DTW - SCL

$341 Find Cheap Flights from Detroit to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$643
Typical prices: $1,126-$1,291
Multiple Airlines
Thu 4/2Sat 4/11
DTW - SCL • 2 stops
Cheapest one-way
$341
Multiple Airlines
Sat 3/28
DTW - SCL • 3 stops
Top airlines
Air Canada
Cheapest • from $855 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Detroit to Santiago (DTW-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to Santiago

Thu, Apr 2 - Sat, Apr 11
Multiple Airlines Logo
5:20 am - 2:30 pm
DTW
-
SCL
32h 10m
2 stops
Multiple Airlines Logo
5:00 am - 12:08 pm
SCL
-
DTW
31h 08m
3 stops
$643Multiple Airlines
Thu, Apr 2 - Sat, Apr 11
Multiple Airlines Logo
5:20 am - 2:30 pm
DTW
-
SCL
32h 10m
2 stops
Multiple Airlines Logo
5:00 am - 12:08 pm
SCL
-
DTW
31h 08m
3 stops
$648Multiple Airlines
Thu, Apr 2 - Sat, Apr 11
Multiple Airlines Logo
5:20 am - 6:30 am
DTW
-
SCL
24h 10m
2 stops
Multiple Airlines Logo
5:00 am - 11:59 pm
SCL
-
DTW
18h 59m
2 stops
$654Multiple Airlines
Thu, Apr 2 - Sat, Apr 11
Multiple Airlines Logo
5:20 am - 6:30 am
DTW
-
SCL
24h 10m
2 stops
Multiple Airlines Logo
5:00 am - 11:59 pm
SCL
-
DTW
18h 59m
2 stops
$659Multiple Airlines
Wed, Mar 25 - Tue, Apr 7
Multiple Airlines Logo
6:00 am - 10:39 am
DTW
-
SCL
27h 39m
3 stops
Multiple Airlines Logo
12:40 am - 11:59 pm
SCL
-
DTW
23h 19m
3 stops
$664Multiple Airlines
Wed, Mar 25 - Tue, Apr 7
Multiple Airlines Logo
9:53 pm - 5:55 am
DTW
-
SCL
31h 02m
1 stop
Multiple Airlines Logo
12:40 am - 7:56 pm
SCL
-
DTW
43h 16m
3 stops
$673Multiple Airlines
Wed, Mar 25 - Wed, Apr 8
Multiple Airlines Logo
11:34 am - 5:55 am
DTW
-
SCL
17h 21m
1 stop
Multiple Airlines Logo
8:30 am - 7:56 pm
SCL
-
DTW
35h 26m
2 stops
$683Multiple Airlines
Wed, Mar 25 - Wed, Apr 8
Multiple Airlines Logo
11:34 am - 5:55 am
DTW
-
SCL
17h 21m
1 stop
Multiple Airlines Logo
10:30 am - 7:56 pm
SCL
-
DTW
33h 26m
1 stop
$690Multiple Airlines
Thu, Apr 2 - Sat, Apr 11
Multiple Airlines Logo
5:20 am - 12:05 pm
DTW
-
SCL
29h 45m
3 stops
Multiple Airlines Logo
5:00 am - 12:08 pm
SCL
-
DTW
31h 08m
3 stops
$708Multiple Airlines
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
2:15 pm - 10:15 pm
DTW
-
SCL
31h 00m
2 stops
Multiple Airlines Logo
7:15 am - 11:59 pm
SCL
-
DTW
17h 44m
2 stops
$710Multiple Airlines
Booking Insights

KAYAK's insights & trends for Detroit to Santiago flights

Get data-powered insights and trends into flights from Detroit to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Detroit Metropolitan Wayne County Airport to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Detroit Metropolitan Wayne County Airport to Santiago departing in April.

Good to know

Low seasonOctober
Cheapest flight$341
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from Detroit to Santiago

When to book flights from Detroit to Santiago

Are your dates flexible? Find out the best times to travel from Detroit to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Detroit to Santiago flights

  • What is the cheapest flight from Detroit Metropolitan Wayne County Airport to Santiago?

    In the last 3 days, the lowest price for a flight from Detroit Metropolitan Wayne County Airport to Santiago was $341 for a one-way ticket and $609 for a round-trip.

  • Do I need a passport to fly between Detroit and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Detroit and on arrival in Santiago.

  • Which airports will I be using when flying from Detroit to Santiago?

    Detroit and Santiago are both served by 1 main airport. You will leave Detroit from Detroit Metropolitan Wayne County and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Detroit to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Detroit to Santiago?

    SkyTeam is the only airline alliance operating flights between Detroit and Santiago.

  • Which is the best airline for flights from Detroit to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Detroit to Santiago are Delta and LATAM Airlines. With an average price for the route of $1,222 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $1,368 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Detroit to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Detroit with another airline. Booking your flights between Detroit and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • Which airlines provide the cheapest flights from Detroit to Santiago?

    In the past 3 days, the cheapest round-trip tickets from Detroit to Santiago were found on Air Canada ($855) and United Airlines ($873).

Reviews of the top airlines flying from Detroit to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Detroit to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8181 reviews
7.2Food
7.8Entertainment
8.1Boarding
7.9Comfort
8.5Crew
Airline reviews

Awesome! On time flight, early arrival, and a complimentary upgrade!

10.0 ExcellentSarah, Feb 2026
SFO - LAX
Read more Delta reviews

Awesome! On time flight, early arrival, and a complimentary upgrade!

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

We departed early and made up time in the air allowing us to arrive 30 minutes early. Capt was incredibly genuine and thanked every passenger for flying with Delta. Completely humble and professional!

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

No wheel chair as requested at Atlanta arrival on first flight.

Only freetext wifi was available in flight; browsing WiFi required payment. Since the seats had no in flight entertainment, Delta should revisit this policy on this longer flight.

Only water, tea or coffee served midflight, even to comfort seating. Man next to me needed two seats and took up a portion of my seat and Delta did nothing.

The flight was great as well as the airline staff

First class and monitors weren’t working for mine & my husbands. Eventually fixed, but quite annoyed as we bought first class. Also, No foot rests.

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Everything you need to know for your flight from Detroit to Santiago

Information on your arrival and departure airports