pm - 10:19 am
TYS
-
DSM
42h 32m2 stops
$285Allegiant Air
Fri, Jan 23 - Mon, Jan 26
Allegiant Air Logo
7:30 am - 10:21 pm
DSM
-
TYS
13h 51m1 stop
Allegiant Air Logo
6:00 am - 1:18 pm
TYS
-
DSM
8h 18m1 stop
$298Allegiant Air
Sat, Feb 21 - Thu, Feb 26
Delta Logo
6:19 am - 12:08 pm
DSM
-
TYS
4h 49m1 stop
Delta Logo
11:48 am - 7:36 pm
TYS
-
DSM
8h 48m1 stop
$300Delta
Tue, Jan 6 - Thu, Jan 8
United Airlines Logo
3:35 pm - 11:44 pm
DSM
-
RDU
7h 09m2 stops
United Airlines Logo
6:18 am - 2:22 pm
RDU
-
DSM
9h 04m2 stops
$300United Airlines
Wed, Jan 7 - Wed, Jan 14
United Airlines Logo
8:00 am - 7:27 pm
DSM
-
TYS
10h 27m2 stops
United Airlines Logo
2:25 pm - 9:50 pm
TYS
-
DSM
8h 25m2 stops
$310United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Des Moines to North Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North Carolina from Des Moines found in the last 72 hours was to Charlotte, at $252 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $252.

Can I save money by flying with a layover from Des Moines to North Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $456 on average.

What is the cheapest month to fly from Des Moines to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to North Carolina is September, when tickets cost $318 (return) on average. On the other hand, the most expensive months are December and January, when the average cost of round-trip tickets is $427 and $406 respectively.

What’s the cheapest day of the week to fly from Des Moines to North Carolina?

The average price of all round-trip flights from Des Moines to North Carolina clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to North Carolina on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Des Moines to North Carolina. For your return ticket, we recommend flying on a Saturday and avoiding Sundays for the best deals.

How far in advance should I book a flight from Des Moines to North Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to North Carolina, you should book around 3 weeks before departure, which saves you about 45% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonNovember
Cheapest flight$87
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Des Moines to Raleigh

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to North Carolina?

    The cheapest time of day to fly to North Carolina is generally in the morning, when round-trip flights cost $352 on average. Morning departures are around 8% cheaper than evening flights, on average. The most expensive time of day to fly to North Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $382.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $233 one-way - $352 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4253 reviews
8.1Boarding
7.0Food
8.6Crew
8.0Comfort
7.5Entertainment
Airline reviews

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

8.0 ExcellentRussell, Dec 2025
SAN - OAK
Read more Southwest reviews

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Still a fan of open seating. Flight was on schedule and arrived on time. The 737 MAX is very comfortable.

Airline travel is always too cramped to really be pleasant, but the cabin crew on this flight did a pretty good job of making up for it by putting on some music during boarding and sprinkling a few funny remarks into the safety briefing and announcements, and just generally being friendly and helpful. It definitely reminded me of why I prefer the in-flight experience on Southwest!

No delays and arrived to destination 30 min early. Staff was super friendly.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

It was rough. The staff was unprofessional, the choice of on board drinks terrible, it was cramped in space at every airport, they always ran out of overhead bin space so they pressured people to check bags for free or we couldn’t leave on the plane— so I did check my bag to help, and they nearly lost my bag. My bag did not arrive on the luggage belt, another man on my flight and I had to waste our time going to the baggage office to search for our bags. I would only fly southwest again if it was my last choice. Also, my flights were consistently delayed over and over again— at one point they straight up told us we were waiting for the pilot to arrive.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

Everything a cheap airline should be at normal airline rates.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

United have really come back. Airport and boarding process is clear and good, app and information also very good

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very bad! They kept delaying my flight and wouldn’t do anything about it

They brought an empty plane to the gate. Then a flight delay was announced for maintenance and waiting on a part. I was then put on a flight to San Francisco instead with a connecting flight to my final destination. Arrived at my final destination 2 hours late.

The only downside was my cell phone charger wouldn’t work in the charging port but everyone else’s would work in them all. My cell phone cable works fine in my hotel room in Frankfurt.

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Ot was overall fine. Left on time and had basic snacks. Weather was finicky but that’s not the airlines fault.

Very thoughtful flight attendant offered me water immediately since I had run to make my connection.

My flight was delayed about three hours. I got home at 3:30 in the morning very bad experience.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

Did not get any refreshments. Crew was very nice but limited. Small seats

The flight was flawless and we even arrived between 20 and 25 minutes early!

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

We had 3 flights. 1 & 2 were on the same plane but we had to de-board just to re-board 30 mins later. That may have been due to a crew change though. Our 3rd flight had a couple “maintenance” issues that held us up. They were quickly resolved but it took forever for someone to bring the paperwork needed so we could leave. Apparently there was a computer glitch so a driver had to bring a physical copy. It delayed us about 1 1/2 hrs. The flights themselves were smooth & no problems. For boarding, I don’t know why they don’t start with the back of the plane & move forward. It would eliminate the back up from people trying to find their seats & put their bags in the overhead bins. Unless you’re on an overseas flight, there is no food, you get a beverage & either a small bag of pretzels or a biscuit cookie. Take your own food or snacks of you want something more.

The actual trip was fine, however, the changes made to our flights and the layovers were had to endure were awful.

Most things were ok but the main problem was the cabin staff; they were very abrupt and not very friendly. They were busy and often rushed, snatching drinks off people before finished and bossing them about.

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports