SNA - DSM

$75 Find Cheap Flights from Santa Ana to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Des Moines departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Des Moines, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santa Ana to Des Moines (SNA-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Des Moines

Thu, Nov 13 - Sun, Nov 16
Allegiant Air Logo
11:37 am - 4:59 pmSNA-DSM
3h 22mnonstop
Allegiant Air Logo
9:00 am - 10:47 amDSM-SNA
3h 47mnonstop
$135Allegiant Air
Find Deal
Thu, Nov 13 - Mon, Nov 17
Multiple Airlines Logo
11:37 am - 4:59 pmSNA-DSM
3h 22mnonstop
Multiple Airlines Logo
2:32 pm - 1:30 pmDSM-SNA
24h 58m1 stop
$153Multiple Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Frontier Logo
12:01 pm - 1:49 pmSNA-DSM
23h 48m1 stop
Frontier Logo
2:32 pm - 1:30 pmDSM-SNA
24h 58m1 stop
$159Frontier
Find Deal
Thu, Nov 13 - Sun, Nov 16
Multiple Airlines Logo
6:45 am - 9:12 pmSNA-DSM
12h 27m1 stop
Multiple Airlines Logo
9:00 am - 10:47 amDSM-SNA
3h 47mnonstop
$201Multiple Airlines
Find Deal
Thu, Feb 12 - Sun, Feb 15
American Airlines Logo
9:47 am - 5:35 pmSNA-DSM
5h 48m1 stop
American Airlines Logo
5:15 am - 8:57 amDSM-SNA
5h 42m1 stop
$306American Airlines
Find Deal
Thu, Feb 12 - Sun, Feb 15
American Airlines Logo
9:47 am - 5:35 pmSNA-DSM
5h 48m1 stop
American Airlines Logo
5:15 am - 8:57 amDSM-SNA
5h 42m1 stop
$316American Airlines
Find Deal
Thu, Feb 12 - Sun, Feb 15
United Airlines Logo
11:10 am - 8:41 pmSNA-DSM
7h 31m1 stop
United Airlines Logo
3:24 pm - 10:08 pmDSM-SNA
8h 44m2 stops
$402United Airlines
Find Deal
Thu, Feb 12 - Sun, Feb 15
United Airlines Logo
11:10 am - 9:51 pmSNA-DSM
8h 41m2 stops
United Airlines Logo
3:24 pm - 10:08 pmDSM-SNA
8h 44m2 stops
$407United Airlines
Find Deal
Sun, Dec 21 - Wed, Dec 24
Southwest Logo
12:10 pm - 11:10 pmSNA-DSM
9h 00m2 stops
Southwest Logo
8:20 am - 2:30 pmDSM-SNA
8h 10m2 stops
$462Southwest
Find Deal
Sun, Dec 21 - Tue, Dec 23
Southwest Logo
12:10 pm - 11:10 pmSNA-DSM
9h 00m2 stops
Southwest Logo
6:35 am - 12:20 pmDSM-SNA
7h 45m2 stops
$493Southwest
Find Deal

Everything you should know

Top airlines
Allegiant Air
Cheapest • from $135 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
February
Cheapest • 62% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
5 days a week
There are direct flights from Santa Ana to Des Moines 5 days a week: Tue, Thu, Fri, Sat, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Cheapest round-trip
$135
Overall average: $293
Allegiant Air
Thu 11/13Sun 11/16
SNA - DSM • Non-stop
Cheapest one-way
$75
Typical prices: $164-$293
Frontier
Thu 11/13
SNA - DSM • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Booking Insights

KAYAK's insights & trends for Santa Ana to Des Moines flights

Get data-powered insights and trends into flights from Santa Ana to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from John Wayne (Santa Ana) to Des Moines?

The average price of all round-trip flights from Santa Ana to Des Moines clicked on KAYAK for each day over the last 12 months.

For John Wayne (Santa Ana) to Des Moines, Wednesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Des Moines back to John Wayne (Santa Ana), the best deals are generally found on Sunday, with Tuesday being the most expensive.

What is the cheapest month to fly from Santa Ana to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Des Moines is February, where tickets cost $125 (return) on average. On the other hand, the most expensive months are June and July, where the average cost of round-trip tickets is $436 and $436 respectively.

Can I save money by flying with a layover from Santa Ana to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $300, prices are generally cheapest when you fly direct.

