$160 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Detroit to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$574
Bogotá
Bogotá1 stop$422
Sao Paulo
Sao Paulo3 stops$715
Santiago
Santiago3 stops$821
Cartagena
Cartagena1 stop$318
Quito
Quito2 stops$562
Guayaquil
Guayaquil1 stop$445
Cali
Cali2 stops$559
Cusco
Cusco3 stops$830
Barranquilla
Barranquilla1 stop$407
Montevideo
Montevideo3 stops$1,092
Lima
Lima2 stops$574
Bogotá
Bogotá1 stop$422
Sao Paulo
Sao Paulo3 stops$715
Santiago
Santiago3 stops$821
Cartagena
Cartagena1 stop$318
Quito
Quito2 stops$562
Guayaquil
Guayaquil1 stop$445
Cali
Cali2 stops$559
Cusco
Cusco3 stops$830
Barranquilla
Barranquilla1 stop$407
Montevideo
Montevideo3 stops$1,092

Book Cheap Detroit to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South America

Mon, May 11 - Fri, May 15
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 7:52 am
CTG
-
DTW
17h 21m
2 stops
$318Spirit Airlines
Mon, May 11 - Fri, May 15
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$324Spirit Airlines
Wed, Jun 10 - Wed, Jun 17
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$354Spirit Airlines
Sun, May 10 - Thu, May 14
Spirit Airlines Logo
5:42 pm - 12:26 pm
DTW
-
CTG
19h 44m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$367Spirit Airlines
Tue, Oct 6 - Mon, Oct 19
Air Canada Logo
10:05 am - 2:30 pm
DTW
-
EZE
27h 25m
2 stops
Air Canada Logo
4:35 pm - 9:29 pm
EZE
-
DTW
29h 54m
2 stops
$976Air Canada
Mon, Sep 14 - Wed, Sep 23
Air Canada Logo
10:05 am - 2:30 pm
DTW
-
EZE
51h 25m
3 stops
Air Canada Logo
4:35 pm - 9:29 pm
EZE
-
DTW
29h 54m
2 stops
$979Air Canada
Thu, Sep 10 - Sun, Sep 20
LATAM Airlines Logo
8:25 am - 1:00 am
DTW
-
CUZ
17h 35m
2 stops
LATAM Airlines Logo
6:45 pm - 3:11 pm
CUZ
-
DTW
19h 26m
2 stops
$1,021LATAM Airlines
Fri, Aug 14 - Mon, Aug 24
Delta Logo
10:15 am - 1:00 am
DTW
-
CUZ
15h 45m
2 stops
Delta Logo
9:05 am - 3:11 pm
CUZ
-
DTW
29h 06m
2 stops
$1,069Delta
Wed, Aug 5 - Thu, Aug 13
American Airlines Logo
6:00 am - 6:35 am
DTW
-
CUZ
25h 35m
2 stops
American Airlines Logo
8:05 pm - 3:55 pm
CUZ
-
DTW
18h 50m
2 stops
$1,070American Airlines
Fri, Sep 25 - Fri, Oct 9
LATAM Airlines Logo
2:00 pm - 10:00 am
DTW
-
CUZ
21h 00m
2 stops
LATAM Airlines Logo
11:20 pm - 9:40 pm
CUZ
-
DTW
21h 20m
2 stops
$1,085LATAM Airlines
Booking Insights

KAYAK's insights & trends for Detroit to South America flights

Get data-powered insights and trends into flights from Detroit to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South America is April, when tickets cost $502 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $1,111 and $993 respectively.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South America, you should book around 4 weeks before departure, which saves you about 20% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$158
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Detroit to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Detroit to South America

 
Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8444 reviews
7.8Entertainment
8.5Crew
7.9Comfort
8.1Boarding
7.2Food
Airline reviews

