$42 Find Cheap Flights from Jacksonville to St. Louis - Compare and Save

These are the earliest and latest flight times available from Jacksonville to St. Louis:

• Earliest: departs at 5:30 am and lands at 7:44 am
• Latest: departs at 7:35 pm and lands at 9:49 pm.

The flight takes about 2h 14m.

Two cabin classes are available on flights from Jacksonville to St. Louis:

• Economy Class
• First Class

A nonstop flight from Jacksonville to St. Louis takes 2h 14m, covering 753 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Round-trip flights from Jacksonville to St. Louis range from $313 to $438, with an average of $367 over the past 12 months. Anything below $313 counts as a good deal.

Last-minute fares on this route - booked within 2 weeks of departure - run 45% above the route average of $367. Book 16 weeks before departure for the lowest fares.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $316 round-trip via Nashville Intl (BNA), compared to $377 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$90 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737 MAX 8 family is used most often on this route, operated mainly by Southwest. Other aircraft seen on the route include Boeing 737-800 Passenger/BBJ2 (winglets) variants.

Morning is the busiest departure period on Jacksonville to St. Louis flights, with 100% of flights leaving in that window. Afternoon departures account for 0%, evening flights for 0%, and night flights for 0%.

JetBlue is the only airline on the Jacksonville to St. Louis route offering in-flight Wi-Fi. Pricing depends on fare class.

One-way fares from Jacksonville to St. Louis are currently lower than usual. Average one-way flight prices are about $108, which is 48% below the typical average for this route.

Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
• Hertz
• Budget
• Alamo
• Enterprise Rent-A-Car
• Payless

Flights from Jacksonville to St. Louis usually depart from Jacksonville (JAX) and arrive at Lambert-St Louis (STL).

One-stop flights from Jacksonville to St. Louis most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 73% of one-stop connections
• Charlotte Douglas (CLT) - 21% of one-stop connections
• Chicago O'Hare Intl (ORD) - 2% of one-stop connections
• Nashville Intl (BNA) - 1% of one-stop connections

Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 28% on the Jacksonville to St. Louis route. Wednesday is the cheapest departure day at $341 round-trip on average, while Sunday is the most expensive at $473, a difference of $132. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Southwest operates flights between Jacksonville and St. Louis.

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 59m, compared with 4h 13m via Atlanta Hartsfield-Jackson (ATL) and 4h 36m via Charlotte Douglas (CLT).

St. Louis is 1 hour behind Jacksonville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Among airlines operating Jacksonville to St. Louis flights:

• Southwest: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Southwest: a cabin bag in Economy Class class
• JetBlue: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.