$76 Find Cheap Flights from Des Moines to North Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to North Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to North Carolina, as well as popular online travel agencies
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Cheap Flights from Des Moines to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh1 stop$240
Charlotte
Charlotte1 stop$192
Asheville
Asheville1 stop$309
Wilmington
Wilmington1 stop$310
Greensboro
Greensboro1 stop$310
Fayetteville
Fayetteville1 stop$409
Jacksonville
Jacksonville1 stop$492
Norfolk
Norfolk1 stop$263
Raleigh
Raleigh1 stop$240
Charlotte
Charlotte1 stop$192
Asheville
Asheville1 stop$309
Wilmington
Wilmington1 stop$310
Greensboro
Greensboro1 stop$310
Fayetteville
Fayetteville1 stop$409
Jacksonville
Jacksonville1 stop$492
Norfolk
Norfolk1 stop$263

Book Cheap Des Moines to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to North Carolina

Fri, May 1 - Tue, May 5
Frontier Logo
2:04 pm - 4:56 pm
DSM
-
CLT
25h 52m
1 stop
Frontier Logo
5:20 pm - 1:31 pm
CLT
-
DSM
21h 11m
1 stop
$192Frontier
Mon, May 11 - Wed, May 13
Multiple Airlines Logo
2:16 pm - 4:25 pm
DSM
-
CLT
25h 09m
1 stop
Multiple Airlines Logo
6:41 pm - 3:15 pm
CLT
-
DSM
21h 34m
1 stop
$230Multiple Airlines
Sat, May 2 - Tue, May 5
American Airlines Logo
5:00 am - 12:30 pm
DSM
-
TYS
6h 30m
1 stop
American Airlines Logo
5:00 am - 11:30 am
TYS
-
DSM
7h 30m
2 stops
$231American Airlines
Wed, Apr 22 - Mon, Apr 27
American Airlines Logo
7:11 am - 4:55 pm
DSM
-
RDU
8h 44m
1 stop
American Airlines Logo
6:28 pm - 10:18 pm
RDU
-
DSM
4h 50m
1 stop
$260American Airlines
Wed, Apr 15 - Wed, Apr 22
Delta Logo
5:45 pm - 10:55 pm
DSM
-
ORF
4h 10m
1 stop
Delta Logo
5:50 am - 11:05 am
ORF
-
DSM
6h 15m
1 stop
$263Delta
Mon, Apr 20 - Wed, Apr 22
United Airlines Logo
3:21 pm - 11:44 pm
DSM
-
RDU
7h 23m
2 stops
United Airlines Logo
5:25 pm - 11:17 pm
RDU
-
DSM
6h 52m
1 stop
$265United Airlines
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
3:15 pm - 8:55 pm
DSM
-
CLT
4h 40m
1 stop
Southwest Logo
6:20 pm - 10:10 pm
CLT
-
DSM
4h 50m
1 stop
$283Southwest
Wed, Apr 15 - Wed, Apr 22
Delta Logo
6:10 am - 11:55 am
DSM
-
MYR
4h 45m
1 stop
Delta Logo
3:57 pm - 9:12 pm
MYR
-
DSM
6h 15m
1 stop
$287Delta
Wed, May 6 - Sat, May 9
United Airlines Logo
7:05 pm - 12:59 am
DSM
-
ORF
4h 54m
1 stop
United Airlines Logo
5:14 pm - 9:25 pm
ORF
-
DSM
5h 11m
1 stop
$290United Airlines
Wed, Jun 10 - Mon, Jun 15
Southwest Logo
5:20 am - 10:45 am
DSM
-
ORF
4h 25m
1 stop
Southwest Logo
7:15 pm - 11:30 pm
ORF
-
DSM
5h 15m
1 stop
$335Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to North Carolina flights

Get data-powered insights and trends into flights from Des Moines to North Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to North Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to North Carolina departing in May.

What is the cheapest Des Moines to North Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North Carolina from Des Moines found in the last 72 hours was to Charlotte, at $316 round-trip. The most popular route is from Des Moines (DSM) to Charlotte (CLT), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $316.

Can I save money by flying with a layover from Des Moines to North Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $430, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Des Moines to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to North Carolina is September, when tickets cost $318 (return) on average. On the other hand, the most expensive months are December and November, when the average cost of round-trip tickets is $421 and $406 respectively.