Good to know

Low seasonFebruary
Cheapest flight$75
Best time to beat the crowds with an average 63% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from John Wayne (Santa Ana) to Des Moines

When to book flights from Santa Ana to Des Moines

Are your dates flexible? Find out the best times to travel from Santa Ana to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Des Moines

  • What is the cheapest flight from Santa Ana to Des Moines?

    In the last 3 days, the lowest price for a flight from Santa Ana to Des Moines was $75 for a one-way ticket and $135 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Des Moines?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airlines offer Wi-Fi service onboard planes from John Wayne (Santa Ana) to Des Moines?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the John Wayne (Santa Ana) to Des Moines flight route.

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Des Moines?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the John Wayne (Santa Ana) to Des Moines flight route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Des Moines?

    Star Alliance, and oneworld are the airline alliances operating flights between John Wayne (Santa Ana) and Des Moines, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from John Wayne (Santa Ana) to Des Moines?

    You can catch a nonstop flight from John Wayne (Santa Ana) to Des Moines on on Monday, Tuesday, Thursday, Saturday, and Sunday.

  • Which is the best airline for flights from Santa Ana to Des Moines, Southwest or United Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Ana to Des Moines are Southwest and United Airlines. With an average price for the route of $446 and an overall rating of 8.0, Southwest is the most popular choice. United Airlines is also a great choice for the route, with an average price of $698 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from John Wayne (Santa Ana) to Des Moines?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santa Ana J. Wayne/Orange Cnty to Des Moines.
Find which airlines fly direct from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Santa Ana J. Wayne/Orange Cnty to Des Moines

Tuesday

Allegiant Air

Allegiant Air

Thursday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Saturday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Des Moines to Santa Ana J. Wayne/Orange Cnty

Tuesday

Allegiant Air

Allegiant Air

Thursday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Saturday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 4 airlines serving from Santa Ana to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4242 reviews
8.0Comfort
7.5Entertainment
7.0Food
8.1Boarding
8.6Crew
Airline reviews

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

8.0 ExcellentGreg, Oct 2025OAK - BUR
Read more Southwest reviews

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Sacrament staff are always polite and helpful. Airport is easy to maneuver and boarding is straightforward.

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

The weather could have been better. There was a 40 minute ATC delay in SFO because of marine fog and a micro cell storm delayed landing and take-off at Nashville. The gate was changed 5 minutes from boarding from gate B3 to gate C23 at Nashville airport.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

Delayed flight. Nicest crew member was a SW pilot flying seated next to me who kindly move to seat the final passenger. Flight extra delayed. My cup of refreshment of ginger ale was so packed with ice it was literally 2 sips.

No trays in our seats, we sat in first row, purchased a business class fare. Had to hold our drinks and snack in our hands. No plugs for our cell phones. Had to pay for it a drink cocktail each. Seats so uncomfortable.

Flight wasn’t even full, but too many carry-ons caused us to run out of bin space. New bag fee has folks who would usually check their bags carrying on. Watching Southwest morph into Spirit/Frontier is so sad to watch

Southwest is Southwest. No frills. If you're luck enough to get a happy crew (we did), then it makes for a nicer flight.

It was a perfect flight in all aspects! Both legs!

The flight attendants were great, I joked with one I can’t remember her name, a blond, really sweet. I thought it was run well very professional. This was great i survived Spirit, I know for which I speak.

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

I understand stuff happens, but plane failures are likely due to lack of maintenance. Additionally, air conditioning wasn't working, no snack/drink service, no WiFi. Fortunately, the crew was communicative and light-hearted. United grabbed another plane and we were able to get to our destination.

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

It was great, I’m very grateful for the pilots and crew flight attendants for everything.

Everything was great. Only thing that could’ve made it better was buy on board options for hot food, but the snacks were decent. The flight attendants were great. I had no complaints. I was able to make it to my destination safely

Boarded plane and then delayed 1.5 hours while on the plane

The flight was flawless and we even arrived between 20 and 25 minutes early!

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

Very crowded flight but what can you expect these days?? Crew was accommodating.

The seats in economy were appeared to be quite thin and lack sufficient cushioning to be comfortable. Perhaps it was my seating position but the plane seemed notably load.

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

Everything you need to know for your flight from Santa Ana to Des Moines

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