$93 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Detroit to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$485
Bogotá
Bogotá1 stop$358
Sao Paulo
Sao Paulo3 stops$702
Santiago
Santiago2 stops$752
Cartagena
Cartagena2 stops$359
Quito
Quito2 stops$516
Guayaquil
Guayaquil2 stops$482
Cali
Cali2 stops$534
Cusco
Cusco3 stops$554
Barranquilla
Barranquilla2 stops$437
Montevideo
Montevideo3 stops$922
Lima
Lima2 stops$485
Bogotá
Bogotá1 stop$358
Sao Paulo
Sao Paulo3 stops$702
Santiago
Santiago2 stops$752
Cartagena
Cartagena2 stops$359
Quito
Quito2 stops$516
Guayaquil
Guayaquil2 stops$482
Cali
Cali2 stops$534
Cusco
Cusco3 stops$554
Barranquilla
Barranquilla2 stops$437
Montevideo
Montevideo3 stops$922

Book Cheap Detroit to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South America

Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
6:50 pm - 1:22 pm
DTW
-
MDE
19h 32m
1 stop
Multiple Airlines Logo
2:06 pm - 12:46 am
MDE
-
DTW
9h 40m
1 stop
$326Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
Spirit Airlines Logo
4:17 pm - 12:21 am
DTW
-
MDE
9h 04m
1 stop
Spirit Airlines Logo
1:17 am - 3:12 pm
MDE
-
DTW
12h 55m
1 stop
$344Spirit Airlines
Fri, Apr 17 - Sat, May 2
Multiple Airlines Logo
3:57 pm - 1:12 pm
DTW
-
BOG
22h 15m
1 stop
Multiple Airlines Logo
2:07 pm - 9:10 am
BOG
-
DTW
42h 03m
2 stops
$358Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Spirit Airlines Logo
8:15 am - 12:21 am
DTW
-
MDE
17h 06m
1 stop
Spirit Airlines Logo
2:06 pm - 5:18 pm
MDE
-
DTW
26h 12m
2 stops
$358Spirit Airlines
Tue, May 12 - Tue, May 19
Air Canada Logo
10:15 am - 9:50 am
DTW
-
GRU
22h 35m
1 stop
Air Canada Logo
9:35 pm - 10:08 am
GRU
-
DTW
13h 33m
1 stop
$816Air Canada
Mon, Aug 31 - Mon, Sep 21
GOL Logo
6:19 am - 10:45 am
DTW
-
GIG
27h 26m
2 stops
GOL Logo
10:30 pm - 10:52 pm
GIG
-
DTW
25h 22m
2 stops
$933GOL
Tue, Sep 1 - Wed, Sep 23
Air Canada Logo
10:15 am - 2:30 pm
DTW
-
EZE
27h 15m
2 stops
Air Canada Logo
4:35 pm - 9:29 pm
EZE
-
DTW
29h 54m
2 stops
$951Air Canada
Tue, Sep 1 - Wed, Sep 23
Azul Logo
10:15 am - 2:30 pm
DTW
-
EZE
27h 15m
2 stops
Azul Logo
4:35 pm - 10:07 am
EZE
-
DTW
18h 32m
1 stop
$981Azul
Wed, May 20 - Wed, Jun 3
Azul Logo
10:15 am - 2:30 pm
DTW
-
EZE
27h 15m
2 stops
Azul Logo
4:35 pm - 9:25 pm
EZE
-
DTW
53h 50m
2 stops
$984Azul
Thu, Sep 3 - Sun, Sep 27
GOL Logo
6:19 am - 4:40 pm
DTW
-
SDU
33h 21m
2 stops
GOL Logo
6:00 am - 10:52 pm
SDU
-
DTW
17h 52m
2 stops
$1,016GOL
Booking Insights

KAYAK's insights & trends for Detroit to South America flights

Get data-powered insights and trends into flights from Detroit to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South America is February, when tickets cost $504 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $1,093 and $1,030 respectively.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 5 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$93
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Detroit to South America

 
Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8366 reviews
8.5Crew
7.2Food
7.8Entertainment
7.9Comfort
8.1Boarding
Airline reviews

