$78 Find Cheap Flights from St. Louis to Jacksonville - Compare and Save

These are the earliest and latest flight times available from St. Louis to Jacksonville:

• Earliest: departs at 8:10 am and lands at 10:10 am
• Latest: departs at 8:50 pm and lands at 10:50 pm.

The flight takes about 2h.

Two cabin classes are available on flights from St. Louis to Jacksonville:

• Economy Class
• First Class

A nonstop flight from St. Louis to Jacksonville takes 2h, covering 753 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Round-trip flights from St. Louis to Jacksonville range from $316 to $444, with an average of $366 over the past 12 months. Anything below $316 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 61% above the $366 route average. Book 12 weeks before departure for the lowest fares.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $178 round-trip via Washington, D.C. Reagan-National (DCA), compared to $368 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$90 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737 MAX 8 family is used most often on this route, operated mainly by Southwest and JetBlue. Other aircraft seen on the route include Boeing 737-800 Passenger/BBJ2 (winglets) variants.

Evening is the busiest departure period on St. Louis to Jacksonville flights, with 100% of flights leaving in that window. Morning departures account for 0%, afternoon flights for 0%, and night flights for 0%.

One-way fares from St. Louis to Jacksonville are currently lower than usual. Average one-way flight prices are about $121, which is 40% below the typical average for this route.

Jacksonville Airport (JAX) hosts 5 major car rental companies, with daily rates averaging $51 for economy cars. Top options include:

• Easirent
• Hertz
• Dollar
• Thrifty
• Budget

Flights from St. Louis to Jacksonville usually depart from Lambert-St Louis (STL) and arrive at Jacksonville (JAX).

One-stop flights from St. Louis to Jacksonville most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 69% of one-stop connections
• Charlotte Douglas (CLT) - 18% of one-stop connections
• Nashville Intl (BNA) - 6% of one-stop connections
• Chicago O'Hare Intl (ORD) - 4% of one-stop connections

Yes. Flexible dates can save you up to 20% on flights from St. Louis to Jacksonville. Wednesday is the cheapest departure day at $347 round-trip on average, while Sunday is the most expensive at $431, a difference of $84.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Southwest operates flights between St. Louis and Jacksonville.

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 4h 23m, compared with 4h 39m via Atlanta Hartsfield-Jackson (ATL) and 4h 42m via Charlotte Douglas (CLT).

Jacksonville is 1 hour ahead of St. Louis (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in Jacksonville are Mayo Clinic- Kinne Auditorium, Veterans Memorial Arena and EverBank Field. These are among the most viewed places in Jacksonville on KAYAK.

Among airlines operating St. Louis to Jacksonville flights:

• Southwest: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Southwest: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.