MFR - SNA

$86 Find Cheap Flights from Medford to John Wayne (Santa Ana)

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Santa Ana departing on 7/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to John Wayne (Santa Ana)

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to John Wayne (Santa Ana), as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to John Wayne (Santa Ana), as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$139
Typical prices: $153-$287
Allegiant Air
Mon 10/26Fri 10/30
MFR - SNA • Non-stop
Cheapest non-stop
$170
Typical prices: $176-$277
Allegiant Air
Fri 8/14Mon 8/17
MFR - SNA • Non-stop
Nonstop flights
Mon, Fri
You can fly direct with Allegiant Air. Average duration is 2h 01m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 53% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 37% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Ana!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medford to Santa Ana (MFR-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Santa Ana

Mon, Oct 26 - Fri, Oct 30
Allegiant Air Logo
3:04 pm - 5:02 pm
MFR
-
SNA
1h 58mnonstop
Allegiant Air Logo
6:36 pm - 8:35 pm
SNA
-
MFR
1h 59mnonstop
$139Allegiant Air
Fri, Aug 14 - Mon, Aug 17
Allegiant Air Logo
3:38 pm - 5:39 pm
MFR
-
SNA
2h 01mnonstop
Allegiant Air Logo
6:29 pm - 8:27 pm
SNA
-
MFR
1h 58mnonstop
$170Allegiant Air
Fri, Aug 14 - Mon, Aug 17
Multiple Airlines Logo
9:17 pm - 12:31 pm
MFR
-
SNA
15h 14m
1 stop
Multiple Airlines Logo
6:29 pm - 8:27 pm
SNA
-
MFR
1h 58mnonstop
$171Multiple Airlines
Fri, Aug 7 - Fri, Aug 14
Multiple Airlines Logo
9:17 pm - 12:31 pm
MFR
-
SNA
15h 14m
1 stop
Multiple Airlines Logo
6:29 pm - 8:27 pm
SNA
-
MFR
1h 58mnonstop
$179Multiple Airlines
Mon, Jul 27 - Mon, Aug 3
Multiple Airlines Logo
9:11 pm - 3:28 pm
MFR
-
SNA
18h 17m
1 stop
Multiple Airlines Logo
6:27 pm - 8:21 pm
SNA
-
MFR
1h 54mnonstop
$187Multiple Airlines
Mon, Jul 27 - Fri, Jul 31
Allegiant Air Logo
3:36 pm - 5:37 pm
MFR
-
SNA
2h 01mnonstop
Allegiant Air Logo
6:27 pm - 8:21 pm
SNA
-
MFR
1h 54mnonstop
$192Allegiant Air
Fri, Aug 14 - Mon, Aug 17
Allegiant Air Logo
3:38 pm - 5:39 pm
MFR
-
SNA
2h 01mnonstop
Allegiant Air Logo
6:29 pm - 8:27 pm
SNA
-
MFR
1h 58mnonstop
$195Allegiant Air
Mon, Jul 27 - Mon, Aug 3
Multiple Airlines Logo
9:11 pm - 3:28 pm
MFR
-
SNA
18h 17m
1 stop
Multiple Airlines Logo
6:27 pm - 8:21 pm
SNA
-
MFR
1h 54mnonstop
$203Multiple Airlines
Mon, Jul 27 - Thu, Aug 6
Multiple Airlines Logo
9:11 pm - 3:28 pm
MFR
-
SNA
18h 17m
1 stop
Multiple Airlines Logo
7:53 pm - 2:48 pm
SNA
-
MFR
18h 55m
1 stop
$204Multiple Airlines
Mon, Oct 26 - Fri, Oct 30
Multiple Airlines Logo
8:41 pm - 3:03 pm
MFR
-
SNA
18h 22m
1 stop
Multiple Airlines Logo
6:36 pm - 8:35 pm
SNA
-
MFR
1h 59mnonstop
$211Multiple Airlines
Booking Insights

KAYAK's insights & trends for Medford to Santa Ana flights

Get data-powered insights and trends into flights from Medford to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medford to Santa Ana, California?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medford to Santa Ana, California departing in October.

What’s the cheapest day of the week to fly from Medford to John Wayne (Santa Ana)?

The average price of all round-trip flights from Medford to Santa Ana clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Medford to John Wayne (Santa Ana), look for departures on Mondays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from John Wayne (Santa Ana), Thursday is the cheapest day to fly and Tuesday is the most expensive.

What is the cheapest month to fly from Medford to John Wayne (Santa Ana)?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medford to Santa Ana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medford to John Wayne (Santa Ana) is April, where tickets cost $161 (return) on average. On the other hand, the most expensive months are September and February, where the average cost of round-trip tickets is $411 and $386 respectively.

How far in advance should I book a flight from Medford to John Wayne (Santa Ana)?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medford to Santa Ana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medford to John Wayne (Santa Ana), you should book around 3 weeks before departure, which saves you about 53% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$86
Best time to beat the crowds but there is an average 51% increase in price.
Most popular time to fly and prices are also 29% lower on average.
Flight from Medford to John Wayne (Santa Ana)

When to book flights from Medford to Santa Ana

Are your dates flexible? Find out the best times to travel from Medford to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to John Wayne (Santa Ana)

  • How many flights are there between Medford and John Wayne (Santa Ana) per day?

    There is a maximum of 1 nonstop flight a day that takes off from Medford and lands in John Wayne (Santa Ana), with an average flight time of 2h 01m. The most common departure time is 3:00 pm and most flights take off in the afternoon. Each week, there are 2 flights.

  • What is the cheapest flight from Medford to John Wayne (Santa Ana)?

    In the last 5 days, the lowest price for a flight from Medford to John Wayne (Santa Ana) was $86 for a one-way ticket and $139 for a round-trip.

  • Do I need a passport to fly between Medford and John Wayne (Santa Ana)?

    No, a passport isn't needed to fly from Medford to John Wayne (Santa Ana). However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Medford to John Wayne (Santa Ana)?

    Medford airport is called Medford and the only airport in John Wayne (Santa Ana) is Santa Ana J. Wayne/Orange Cnty.

  • Which airlines offer Wi-Fi service onboard planes from Medford to John Wayne (Santa Ana)?

    Alaska Airlines, and American Airlines offer inflight Wi-Fi service on the Medford to John Wayne (Santa Ana) flight route.

  • Which aircraft models fly most regularly from Medford to John Wayne (Santa Ana)?

    The Airbus A319 is the aircraft model that flies most regularly on the Medford to John Wayne (Santa Ana) flight route.

  • Which airline alliances offer flights from Medford to John Wayne (Santa Ana)?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Medford and John Wayne (Santa Ana), with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Medford to John Wayne (Santa Ana)?

    You can catch a nonstop flight from Medford to John Wayne (Santa Ana) on on Monday, and Friday.

  • Which is the best airline for flights from Medford to John Wayne (Santa Ana), Alaska Airlines or Delta?

    The two airlines most popular with KAYAK users for flights from Medford to John Wayne (Santa Ana) are Alaska Airlines and Delta. With an average price for the route of $408 and an overall rating of 7.9, Alaska Airlines is the most popular choice. Delta is also a great choice for the route, with an average price of $182 and an overall rating of 7.8.

  • How does KAYAK find such low prices on flights from Medford to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Medford with another airline. Booking your flights between Medford and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Medford to John Wayne (Santa Ana)

  • Looking for a cheap flight? 25% of our users found flights on this route for $118 or less one-way and $176 or less round-trip.

Prefer to fly direct from Medford to John Wayne (Santa Ana)?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medford to Santa Ana J. Wayne/Orange Cnty.
Find which airlines fly direct from Medford Airport to Santa Ana J. Wayne/Orange Cnty Airport, which days they fly and book direct flights.

Direct departures

Medford to Santa Ana J. Wayne/Orange Cnty

Monday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Santa Ana J. Wayne/Orange Cnty to Medford

Monday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 4 airlines serving from Medford to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Medford to John Wayne (Santa Ana). Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
Alaska AirlinesOverall score based on 12603 reviews
8.5Crew
8.1Boarding
7.0Entertainment
7.8Comfort
7.1Food
Airline reviews

My boarding passes were pulled from my Apple wallet and my 3 family members who were all sitting together in the same row all got put middle seats and were one of the last to board and barely were able to get our bags in the luggage bins.

2.0 MediocreAnonymous, Jun 2026
SEA - SNA
Read more Alaska Airlines reviews

My boarding passes were pulled from my Apple wallet and my 3 family members who were all sitting together in the same row all got put middle seats and were one of the last to board and barely were able to get our bags in the luggage bins.

I paid for the WiFi and it didn’t work during the whole flight

I paid for wifi and it never worked... it was miserable. I couldn't access my shared files to work on the plane, it didn't work on my phone. I paid for nothing but frustration and continual refreshing, hoping it would work

The flight was excellent and very friendly and helpful staff. Will travel again and recommend to friends. Thank you

They canceled my flight with only a couple hours before checking in at the airport and offered no alternatives to get home.

A very good experience - all staff was friendly and helpful.

Food and entertainment not applicable - standard drinks and cinnamon cookies; crew did not do a song and dance for us so no entertainment. I like the slightly better leg room than American Airlines - at least it felt that way. Flight crew and atmosphere seemed more welcoming than American, too.

At the Portland airport, Alaska Airlines has put in a system where you have to create your own bag tag, then put your own suitcase onto a scale to weigh it. The day we were there, the system was not working properly, and we kept on being told to go onto different lines so it took us approximately 45 minutes to check our bag in. I do not work for the airlines why am I subjected to doing this? How all these companies are shifting their work onto people who have paid good money for their products is crazy. And then the system that the customers are supposed to use don't work properly..

The staff from check-in counter to the flight crew were great. Flight was right on schedule. 10/10

I APPRECIATED THAT THEY CALLED ME TO LET ME KNOW THAT I NEEDED TO BOARD ASAP AS I THOUGHT I STILL HAD AFEW MINUTES LEFT TO FINISH MY BLOODY MARY.

Crew was real good, flight was smooth and came in early.

Love me some Delta. One of the few airlines to recognize and support veterans. Easy boarding, flight was on time and arrived early and the flight attendants were excellent on this flight.

We sat on the runway for over an hour before departure. That was unwelcome.

Flight delayed four separate times. I’m now one hour hours late to landing.

worst flight ever from Delta, it got delayed and kept on delaying..

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

They separated our seats and moved us to the back of the plane. Hundreds of dollars and thousands of miles used and this was my platinum member experience.

The flight was canceled two hours before departure, it took over five hours to rebook us on another flight.

Destroyed my suitcase. Tired of talking about it. Cancelling my unite mileage plus account.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight was delayed from take off because only one runway was operational in San Francisco.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Dinner was okay but the breakfast was not eatable on the flight San Francisco to Zurich.

The control panel for the seat back screen did not work at all after takeoff.

The crew was nice but the people going to Orange County are so entitled. Everyone thinks everything is suppose for be perfect for them. Tough crowd.

How they treated my luggage was horrible. And foods are not edible… Flight attendants were not listening my request. Etc

This is a no frills, get it done, efficient airline. The seat is a lawn chair. You better bring your own entertainment. If you want something other than water you need to pay for it. But they will get you to your destination quickly, on time, and then they will turn the flight around and go right back where they came from. Reliably. Couple times a week tops. If it fits into your schedule, you can’t get there cheaper or faster.

A three hour delay to board and then another hour on the tarmac because they couldn't get a tractor? Ugh.

Allegiant canceled the flight. The flight the next day was full. Allegiant did not provide any compensation besides a refund. Last time on Allegiant.

Seats were very uncomfortable and being charged for snacks and water.........

Allegiant actually impressed me, original inbound flight from PBG was so late they gave us a bird inbound from Des Moines and only left 1h late and gained 40 minutes back in the air. Comfortable flight with no frills but no complaints.

Flight was delayed. Crew was good but hot coffee was not available.

The flight was very delayed (in BOTH directions - outbound and returning). The flight was very very cramped. The plane taxi'd on the runway for a really long time, and I got claustrophobic being in such a tight seat. The pilot and crew both indicated that we were going to make up lost time due to the delay, but the plane arrived LATER than expected.

A foot rest for short legged people and a complimentary water would be nice.

The employees at the check-in counter said my disabled wife and I were going to be separated even though we picked seating together when we bought our tickets. They told us my wife would be seated in row 2 and I would be in row 8, because we bought our tickets from a third party. Fortunately the flight crew said: "No, you two need to be together, we'll fix this." Then they seated us together. We are 75 years old and flying is a challenge for us, so we appreciate all the help we can get. Your flight crew was awesome with us, and with the children on our flight as well. Thank You Allegent Air Lines! 🙂

I did not go on my trip. I requested a refund and still have not received it.

Everything you need to know for your flight from Medford to Santa Ana

Information on your arrival and departure airports