TYS - GUA

$339 Find Cheap Flights from Knoxville to Guatemala City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Guatemala City departing on 6/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Guatemala City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Guatemala City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Guatemala City, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$417
Multiple Airlines
Fri 7/31Sun 8/9
TYS - GUA • 2 stops
Cheapest one-way
$339
Multiple Airlines
Sat 6/27
TYS - GUA • 2 stops
Top airlines
Cheapest • from $663 (round-trip)
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Guatemala City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $633 (round-trip)
Shortest trip • 6h 38m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guatemala City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Guatemala City (TYS-GUA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Guatemala City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Guatemala City

Fri, Jul 31 - Sun, Aug 9
Multiple Airlines Logo
10:05 pm - 10:10 am
TYS
-
GUA
38h 05m
2 stops
Multiple Airlines Logo
3:47 pm - 8:18 pm
GUA
-
TYS
26h 31m
1 stop
$417Multiple Airlines
Sat, Aug 1 - Sun, Aug 9
Multiple Airlines Logo
6:00 am - 10:10 am
TYS
-
GUA
30h 10m
2 stops
Multiple Airlines Logo
3:47 pm - 8:18 pm
GUA
-
TYS
26h 31m
1 stop
$423Multiple Airlines
Sat, Aug 1 - Sun, Aug 9
Multiple Airlines Logo
5:59 pm - 2:41 pm
TYS
-
GUA
22h 42m
1 stop
Multiple Airlines Logo
3:47 pm - 8:18 pm
GUA
-
TYS
26h 31m
1 stop
$436Multiple Airlines
Fri, Jul 31 - Sun, Aug 9
Multiple Airlines Logo
7:20 pm - 2:41 pm
TYS
-
GUA
21h 21m
1 stop
Multiple Airlines Logo
3:47 pm - 8:18 pm
GUA
-
TYS
26h 31m
1 stop
$441Multiple Airlines
Wed, Jul 29 - Sun, Aug 9
Multiple Airlines Logo
2:23 pm - 2:41 pm
TYS
-
GUA
26h 18m
1 stop
Multiple Airlines Logo
3:47 pm - 8:18 pm
GUA
-
TYS
26h 31m
1 stop
$452Multiple Airlines
Mon, Jul 27 - Sun, Aug 9
Multiple Airlines Logo
10:05 pm - 2:41 pm
TYS
-
GUA
18h 36m
1 stop
Multiple Airlines Logo
3:47 pm - 8:18 pm
GUA
-
TYS
26h 31m
1 stop
$453Multiple Airlines
Sat, Aug 1 - Wed, Aug 12
Multiple Airlines Logo
5:59 pm - 2:41 pm
TYS
-
GUA
22h 42m
1 stop
Multiple Airlines Logo
5:25 am - 3:06 pm
GUA
-
TYS
31h 41m
2 stops
$461Multiple Airlines
Fri, Jul 31 - Wed, Aug 12
Multiple Airlines Logo
10:05 pm - 2:41 pm
TYS
-
GUA
18h 36m
1 stop
Multiple Airlines Logo
5:25 am - 3:06 pm
GUA
-
TYS
31h 41m
2 stops
$465Multiple Airlines
Wed, Jul 29 - Wed, Aug 12
Multiple Airlines Logo
2:23 pm - 2:41 pm
TYS
-
GUA
26h 18m
1 stop
Multiple Airlines Logo
5:25 am - 3:06 pm
GUA
-
TYS
31h 41m
2 stops
$476Multiple Airlines
Mon, Jul 27 - Wed, Aug 12
Multiple Airlines Logo
10:05 pm - 2:41 pm
TYS
-
GUA
18h 36m
1 stop
Multiple Airlines Logo
5:25 am - 3:06 pm
GUA
-
TYS
31h 41m
2 stops
$477Multiple Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Guatemala City flights

Get data-powered insights and trends into flights from Knoxville to Guatemala City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Guatemala City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Guatemala City were found on American Airlines ($663) and Delta ($690).

Good to know

Cheapest flight$339
Flight from Knoxville to Guatemala City

When to book flights from Knoxville to Guatemala City

Are your dates flexible? Find out the best times to travel from Knoxville to Guatemala City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Guatemala City

  • What is the cheapest flight from Knoxville to Guatemala City?

    In the last 3 days, the lowest price for a flight from Knoxville to Guatemala City was $339 for a one-way ticket and $417 for a round-trip.

  • Do I need a passport to fly between Knoxville and Guatemala City?

    Yes, you’ll need a passport to travel to Guatemala City from Knoxville.

  • Which aircraft models fly most regularly from Knoxville to Guatemala City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Guatemala City?

    oneworld is the only airline alliance operating flights between Knoxville and Guatemala City.

  • How does KAYAK find such low prices on flights from Knoxville to Guatemala City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Guatemala City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Guatemala City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guatemala City from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Guatemala City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guatemala City with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and GUA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Guatemala City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guatemala City from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Guatemala City

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Guatemala City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Guatemala City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11648 reviews
7.2Comfort
7.9Crew
7.5Boarding
6.9Entertainment
6.4Food
Airline reviews

The wifi experience is awful. I had to try again and again, taking over 30 minutes, to connect to the wifi. I had to watch the same two ads over and over until I was finally successful. Once connected, it was anything but "high speed" and disconnected at least three times during the flight.

6.0 GoodRay, May 2026
COU - ORD
Read more American Airlines reviews

The wifi experience is awful. I had to try again and again, taking over 30 minutes, to connect to the wifi. I had to watch the same two ads over and over until I was finally successful. Once connected, it was anything but "high speed" and disconnected at least three times during the flight.

Fine. Nothing to write home about. The plane left on time, and arrived on time.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

Seat comfort was poor (no lumbar or lower back support).

The airplane seats were spacious and comfortable, and the flight attendants were friendly and attentive. The food was delicious like never before. The blankets and toiletries were thoughtfully provided. The captain's navigation was steady and reliable. In short, having flown with Starlux, I won't consider any other airline next time.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Everything you need to know for your flight from Knoxville to Guatemala City

Information on your arrival and departure airports