$84 Find Cheap Flights from Des Moines to John Wayne (Santa Ana) - Compare and Save

Only Allegiant Air operates flights between Des Moines and Santa Ana.

Flights from Des Moines to Santa Ana usually depart from Des Moines (DSM) and arrive at Santa Ana J. Wayne/Orange Cnty (SNA).

Two cabin classes are available on flights from Des Moines to Santa Ana:

• Economy Class
• First Class

On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $226 round-trip, compared to $472 via a layover through Denver Intl (DEN).

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $38–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A320-100/200 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Embraer 175 variants.

One-stop flights from Des Moines to Santa Ana most commonly connect through:

• Denver Intl (DEN) - 46% of one-stop connections
• Phoenix Sky Harbor Intl (PHX) - 39% of one-stop connections
• Las Vegas Harry Reid Intl (LAS) - 8% of one-stop connections
• Dallas/Fort Worth (DFW) - 6% of one-stop connections

Denver Intl (DEN) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 54% on the Des Moines to Santa Ana route. Monday is the cheapest departure day at $202 round-trip on average, while Saturday is the most expensive at $433, a difference of $231. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Some of the most popular sights in Santa Ana are Embassy Suites by Hilton Santa Ana Orange County Airport, Westfield Mainplace and Santa Ana Zoo. These are among the most viewed places in Santa Ana on KAYAK.

These are the earliest and latest flight times available from Des Moines to Santa Ana:

• Earliest: departs at 7:00 am and lands at 10:39 am
• Latest: departs at 2:50 pm and lands at 6:29 pm.

The flight takes about 3h 39m.

Last-minute fares on this route - booked within 2 weeks of departure - run 55% above the route average of $300. Book 22 weeks before departure for the lowest fares.

A nonstop flight from Des Moines to Santa Ana takes 3h 39m, covering 1,425 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

One-way fares from Des Moines to Santa Ana are currently lower than usual. Average one-way flight prices are about $160, which is 18% below the typical average for this route.

Flying via Denver Intl (DEN) gives the shortest average 1-stop total travel time at 5h 33m, compared with 5h 42m via Phoenix Sky Harbor Intl (PHX) and 6h 12m via Las Vegas Harry Reid Intl (LAS).

Santa Ana is 2 hours behind Des Moines (Pacific Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Santa Ana J. Wayne/Orange Cnty Airport (SNA) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include:
· Thrifty
· Dollar
· Budget
· Alamo
· GREEN MOTION

Round-trip flights from Des Moines to Santa Ana range from $210 to $434, with an average of $300 over the past 12 months. Anything below $210 counts as a good deal.