$104 Find Cheap Flights from Des Moines to North Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to North Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh1 stop$258
Charlotte
Charlotte2 stops$290
Asheville
Asheville1 stop$224
Wilmington
Wilmington1 stop$311
Greensboro
Greensboro2 stops$319
Fayetteville
Fayetteville1 stop$379
Jacksonville
Jacksonville1 stop$403
Norfolk
Norfolk1 stop$256
Raleigh
Raleigh1 stop$258
Charlotte
Charlotte2 stops$290
Asheville
Asheville1 stop$224
Wilmington
Wilmington1 stop$311
Greensboro
Greensboro2 stops$319
Fayetteville
Fayetteville1 stop$379
Jacksonville
Jacksonville1 stop$403
Norfolk
Norfolk1 stop$256

Book Cheap Des Moines to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to North Carolina

Thu, Jul 16 - Sun, Jul 19
Allegiant Air Logo
5:08 pm - 10:00 pm
DSM
-
TYS
27h 52m
1 stop
Allegiant Air Logo
3:38 pm - 10:47 pm
TYS
-
DSM
8h 09m
1 stop
$213Allegiant Air
Mon, Jul 13 - Thu, Jul 23
Allegiant Air Logo
4:40 pm - 10:30 am
DSM
-
AVL
16h 50m
1 stop
Allegiant Air Logo
6:30 am - 4:40 pm
AVL
-
DSM
35h 10m
2 stops
$224Allegiant Air
Sat, Oct 24 - Wed, Oct 28
Delta Logo
11:04 am - 7:02 pm
DSM
-
AVL
6h 58m
1 stop
Delta Logo
5:40 am - 10:18 am
AVL
-
DSM
5h 38m
1 stop
$275Delta
Tue, Jul 21 - Tue, Jul 28
American Airlines Logo
7:04 am - 12:34 pm
DSM
-
TYS
4h 30m
1 stop
American Airlines Logo
6:10 pm - 12:09 am
TYS
-
DSM
6h 59m
1 stop
$279American Airlines
Tue, Jul 21 - Tue, Jul 28
United Airlines Logo
6:00 am - 2:27 pm
DSM
-
TYS
7h 27m
2 stops
United Airlines Logo
5:45 pm - 10:56 pm
TYS
-
DSM
6h 11m
1 stop
$284United Airlines
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
5:20 am - 5:00 pm
DSM
-
TYS
10h 40m
2 stops
Southwest Logo
12:45 pm - 10:50 pm
TYS
-
DSM
11h 05m
2 stops
$289Southwest
Sat, Sep 5 - Tue, Sep 8
American Airlines Logo
9:32 am - 4:44 pm
DSM
-
AVL
6h 12m
1 stop
American Airlines Logo
5:34 pm - 11:25 pm
AVL
-
DSM
6h 51m
1 stop
$292American Airlines
Wed, Aug 12 - Mon, Aug 17
United Airlines Logo
6:00 am - 2:37 pm
DSM
-
TYS
7h 37m
2 stops
United Airlines Logo
7:00 am - 10:26 am
TYS
-
DSM
4h 26m
1 stop
$304United Airlines
Fri, Jul 3 - Sat, Jul 4
Delta Logo
11:42 am - 7:55 pm
DSM
-
TYS
7h 13m
1 stop
Delta Logo
6:45 am - 10:14 am
TYS
-
DSM
4h 29m
1 stop
$307Delta
Wed, Jul 22 - Wed, Jul 29
Southwest Logo
3:45 pm - 9:50 pm
DSM
-
MYR
5h 05m
1 stop
Southwest Logo
2:10 pm - 10:50 pm
MYR
-
DSM
9h 40m
2 stops
$322Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to North Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to North Carolina departing in July.

What is the cheapest Des Moines to North Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North Carolina from Des Moines found in the last 5 days was to Charlotte, at $343 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 5 days was $343.

Can I save money by flying with a layover from Des Moines to North Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $476 on average.

What is the cheapest month to fly from Des Moines to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to North Carolina is March, when tickets cost $155 (return) on average. On the other hand, the most expensive months are December and January, when the average cost of round-trip tickets is $309 and $299 respectively.

Good to know

Low seasonJanuary
Cheapest flight$104
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Des Moines to Charlotte

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $261 one-way - $426 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4242 reviews
8.0Comfort
7.5Entertainment
8.6Crew
7.0Food
8.1Boarding
Airline reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

2.0 MediocreIrene, Jun 2026
DEN - SFO
Read more Southwest reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

Crew was rude, flight was late, wifi didn't work, no food, basically nothing about this flight was good.

It was just okay, no frills, basic transportation with no luxury. No screens on the seats, no water or drinks on a short flight. Full flight but at least it was on time.

Flight was constantly delayed with significant changes in time, it was supposed to get to Colorado Springs at 8:30 PM but it got there after midnight.

Over a 3 hour flight. The turbulence was almost imperceptible except for 2 short periods which were not bad and over quickly. The attendants claimed "Safety first" and sat looking at their phones for 3 hours with no drink or snack service. This isn't the first time with Southwest. I thinkit may be there new plan of operation. Oh, and it was June 18, Southwest's Birthday which offered free drinks. NOT.

Flight was delayed, full flight and I had to change gates. Southwest flights are always late later in the day.

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

It was great. The gate staff were very helpful in Portland when my son forgot his rolling bag and had to go back to get it just in time to make it on the plane. We really appreciate that. Great job!

Airline is not very senior friendly. Flights are late, forcing us to run to the connecting flight. Food is awful. Wish they would go back to pretzels and peanuts. During flight, pressurization isn’t quite right and all of our ears get plugged. Everything is nickel and dime, charging for boarding, seat selection and legroom. While a screen at the desk in the gate area says check your roll on bag now for free due to space limitation, the employee at the desk will not check the bag without a $100 fee. Insane.

Kayak could’ve posted the correct gate number. Almost missed my flight.

Love me some Delta. One of the few airlines to recognize and support veterans. Easy boarding, flight was on time and arrived early and the flight attendants were excellent on this flight.

I thought the service was very nice and pleasant. There were no hiccups and no issues so overall a good experience.

Very good flight. Crew was great. No issues and we even arrived early.

The flights are constantly late anymore, and they won't even give you a glass of water on the plane. For years, they were able to do a service on this flight from Atlanta to Knoxville and Knoxville Atlanta now they say it's too short of a flight. You can't even get a quick drink of water.

Flight got canceled 4 times, missed my connecting flight due to delays, have to wait to go home tomorrow

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Great experience nice pilot very soft and easy landing and take off

We sat on the runway for over an hour before departure. That was unwelcome.

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

Great experience. Boarding was fast, staff were very nice and funny, everything at the seat worked well.

Boarding was great, and the crew were very friendly. The seats must have been a bit on the older side and you could feel some of the seat components through the padding. Also, the plugs did not work on the row's entertainment screen or charging ports. Checked bag was transferred for connecting flight, and we appreciated how early we had the connecting gate information.

Lost one piece of luggage even though I checked in 2.5 hours before the flight

For the expense of first class, the seats could have been nicer and higher tier snacks would have been nice.

The boarding process on the departure from LA was rather slow even though I was in Group 1. For first class, I was not expecting to have to pay for Wi-fi but I did and then the wi-fi was spotty. The entree was surprisingly good and so that was a pleasant surprise. However, once I got to Houston, it was terrible. Unfortunately there was bad weather but the constant gate changes for my connecting flight was difficult to manage due to having to navigate back and forth between different terminals.

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

Very easy ! Use the kiosk and bag drop and right to security within 10 min

Checking bag at terminal was horrible. No agents to check us in and only 1 kiosk working. Boarding went ok. Crew onboard was very scattered rained. Missed our row while serving and then didn’t see them hardly again.

Crew was amazing, takeoff wonderful. The bathroom was disgusting from before takeoff the odor made the flight uncomfortable as you could smell the bathroom from the center of the plane where we were sitting. Smelled like raw sewage. My daughter was throwing up as we landed due to the smell and horrible turbulence as we approached Newark.

Airline tickets are not cheap. You expect reliable competent service. Thanks to canceled flights and botched transfers we arrived at our destination two days late. This is not acceptable

I was not clear if food was offered or not.

They did not offer coffee on a 7am flight…awful!!

Check in for 5am flight at RDU was hampered by American check in counters being seriously understaffed , was told even supervisor called out. Took so long in line for special services check in that we missed our 5am departure even after arriving at 3:30am. Had to be rescheduled to later flight from Charlotte to St Thomas.

The Charleston, WV airport was cute. Very good staff and small enough to feel comfortable. The plane had more leg room than bigger planes. Much more comfortable.

Take-off delayed an hour because of a missing flight officer, so,arrived in Charlotte lates causing many passengers to miss connections. Otherwise a very good flight, safe and comfortable, with an excellent professional crew.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

We had several flights and they were all on-time and flawless

The small flights with Valet Luggage has a poor service

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports