TYS - GUA

$483 Find Cheap Flights from Knoxville to Guatemala City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Guatemala City departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Guatemala City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Guatemala City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Guatemala City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$664
American Airlines
Mon 11/2Mon 11/16
TYS - GUA • 1 stop
Cheapest one-way
$483
Multiple Airlines
Tue 7/7
TYS - GUA • 3 stops
Top airlines
Cheapest • from $664 (round-trip)
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Guatemala City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $657 (round-trip)
Shortest trip • 6h 38m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guatemala City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Guatemala City (TYS-GUA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Guatemala City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Guatemala City

Mon, Nov 2 - Mon, Nov 16
American Airlines Logo
5:07 pm - 10:37 am
TYS
-
GUA
18h 30m
1 stop
American Airlines Logo
1:48 pm - 11:45 pm
GUA
-
TYS
8h 57m
1 stop
$664American Airlines
Thu, Sep 10 - Wed, Sep 16
American Airlines Logo
7:30 am - 1:20 pm
TYS
-
GUA
7h 50m
1 stop
American Airlines Logo
7:00 am - 9:58 pm
GUA
-
TYS
12h 58m
1 stop
$683American Airlines
Thu, Sep 10 - Wed, Sep 16
American Airlines Logo
7:15 am - 6:29 pm
TYS
-
GUA
13h 14m
2 stops
American Airlines Logo
7:00 am - 9:58 pm
GUA
-
TYS
12h 58m
1 stop
$687American Airlines
Fri, Sep 18 - Sat, Sep 19
American Airlines Logo
6:15 am - 10:56 am
TYS
-
GUA
6h 41m
1 stop
American Airlines Logo
11:56 am - 11:22 pm
GUA
-
TYS
9h 26m
1 stop
$713American Airlines
Fri, Sep 18 - Sat, Sep 19
American Airlines Logo
6:00 am - 1:20 pm
TYS
-
GUA
9h 20m
1 stop
American Airlines Logo
2:21 pm - 10:38 am
GUA
-
TYS
18h 17m
2 stops
$717American Airlines
Sun, Nov 8 - Thu, Nov 12
American Airlines Logo
5:07 pm - 10:37 am
TYS
-
GUA
18h 30m
1 stop
American Airlines Logo
7:00 am - 9:31 pm
GUA
-
TYS
13h 31m
2 stops
$732American Airlines
Sat, Aug 15 - Fri, Sep 4
United Airlines Logo
7:00 am - 6:49 pm
TYS
-
GUA
13h 49m
2 stops
United Airlines Logo
1:30 am - 11:52 am
GUA
-
TYS
8h 22m
1 stop
$737United Airlines
Mon, Nov 2 - Mon, Nov 16
American Airlines Logo
6:00 am - 10:37 am
TYS
-
GUA
5h 37m
1 stop
American Airlines Logo
11:37 am - 10:54 pm
GUA
-
TYS
10h 17m
2 stops
$738American Airlines
Sat, Aug 15 - Sat, Sep 5
American Airlines Logo
5:15 am - 7:34 pm
TYS
-
GUA
16h 19m
2 stops
American Airlines Logo
2:23 pm - 11:06 am
GUA
-
TYS
18h 43m
2 stops
$741American Airlines
Sun, Nov 8 - Thu, Nov 12
American Airlines Logo
5:07 pm - 10:37 am
TYS
-
GUA
18h 30m
1 stop
American Airlines Logo
7:00 am - 9:31 pm
GUA
-
TYS
13h 31m
2 stops
$742American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Guatemala City flights

Get data-powered insights and trends into flights from Knoxville to Guatemala City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Guatemala City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Knoxville to Guatemala City were found on American Airlines ($664) and United Airlines ($737).

Good to know

Cheapest flight$483
Flight from Knoxville to Guatemala City

When to book flights from Knoxville to Guatemala City

Are your dates flexible? Find out the best times to travel from Knoxville to Guatemala City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Guatemala City

  • What is the cheapest flight from Knoxville to Guatemala City?

    In the last 5 days, the lowest price for a flight from Knoxville to Guatemala City was $483 for a one-way ticket and $664 for a round-trip.

  • Do I need a passport to fly between Knoxville and Guatemala City?

    Yes, you’ll need a passport to travel to Guatemala City from Knoxville.

  • Which aircraft models fly most regularly from Knoxville to Guatemala City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Guatemala City?

    oneworld is the only airline alliance operating flights between Knoxville and Guatemala City.

  • How does KAYAK find such low prices on flights from Knoxville to Guatemala City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Guatemala City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Guatemala City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guatemala City from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Guatemala City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guatemala City with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and GUA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Guatemala City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guatemala City from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Guatemala City

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Guatemala City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Guatemala City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11766 reviews
7.2Comfort
6.4Food
7.5Boarding
6.8Entertainment
7.9Crew
Airline reviews

Air condition was not working for long both after boarding and also after landing ; unbearably hot and suffocating

4.0 OkayAbhisek, Apr 2026
BNA - DFW
Read more American Airlines reviews

Air condition was not working for long both after boarding and also after landing ; unbearably hot and suffocating

It was canceled at the last minute. While I was literally at the airport. Messed my entire trip up.

Flight was on-time, boarding was flawless and the crew was friendly.

Not to have gotten delayed by 2+ hours for the fourth straight American flight. They're the worst.

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

This was a horrible American Airlines experience, and it discourages me from flying with them again. It may have stemmed from a mechanical delay, but it appeared that the team was unprepared to respond to the delay. After boarding, we waited an hour before finally taking off. After landing at our destination, we waited an additional hour on the tarmac waiting for a gate (at 8:00pm) to be assigned and cleared. The flight crew did their best, but they were clearly tired and also ready to be done for the day. Because of the delay, I missed a connecting flight. It was a very poor experience.

Fantastic! If it had not been for a check-in agent in Knoxville I may have not gotten my passes on British Airways. I couldn’t check-in online because British Airways had messed us the info on my tickets to London & Inverness. AA’s was great! British Airways was a continuous series of delays and frustrations.

Wheelchair was waiting for me,changed to a better seat which was great as it's hard for me to walk

Everything you need to know for your flight from Knoxville to Guatemala City

Information on your arrival and departure airports