Good to know

Low seasonJanuary
Cheapest flight$76
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 15% lower on average.
Flight from Des Moines to Raleigh

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Des Moines to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Charlotte $242 one-way - $388 round-trip

Reviews of the top 4 airlines serving from Des Moines to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4333 reviews
8.1Boarding
8.0Comfort
7.5Entertainment
8.6Crew
7.0Food
Airline reviews

Southwest continues to do less for more money. Flight attendants used to be fun and friendly. But now it’s like they don’t even see you. Such a shame.

6.0 GoodDavid, Mar 2026
RSW - BWI
Read more Southwest reviews

Southwest continues to do less for more money. Flight attendants used to be fun and friendly. But now it’s like they don’t even see you. Such a shame.

Great flight. Good snacks and drinks. Grateful it was free. The flight from Nashville to louisville, i think her name was Tracy (not sure that's right) super awesome, nice and cheerful. She really enjoyed being at work today! She was the person who scanned the boarding pass on flight wn941. She should be recommended for a raise !

I liked it better when you were truer to your roots Am paying more for less fun

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

Boarding was easy. The seats are small and fairly uncomfortable

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

We had a 5 hour delay on the tarmac in Baltimore

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

I am still at the Airport! Delayed Delayed and Delyaed

I took seat 15A in anticipation of window seat, there is no window.

The first class flight attendant was awful to everyone. Very rude; no customer service. She should not be working in first class.

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

It was fine. 55 minute flight. No snacks or beverage service offered. Boarding went smoothly and my walker was waiting for me on the jet way.

Smaller plane for a longer flight than my first one. Doesn’t make sense.

The cabin temperature was nice and cool. The wifi was not working.

They promise free wi-fi prior to boarding and then once on board you are informed you have to purchase wifi even after being a mileagePlus member.

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

Awful. No counter attendants. No dinner offered due to delays.

Horrible service no Wi-Fi connection on both leg of the flight and they are refusing to fix bad service

3 hour delay…. Nearly 2 hours sitting on tarmac. Do better, United. Or at least have the sense to not say “we hope you enjoyed your flight with us” upon disembarking.

Flights were on time. Free Wifi on plane. Everything was well organized.

During landing. 2 crew members passed 3 times by my lane and didn't notice that people in front of us had their site to the furthermore reclined... That was uncomfortable and could have been dangerous.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

We had excellent customer service despite the chaos at George Bush airport in Houston!

It isvvery small flight. No leg room . No space to put my personal item at feet.

My flight from LGA was cancelled and my rebooked flight from JFK was delayed numerous times. I will now be getting home after 2am.

I appreciate that I finally got the seat I paid extra for this time. Thank you

It would have been nice if American tried to care.

I booked 1st class, my flights were changed and I was sitting in the middle at the back of the plane. A far cry from the 1st class I purchased for my flights. I am grateful I arrived on time.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Flights were constantly delayed. CRW took 50 minutes to get bags

The flight was delayed multiple times. I was autobooted and placed in the center seat in the last row of the plane.

My flight was delayed. We left at midnight. I got to Greensboro (GSO) at 1am. All of AA's flights in/out of Charlotte always seem to be delayed or canceled. It took me all day on Sunday to get to my destination of Cincinnati from Greensboro. I had to be rerouted through Chicago because my original flight was canceled as the door to plane was closing in GSO. The saddest part is I could have driven and arrived sooner. . . I recognize there is a lot going on that impacts travel. This week it was weather. Yesterday in Cincinnati it was President Trump. But as a frequent flyer, the flight from South Bend to Charlotte always runs late. The subsequent flight to Greensboro is always midnight to 2am. . . I do want to give props the Charlotte boarding crew. They had four flights going out of the same area at the same time. They turned it quickly and mitigated the grumbling from the crowd.

Never had such a lazy first class attendant. Literally spent 60%+ of the flight playing games on her personal phone making up excuses of why she was unavailable.

The baggage claim experience was poor. The plane crew and the AA app said that checked baggage in CLT would be at carousel 7 but the sign at Baggage Claim said carousel 1. The carousel 1 sign had the correct flight # listed above the belt. But the luggage never came. I went to an AA baggage claim office after about 1 hour and the clerk directed me to another AA room that was poorly marked, with a closed door and no obvious way to know what to do. Finally someone opened the door and my bag was inside. The clerk was totally unable to explain why.

Everything you need to know for your flight from Des Moines to North Carolina

Information on your arrival and departure airports