$191 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Detroit to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$570
Bogotá
Bogotá1 stop$538
Sao Paulo
Sao Paulo3 stops$690
Santiago
Santiago3 stops$829
Cartagena
Cartagena1 stop$374
Quito
Quito1 stop$621
Guayaquil
Guayaquil1 stop$486
Cali
Cali1 stop$573
Cusco
Cusco3 stops$984
Barranquilla
Barranquilla1 stop$591
Montevideo
Montevideo2 stops$1,183
Lima
Lima2 stops$570
Bogotá
Bogotá1 stop$538
Sao Paulo
Sao Paulo3 stops$690
Santiago
Santiago3 stops$829
Cartagena
Cartagena1 stop$374
Quito
Quito1 stop$621
Guayaquil
Guayaquil1 stop$486
Cali
Cali1 stop$573
Cusco
Cusco3 stops$984
Barranquilla
Barranquilla1 stop$591
Montevideo
Montevideo2 stops$1,183

Book Cheap Detroit to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South America

Wed, Jun 10 - Wed, Jun 17
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$374Spirit Airlines
Wed, May 27 - Wed, Jun 3
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$376Spirit Airlines
Wed, May 27 - Wed, Jun 3
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 8:30 am
CTG
-
DTW
17h 59m
2 stops
$378Spirit Airlines
Sat, May 9 - Sat, May 16
Air Canada Logo
10:15 am - 4:05 am
DTW
-
BOG
18h 50m
1 stop
Air Canada Logo
9:00 am - 9:25 pm
BOG
-
DTW
11h 25m
1 stop
$563Air Canada
Fri, Sep 11 - Mon, Sep 21
Air Canada Logo
10:05 am - 2:30 pm
DTW
-
EZE
27h 25m
2 stops
Air Canada Logo
4:35 pm - 9:29 pm
EZE
-
DTW
29h 54m
2 stops
$971Air Canada
Mon, Oct 5 - Mon, Oct 12
LATAM Airlines Logo
7:45 pm - 10:00 am
DTW
-
CUZ
15h 15m
2 stops
LATAM Airlines Logo
6:10 pm - 3:11 pm
CUZ
-
DTW
20h 01m
2 stops
$1,013LATAM Airlines
Thu, Oct 15 - Sun, Oct 25
LATAM Airlines Logo
6:30 pm - 1:35 pm
DTW
-
CUZ
20h 05m
2 stops
LATAM Airlines Logo
6:10 pm - 3:11 pm
CUZ
-
DTW
20h 01m
2 stops
$1,053LATAM Airlines
Sat, Aug 15 - Mon, Aug 24
Delta Logo
8:25 am - 1:00 am
DTW
-
CUZ
17h 35m
2 stops
Delta Logo
8:35 am - 3:11 pm
CUZ
-
DTW
29h 36m
2 stops
$1,069Delta
Mon, Aug 3 - Thu, Aug 13
American Airlines Logo
6:00 am - 7:20 am
DTW
-
CUZ
26h 20m
2 stops
American Airlines Logo
8:05 pm - 3:55 pm
CUZ
-
DTW
18h 50m
2 stops
$1,070American Airlines
Mon, Aug 3 - Thu, Aug 13
American Airlines Logo
6:00 am - 7:20 am
DTW
-
CUZ
26h 20m
2 stops
American Airlines Logo
8:05 pm - 3:55 pm
CUZ
-
DTW
18h 50m
2 stops
$1,108American Airlines
Booking Insights

KAYAK's insights & trends for Detroit to South America flights

Get data-powered insights and trends into flights from Detroit to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South America is October, when tickets cost $105 (return) on average. On the other hand, the most expensive months are July and May, when the average cost of round-trip tickets is $347 and $343 respectively.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South America, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$196
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 22% increase in price.
Flight from Detroit to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Detroit to South America

 
Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8466 reviews
8.1Boarding
7.2Food
7.8Entertainment
7.9Comfort
8.5Crew
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

shittiest airline in the hemisphere. To improve - start thinking you're flying people, not cattle

Easy boarding, inflight refreshments came on time and comfortable seat

It was good that our flight left early. It was a nice smooth flight and landing.

All good……but luggage didn’t make it on the airplane. Had to wait 3 days. Was a bummer.

Small suitcase used for carryon the last time was refused by boarding crew this time. Appears to be at the discretion and mood of the person on the day. Flight was only half booked, there would have been no problem with space.

It was a problem because there was a delay where we sat before taking off from newark,then when landed in Toronto we sat on tarmac and they wouldn't let us out for a long period of time. When we finally were released to the airport in Toronto the attendant scanned our boarding pass that we were here for our connection to Brazil. We ran all the way to the gate and they said at the gate the door is shut so we can not let you on the plane. We explained that we were checked in by the attendant when we arrived at Toronto airport to go to Brazil and they should not have shut the door. We were ignored at the gate

Flight home was delayed multiple times, did not get home until 2am

the check-in lady at ORD was extremely rude and unprofessional. very disappointed as it was supposed to be a celebration for my wife's birthday and it really put a damper on things. if i wanted to be treated like trash, i would have flown Economy! (as opposed to business class)

My original flight was cancelled and then rebooked four hours later on a recovery flight, but I was checked in as stanby and had no seats so as a family of four we were concerned about not being seated altogether. Our flight then got delayed by another 1.5 hours and when seats were assigned at the gate, three of the four of us were together and we could get my wife closer, they offered no assistance.

I bought a ticket from Kayak. When I got to the airport, the was no ticket. I had to pay 5X to get to my destination. No response received from Kayak. I will NEVER use them again.

Wonderful! Very polite crew that was dedicated to excellent customer service

Everyone was nice but it's budget. There's nothing free and no entertainment

The flight was delayed for over an hour. No one at the gate said anything about the flight being delayed. I had to rely on my phone for updates. Absolutely no communication at the gate.

The AC broke and we were onboard for 2 hrs waiting for them to fix it. It was so hot and we could not get any water or anything to drink. They finally let us off the plane after the second attempt and we boarded a new plane. We didn't land till 12:15am!

The boarding process was simple but the seats were very uncomfortable. The staff lady was also very hard to understand when she spoke over the intercom about procedures and updates. Other staff members seemed like they were just tired and didnt want to be on the plane. Im used to happy attendants and being able to understand what is said over the speakers.

Broke my bag and offered no support or solution afterwards

Always Good ,… Spirit customers are high class Delta customers are self proclaimed elites and American crews you can hear them complain about everything (they’re loud)

Flight was delayed more than 3 hours, and the metro had stopped running by the time we got to the terminal well past midnight, so I was stranded, alone, with no way to get home until the metro started up the next morning.

Flight was delayed due to waiting for crew! Flight attendants did not offer us food or drinks. Did not communicate with them at all other than at boarding and leaving the plane.

Crew was very nice. Take off and landing were great. Economy seats are not comfortable. Extra cost for snacks.

Everything you need to know for your flight to South America

Information on your arrival and departure airports