$99 Find Cheap Flights from Des Moines to North Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to North Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh1 stop$219
Charlotte
Charlotte1 stop$220
Asheville
Asheville2 stops$254
Wilmington
Wilmington1 stop$311
Greensboro
Greensboro1 stop$311
Fayetteville
Fayetteville2 stops$432
Jacksonville
Jacksonville2 stops$428
Norfolk
Norfolk1 stop$275
Raleigh
Raleigh1 stop$219
Charlotte
Charlotte1 stop$220
Asheville
Asheville2 stops$254
Wilmington
Wilmington1 stop$311
Greensboro
Greensboro1 stop$311
Fayetteville
Fayetteville2 stops$432
Jacksonville
Jacksonville2 stops$428
Norfolk
Norfolk1 stop$275

Book Cheap Des Moines to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to North Carolina

Cmt, May 16 - Per, May 21
Allegiant Air Logo
11:00 am - 6:03 pm
DSM
-
TYS
6h 03m
1 stop
Allegiant Air Logo
1:03 pm - 10:31 pm
TYS
-
DSM
10h 28m
1 stop
$216Allegiant Air
Çar, May 27 - Cum, May 29
Multiple Airlines Logo
2:16 pm - 11:31 am
DSM
-
RDU
20h 15m
1 stop
Multiple Airlines Logo
11:47 am - 11:24 pm
RDU
-
DSM
12h 37m
1 stop
$219Multiple Airlines
Çar, May 27 - Per, Haz 4
Delta Logo
5:27 am - 11:09 am
DSM
-
TYS
4h 42m
1 stop
Delta Logo
1:59 pm - 5:53 pm
TYS
-
DSM
4h 54m
1 stop
$226Delta
Sal, May 19 - Çar, May 20
Delta Logo
6:41 pm - 11:56 pm
DSM
-
TYS
4h 15m
1 stop
Delta Logo
5:40 am - 11:08 am
TYS
-
DSM
6h 28m
1 stop
$253Delta
Çar, May 27 - Per, Haz 4
United Airlines Logo
3:01 pm - 11:12 pm
DSM
-
TYS
7h 11m
1 stop
United Airlines Logo
6:30 am - 10:27 am
TYS
-
DSM
4h 57m
1 stop
$259United Airlines
Cmt, Eyl 5 - Sal, Eyl 8
American Airlines Logo
6:00 am - 2:53 pm
DSM
-
AVL
7h 53m
1 stop
American Airlines Logo
6:45 pm - 11:26 pm
AVL
-
DSM
5h 41m
1 stop
$290American Airlines
Sal, Eyl 15 - Pzt, Eyl 21
United Airlines Logo
5:50 am - 3:13 pm
DSM
-
ORF
8h 23m
1 stop
United Airlines Logo
6:30 am - 10:11 am
ORF
-
DSM
4h 41m
1 stop
$290United Airlines
Cmt, Eyl 5 - Çar, Eyl 9
Southwest Logo
5:30 am - 11:05 am
DSM
-
MYR
4h 35m
1 stop
Southwest Logo
7:50 am - 11:50 am
MYR
-
DSM
5h 00m
1 stop
$290Southwest
Cum, Tem 3 - Sal, Tem 7
American Airlines Logo
1:39 pm - 12:15 am
DSM
-
AVL
9h 36m
2 stops
American Airlines Logo
5:34 pm - 12:29 am
AVL
-
DSM
7h 55m
1 stop
$295American Airlines
Sal, Eyl 15 - Pzt, Eyl 21
Southwest Logo
6:10 am - 3:55 pm
DSM
-
ORF
8h 45m
2 stops
Southwest Logo
8:00 am - 11:25 am
ORF
-
DSM
4h 25m
1 stop
$296Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to North Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to North Carolina departing in June.

What is the cheapest Des Moines to North Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North Carolina from Des Moines found in the last 72 hours was to Charlotte, at $331 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $331.

Can I save money by flying with a layover from Des Moines to North Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $443, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Des Moines to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to North Carolina is March, when tickets cost $155 (return) on average. On the other hand, the most expensive months are December and January, when the average cost of round-trip tickets is $309 and $299 respectively.

Good to know

Low seasonJanuary
Cheapest flight$99
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Des Moines to Raleigh

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $214 one-way - $427 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4324 reviews
7.5Entertainment
7.0Food
8.1Boarding
8.0Comfort
8.6Crew
Airline reviews

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

4.0 OkayCrystal, Apr 2026
MSY - MDW
Read more Southwest reviews

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

First time I've had to use the disabled accommodations. And I could not have had a better experience with Southwest, i was having trouble getting from one terminal to another due to my heart failure. And the next thing I know a Southwest agent had made sure. I had a wheelchair at all my flights. Can't thank them enough.

Delayed flight, lack of information, boarding process is a mess as is the carryon luggage causing issues when leaving the plane….just a poor experience.

Comfortable. Easy. No problems. Just wish they had gf options for snacks.

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

We waited in the airplane for over 45 min for a southwest employee to make the flight. This cause over half the plane to miss their connecting flight in Denver. When we confronted the desk upon arrival, they told us the only flight they had was the next day leaving at 8:50 pm!!! Or they offered to get us to Burbank or LA, but after that we were on our own to get back to Santa Barbara. I paid for a flight from sba to bna bna to sba. My re entry into mom mode has been 💯 rough because of southwest mistake with my flight. And now I’m leaving to Reno tomorrow for a vballl tournament and just discovered that my leg in Vegas has me and my 3 kids on a stand by flight even though I had booked these ticket last year November!! Do better southwest!

Southwest is kind of a slum airline. It’s gotten more expensive over the years for less and less service. I am a Southwest Chase Visa card holder and was forced to choose a seat in the 26th row in the middle seat. However my wife who is a rewards member but doesn’t hold a card or anything else, gets randomly assigned a normally paid seat in row 6! How does that work?

For the first time in a long time, the Wi-Fi actually worked the entire flight! The flight crew was amazing as usual.

The seat was not comfortable. 1D. My back was sore all night and the next day.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

They told us yesterday APR21st that they were cleaning the plane and we got delayed. After that they said they didn't had any crew for the flight so they cancelled the flight till next day.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight crew on this leg of my trip was very friendly and pleasant. Every one of them was humorous, as well as helpful and accommodating. This group was BY FAR the best crew I’ve flown with. They deserve kudos.

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

Delayed flight. Missed connection, AA put us on a later connecting flight. The connection flight was delayed 4 times and we had to deplane. Didnt get home until 3am, when I was supposed to be home at 8:30p. Zero compensation offered from American. I would not fly them again.

No gate in Rome. Had stairs. Got separated from my wife in a wheel chair. Customs was a zoo. If AA doesnt have landing rights, it should be advertised.

The captain announced to the cabin there would be a delay because they observed a "cut" on a tire during precheck that needed to be cleared by maintenance. We were delayed during this inspection and allowed to proceed after maintenance "measured the cut and decided it was acceptable". My complaint is not about the delay or due diligence. I wish the captain had been more generic when making his announcement. I was a nervous wreck all the way to Charlotte worried that we would have a blowout when landing!

Flight was delayed and they gave up my seat on my connection, even when I could still make the flight

Flight was delayed. No urgency by American Airlines team to assist those with connecting flights. It was basically you are on your own to run through the terminals to try and make your connection. Thanks, Mary

I have never been assaulted they way I was today in Charlotte - shame on American

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports