DSM - SNA

$64 Find Cheap Flights from Des Moines to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santa Ana departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santa Ana, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Des Moines to Santa Ana (DSM-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santa Ana

Sun, Sep 14 - Sun, Sep 21
Allegiant Air Logo
8:00 am - 9:43 amDSM-SNA
3h 43mnonstop
Allegiant Air Logo
10:33 am - 3:48 pmSNA-DSM
3h 15mnonstop
$108Allegiant Air
Find Deal
Thu, Sep 4 - Sun, Sep 14
Allegiant Air Logo
8:00 am - 9:43 amDSM-SNA
3h 43mnonstop
Allegiant Air Logo
10:33 am - 3:48 pmSNA-DSM
3h 15mnonstop
$149Allegiant Air
Find Deal
Thu, Aug 28 - Thu, Sep 4
 Logo
2:14 pm - 9:21 pmDSM-SNA
9h 07m1 stop
 Logo
10:33 am - 3:48 pmSNA-DSM
3h 15mnonstop
Sun, Sep 14 - Sun, Sep 21
 Logo
3:42 pm - 10:05 pmDSM-SNA
8h 23m1 stop
 Logo
10:33 am - 3:48 pmSNA-DSM
3h 15mnonstop
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
5:10 am - 9:32 amDSM-SNA
6h 22m1 stop
American Airlines Logo
11:35 am - 8:21 pmSNA-DSM
6h 46m1 stop
$295American Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
5:10 am - 10:52 amDSM-SNA
7h 42m1 stop
American Airlines Logo
12:47 pm - 11:13 pmSNA-DSM
8h 26m1 stop
$296American Airlines
Find Deal
Sat, Nov 1 - Wed, Nov 5
United Airlines Logo
2:52 pm - 9:54 pmDSM-SNA
9h 02m1 stop
United Airlines Logo
12:15 pm - 10:20 pmSNA-DSM
8h 05m1 stop
$297United Airlines
Find Deal
Sat, Nov 1 - Wed, Nov 5
United Airlines Logo
1:35 pm - 8:42 pmDSM-SNA
9h 07m2 stops
United Airlines Logo
7:00 am - 4:12 pmSNA-DSM
7h 12m1 stop
$302United Airlines
Find Deal
Tue, Aug 19 - Mon, Aug 25
Southwest Logo
6:30 am - 11:20 amDSM-SNA
6h 50m2 stops
Southwest Logo
7:50 am - 4:45 pmSNA-DSM
6h 55m1 stop
$317Southwest
Find Deal
Mon, Jan 26 - Wed, Feb 4
Southwest Logo
6:10 am - 1:50 pmDSM-SNA
9h 40m2 stops
Southwest Logo
7:15 am - 7:20 pmSNA-DSM
10h 05m2 stops
$327Southwest
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to Santa Ana flights

Get data-powered insights and trends into flights from Des Moines to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to John Wayne (Santa Ana)?

The average price of all round-trip flights from Des Moines to Santa Ana clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to John Wayne (Santa Ana) on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Monday is the most expensive day to fly from Des Moines to John Wayne (Santa Ana). For your return ticket, we recommend flying on a Wednesday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from Des Moines to Santa Ana?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Santa Ana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Santa Ana is September, where tickets cost $132 (return) on average. On the other hand, the most expensive months are November and March, where the average cost of round-trip tickets is $436 and $406 respectively.

Can I save money by flying with a layover from Des Moines to Santa Ana?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $286, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Des Moines to Santa Ana?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Santa Ana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Santa Ana, you should book around 3 weeks before departure, which saves you about 32% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonJuly
Cheapest flight$64
Best time to beat the crowds but there is an average 31% increase in price.
Most popular time to fly with an average 41% increase in price.
Flight from Des Moines to John Wayne (Santa Ana)

When to book flights from Des Moines to Santa Ana

Are your dates flexible? Find out the best times to travel from Des Moines to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to John Wayne (Santa Ana)

  • What is the cheapest flight from Des Moines to Santa Ana?

    In the last 3 days, the lowest price for a flight from Des Moines to Santa Ana was $64 for a one-way ticket and $108 for a round-trip.

  • Do I need a passport to fly between Des Moines and John Wayne (Santa Ana)?

    No

  • Which airports will I be using when flying from Des Moines to John Wayne (Santa Ana)?

    Des Moines and John Wayne (Santa Ana) are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Santa Ana J. Wayne/Orange Cnty.

  • Which airlines offer Wi-Fi service onboard planes from Des Moines to John Wayne (Santa Ana)?

    American Airlines, and Delta offer inflight Wi-Fi service on the Des Moines to John Wayne (Santa Ana) flight route.

  • Which aircraft models fly most regularly from Des Moines to John Wayne (Santa Ana)?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Des Moines to John Wayne (Santa Ana) flight route.

  • On which days can I fly direct from Des Moines to John Wayne (Santa Ana)?

    You can catch a nonstop flight from Des Moines to John Wayne (Santa Ana) on on Thursday, and Sunday.

  • Which is the best airline for flights from Des Moines to Santa Ana, Southwest or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santa Ana are Southwest and United Airlines. With an average price for the route of $506 and an overall rating of 8.0, Southwest is the most popular choice. United Airlines is also a great choice for the route, with an average price of $472 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Des Moines to Santa Ana

  • Looking for a cheap flight? 25% of our users found flights on this route for $100 or less one-way and $121 or less round-trip.

Prefer to fly direct from Des Moines to John Wayne (Santa Ana)?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Find which airlines fly direct from Des Moines Airport to Santa Ana J. Wayne/Orange Cnty Airport, which days they fly and book direct flights.

Direct departures

Des Moines to Santa Ana J. Wayne/Orange Cnty

Thursday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Santa Ana J. Wayne/Orange Cnty to Des Moines

Thursday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 4 airlines serving from Des Moines to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4241 reviews
8.0Comfort
8.1Boarding
8.6Crew
7.5Entertainment
7.0Food
Airline reviews

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

10.0 ExcellentGordon, Jul 2025GEG - OAK
Read more Southwest reviews

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

First time traveling on Southwest since bag fees were implemented. Usual good service. Just more expensive now.

It was a perfect flight in all aspects! Both legs!

Boarding process, crew were good. But the seats were so uncomfortable that was all I could focus on. I literally had to sit forward so that all 3 of us could fit in row. I will try to avoid Southwest in the future for any flights over 60 minutes.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

Great experience flying Southwest. The crew was really kind and helpful, and very friendly with our toddler.

Plane late from DC to Austin 30 minutes. Crew made up much of the time enroute to San Diego.

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

I will be flying again Southwest Airlines. Friendly crew, comfortable and affordable.

Boarded plane and then delayed 1.5 hours while on the plane

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

Very rough getting into denver. my kid threw up it was so rough.

We were given vouchers we couldn’t use with a 5.5 hour delay

Really good 😊 the woman at the gate entrance was a little rude checking in our carry-on but i dont think she worked for the airline, she worked for the airport at sacramento, other than that amazing.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

United out of SFO is having issues with catering so none of our meals were loaded on the plane and no offer of compensation for our tickets purchased was offered.

A bit rush for transit. Food and entertainment are not available

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

In flight connectivity (via T-Mobile) was often not working.

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

Everything you need to know for your flight from Des Moines to Santa Ana

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