DSM - SNA

$100 Find Cheap Flights from Des Moines to John Wayne (Santa Ana)

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santa Ana departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to John Wayne (Santa Ana)

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to John Wayne (Santa Ana), as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to John Wayne (Santa Ana), as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$191
Typical prices: $188-$124
Allegiant Air
Thu 9/17Thu 9/24
DSM - SNA • Non-stop
Cheapest non-stop
$217
Typical prices: $268-$186
Allegiant Air
Sun 5/24Sun 5/31
DSM - SNA • Non-stop
Nonstop flights
Mon, Thu, Fri, Sat, Sun
You can fly direct with Allegiant Air. Average duration is 3h 46m
Direct flights
Direct flights
+1
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Direct flights
Direct flights
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Top airlines
Cheapest • from $191 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
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When to book
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 26% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 50% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Ana!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santa Ana (DSM-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santa Ana

Thu, Sep 17 - Thu, Sep 24
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
$191Allegiant Air
Thu, Sep 17 - Thu, Sep 24
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
$201Allegiant Air
Sun, May 24 - Sun, May 31
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
$217Allegiant Air
Thu, Sep 17 - Sun, Sep 20
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
$225Allegiant Air
Sun, Jul 12 - Sun, Jul 19
Allegiant Air Logo
7:00 am - 8:33 am
DSM
-
SNA
3h 33mnonstop
Allegiant Air Logo
9:23 am - 2:42 pm
SNA
-
DSM
3h 19mnonstop
$232Allegiant Air
Thu, Sep 17 - Sun, Sep 20
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
$235Allegiant Air
Thu, Sep 17 - Sun, Sep 20
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
$237Allegiant Air
Mon, May 11 - Sun, May 24
Allegiant Air Logo
10:00 am - 11:51 am
DSM
-
SNA
3h 51mnonstop
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
$239Allegiant Air
Mon, May 11 - Sun, May 24
Multiple Airlines Logo
3:46 pm - 10:08 pm
DSM
-
SNA
8h 22m
1 stop
Multiple Airlines Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
$241Multiple Airlines
Mon, Jul 27 - Thu, Jul 30
Multiple Airlines Logo
10:01 pm - 3:23 pm
DSM
-
SNA
19h 22m
1 stop
Multiple Airlines Logo
9:23 am - 2:42 pm
SNA
-
DSM
3h 19mnonstop
$242Multiple Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santa Ana flights

Get data-powered insights and trends into flights from Des Moines to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Santa Ana, California?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Santa Ana, California departing in September.

What’s the cheapest day of the week to fly from Des Moines to John Wayne (Santa Ana)?

The average price of all round-trip flights from Des Moines to Santa Ana clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to John Wayne (Santa Ana) on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Des Moines to John Wayne (Santa Ana). For your return ticket, we recommend flying on a Monday and avoiding Tuesdays for the best deals.

What is the cheapest month to fly from Des Moines to John Wayne (Santa Ana)?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Santa Ana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to John Wayne (Santa Ana) is January, where tickets cost $158 (return) on average. On the other hand, the most expensive months are March and November, where the average cost of round-trip tickets is $569 and $397 respectively.

How far in advance should I book a flight from Des Moines to John Wayne (Santa Ana)?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Santa Ana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to John Wayne (Santa Ana), you should book around 4 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonJuly
Cheapest flight$100
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly and prices are also 50% lower on average.
Flight from Des Moines to John Wayne (Santa Ana)

When to book flights from Des Moines to Santa Ana

Are your dates flexible? Find out the best times to travel from Des Moines to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to John Wayne (Santa Ana)

  • What is the cheapest flight from Des Moines to John Wayne (Santa Ana)?

    In the last 3 days, the lowest price for a flight from Des Moines to John Wayne (Santa Ana) was $100 for a one-way ticket and $191 for a round-trip.

  • Do I need a passport to fly between Des Moines and John Wayne (Santa Ana)?

    No

  • Which airports will I be using when flying from Des Moines to John Wayne (Santa Ana)?

    Des Moines and John Wayne (Santa Ana) are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Santa Ana J. Wayne/Orange Cnty.

  • Which airlines offer Wi-Fi service onboard planes from Des Moines to John Wayne (Santa Ana)?

    American Airlines, and Delta offer inflight Wi-Fi service on the Des Moines to John Wayne (Santa Ana) flight route.

  • Which aircraft models fly most regularly from Des Moines to John Wayne (Santa Ana)?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Des Moines to John Wayne (Santa Ana) flight route.

  • Which airline alliances offer flights from Des Moines to John Wayne (Santa Ana)?

    Star Alliance, and oneworld are the airline alliances operating flights between Des Moines and John Wayne (Santa Ana), with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Des Moines to John Wayne (Santa Ana)?

    You can catch a nonstop flight from Des Moines to John Wayne (Santa Ana) on on Monday, Thursday, Friday, and Sunday.

  • Which is the best airline for flights from Des Moines to John Wayne (Santa Ana), Southwest or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to John Wayne (Santa Ana) are Southwest and United Airlines. With an average price for the route of $476 and an overall rating of 8.0, Southwest is the most popular choice. United Airlines is also a great choice for the route, with an average price of $432 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Des Moines to John Wayne (Santa Ana)

  • Looking for a cheap flight? 25% of our users found flights on this route for $73 or less one-way and $216 or less round-trip.

Prefer to fly direct from Des Moines to John Wayne (Santa Ana)?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Find which airlines fly direct from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport, which days they fly and book direct flights.

