$105 Find Cheap Flights from Medford to John Wayne (Santa Ana) - Compare and Save

These are the earliest and latest flight times available from Medford to Santa Ana:

• Earliest: departs at 10:51 am and lands at 12:51 pm
• Latest: departs at 4:11 pm and lands at 6:11 pm.

The flight takes about 2h.

Three cabin classes are available on flights from Medford to Santa Ana:

• Economy Class
• Business Class
• First Class

A nonstop flight from Medford to Santa Ana takes 2h, covering 659 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Round-trip flights from Medford to Santa Ana range from $183 to $360, with an average of $253 over the past 12 months. Anything below $183 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 39% above the $253 route average. Book 23 weeks before departure for the lowest fares.

On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $185 round-trip, compared to $297 via a layover through Seattle/Tacoma Intl (SEA).

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $25–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A319 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Embraer 175 variants.

One-way fares from Medford to Santa Ana are currently higher than usual. Average one-way flight prices are about $209, which is 22% above the typical average for this route.

Santa Ana J. Wayne/Orange Cnty Airport (SNA) hosts 5 major car rental companies, with daily rates averaging $58 for economy cars. Top options include:

• Dollar
• Thrifty
• Hertz
• Budget
• Alamo

Flights from Medford to Santa Ana usually depart from Medford (MFR) and arrive at Santa Ana J. Wayne/Orange Cnty (SNA).

One-stop flights from Medford to Santa Ana most commonly connect through:

• San Francisco (SFO) - 34% of one-stop connections
• Portland (PDX) - 31% of one-stop connections
• Seattle/Tacoma Intl (SEA) - 28% of one-stop connections
• Las Vegas Harry Reid Intl (LAS) - 5% of one-stop connections

Yes. Flexible dates can save you up to 45% on flights from Medford to Santa Ana. Thursday is the cheapest departure day at $208 round-trip on average, while Wednesday is the most expensive at $378, a difference of $170.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Allegiant Air operates flights between Medford and Santa Ana.

Flying via San Francisco (SFO) gives the shortest average 1-stop total travel time at 4h 55m, compared with 5h 17m via Portland (PDX) and 5h 20m via Phoenix Sky Harbor Intl (PHX).

Some of the most popular sights in Santa Ana are Embassy Suites by Hilton Santa Ana Orange County Airport, Santa Ana Zoo and Old Orange County Courthouse. These are among the most viewed places in Santa Ana on KAYAK.