DTW - SCL

$329 Find Cheap Flights from Detroit to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to Santiago, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$771
Multiple Airlines
Sun 4/26Sat 5/2
DTW - SCL • 3 stops
Cheapest one-way
$329
Multiple Airlines
Tue 5/12
DTW - SCL • 3 stops
Top airlines
American Airlines
Cheapest • from $971 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Detroit and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Miami (MIA)
Cheapest • Avg $768 (round-trip)
Toronto (YYZ)
Shortest trip • 13h 15m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Detroit to Santiago (DTW-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to Santiago

Sun, Apr 26 - Sat, May 2
Multiple Airlines Logo
6:50 am - 2:15 pm
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
3:20 pm - 10:33 pm
SCL
-
DTW
31h 13m
2 stops
$771Multiple Airlines
Sun, Apr 26 - Sat, May 2
Multiple Airlines Logo
5:25 pm - 4:45 am
DTW
-
SCL
35h 20m
2 stops
Multiple Airlines Logo
6:40 am - 12:52 pm
SCL
-
DTW
30h 12m
2 stops
$773Multiple Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
8:30 pm - 3:55 am
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
6:40 am - 2:51 pm
SCL
-
DTW
32h 11m
3 stops
$774Multiple Airlines
Sat, Apr 25 - Fri, May 1
Multiple Airlines Logo
5:25 pm - 4:45 am
DTW
-
SCL
35h 20m
2 stops
Multiple Airlines Logo
12:30 am - 11:59 pm
SCL
-
DTW
23h 29m
2 stops
$784Multiple Airlines
Mon, Apr 27 - Mon, May 4
Multiple Airlines Logo
8:30 pm - 5:30 am
DTW
-
SCL
33h 00m
3 stops
Multiple Airlines Logo
3:20 pm - 11:53 pm
SCL
-
DTW
32h 33m
2 stops
$788Multiple Airlines
Sun, Apr 26 - Fri, May 1
Multiple Airlines Logo
6:50 am - 2:15 pm
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
12:30 am - 8:02 am
SCL
-
DTW
31h 32m
3 stops
$790Multiple Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
8:30 pm - 3:55 am
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
6:40 am - 2:51 pm
SCL
-
DTW
32h 11m
3 stops
$791Multiple Airlines
Mon, Apr 27 - Mon, May 11
Multiple Airlines Logo
5:25 pm - 2:15 pm
DTW
-
SCL
20h 50m
2 stops
Multiple Airlines Logo
6:40 am - 7:52 am
SCL
-
DTW
25h 12m
2 stops
$792Multiple Airlines
Sat, Apr 25 - Fri, May 1
Multiple Airlines Logo
8:30 pm - 1:30 pm
DTW
-
SCL
41h 00m
3 stops
Multiple Airlines Logo
12:30 am - 11:59 pm
SCL
-
DTW
23h 29m
2 stops
$794Multiple Airlines
Sat, Apr 25 - Fri, May 1
Multiple Airlines Logo
8:30 pm - 3:55 am
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
12:30 am - 11:59 pm
SCL
-
DTW
23h 29m
2 stops
$802Multiple Airlines
Booking Insights

KAYAK's insights & trends for Detroit to Santiago flights

Get data-powered insights and trends into flights from Detroit to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Detroit to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Detroit to Santiago were found on American Airlines ($971) and LATAM Airlines ($1,122).

Find deals

Good to know

Low seasonOctober
Cheapest flight$329
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Detroit to Santiago

When to book flights from Detroit to Santiago

Are your dates flexible? Find out the best times to travel from Detroit to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Detroit to Santiago flights

  • What is the cheapest flight from Detroit Metropolitan Wayne County Airport to Santiago?

    In the last 3 days, the lowest price for a flight from Detroit Metropolitan Wayne County Airport to Santiago was $329 for a one-way ticket and $771 for a round-trip.

  • Do I need a passport to fly between Detroit and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Detroit and on arrival in Santiago.

  • Which airports will I be using when flying from Detroit to Santiago?

    Detroit and Santiago are both served by 1 main airport. You will leave Detroit from Detroit Metropolitan Wayne County and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Detroit to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Detroit to Santiago?

    SkyTeam is the only airline alliance operating flights between Detroit and Santiago.

  • How does KAYAK find such low prices on flights from Detroit to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Detroit with another airline. Booking your flights between Detroit and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Detroit to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Detroit to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8364 reviews
7.8Entertainment
7.2Food
8.1Boarding
7.9Comfort
8.5Crew
Airline reviews

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

10.0 ExcellentAnonymous, Mar 2026
SAT - LAX
Read more Delta reviews

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

Delta is always a wonderful experience. A clean plane and the crew is really friendly.

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

Everything you need to know for your flight from Detroit to Santiago

Information on your arrival and departure airports

Detroit (DTW)
Santiago (SCL)