$182 Find Cheap Flights from Detroit to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Detroit to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$735
Bogotá
Bogotá1 stop$443
Sao Paulo
Sao Paulo1 stop$693
Santiago
Santiago2 stops$1,009
Cartagena
Cartagena1 stop$416
Quito
Quito1 stop$571
Guayaquil
Guayaquil2 stops$397
Cali
Cali2 stops$493
Cusco
Cusco2 stops$1,095
Barranquilla
Barranquilla2 stops$629
Montevideo
Montevideo2 stops$1,145
Lima
Lima1 stop$735
Bogotá
Bogotá1 stop$443
Sao Paulo
Sao Paulo1 stop$693
Santiago
Santiago2 stops$1,009
Cartagena
Cartagena1 stop$416
Quito
Quito1 stop$571
Guayaquil
Guayaquil2 stops$397
Cali
Cali2 stops$493
Cusco
Cusco2 stops$1,095
Barranquilla
Barranquilla2 stops$629
Montevideo
Montevideo2 stops$1,145

Book Cheap Detroit to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South America

Sat, Sep 12 - Fri, Sep 18
JetBlue Logo
7:00 am - 2:20 pm
DTW
-
MDE
8h 20m
1 stop
JetBlue Logo
1:30 pm - 11:30 pm
MDE
-
DTW
9h 00m
1 stop
$364JetBlue
Sat, Sep 12 - Wed, Sep 16
JetBlue Logo
7:00 am - 2:20 pm
DTW
-
MDE
8h 20m
1 stop
JetBlue Logo
1:30 pm - 11:30 pm
MDE
-
DTW
9h 00m
1 stop
$365JetBlue
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
6:00 am - 12:35 pm
DTW
-
CTG
7h 35m
1 stop
American Airlines Logo
1:35 pm - 12:25 pm
CTG
-
DTW
21h 50m
2 stops
$427American Airlines
Thu, Aug 13 - Fri, Aug 21
American Airlines Logo
6:43 pm - 2:15 pm
DTW
-
CTG
20h 32m
2 stops
American Airlines Logo
1:35 pm - 10:21 am
CTG
-
DTW
19h 46m
2 stops
$436American Airlines
Tue, Sep 1 - Thu, Sep 17
LATAM Airlines Logo
9:09 am - 8:10 pm
DTW
-
BOG
12h 01m
1 stop
LATAM Airlines Logo
8:40 am - 9:20 pm
BOG
-
DTW
11h 40m
1 stop
$583LATAM Airlines
Tue, Sep 15 - Tue, Sep 22
LATAM Airlines Logo
2:32 pm - 5:00 am
DTW
-
LIM
15h 28m
1 stop
LATAM Airlines Logo
11:35 pm - 9:23 am
LIM
-
DTW
32h 48m
2 stops
$735LATAM Airlines
Fri, Aug 21 - Sat, Aug 29
GOL Logo
4:30 pm - 7:10 am
DTW
-
GIG
37h 40m
2 stops
GOL Logo
12:40 pm - 11:55 pm
GIG
-
DTW
36h 15m
2 stops
$802GOL
Fri, Aug 21 - Sat, Aug 29
GOL Logo
4:30 pm - 7:10 am
DTW
-
GIG
37h 40m
2 stops
GOL Logo
12:40 pm - 11:55 pm
GIG
-
DTW
36h 15m
2 stops
$806GOL
Fri, Nov 6 - Sun, Nov 15
Air Canada Logo
3:55 pm - 9:00 am
DTW
-
GRU
15h 05m
1 stop
Air Canada Logo
9:45 pm - 3:12 pm
GRU
-
DTW
19h 27m
1 stop
$845Air Canada
Tue, Nov 3 - Wed, Nov 18
Air Canada Logo
3:55 pm - 9:00 am
DTW
-
GRU
15h 05m
1 stop
Air Canada Logo
9:45 pm - 3:12 pm
GRU
-
DTW
19h 27m
1 stop
$850Air Canada
Booking Insights

KAYAK's insights & trends for Detroit to South America flights

Get data-powered insights and trends into flights from Detroit to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South America is October, when tickets cost $105 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $439 and $344 respectively.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South America, you should book around 4 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 10 weeks before departure.

Good to know

Low seasonJune
Cheapest flight$182
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Detroit to South America

 
Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8414 reviews
8.1Boarding
7.8Comfort
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

2.0 MediocreMargaret, Jun 2026
MSY - LGA
Read more Delta reviews

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

From checking to boarding, it was a seamless experience. The service agents were so helpful. The flight crew was so pleasant.

