$166 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Detroit to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$560
Bogotá
Bogotá1 stop$585
Sao Paulo
Sao Paulo3 stops$761
Santiago
Santiago3 stops$877
Cartagena
Cartagena1 stop$348
Quito
Quito1 stop$619
Guayaquil
Guayaquil2 stops$632
Cali
Cali1 stop$618
Cusco
Cusco2 stops$1,053
Barranquilla
Barranquilla1 stop$611
Montevideo
Montevideo2 stops$1,191
Lima
Lima2 stops$560
Bogotá
Bogotá1 stop$585
Sao Paulo
Sao Paulo3 stops$761
Santiago
Santiago3 stops$877
Cartagena
Cartagena1 stop$348
Quito
Quito1 stop$619
Guayaquil
Guayaquil2 stops$632
Cali
Cali1 stop$618
Cusco
Cusco2 stops$1,053
Barranquilla
Barranquilla1 stop$611
Montevideo
Montevideo2 stops$1,191

Book Cheap Detroit to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South America

Sat, May 23 - Wed, May 27
Spirit Airlines Logo
8:25 pm - 12:26 pm
DTW
-
CTG
17h 01m
1 stop
Spirit Airlines Logo
1:31 pm - 7:52 am
CTG
-
DTW
17h 21m
2 stops
$348Spirit Airlines
Sat, May 23 - Wed, May 27
Spirit Airlines Logo
12:49 pm - 12:26 pm
DTW
-
CTG
24h 37m
2 stops
Spirit Airlines Logo
1:31 pm - 7:52 am
CTG
-
DTW
17h 21m
2 stops
$356Spirit Airlines
Wed, May 27 - Wed, Jun 3
Multiple Airlines Logo
6:00 am - 11:40 pm
DTW
-
MDE
18h 40m
2 stops
Multiple Airlines Logo
5:00 am - 8:30 am
MDE
-
DTW
26h 30m
3 stops
$523Multiple Airlines
Wed, May 27 - Wed, Jun 3
Multiple Airlines Logo
6:00 am - 11:35 pm
DTW
-
MDE
18h 35m
2 stops
Multiple Airlines Logo
6:39 am - 11:53 pm
MDE
-
DTW
16h 14m
2 stops
$524Multiple Airlines
Sat, Oct 31 - Mon, Nov 2
Air Canada Logo
6:15 pm - 2:15 am
DTW
-
LIM
33h 00m
2 stops
Air Canada Logo
8:00 am - 3:12 pm
LIM
-
DTW
31h 12m
1 stop
$560Air Canada
Sat, Oct 31 - Mon, Nov 2
Air Canada Logo
6:15 pm - 2:15 am
DTW
-
LIM
33h 00m
2 stops
Air Canada Logo
8:00 am - 5:36 pm
LIM
-
DTW
33h 36m
2 stops
$568Air Canada
Wed, Jun 10 - Mon, Jun 15
GOL Logo
6:57 pm - 11:00 pm
DTW
-
GIG
27h 03m
2 stops
GOL Logo
10:15 pm - 10:56 pm
GIG
-
DTW
25h 41m
2 stops
$636GOL
Mon, Aug 24 - Wed, Sep 2
American Airlines Logo
6:00 am - 8:30 pm
DTW
-
LIM
15h 30m
1 stop
American Airlines Logo
6:30 am - 11:08 pm
LIM
-
DTW
15h 38m
1 stop
$662American Airlines
Mon, Aug 24 - Wed, Sep 2
American Airlines Logo
4:25 pm - 4:11 am
DTW
-
LIM
12h 46m
1 stop
American Airlines Logo
10:00 pm - 4:13 pm
LIM
-
DTW
17h 13m
2 stops
$667American Airlines
Fri, Jun 12 - Mon, Jun 15
GOL Logo
6:57 pm - 6:35 am
DTW
-
GIG
58h 38m
2 stops
GOL Logo
6:25 pm - 10:56 pm
GIG
-
DTW
29h 31m
2 stops
$749GOL
Booking Insights

KAYAK's insights & trends for Detroit to South America flights

Get data-powered insights and trends into flights from Detroit to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South America is October, when tickets cost $105 (return) on average. On the other hand, the most expensive months are July and May, when the average cost of round-trip tickets is $347 and $343 respectively.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$166
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 22% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Detroit to South America

 
Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8458 reviews
7.8Entertainment
7.2Food
7.9Comfort
8.5Crew
8.1Boarding
Airline reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

8.0 ExcellentMatthew, May 2026
OKC - ATL
Read more Delta reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

The crew was very attentive through out the flight. Seats were comfortable, nice flight bag with pillow and blanket. Food was okay, since it was a overnight flight seemed to go by fast.

The flight attendant on my side of business class seemed like a novice and did not provide good service. Otherwise the flight was good and the entertainment system was very good. No free WiFi.

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

I did not like anything because the flight was cancelled yesterday and I did not get to arrive on time in Toronto as I was rebooked with another airline. This caused me to be really stressed out as I am an individual with back injury and to be forced to stay longer in an airport to accommodate a change of airline and the transfers associated with it Due to this I am probably not going to book through your website to eliminate this potentially chaos in the future

shittiest airline in the hemisphere. To improve - start thinking you're flying people, not cattle

Easy boarding, inflight refreshments came on time and comfortable seat

It was good that our flight left early. It was a nice smooth flight and landing.

All good……but luggage didn’t make it on the airplane. Had to wait 3 days. Was a bummer.

Small suitcase used for carryon the last time was refused by boarding crew this time. Appears to be at the discretion and mood of the person on the day. Flight was only half booked, there would have been no problem with space.

It was a problem because there was a delay where we sat before taking off from newark,then when landed in Toronto we sat on tarmac and they wouldn't let us out for a long period of time. When we finally were released to the airport in Toronto the attendant scanned our boarding pass that we were here for our connection to Brazil. We ran all the way to the gate and they said at the gate the door is shut so we can not let you on the plane. We explained that we were checked in by the attendant when we arrived at Toronto airport to go to Brazil and they should not have shut the door. We were ignored at the gate

Flight home was delayed multiple times, did not get home until 2am

the check-in lady at ORD was extremely rude and unprofessional. very disappointed as it was supposed to be a celebration for my wife's birthday and it really put a damper on things. if i wanted to be treated like trash, i would have flown Economy! (as opposed to business class)

My original flight was cancelled and then rebooked four hours later on a recovery flight, but I was checked in as stanby and had no seats so as a family of four we were concerned about not being seated altogether. Our flight then got delayed by another 1.5 hours and when seats were assigned at the gate, three of the four of us were together and we could get my wife closer, they offered no assistance.

Shut down without prior notice End up with spending lots of extra $$$

There was a crack in my window seal. And Spirit is now closed forever.

The company went out of business and now I'm stuck in Ft. Lauderdale. Would not recommend.

Spirit changed flight times by 12 hours with coming and going so I refunded tickets and drove

The airline cancel mi flight, lost a lot of money!!!

Everyone was nice but it's budget. There's nothing free and no entertainment

Broke my bag and offered no support or solution afterwards

Always Good ,… Spirit customers are high class Delta customers are self proclaimed elites and American crews you can hear them complain about everything (they’re loud)

Flight was delayed more than 3 hours, and the metro had stopped running by the time we got to the terminal well past midnight, so I was stranded, alone, with no way to get home until the metro started up the next morning.

Flight was delayed due to waiting for crew! Flight attendants did not offer us food or drinks. Did not communicate with them at all other than at boarding and leaving the plane.

Everything you need to know for your flight to South America

Information on your arrival and departure airports