$119 Find Cheap Flights from Des Moines to North Carolina - Compare and Save

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Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Raleigh
Raleigh1 stop$260
Charlotte
Charlotte2 stops$266
Asheville
Asheville1 stop$285
Wilmington
Wilmington1 stop$397
Greensboro
Greensboro1 stop$319
Fayetteville
Fayetteville1 stop$433
Jacksonville
Jacksonville1 stop$413
Norfolk
Norfolk1 stop$325
Raleigh
Raleigh1 stop$260
Charlotte
Charlotte2 stops$266
Asheville
Asheville1 stop$285
Wilmington
Wilmington1 stop$397
Greensboro
Greensboro1 stop$319
Fayetteville
Fayetteville1 stop$433
Jacksonville
Jacksonville1 stop$413
Norfolk
Norfolk1 stop$325
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to North Carolina?

Flight prices are below average for this route right now.

Flights to North Carolina from Des Moines usually cost between $368 and $576 in September.
The lowest price found in the past 5 days was $266 on Multiple Airlines (Sep 20-Sep 23).

What is the cheapest Des Moines to North Carolina flight route?

The cheapest ticket to North Carolina from Des Moines found in the last 5 days was to Charlotte, at $316 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 5 days was $316.

Can I save money by flying with a layover from Des Moines to North Carolina?

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $475 on average.

What is the cheapest month to fly from Des Moines to North Carolina?

The cheapest month for flights from Des Moines to North Carolina is November, when tickets cost $371 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $580 and $490 respectively.

Good to know

Low season

January

Cheapest flight

$119
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Des Moines to Charlotte

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $268 one-way - $391 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4215 reviews
7.0Food
8.6Crew
8.1Boarding
8.0Comfort
7.5Entertainment
Airline reviews

Seated at front bulkhead for a smidge extra leg room away from home and on flight back home. Away crew was very proactive about assuring our carryons had space close behind us (because no seat in front of us our personal items had to be in a small bin overhead). They actively required passengers place overhead luggage on its side so more items could fit in bins. Home crew made no such efforts. I had to struggle back rows to get overhead bags upon landing, no crew help then either, and some disgruntled passengers as I and others retrieved our bags. There was a system that worked pretty well. The home bound crew just didn't feel like working.

4.0 OkayMather, Aug 2026
Read more Southwest reviews

Seated at front bulkhead for a smidge extra leg room away from home and on flight back home. Away crew was very proactive about assuring our carryons had space close behind us (because no seat in front of us our personal items had to be in a small bin overhead). They actively required passengers place overhead luggage on its side so more items could fit in bins. Home crew made no such efforts. I had to struggle back rows to get overhead bags upon landing, no crew help then either, and some disgruntled passengers as I and others retrieved our bags. There was a system that worked pretty well. The home bound crew just didn't feel like working.

It was good. Last flight was delayed but I always say that is in God's plan

Plane was late. Zero service for 2+ hour flight and it was not that bumpy.

The staff was very friendly, professional, and courteous. The overall flight was a great experience.

southwest just starting charging for luggage. hadnt realized it until it was too late. now out $70 when i couldve bought a carry on if i wouldve known. free bags was one of the only reasons i chose southwest over another airline (the other being no assigned seats, which is apparently also being changed). stupid business decision. wont be flying southwest anymore.

Cluster mess boarding. Can't wait for SWA reserved seating. Internet didn't seem to work on the plane.

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

I liked the boarding by group and numbers. I didn't like my inability to guarantee our seats together. I didn't like the $8/flight for Internet, but I did appreciate the inflight movie options on their app. I didn't like that there were no charging stations on the seats during either of our flights. One flight was over 3 hours.

I never like the fact that if I don't check in exactly 24 hours before the flight time, I get to board C, and that means sitting between 2 individuals. I would like assigned seating in the airplanes.

Flight only half full. Room to spread out. Newer plane. Very satisfied.

I thought the service was very nice and pleasant. There were no hiccups and no issues so overall a good experience.

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

Smooth boarding, pleasant and professional lady checking us in. Crew service was excellent, again pleasant, but professional. Nice touch-down on landing! Thank you Delta. 💗

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

I was exhausted from a long day. The flight was smooth. The first flight during my 3 week travel that took off on time.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

As I wrote earlier, poor planning and/or communication. At least twice, we were told that we would be boarding in less than ten minutes, only to have the flight again delayed at least another hour.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

They promise free wi-fi prior to boarding and then once on board you are informed you have to purchase wifi even after being a mileagePlus member.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

left on time, reasonable boarding process arrived early luggage came out quickly

Very rough getting into denver. my kid threw up it was so rough.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

Luggage handling and communication is extremely poor. I landed in india 15th and recived luggage today. Based on my itag the luggage was in Germany. They kept me in dark. Etihad num er in india was non operatuonal. Had to call USA etihad. It should not be so difficullt. I came for 1 week business trip everything was screwed . This is the first and also will be last for me

I paid extra for a seat up front and at last minute was moved to the 2nd to last row - which I could have had for free. No reason and no refund. Really great customer service American

The first flight was delayed by an hour and a half, so we missed the second flight. They rebooked us on the later flight and I have to sit in the middle for more than 5 hours. Terrible experience. No more American Airlines.

The flight crew was good. I was delayed almost 3 hours and missed my connection, had to rebook and they lost my luggage

Horrible - their gate agents do not care and loyalty means nothing to them. Planes are often late and you are left on your own. Oh, and WiFi - good luck!

It was very hot on the plane and it wasn’t acknowledged by the crew. This whole trip was one of the worst flying experiences I’ve had in a while. We sat in that hot plane on the tarmac in SLC for 45 min (after being delayed for 33 min for crew). 4 hours in the air in a barely cooled cabin. Over 30 min sitting on the tarmac in CLT waiting for a gate. I missed my original connection but was fortunate to get on the last flight out to RDU so I can make my 2 hour drive home. I know these things happen. But it’s frustrating nonetheless.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports