$96 Find Cheap Flights from Des Moines to North Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to North Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh1 stop$231
Charlotte
Charlotte1 stop$240
Asheville
Asheville1 stop$274
Wilmington
Wilmington1 stop$311
Greensboro
Greensboro1 stop$309
Fayetteville
Fayetteville1 stop$419
Jacksonville
Jacksonville1 stop$351
Norfolk
Norfolk2 stops$214
Raleigh
Raleigh1 stop$231
Charlotte
Charlotte1 stop$240
Asheville
Asheville1 stop$274
Wilmington
Wilmington1 stop$311
Greensboro
Greensboro1 stop$309
Fayetteville
Fayetteville1 stop$419
Jacksonville
Jacksonville1 stop$351
Norfolk
Norfolk2 stops$214

Book Cheap Des Moines to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to North Carolina

Mon, Jul 13 - Thu, Jul 16
Allegiant Air Logo
1:37 pm - 10:48 pm
DSM
-
TYS
8h 11m
1 stop
Allegiant Air Logo
3:38 pm - 9:27 pm
TYS
-
DSM
6h 49m
1 stop
$206Allegiant Air
Sun, Jun 28 - Wed, Jul 22
Multiple Airlines Logo
4:01 pm - 11:26 am
DSM
-
ORF
42h 25m
2 stops
Multiple Airlines Logo
7:06 pm - 11:07 pm
ORF
-
DSM
29h 01m
1 stop
$214Multiple Airlines
Mon, Jul 13 - Thu, Jul 16
Allegiant Air Logo
5:30 pm - 3:30 pm
DSM
-
TYS
21h 00m
2 stops
Allegiant Air Logo
3:38 pm - 9:27 pm
TYS
-
DSM
6h 49m
1 stop
$220Allegiant Air
Wed, Jun 10 - Wed, Jun 10
American Airlines Logo
9:23 am - 8:50 pm
DSM
-
CLT
10h 27m
1 stop
American Airlines Logo
10:45 pm - 12:12 am
CLT
-
DSM
2h 27mnonstop
$267American Airlines
Wed, Jul 1 - Wed, Jul 8
American Airlines Logo
4:48 pm - 11:09 pm
DSM
-
AVL
5h 21m
1 stop
American Airlines Logo
5:31 pm - 11:58 pm
AVL
-
DSM
7h 27m
1 stop
$274American Airlines
Wed, Jun 10 - Wed, Jun 17
Delta Logo
5:35 am - 11:09 am
DSM
-
TYS
4h 34m
1 stop
Delta Logo
8:35 am - 1:35 pm
TYS
-
DSM
6h 00m
1 stop
$307Delta
Tue, Jun 23 - Tue, Jun 30
Delta Logo
5:35 am - 11:38 am
DSM
-
GSO
5h 03m
1 stop
Delta Logo
4:35 pm - 10:31 pm
GSO
-
DSM
6h 56m
1 stop
$309Delta
Wed, Jun 24 - Wed, Jul 1
United Airlines Logo
11:26 am - 11:50 pm
DSM
-
ILM
11h 24m
2 stops
United Airlines Logo
3:42 pm - 10:51 pm
ILM
-
DSM
8h 09m
1 stop
$365United Airlines
Tue, Jul 7 - Wed, Jul 8
Southwest Logo
5:20 am - 6:25 pm
DSM
-
MYR
12h 05m
2 stops
Southwest Logo
2:10 pm - 10:45 pm
MYR
-
DSM
9h 35m
2 stops
$367Southwest
Sat, Sep 12 - Wed, Sep 23
Southwest Logo
5:30 am - 3:40 pm
DSM
-
MYR
9h 10m
2 stops
Southwest Logo
2:25 pm - 9:55 pm
MYR
-
DSM
8h 30m
2 stops
$374Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to North Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to North Carolina departing in June.

What is the cheapest Des Moines to North Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North Carolina from Des Moines found in the last 7 days was to Charlotte, at $321 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 7 days was $321.

Can I save money by flying with a layover from Des Moines to North Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $463 on average.

What is the cheapest month to fly from Des Moines to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to North Carolina is March, when tickets cost $155 (return) on average. On the other hand, the most expensive months are December and January, when the average cost of round-trip tickets is $309 and $299 respectively.

Good to know

Low seasonJanuary
Cheapest flight$96
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Des Moines to Charlotte

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $177 one-way - $409 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4280 reviews
8.0Comfort
7.0Food
8.1Boarding
8.6Crew
7.5Entertainment
Airline reviews

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

4.0 OkayAnonymous, May 2026
MDW - LAX
Read more Southwest reviews

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

The flight was smooth. The Southwest experience has degraded overall, but this one was okay.

No gluten free snacks. Seats felt worn or bare bones even though it was a new 737 MAX 8.

One major problem that was very unprofessional and uncalled for. Plane landed and we had to wait 20 minutes to get off the plane since they were waiting for someone to come to the gate to drive the jetway. Southwest couldn't have someone available and waiting for the plane to land? Is there only one person in Hobby airport who knows to drive the jetway? Was he at lunch? In the bar? Uncomfortable and uncalled for!

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

I'm glad it wasn't only 75% full because I could get a good seat

if I was good. Not happy that I have to pay extra money to get the seat I need for lake room, but I guess that’s a sign of the times.

Seats were very comfortable. They tilted back. Drinks and snacks were free and served 3 times. Attendants were awesome.

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

Truly terrible. Will never willingly fly southwest again. Seats are worse than before they switched to assigned seating. One flight attendant was the opposite of helpful (rude, unhelpful, dismissive, and as my stranger seatmate said unprompted: a total prick). This caused me, 15 minutes into the flight, to book an alternate return flight home on a competing airline (first class 1.2k purchase instead of my existing planned flight) just so I would not have to ever be on that aircraft, with that terrible service person, with those horrific seats ever again.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

We had a delay, but thankfully I made it to my connection. Overall it went smooth

The flight had a delay but I made it to my connection. Flight was smooth overall

As I wrote earlier, poor planning and/or communication. At least twice, we were told that we would be boarding in less than ten minutes, only to have the flight again delayed at least another hour.

This flight is a quick way to get to Chicago, but a bit expensive.

Our flight to Rome, Italy was cancelled the day of and we were never informed. We only found out because I was trying to get into my husbands account and called to get his account number. Had to pay more for worse seating on another airline.

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

First class ticket gets you no seat back entertainment? I have to bring my own laptop to see a movie? And most of their movies have ADS? No thank you. Worse: Tiny snacks only on a 2 hr flight?

Late- that’s what United does best. Missed my connection, rebooked to a flight 17 hours later and had to spend $500 on a hotel. What did I get? A $15 meal voucher. What can you get in an airport for $15. I hate United so much.

Late plane. Only one crew on the ground so we b had to wait for Denver flight to come in, board, and depart. At 78 yrs of age I was not pleased trying to get my connection. What really made me angry was the notification you sent me to hurry up or I would miss my connection. Why tell me to hurry up when you got me in late. It was not a good way of treating customers.

No complaints other than luggage carousel was incorrectly guiding passengers to the wrong carousel on the screen.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

We had several flights and they were all on-time and flawless

The small flights with Valet Luggage has a poor service

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

Delayed flight. Missed connection, AA put us on a later connecting flight. The connection flight was delayed 4 times and we had to deplane. Didnt get home until 3am, when I was supposed to be home at 8:30p. Zero compensation offered from American. I would not fly them again.

No gate in Rome. Had stairs. Got separated from my wife in a wheel chair. Customs was a zoo. If AA doesnt have landing rights, it should be advertised.

The captain announced to the cabin there would be a delay because they observed a "cut" on a tire during precheck that needed to be cleared by maintenance. We were delayed during this inspection and allowed to proceed after maintenance "measured the cut and decided it was acceptable". My complaint is not about the delay or due diligence. I wish the captain had been more generic when making his announcement. I was a nervous wreck all the way to Charlotte worried that we would have a blowout when landing!

Flight was delayed and they gave up my seat on my connection, even when I could still make the flight

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports