$86 Find Cheap Flights from Des Moines to North Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to North Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh1 stop$329
Charlotte
Charlotte2 stops$221
Asheville
Asheville1 stop$269
Wilmington
Wilmington1 stop$319
Greensboro
Greensboro1 stop$269
Fayetteville
Fayetteville1 stop$480
Jacksonville
Jacksonville1 stop$527
Norfolk
Norfolk1 stop$381
Raleigh
Raleigh1 stop$329
Charlotte
Charlotte2 stops$221
Asheville
Asheville1 stop$269
Wilmington
Wilmington1 stop$319
Greensboro
Greensboro1 stop$269
Fayetteville
Fayetteville1 stop$480
Jacksonville
Jacksonville1 stop$527
Norfolk
Norfolk1 stop$381

Book Cheap Des Moines to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to North Carolina

Mon, Mar 2 - Thu, Mar 5
Multiple Airlines Logo
8:29 pm - 8:26 am
DSM
-
CLT
34h 57m
2 stops
Multiple Airlines Logo
11:00 am - 10:51 pm
CLT
-
DSM
12h 51m
1 stop
$221Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
Frontier Logo
10:40 am - 7:58 am
DSM
-
CLT
20h 18m
1 stop
Frontier Logo
7:43 pm - 7:16 pm
CLT
-
DSM
24h 33m
1 stop
$229Frontier
Sat, Apr 18 - Sun, Apr 19
American Airlines Logo
8:03 pm - 8:06 am
DSM
-
CLT
11h 03m
1 stop
American Airlines Logo
11:41 am - 1:11 pm
CLT
-
DSM
2h 30mnonstop
$264American Airlines
Tue, Jun 23 - Tue, Jun 30
Delta Logo
6:30 pm - 11:57 pm
DSM
-
GSO
4h 27m
1 stop
Delta Logo
10:45 am - 4:49 pm
GSO
-
DSM
7h 04m
1 stop
$269Delta
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
1:10 pm - 8:50 pm
DSM
-
AVL
6h 40m
1 stop
United Airlines Logo
5:48 pm - 9:27 pm
AVL
-
DSM
4h 39m
1 stop
$269United Airlines
Tue, Mar 10 - Sat, Mar 14
Delta Logo
4:25 pm - 11:03 pm
DSM
-
TYS
5h 38m
1 stop
Delta Logo
5:40 am - 10:48 am
TYS
-
DSM
6h 08m
1 stop
$271Delta
Tue, Feb 17 - Sat, Feb 21
United Airlines Logo
3:24 pm - 8:42 pm
DSM
-
GSO
4h 18m
1 stop
United Airlines Logo
2:47 pm - 9:41 pm
GSO
-
DSM
7h 54m
2 stops
$284United Airlines
Mon, Apr 6 - Mon, Apr 13
American Airlines Logo
5:00 am - 10:55 am
DSM
-
AVL
4h 55m
1 stop
American Airlines Logo
6:00 am - 10:29 am
AVL
-
DSM
5h 29m
1 stop
$289American Airlines
Tue, Apr 28 - Sun, May 3
Southwest Logo
3:15 pm - 8:55 pm
DSM
-
RDU
4h 40m
1 stop
Southwest Logo
8:00 am - 11:30 am
RDU
-
DSM
4h 30m
1 stop
$329Southwest
Tue, Apr 28 - Sun, May 3
Southwest Logo
5:30 am - 4:30 pm
DSM
-
RDU
10h 00m
2 stops
Southwest Logo
8:00 am - 11:30 am
RDU
-
DSM
4h 30m
1 stop
$334Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Des Moines to North Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North Carolina from Des Moines found in the last 72 hours was to Charlotte, at $289 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $289.

Can I save money by flying with a layover from Des Moines to North Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $430, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Des Moines to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to North Carolina is September, when tickets cost $318 (return) on average. On the other hand, the most expensive months are January and December, when the average cost of round-trip tickets is $549 and $421 respectively.

How far in advance should I book a flight from Des Moines to North Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to North Carolina, you should book around 3 weeks before departure, which saves you about 43% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonNovember
Cheapest flight$86
Most popular time to fly and prices are also 10% lower on average.
Flight from Des Moines to Raleigh

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $234 one-way - $380 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4274 reviews
8.0Comfort
8.6Crew
8.1Boarding
7.5Entertainment
7.0Food
Airline reviews

I appreciate the staff who allowed me to board though I arrived a little late! Regarding the assigned seating, I had booked my flight before this change and wasn't aware of the change at the time, and so I didn't select a seat at booking as I didn't realize it was relevant. Better communication about the change would have been helpful for preparing.

10.0 ExcellentMeghan, Feb 2026
MCO - DEN
Read more Southwest reviews

I appreciate the staff who allowed me to board though I arrived a little late! Regarding the assigned seating, I had booked my flight before this change and wasn't aware of the change at the time, and so I didn't select a seat at booking as I didn't realize it was relevant. Better communication about the change would have been helpful for preparing.

Flight attendants very hospitable and friendly. Pilot flew a smooth take off and landing.

Paid for premium extra leg room but the bin space for rows 1-3 had to go in rows 4-6 and 4-6 had to go to 7-9 because flight attendants have snacks and their luggage upfront. So we pay extra to have to fight thru traffic to get our bags. Only 2nd day of new seating so hope they fix this.

WIFI was great. My selection for seating is an aisle, but during my trip, I never had an aisle seat. If we can get that corrected, I will be thrilled. No snack or drink on this flight.

WIFI was great. My selection for seating is an aisle, but during my trip, I never had an aisle seat. If we can get that corrected, I will be thrilled.

The wifi on the plane is great. The only issue that I have is that I prefer an aisle seat and on my trips this week, I was either in the middle or window. If we can work to secure aisle seating, I will be thrilled. Nice trip.

All good except once again bags took an hour at Midway Airport Happens all the time. Ridiculous

Everything went smoothly and we even arrived a little bit early.

Great vacation. Can't wait till next year for another one.

Great flight but super high price. Glad it was a business trip and not personal

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

The attendant on board was amazing. She should be doing business/first international long haul.

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

I would like the crew to talk LESS over the PA and specifically about credit card offers. I am trying to work, sleep, watch a movie and the PA was booming about a credit card offer. Could we go back to the days when the customer was more important than selling a credit card?

It was a good trip. Flight Attendants were friendly and responsive.

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

Tell the crew (when boarding) to yell at the imbeciles blocking us from walking up to scan. I promise everyone crowds around and half of us (most the time I’m group 4) have to push our way through. Your staff is awesome, the public - not so much-

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

Great flight - friendly and attentive team! Seats in coach were comfy, but a little cramped - but that is the case with all airlines ;)

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

My flight was delayed about three hours. I got home at 3:30 in the morning very bad experience.

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports