MFR - SNA

$129 Find Cheap Flights from Medford to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Santa Ana departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Santa Ana, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Medford to Santa Ana (MFR-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Santa Ana

Sun, Nov 16 - Sun, Nov 23
Allegiant Air Logo
10:55 am - 12:57 pmMFR-SNA
2h 02mnonstop
Allegiant Air Logo
6:58 pm - 9:01 pmSNA-MFR
2h 03mnonstop
$155Allegiant Air
Find Deal
Thu, Feb 19 - Sun, Feb 22
Allegiant Air Logo
11:25 am - 1:30 pmMFR-SNA
2h 05mnonstop
Allegiant Air Logo
2:20 pm - 4:23 pmSNA-MFR
2h 03mnonstop
$192Allegiant Air
Find Deal
Tue, Dec 23 - Tue, Dec 30
Multiple Airlines Logo
8:14 pm - 10:16 amMFR-SNA
14h 02m1 stop
Multiple Airlines Logo
5:11 pm - 7:19 pmSNA-MFR
2h 08mnonstop
$199Multiple Airlines
Find Deal
Wed, Jan 28 - Sun, Feb 1
Multiple Airlines Logo
12:39 pm - 5:18 pmMFR-SNA
4h 39m1 stop
Multiple Airlines Logo
6:23 pm - 8:31 pmSNA-MFR
2h 08mnonstop
$208Multiple Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Delta Logo
5:23 pm - 10:21 pmMFR-SNA
4h 58m1 stop
Delta Logo
3:10 pm - 11:02 pmSNA-MFR
7h 52m1 stop
$247Delta
Find Deal
Fri, Jan 23 - Mon, Jan 26
American Airlines Logo
3:00 pm - 9:49 pmMFR-SNA
6h 49m1 stop
American Airlines Logo
1:24 pm - 7:38 pmSNA-MFR
6h 14m1 stop
$281American Airlines
Find Deal
Fri, Jan 2 - Wed, Jan 7
Alaska Airlines Logo
3:47 pm - 9:25 amMFR-SNA
17h 38m1 stop
Alaska Airlines Logo
1:55 pm - 10:49 pmSNA-MFR
8h 54m1 stop
$292Alaska Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Alaska Airlines Logo
3:45 pm - 10:26 pmMFR-SNA
6h 41m1 stop
Alaska Airlines Logo
6:45 am - 3:29 pmSNA-MFR
8h 44m2 stops
$296Alaska Airlines
Find Deal
Thu, Feb 26 - Sat, Mar 7
Delta Logo
5:20 pm - 10:38 pmMFR-SNA
5h 18m1 stop
Delta Logo
7:30 am - 2:33 pmSNA-MFR
7h 03m1 stop
$298Delta
Find Deal
Fri, Jan 16 - Sun, Jan 18
American Airlines Logo
5:32 am - 12:34 pmMFR-SNA
7h 02m1 stop
American Airlines Logo
12:38 pm - 7:38 pmSNA-MFR
7h 00m1 stop
$312American Airlines
Find Deal

Everything you should know

Top airlines
Allegiant Air
Cheapest • from $155 (round-trip)
Alaska Airlines
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 34% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 42% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
4 days a week
There are direct flights from Medford to Santa Ana 4 days a week: Tue, Thu, Fri, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Cheapest round-trip
$155
Overall average: $217
Allegiant Air
Sun 11/16Sun 11/23
MFR - SNA • Non-stop
Cheapest one-way
$113
Typical prices: $130-$290
Allegiant Air
Sun 11/9
MFR - SNA • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Ana!
Booking Insights

KAYAK's insights & trends for Medford to Santa Ana flights

Get data-powered insights and trends into flights from Medford to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medford to John Wayne (Santa Ana)?

The average price of all round-trip flights from Medford to Santa Ana clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Medford to John Wayne (Santa Ana), look for departures on Saturdays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from John Wayne (Santa Ana), Thursday is the cheapest day to fly and Tuesday is the most expensive.

What is the cheapest month to fly from Medford to Santa Ana?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medford to Santa Ana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medford to Santa Ana is May, where tickets cost $159 (return) on average. On the other hand, the most expensive months are July and September, where the average cost of round-trip tickets is $391 and $387 respectively.

How far in advance should I book a flight from Medford to Santa Ana?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medford to Santa Ana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medford to Santa Ana, you should book around 3 weeks before departure, which saves you about 34% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$113
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly and prices are also 22% lower on average.
Flight from Medford to John Wayne (Santa Ana)

When to book flights from Medford to Santa Ana

Are your dates flexible? Find out the best times to travel from Medford to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to John Wayne (Santa Ana)

  • What is the cheapest flight from Medford to Santa Ana?

    In the last 3 days, the lowest price for a flight from Medford to Santa Ana was $113 for a one-way ticket and $155 for a round-trip.

  • Do I need a passport to fly between Medford and John Wayne (Santa Ana)?

    No, a passport isn't needed to fly from Medford to John Wayne (Santa Ana). However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Medford to John Wayne (Santa Ana)?

    Medford airport is called Medford and the only airport in John Wayne (Santa Ana) is Santa Ana J. Wayne/Orange Cnty.

  • Which airlines offer Wi-Fi service onboard planes from Medford to John Wayne (Santa Ana)?

    Only Alaska Airlines offers inflight Wi-Fi service on the Medford to John Wayne (Santa Ana) flight route.

  • Which aircraft models fly most regularly from Medford to John Wayne (Santa Ana)?

    The Airbus A319 is the aircraft model that flies most regularly on the Medford to John Wayne (Santa Ana) flight route.

  • Which airline alliances offer flights from Medford to John Wayne (Santa Ana)?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Medford and John Wayne (Santa Ana), with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Medford to John Wayne (Santa Ana)?

    You can catch a nonstop flight from Medford to John Wayne (Santa Ana) on on Monday, Tuesday, Thursday, Saturday, and Sunday.

  • Which is the best airline for flights from Medford to Santa Ana, Alaska Airlines or Delta?

    The two airlines most popular with KAYAK users for flights from Medford to Santa Ana are Alaska Airlines and Delta. With an average price for the route of $374 and an overall rating of 8.0, Alaska Airlines is the most popular choice. Delta is also a great choice for the route, with an average price of $373 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Medford to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Medford with another airline. Booking your flights between Medford and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Medford to Santa Ana

  • Looking for a cheap flight? 25% of our users found flights on this route for $87 or less one-way and $160 or less round-trip.

Prefer to fly direct from Medford to John Wayne (Santa Ana)?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medford to Santa Ana J. Wayne/Orange Cnty.
Find which airlines fly direct from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport, which days they fly and book direct flights.

Direct departures

Medford to Santa Ana J. Wayne/Orange Cnty

Tuesday

Allegiant Air

Allegiant Air

Thursday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Santa Ana J. Wayne/Orange Cnty to Medford

Tuesday

Allegiant Air

Allegiant Air

Thursday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 4 airlines serving from Medford to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Medford to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 11234 reviews
7.1Food
8.5Crew
7.8Comfort
8.1Boarding
7.0Entertainment
Airline reviews

This was more with the third party booking through Kayak but my KTN for Pre-TSA, even though I entered it, wasn't assigned to my ticket when I got to the airport. I had to go through regular security. Also the Alaska app had trouble loading my ticket in the first place and I had to ask for it to be printed. Alaska Airlines was great but wanted you to know about this hiccup in the ticketing interface.

8.0 ExcellentJ, Oct 2025PDX - SFO
Read more Alaska Airlines reviews

This was more with the third party booking through Kayak but my KTN for Pre-TSA, even though I entered it, wasn't assigned to my ticket when I got to the airport. I had to go through regular security. Also the Alaska app had trouble loading my ticket in the first place and I had to ask for it to be printed. Alaska Airlines was great but wanted you to know about this hiccup in the ticketing interface.

Food and entertainment not applicable - standard drinks and cinnamon cookies; crew did not do a song and dance for us so no entertainment. I like the slightly better leg room than American Airlines - at least it felt that way. Flight crew and atmosphere seemed more welcoming than American, too.

When I bought my tickets I up great my seats for extra $104 each seats 8A and 8B in the way back from Portland to Palm Springs they gave me the seats 15. I thought it was for round trip same seats . So I was very disappointed ☹️

Alaska Airlines adds time to flight time to make up for late departures. Also Alaska Airlines destroyed my suitcase and I had to buy another suitcase for return flight. Very frustrating and not sure I would fly Alaska Airlines again.

The vibe and energy of the Alaska staff on ground in Redmond is some of the best we’ve seen!

Staff inside Portland terminal were rude, made us fell rushed and not at all accommodating to seniors. For this alone I will probably never booked from them again.

It was fine—the seats are not very comfortable and the aisles are very narrow. Nothing different from other airlines

Well the flight being delayed multiple time really was frustrating. But the crew and flight was good.

generally good. No snacks or drinks on the flight 3379 from Portland to San Jose, CA. Sad.

Everything except for the lack of a choice of the snack provided was great.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

Food was surprisingly good but the WiFi was not great

My flight was extremely cold. I had a jacket and a cover was left in each seat. The cover was extremely thin and I have a disability, fibromyalgia and arthrithis and AC air is the worst. I closed my vent and my husbands vent and it still was frigid. I asked the attendant if I could get another cover and she quickly almost dismissively and totally unconcerned stating, (I quote) (one per chair) and walked off so quickly that I didn't get a chance to explain to her that I literally have adisability. I didnt want to make a seen so I set on that flight for over 5 hours in pain, joints locking up and extremely uncomfortable. When my fibromyalgia flares up my joints not only ache but they will lock up also and it takes me days to get back to my regular self even though I take medication for it. I felt like it would not have hurt anyone at all for her to just give me an extra cover because I'm sure they have all types of medical issues in people that fly every day.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

7 hours delayed due to operational issues on United’s end. Basically laziness.

Flight was timely, relatively comfortable, with decent entertainment and food served. Only problem encountered was with the free messaging which I highly appreciate, but it did not work from iphone to non-iphones.

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

Check in was quick and easy during early hours. Flight was on time, and customer services was a plus.

The flight was comfortable with the exit row and great service

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

1. when we went to check in, our 2 first class seats had been CANCELED and the flight was sold out. This was done without our prior knowledge. It was all we could do to restore one first class seat for my wife and I flew economy. 2, Our flight home was scheduled to leave at 10:30 pm. Due to tsunami warnings, the roads were closed and our flight status was uncertain as to whether it would leave as scheduled. It was announced that it would now leave at 11:20 pm and the roads were now open since the tsunami had come and gone. We made a mad dash to the airport and checked in. Delays were announced at 12:30 pm, 1:30 am, 2:30 am and at 3:30 am it was canceled. Since this was a flight due to natural (tsunami) causes, there was no compensation. We were told to return at 1:00 pm the next day and our baggage would be kept on the plane since the same plane was going to leave at 1:00 pm. We had to return to our hotel for the rest of the night. The same plane did not leave at 1:00 pm and our baggage was gone! All in all, it was a miserable performance by UA. Information was hard to obtain and no one knew what was going on and what was going to happen. Hundreds of passengers slept on the floor, chairs, etc. No food and no water was made available to the passengers. It was a situation where UA could care less what was going on. As a one million mile flyer, I had not experienced anything like this before and it was hugely disappointing!

Boarded plane and then delayed 1.5 hours while on the plane

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

Everything you need to know for your flight from Medford to Santa Ana

Information on your arrival and departure airports

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