Find flights
When to book
FAQs & Tips
Direct Flights
Deals

Find cheap flights from Iowa to Chicago from $55

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Chicago departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
vie. 6/7
vie. 6/14

Search hundreds of travel sites at once for deals on flights to Chicago

In the last 7 days travelers have searched 43,968,530 times on KAYAK, and here is why:

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Bundle and saveSave money when you bundle your flight + hotel.

Good to know

Low season

January

High season

July

Cheapest flight

$55
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Des Moines to Chicago O'Hare Airport

FAQs for booking flights from Iowa to Chicago

  • How does KAYAK find such low prices on flights from Iowa to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to Iowa with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Iowa to Chicago?

Find which airlines fly direct from Iowa to Chicago, which days they fly and book direct flights.

Nonstop departures

Iowa to Chicago

Monday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Tuesday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Wednesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Thursday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Friday

ANA, Aer Lingus, Aerolineas Argentinas, +81 more

ANA, Aer Lingus, +82 more

Saturday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Sunday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

See more direct flights

Nonstop returns

Chicago to Iowa

Monday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Tuesday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Wednesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Thursday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Friday

ANA, Aer Lingus, Aerolineas Argentinas, +81 more

ANA, Aer Lingus, +82 more

Saturday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Sunday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

See more direct flights
See more direct flights

Book cheap flights from Iowa to Chicago

Recent round-trip flight deals

6/21vie.
nonstopUnited Airlines
1h 22mMCW-ORD
6/28vie.
nonstopUnited Airlines
1h 26mORD-MCW
$152
8/9vie.
nonstopUnited Airlines
1h 22mMCW-ORD
8/11dom.
nonstopUnited Airlines
1h 26mORD-MCW
$162
5/19dom.
nonstopSouthern / Mokulele
1h 40mBRL-ORD
5/20lun.
2 stopsSouthern / Mokulele
16h 10mORD-BRL
$191
5/19dom.
nonstopSouthern / Mokulele
1h 40mBRL-ORD
5/20lun.
nonstopSouthern / Mokulele
1h 40mORD-BRL
$195
5/18sáb.
1 stopFrontier
13h 36mDSM-MDW
5/21mar.
1 stopFrontier
24h 30mMDW-DSM
$215
6/4mar.
nonstopAmerican Airlines
1h 15mCID-ORD
6/5mié.
nonstopAmerican Airlines
1h 13mORD-CID
$229
6/3lun.
1 stop
14h 44mCID-ORD
6/7vie.
1 stop
13h 16mORD-CID
$234
6/7vie.
1 stop
14h 50mCID-ORD
6/9dom.
2 stops
20h 44mORD-CID
$243
8/7mié.
nonstopAmerican Airlines
1h 12mCID-ORD
8/9vie.
nonstopAmerican Airlines
1h 08mORD-CID
$249
6/13jue.
1 stopFrontier
7h 21mDSM-MDW
6/14vie.
1 stopFrontier
8h 29mMDW-DSM
$258

Search by stops

Search by airline

Search by price

Recent one-way flight deals

5/22mié.
1 stopFrontier
8h 58mDSM-ORD
$55
5/15mié.
1 stopFrontier
9h 31mDSM-ORD
$89
5/20lun.
2 stops
18h 29mCID-ORD
$93
5/17vie.
nonstopSouthern / Mokulele
1h 40mBRL-ORD
$103
6/3lun.
2 stops
24h 55mDSM-ORD
$104
6/13jue.
nonstopUnited Airlines
1h 22mMCW-ORD
$109
7/13sáb.
nonstopUnited Airlines
1h 44mSUX-ORD
$110
5/28mar.
nonstopAmerican Airlines
1h 10mCID-ORD
$115
7/30mar.
nonstopAmerican Airlines
1h 15mCID-ORD
$125
5/17vie.
2 stopsSouthern / Mokulele
10h 07mBRL-ORD
$144

Search by stops

Search by airline

Search by price

Last minute flights from Iowa to Chicago

Last minute flight, train and bus deals

5/9jue.
nonstopSouthern / Mokulele
1h 40mBRL-ORD
5/13lun.
multi-stopSouthern / Mokulele
17h 25mORD-BRL
$199
5/9jue.
nonstopSouthern / Mokulele
1h 40mBRL-ORD
5/13lun.
nonstopSouthern / Mokulele
1h 40mORD-BRL
$209
5/11sáb.
multi-stopFrontier
17h 18mDSM-MDW
5/18sáb.
multi-stopFrontier
15h 28mMDW-DSM
$324
5/11sáb.
multi-stopFrontier
17h 18mDSM-MDW
5/13lun.
multi-stopFrontier
9h 46mMDW-DSM
$327
5/13lun.
multi-stop
25h 17mDSM-ORD
5/16jue.
multi-stop
16h 07mORD-DSM
$372
5/13lun.
multi-stop
24h 12mDSM-ORD
5/16jue.
multi-stop
29h 41mORD-DSM
$380
5/10vie.
multi-stopUnited Airlines
19h 52mDSM-ORD
5/11sáb.
nonstopUnited Airlines
1h 30mORD-DSM
$438
5/11sáb.
multi-stopDelta
5h 07mDSM-ORD
5/18sáb.
multi-stopDelta
5h 03mORD-DSM
$444
5/9jue.
nonstopUnited Airlines
1h 28mDSM-ORD
5/11sáb.
nonstopUnited Airlines
1h 29mORD-DSM
$469
5/9jue.
multi-stopDelta
5h 02mDSM-MDW
5/11sáb.
multi-stopDelta
3h 53mMDW-DSM
$485

Search by stops

Search by airline

Search by price

Flights to Chicago

Return flight deals:

Chicago - Iowa

Cabin classes:

$551
$875
$695
$155