Everything was great. The only issue is unfixable. Seats are too small. 😁🤪

10.0 ExcellentAnonymous, Apr 2026
ATL - AMS
Read more Delta reviews

Everything was great. The only issue is unfixable. Seats are too small. 😁🤪

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Crew was nice, meal was good. Entertainment had to be rebooted 3 times and still did not work. Turns out there was residue on screen, it needed to be cleaned to prevent the touchscreen buttons from continuously activating. I had entertainment for the last 45 minutes of a 5 hour 45 minute flight. Really unacceptable for first class. Flight attendent indicated your cleaning solution creates this problem. Seems as if this is widely known, you should be using a different product or cleaning better. Really really disappointing which simply added to the wi fi on your planes with reliably never ever works.

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

Very old plane with no inflight entertainment. I purchased the internet pass and it was nearly unusable.

My tray was broken so i had no place to work or eat except my lap. Flight attendant said I would get an email with some credit or miles, it was a complete waste of time as I could only function at about 20% of normal. I have not received anything yet.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

For a 4 1/2 hour international flight all we got was 1 small pack of cookies and a drink. You had to watch movies on your own devise.

Airlines should be prohibited from using the seats they get away with.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

It was good that our flight left early. It was a nice smooth flight and landing.

All good……but luggage didn’t make it on the airplane. Had to wait 3 days. Was a bummer.

Small suitcase used for carryon the last time was refused by boarding crew this time. Appears to be at the discretion and mood of the person on the day. Flight was only half booked, there would have been no problem with space.

It was a problem because there was a delay where we sat before taking off from newark,then when landed in Toronto we sat on tarmac and they wouldn't let us out for a long period of time. When we finally were released to the airport in Toronto the attendant scanned our boarding pass that we were here for our connection to Brazil. We ran all the way to the gate and they said at the gate the door is shut so we can not let you on the plane. We explained that we were checked in by the attendant when we arrived at Toronto airport to go to Brazil and they should not have shut the door. We were ignored at the gate

Flight home was delayed multiple times, did not get home until 2am

the check-in lady at ORD was extremely rude and unprofessional. very disappointed as it was supposed to be a celebration for my wife's birthday and it really put a damper on things. if i wanted to be treated like trash, i would have flown Economy! (as opposed to business class)

My original flight was cancelled and then rebooked four hours later on a recovery flight, but I was checked in as stanby and had no seats so as a family of four we were concerned about not being seated altogether. Our flight then got delayed by another 1.5 hours and when seats were assigned at the gate, three of the four of us were together and we could get my wife closer, they offered no assistance.

I bought a ticket from Kayak. When I got to the airport, the was no ticket. I had to pay 5X to get to my destination. No response received from Kayak. I will NEVER use them again.

My wallet was stolen while I was sleeping on the plane.

Good boarding but extremely cold temperature in both flights (60 F!).

They canceled my flight and never told me. There was no follow up email. I had to buy another ticket the day of.

Easy to get our TSA pre check #added. Flight crew was great and entertaining and we landed early!

Flight was delayed 6plus hours Did not take flight Customer service was terrible Will never fly again and will spread how terrible you are You stink

I didnt have a flight. Kayak must be on drugs because I confirmed with spirit that I had no booked flight.

We were surprised to be charged $99 for a personal item. And of course everything offered on the flight was an additional charge. Other than that the pilot flew and landed the plane well and the attendants and fellow passengers were nice enough.

Broke my bag and offered no support or solution afterwards

Always Good ,… Spirit customers are high class Delta customers are self proclaimed elites and American crews you can hear them complain about everything (they’re loud)

Flight was delayed more than 3 hours, and the metro had stopped running by the time we got to the terminal well past midnight, so I was stranded, alone, with no way to get home until the metro started up the next morning.

Flight was delayed due to waiting for crew! Flight attendants did not offer us food or drinks. Did not communicate with them at all other than at boarding and leaving the plane.

Crew was very nice. Take off and landing were great. Economy seats are not comfortable. Extra cost for snacks.

Everything you need to know for your flight to South America

Information on your arrival and departure airports