$94 Find Cheap Flights from John Wayne (Santa Ana) to Des Moines - Compare and Save

These are the earliest and latest flight times available from Santa Ana to Des Moines:

• Earliest: departs at 10:10 am and lands at 1:29 pm
• Latest: departs at 5:33 pm and lands at 8:52 pm.

The flight takes about 3h 19m.

Two cabin classes are available on flights from Santa Ana to Des Moines:

• Economy Class
• First Class

A nonstop flight from Santa Ana to Des Moines takes 3h 19m, covering 1,425 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Round-trip flights from Santa Ana to Des Moines range from $196 to $427, with an average of $287 over the past 12 months. Anything below $196 counts as a good deal.

On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $205 round-trip, compared to $260 via a layover through Dallas/Fort Worth (DFW).

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A320-100/200 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Embraer 175 variants.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $225 to $1,373. That means the highest observed fare was about 6x higher than the lowest one.

One-way fares from Santa Ana to Des Moines are currently lower than usual. Average one-way flight prices are about $139, which is 34% below the typical average for this route.

Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:

• Hertz
• Payless
• Budget
• Alamo
• Avis

Flights from Santa Ana to Des Moines usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Des Moines (DSM).

One-stop flights from Santa Ana to Des Moines most commonly connect through:

• Denver Intl (DEN) - 51% of one-stop connections
• Phoenix Sky Harbor Intl (PHX) - 38% of one-stop connections
• Las Vegas Harry Reid Intl (LAS) - 6% of one-stop connections
• Dallas/Fort Worth (DFW) - 2% of one-stop connections

Yes. Flexible dates can save you up to 59% on flights from Santa Ana to Des Moines. Thursday is the cheapest departure day at $236 round-trip on average, while Saturday is the most expensive at $565, a difference of $329.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Allegiant Air operates flights between Santa Ana and Des Moines.

Flying via Phoenix Sky Harbor Intl (PHX) gives the shortest average 1-stop total travel time at 5h 46m, compared with 5h 47m via Denver Intl (DEN) and 5h 56m via Minneapolis St Paul (MSP).

Des Moines is 2 hours ahead of Santa Ana (Central Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in Des Moines are UnityPoint Health - Des Moines, Science Center of Iowa and Hy Vee Hall. These are among the most viewed places in Des Moines on KAYAK.