MFR - SNA

$79 Find Cheap Flights from Medford to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Santa Ana departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Santa Ana, as well as popular online travel agencies
Travelers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$144
Overall average: $160
Allegiant Air
Sun 3/15Thu 3/19
MFR - SNA • Non-stop
Cheapest one-way
$79
Typical prices: $138-$163
Allegiant Air
Sun 2/22
MFR - SNA • Non-stop
Top airlines
Allegiant Air
Cheapest • from $144 (round-trip)
Alaska Airlines
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 42% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 36% price drop
April
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
2 days a week
There are direct flights from Medford to Santa Ana 2 days a week: Thu, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Ana!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medford to Santa Ana (MFR-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Santa Ana

Sun, Mar 15 - Thu, Mar 19
Allegiant Air Logo
3:35 pm - 5:36 pm
MFR
-
SNA
2h 01mnonstop
Allegiant Air Logo
6:26 pm - 8:30 pm
SNA
-
MFR
2h 04mnonstop
$144Allegiant Air
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
3:35 pm - 5:36 pm
MFR
-
SNA
2h 01mnonstop
Multiple Airlines Logo
6:45 am - 2:45 pm
SNA
-
MFR
8h 00m
1 stop
$191Multiple Airlines
Sat, Apr 4 - Wed, Apr 8
United Airlines Logo
2:12 pm - 8:55 pm
MFR
-
SNA
6h 43m
1 stop
United Airlines Logo
7:15 am - 11:48 am
SNA
-
MFR
4h 33m
1 stop
$197United Airlines
Sun, Apr 26 - Thu, Apr 30
Multiple Airlines Logo
9:12 pm - 6:11 pm
MFR
-
SNA
20h 59m
1 stop
Multiple Airlines Logo
6:18 pm - 8:22 pm
SNA
-
MFR
2h 04mnonstop
$214Multiple Airlines
Thu, Mar 19 - Sun, Mar 22
Allegiant Air Logo
3:35 pm - 5:36 pm
MFR
-
SNA
2h 01mnonstop
Allegiant Air Logo
6:26 pm - 8:30 pm
SNA
-
MFR
2h 04mnonstop
$220Allegiant Air
Thu, Feb 19 - Thu, Feb 26
Allegiant Air Logo
11:25 am - 1:30 pm
MFR
-
SNA
2h 05mnonstop
Allegiant Air Logo
2:19 pm - 4:21 pm
SNA
-
MFR
2h 02mnonstop
$222Allegiant Air
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
9:20 pm - 12:27 pm
MFR
-
SNA
15h 07m
1 stop
Multiple Airlines Logo
6:45 am - 2:45 pm
SNA
-
MFR
8h 00m
1 stop
$223Multiple Airlines
Sun, Apr 26 - Thu, Apr 30
Multiple Airlines Logo
9:12 pm - 1:44 pm
MFR
-
SNA
16h 32m
2 stops
Multiple Airlines Logo
6:18 pm - 8:22 pm
SNA
-
MFR
2h 04mnonstop
$247Multiple Airlines
Sun, Apr 26 - Thu, Apr 30
Allegiant Air Logo
3:29 pm - 5:28 pm
MFR
-
SNA
1h 59mnonstop
Allegiant Air Logo
6:18 pm - 8:22 pm
SNA
-
MFR
2h 04mnonstop
$250Allegiant Air
Sat, Mar 14 - Wed, Apr 1
Delta Logo
11:13 am - 6:22 pm
MFR
-
SNA
7h 09m
1 stop
Delta Logo
11:05 am - 4:36 pm
SNA
-
MFR
5h 31m
1 stop
$258Delta
Booking Insights

KAYAK's insights & trends for Medford to Santa Ana flights

Get data-powered insights and trends into flights from Medford to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medford to John Wayne (Santa Ana)?

The average price of all round-trip flights from Medford to Santa Ana clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Medford to John Wayne (Santa Ana), look for departures on Mondays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from John Wayne (Santa Ana), Monday is the cheapest day to fly and Tuesday is the most expensive.

What is the cheapest month to fly from Medford to Santa Ana?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medford to Santa Ana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medford to Santa Ana is May, where tickets cost $159 (return) on average. On the other hand, the most expensive months are September and December, where the average cost of round-trip tickets is $387 and $338 respectively.

How far in advance should I book a flight from Medford to Santa Ana?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medford to Santa Ana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medford to Santa Ana, you should book around 3 weeks before departure, which saves you about 42% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$79
Best time to beat the crowds but there is an average 17% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Medford to John Wayne (Santa Ana)

When to book flights from Medford to Santa Ana

Are your dates flexible? Find out the best times to travel from Medford to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to John Wayne (Santa Ana)

  • What is the cheapest flight from Medford to Santa Ana?

    In the last 3 days, the lowest price for a flight from Medford to Santa Ana was $79 for a one-way ticket and $144 for a round-trip.

  • Do I need a passport to fly between Medford and John Wayne (Santa Ana)?

    No, a passport isn't needed to fly from Medford to John Wayne (Santa Ana). However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Medford to John Wayne (Santa Ana)?