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

Original flight was delayed, then cancelled and the gate staff did not expedite rebooking. Also, no instructions were given that a ticket number was needed before being called to facilitate rebooking. This could have been much more organized.

Be on time? When not on time a circling for over an hour offer more than 1 bag of chips to the passengers? It was a 7 hour flight by the time we got done.

Five hour delays every hour, I wish it were all at once

Flight delayed four separate times. I’m now one hour hours late to landing.

LATAM clearly does not have well-established policies re: luggage for international flights to Lima followed by domestic flights within Peru (in my case, from Lima to Cuzco). On the way in, they forced me to pay $50 in Lima to check my second carry on bag (the three bags were included in the fare from JFK to Lima). On the return trip, they told me at check in that I would have to pay $50 again at the gate (she said they couldn't accept the money at check in) Then, at the gate, they initially told me I would have to pay several hundred dollars to check the big bag through to JFK. I protested, and showed them a print out of an email saying the checked bag was included between LIM and JFK. Than a second woman showed up, and told me I wouldn't have to pay anything at all -- which was great news, of course -- but that means I was incorrectly charged the extra $50 on the incoming flight. Basically, just a mess. Also, their website is completely non-functional -- it was very cleear that all the airport staff knew the website was nonfunctional, too.

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Very easy ! Use the kiosk and bag drop and right to security within 10 min

Checking bag at terminal was horrible. No agents to check us in and only 1 kiosk working. Boarding went ok. Crew onboard was very scattered rained. Missed our row while serving and then didn’t see them hardly again.

Crew was amazing, takeoff wonderful. The bathroom was disgusting from before takeoff the odor made the flight uncomfortable as you could smell the bathroom from the center of the plane where we were sitting. Smelled like raw sewage. My daughter was throwing up as we landed due to the smell and horrible turbulence as we approached Newark.

Airline tickets are not cheap. You expect reliable competent service. Thanks to canceled flights and botched transfers we arrived at our destination two days late. This is not acceptable

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

The entertainment they offer could use some games, and maybe they could add some cookies to the snack menu. And the automated messages are a bit repetitive. But it was comfortable temperature wise and the seats were comfortable. The crew is very polite and helpful

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

This planes staff was top tier. Everything went great and had a great flight home.

Food was great. Staff was phenomenal. Seats were a bit hard and could use a lot more entertainment options as far as movies to choose from. WiFi was good. Overall great trip.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Delayed flight due to maintenance and I have had multiple delayed flights due to maintenance in the last month plus

Excellent service. Flight attendance like Jessica,, on our flight, is a reason I wouldn’t mind flying through British Airways again. Jessica,, was very courteous and helpful.

The seats were extremely cramped, with very little legroom or personal space. There was no room left in the overhead bins for a backpack, and the space under the seat in front was so limited that I could barely fit my bag underneath. Overall, the seating arrangement felt very uncomfortable and overcrowded.

Significant delays on my trip to Chicago and my trip back to NY

Terrible boarding and first class experience. Nice staff but overall disorganized, dirty plane.

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

weather delay of almost 2 hours then we landed and our gate wasn't available so we waited another 30 min

Flight had mechanical issues and it was delayed 30 mins - some of us boarded and then had to deplane.

technology worked well and everything ran smoothly. The seats are quite cramped so please don't try to re-engineer the cabin to squeeze more bodies on board.

Delayed flight more than I hour. When boarding we spent some additional time on the plane before takeoff ....

1didnt have wheel chair I ordered wheel chair in my ticket flight

Flight was overbooked and seats assigned to multiple passengers. Delay 1 hour to sort out.

Good but I don’t received my bags yet is been 5days still no update

It was pretty straight forward, no glitches or hidden costs

It was a short flight so, everything went smoothly and we got to where we needed to be safely.

Didn’t make it on the flight. Delayed then had to be rebooked, which in turn had me waiting at the airport for another 8 hours before next flight

No TV on the flight. The charging outlet was not working. No food, even a sandwich. The served orange was poor quality.

Selected seats 5 months prior to date. Had email confirmation and seats were not honoured. Family did not sit together

Loved and was pleasantly surprised by the food!! Request Lufthansa to help transiting passengers at Munich (confusion whether to go thru passport control or not).

The flight was comfortable and the staff were helpful and friendly. However, we did not know we were flying PAL until we arrived in Canada, so it was a bit disconcerting. In addition, which port we were leaving from was confusing.

Everything you need to know for your flight to South America

Information on your arrival and departure airports