DTW - SCL

$708 Find Cheap Flights from Detroit to Santiago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to Santiago, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$972
Multiple Airlines
Tue 11/17Wed 12/2
DTW - SCL • 3 stops
Cheapest one-way
$708
Avianca
Sat 10/3
DTW - SCL • 2 stops
Top airlines
Aeromexico
Cheapest • from $1,091 (round-trip)
Delta
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Detroit and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $964 (round-trip)
Miami (MIA)
Shortest trip • 13h 23m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Detroit to Santiago (DTW-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to Santiago

Tue, Nov 17 - Wed, Dec 2
Multiple Airlines Logo
3:55 pm - 5:14 am
DTW
-
SCL
35h 19m
3 stops
Multiple Airlines Logo
7:25 am - 5:40 pm
SCL
-
DTW
36h 15m
2 stops
$972Multiple Airlines
Tue, Nov 17 - Wed, Dec 2
Multiple Airlines Logo
9:00 am - 10:15 pm
DTW
-
SCL
59h 15m
2 stops
Multiple Airlines Logo
8:25 am - 5:40 pm
SCL
-
DTW
35h 15m
2 stops
$1,005Multiple Airlines
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
6:07 pm - 5:14 am
DTW
-
SCL
35h 07m
2 stops
Multiple Airlines Logo
9:30 am - 5:30 pm
SCL
-
DTW
32h 00m
1 stop
$1,060Multiple Airlines
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
6:07 pm - 7:36 pm
DTW
-
SCL
25h 29m
2 stops
Multiple Airlines Logo
9:30 am - 5:30 pm
SCL
-
DTW
32h 00m
1 stop
$1,085Multiple Airlines
Tue, Nov 17 - Wed, Dec 2
Aeromexico Logo
9:00 am - 10:15 pm
DTW
-
SCL
59h 15m
2 stops
Aeromexico Logo
12:25 am - 6:10 pm
SCL
-
DTW
19h 45m
2 stops
$1,091Aeromexico
Tue, Nov 17 - Tue, Dec 1
Multiple Airlines Logo
3:55 pm - 5:14 am
DTW
-
SCL
35h 19m
3 stops
Multiple Airlines Logo
1:35 am - 5:00 am
SCL
-
DTW
29h 25m
3 stops
$1,113Multiple Airlines
Mon, Nov 30 - Mon, Jan 11
Multiple Airlines Logo
6:20 pm - 12:15 pm
DTW
-
SCL
15h 55m
1 stop
Multiple Airlines Logo
11:20 am - 12:44 am
SCL
-
DTW
15h 24m
2 stops
$1,133Multiple Airlines
Thu, Aug 13 - Tue, Aug 18
Multiple Airlines Logo
6:00 am - 4:45 am
DTW
-
SCL
22h 45m
2 stops
Multiple Airlines Logo
3:20 pm - 9:45 pm
SCL
-
DTW
30h 25m
2 stops
$1,143Multiple Airlines
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
6:00 am - 4:45 am
DTW
-
SCL
22h 45m
2 stops
Multiple Airlines Logo
3:20 pm - 3:20 pm
SCL
-
DTW
48h 00m
2 stops
$1,155Multiple Airlines
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
6:00 am - 11:20 pm
DTW
-
SCL
17h 20m
2 stops
Multiple Airlines Logo
3:20 pm - 9:45 pm
SCL
-
DTW
30h 25m
2 stops
$1,162Multiple Airlines
Booking Insights

KAYAK's insights & trends for Detroit to Santiago flights

Get data-powered insights and trends into flights from Detroit to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Detroit to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Detroit to Santiago were found on Aeromexico ($1,091) and American Airlines ($1,200).

Find deals

Good to know

Cheapest flight$708
Flight from Detroit to Santiago

When to book flights from Detroit to Santiago

Are your dates flexible? Find out the best times to travel from Detroit to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Detroit to Santiago flights

  • What is the cheapest flight from Detroit Metropolitan Wayne County Airport to Santiago?

    In the last 5 days, the lowest price for a flight from Detroit Metropolitan Wayne County Airport to Santiago was $708 for a one-way ticket and $972 for a round-trip.

  • Do I need a passport to fly between Detroit and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Detroit and on arrival in Santiago.

  • Which airports will I be using when flying from Detroit to Santiago?

    Detroit and Santiago are both served by 1 main airport. You will leave Detroit from Detroit Metropolitan Wayne County and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Detroit to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Detroit to Santiago?

    SkyTeam is the only airline alliance operating flights between Detroit and Santiago.

  • How does KAYAK find such low prices on flights from Detroit to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Detroit with another airline. Booking your flights between Detroit and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Detroit to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Detroit to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8455 reviews
8.1Boarding
7.8Comfort
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

Should never have had to go to Detroit from Orlando back to Tennessee!

6.0 GoodCynthia, Jun 2026
DTW - TYS
Read more Delta reviews

Should never have had to go to Detroit from Orlando back to Tennessee!

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Boarding was good. The flight was on time ( arrival was 20 minutes early). Inflight service was average ( US airlines have not mastered the skills of customer service yet). The food was mediocre. “ breakfast “ was downright awful and insulting. It was a piece of dough with mon descript filling that was supposed to be cheese omelette).

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

2+hrs delay without any reason provided and a cramped flight

Flight was delayed and no reasons provided. After the passengers were boarded, the crew made announcement that the captain has jot arrived and he would take another 15 mins. All passengers patiently sat until the captain came and started. Terrible experience!

Flight delay was frustrating, also you cannot checkin online without delta app, web browser check-in throw errors

Got on the plane and sat there for an hour before departure.

Everything you need to know for your flight from Detroit to Santiago

Information on your arrival and departure airports

Detroit (DTW)
Santiago (SCL)