Direct departures

Des Moines to Santa Ana J. Wayne/Orange Cnty

Monday

Allegiant Air

Allegiant Air

Thursday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Saturday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Santa Ana J. Wayne/Orange Cnty to Des Moines

Monday

Allegiant Air

Allegiant Air

Thursday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Saturday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 4 airlines serving from Des Moines to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to John Wayne (Santa Ana). Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4315 reviews
8.1Boarding
8.0Comfort
8.6Crew
7.0Food
7.5Entertainment
Airline reviews

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

8.0 ExcellentCheryl, Apr 2026
DEN - SBA
Read more Southwest reviews

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

The Air hostess were very rude on my flight from Houston to Austin . Their regular communication itself felt a they are shouting at people.

Boarding was easy. The seats are small and fairly uncomfortable

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

Mediocre. Boarding is now unpleasant. The employees, once friendly and nice, are now regularly speaking sternly to passengers, badgering them to do things right so they can take off on time and gate check bags because they don't have enough overhead bin space. The pretzel snack was crushed flat and broken into even smaller pieces, which happens frequently lately. Drink service was suspended before they reached my row.

The charges were ridiculous for an hour flight and the turbulence was very scary.

3 hour delay. Had to change plans and was still delayed.

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Packed in plane small uncomfortable seats elbow to elbow nobody wants to be in that situation for the money they paid

Checking in united could not figure out my star alliance gold. Baggage did not get marked priority and didn't receive boarding passes. When got to SFO lounge personal fixed everything Immediately

Flight left on time, arrived early, pleasant staff provided water, coffee, etc. access to bathrooms was reasonable and were well maintained. blankets were available, lots of entertainment options. LUGGAGE SERVICE WAS GREAT. I got my one checked bag quickly and was able to make a bus connection for a 2 hour bus ride saving me from waiting another 1.5 hours.

Terrible, if possible won't be flying again anytime soon!

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

Horrible service no Wi-Fi connection on both leg of the flight and they are refusing to fix bad service

Great. No choice for n/a. No food or entertainment options

No food is available without purchasing it and there is no in-flight entertainment. Both of these are OK because we got an inexpensive flight from Allegiant and, otherwise, our experience was excellent.

just had water and there was plenty of leg & seat room. But then i don't weight 220#s!!

Not totally their fault- screaming kids that had zero parent intervention.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

I had a fantastic experience with Allegiant. I had wheelchair assistance and they helped me find my luggage and brought me to my car. Even loaded my luggage. Wonderful service!! Thank you Allegiant!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

There is not one likable thing about this airline. It’s starts with the deceptive pricing and continues through the whole flight. The worst staff I’ve ever experienced way over priced bags absolutely no food or drink (unacceptable and you should be embarrassed) the seats are cramped and uncomfortable there is no entertainment there is nothing about this trash airline that constitutes any amount of money. It’s worse than spirit and way more expensive it is disgraceful. Do not travel with Allegiant I repeat do not bother no matter what they say the price is it is never ever going to be the right choice I’m mind blown at how awful the entire experience was I’m embarrassed that I chose so poorly I cannot reiterate enough how beyond horrible this company and its staff are, not one person on this flight or at the airport is qualified to sweep up trash on a city sidewalk they should certainly never be given any job that requires a brain or manners or communication with human beings, what a disgrace to the human race. Your criminal chiselers and should be put out to pasture

Great flight. Friendly staff. Free snacks and drinks would be nice. I would love fewer taxes and fees added on.

My 90 year old father flew with me. He needed wheel chair assistance and is nearly deaf. The staff was amazing with him.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

To have arrived on time and not 3 hours late after having already spent $100 to change to an earlier flight, only to arrive back home close to the original flight time.

American Airlines is a miserable experience. It is predictably miserable, in the sense that every time I fly American, I brace myself for the certainty that it will be unpleasant and uncomfortable. But it is unpredictable in the sense that I never know if the flight will be on time or delayed nine hours (both happened to me this week). I never know if I will be able to sit in the seat that I selected when I purchased the ticket or if I will be told by Customer Service (!!!) that I must relocate from first class to a seat in the back of the aircraft with no explanation (both happened to me this week). Will the food be frozen and half defrosted, or scalding hot? Will the drinks be warm? Will the flight attendants be surly and mean? Will the toilets be cramped and foul? Will the seats be narrow and uncomfortable? Will there be a real electric outlet at the seat, or just an unreliable USB-2 port? Will there be enough seats in the boarding lounge or just a few? Will the boarding process be smooth and efficient, or will the gate agents mess it up and delay it needlessly for 30 or 40 minutes? Will the catering and cleaning crew be prompt or will they take an extra 30 minutes? Will the brakes on the aircraft work properly, or will the pilot delay takeoff for four hours while the ground crew attends to what can only be described as routine maintenance that should have been done the night before? I've eexperienced every one of these unpleasant things this year, 2026. The only thing I can reliably count on is that American will find a new way to make the experience of flying as miserable as they possibly can.

Wifi was spotty. Tray table was very dirty when I sat down.

The WiFi would not connect enough for me to do my actual work. It permaspooled, disconnected, said it was connected, then wouldn't open an email... it was frustrating. I am not a tall person, 5'4" - and I felt cramped with little room to reach into my bag under the seat in front of me. I feel sorry for anyone taller than me having to fly. the one positive thing I will add, is the overhead bins are roomy enough to manage more bags than other carriers.

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

Delayed for mechanical and no updates on what was happening and how long the delay might be.

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Everything you need to know for your flight from Des Moines to Santa Ana

Information on your arrival and departure airports