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

10.0 ExcellentAnonymous, Apr 2026
MIA - DTW
Read more Delta reviews

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

During the flight, the only refreshments provided were crackers and soft drinks; no substantial food was offered despite the international route. Furthermore, our initial flight was delayed, causing us to miss the connecting flight in Atlanta. The airline did not hold the connection, and we were informed that the next available flight is not for another 24 hours. While I am aware of alternative options via JetBlue, they operate out of JFK, which is not a viable solution for us as a resident of New Jersey.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

Delta is always a wonderful experience. A clean plane and the crew is really friendly.

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Flight was delayed. No urgency by American Airlines team to assist those with connecting flights. It was basically you are on your own to run through the terminals to try and make your connection. Thanks, Mary

I have never been assaulted they way I was today in Charlotte - shame on American

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

Better snacks but flight and crew were amazing on this flight

Found that the plane used for this short flight is smaller and therefore the seats are really squeezed tight.

It was the most un-special flight experience in my life.

Plane was super cold. No entertainment unless you were with mileage program Getting off the plane was super slow

Flight was on-time, boarding was flawless and the crew was friendly.

The staff are very, very professional. It's what flying should feel like.

Flight boarded from Gate 159B, the farthest gate in the LAX Bradley Terminal. While the flight operated on time, the first class cabin attendant made no recognition of my being an Advantage Executive Platinum member.

I bought a ticket from Kayak. When I got to the airport, the was no ticket. I had to pay 5X to get to my destination. No response received from Kayak. I will NEVER use them again.

My wallet was stolen while I was sleeping on the plane.

Good boarding but extremely cold temperature in both flights (60 F!).

The whole plane smelled and felt old. The seats were very uncomfortable. Multiple delays. Extra fees.

Very rude gate attendants in San Francisco who didn’t let me bring my little carry on (smaller than usual size) and after boarding I realized that there still were a lot of overhead compartment space (like a full section available in some spots). That made me lose 30 minutes at my destination at 1am and it could have broken something fragile that I had in it

The most uncomfortable flight I’ve ever been on. I’m only 5,4” and barely had enough room to exist, couldn’t even fully relax my shoulders. Not sure why they bother with snacks. Half a coke and a single cookie?? Wow. Purchasable food looked gross too. Remember when airlines used to treat you like a human being?

Departed Palm Springs over an hour late because there’s only one gate, and it has always delayed by the arriving and departing flight to Toronto and the arriving flight from Vancouver.

I checked a bag and there was only one agent to assist all customers with any issues.

I want to thank Carlos at the Miami AC desk - he was amazing and went over and above to help us out. Thank you Carlos and all the best to you!!! You made our faith in AC feel great! Sincerely, David Cubitt

Flight was canceled due to mechanical issues. After a considerable wait in the queue, Air Canada customer service was very helpful to get us on another flight. I am disappointed to report our rescheduled flight is for three days from now. Three days of extra expenses and inconvenience is unacceptable.

The ticket price are reasonable, however, they can do better with the price on the luggage. Overall, I will continue using spirit.

That this is my second time the they cancel flights and they always wait until the last minute to let people know

The flight was supposed to leave at 6:22pm we are just now leaving the gate after deplaning twice at 1:07am.

Spirit is always late. Every single time. Always a different reason

They keep delaying and cancel at last moment and height was for you to get refund need to be in chat line for two hours. I complained to DOT. Never recommend this airline on Kayak please

First flight in along time with spirit! I’m honored to say this flight was excellent 😊

Spirit is awful. Do not fly spirit. Nothing but delays, cancellations.

Every connection was late but that meant I was not running from one to the next so that was a good thing. No one wants to miss a connection

Food and entertainment see irrelevant to rate them as that’s not really an option anymore. The flight was fast and friendly. The plane was immaculately clean.

Flight was delayed more than 3 hours, and the metro had stopped running by the time we got to the terminal well past midnight, so I was stranded, alone, with no way to get home until the metro started up the next morning.

Everything you need to know for your flight to South America

Information on your arrival and departure airports