    Medford airport is called Medford and the only airport in John Wayne (Santa Ana) is Santa Ana J. Wayne/Orange Cnty.

  • Which airlines offer Wi-Fi service onboard planes from Medford to John Wayne (Santa Ana)?

    Only Alaska Airlines offers inflight Wi-Fi service on the Medford to John Wayne (Santa Ana) flight route.

  • Which aircraft models fly most regularly from Medford to John Wayne (Santa Ana)?

    The Airbus A319 is the aircraft model that flies most regularly on the Medford to John Wayne (Santa Ana) flight route.

  • Which airline alliances offer flights from Medford to John Wayne (Santa Ana)?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Medford and John Wayne (Santa Ana), with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Medford to John Wayne (Santa Ana)?

    You can catch a nonstop flight from Medford to John Wayne (Santa Ana) on on Thursday, and Sunday.

  • Which is the best airline for flights from Medford to Santa Ana, Alaska Airlines or Delta?

    The two airlines most popular with KAYAK users for flights from Medford to Santa Ana are Alaska Airlines and Delta. With an average price for the route of $383 and an overall rating of 8.0, Alaska Airlines is the most popular choice. Delta is also a great choice for the route, with an average price of $456 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Medford to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Medford with another airline. Booking your flights between Medford and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Medford to Santa Ana

  • Looking for a cheap flight? 25% of our users found flights on this route for $127 or less one-way and $147 or less round-trip.

Prefer to fly direct from Medford to John Wayne (Santa Ana)?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medford to Santa Ana J. Wayne/Orange Cnty.
Find which airlines fly direct from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport, which days they fly and book direct flights.

Direct departures

Medford to Santa Ana J. Wayne/Orange Cnty

Thursday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Santa Ana J. Wayne/Orange Cnty to Medford

Thursday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 4 airlines serving from Medford to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Medford to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 11834 reviews
7.0Entertainment
7.1Food
8.1Boarding
8.5Crew
7.8Comfort
Airline reviews

Alaska used to be a top notch airline. With it's growth it is now in line with the big airlines. Not bad, not great.

6.0 GoodJack, Feb 2026
PDX - SFO
Read more Alaska Airlines reviews

Alaska used to be a top notch airline. With it's growth it is now in line with the big airlines. Not bad, not great.

Great. I did have a little issue getting into the Lounge, which is likely more an American Airlines issue. I did not carry my physical AAdvantage Executive credit card with me on this trip, which Admirals Club membership is a part of the benefits of having this card. The instructions on the AA website and the Citi cards website make it seem like you don't need the physical card, as both sites state you can enter with your boarding pass and driver's license. But both lounges said you were required to present the physical card (and not the digital version, via Apple Pay), as only the physical card says "Admirals Club" on the back.I also do not have a physical Admirals Club membership card, so while both lounges eventually let me in, both denied me entrance initially for this reason.

I paid for wifi and it never worked... it was miserable. I couldn't access my shared files to work on the plane, it didn't work on my phone. I paid for nothing but frustration and continual refreshing, hoping it would work

Everything from the time I booked my flight through to the end when I got home was smooth and wonderful. Service was great, the flight attendants were attentive and there were no outstanding delays.

Delayed and no entertainment? I also forgot my headphones and immediately reported it and have not heard back yet.

The crew was very friendly. Boarding was quick and efficient.

On time, good boarding process very quick. Clean planes. Planes are tight, not much leg room ( i am only 5'8"). Some attendants are moving through aisles fiercely and pushing passengers. Got yelled for a tiny man bag that it is an extra personal tem ( size of a wallet) Wi-Fi on the plane does not work well with android phones.

There was no food or entertainment, thus thus the neutral rating.

The flight was excellent and very friendly and helpful staff. Will travel again and recommend to friends. Thank you

we waited for 50 minutes to check a bag and missed a flight. do better.

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

Food was surprisingly good but the WiFi was not great

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Flight was late - I was downgraded from first class to coach

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Plane boarded early a quickly, was mostly full. We left close to on time. And landed early.

7 hours delayed due to operational issues on United’s end. Basically laziness.

Great flight. Friendly staff. Free snacks and drinks would be nice. I would love fewer taxes and fees added on.

My 90 year old father flew with me. He needed wheel chair assistance and is nearly deaf. The staff was amazing with him.

It was fine. Nobody was outstandingly friendly but no one was rude and everything was smooth . The captain thanked us for flying but no one greeted me as I walked on the plane or as I exited which is the least they could do lol

Clean, friendly, roomy. But check-in from the phone link was terrible. Repeated attempts wouldn’t save at the final step. Just kept spinning! It was very frustrating. Finally, I used the app (vs website link) to check-in which worked very smoothly on the first attempt.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

Excellent flight and even arrived 23 min early. No entertainment , or wi fi on board, but I downloaded a couple of movies beforehand which kept me entertained. Really like flying Allegiant airlines.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

I love how they show love to their customers and care about them too.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Everything you need to know for your flight from Medford to Santa Ana

Information on your arrival and departure airports