$123 Find Cheap Flights from John Wayne (Santa Ana) to Medford - Compare and Save

These are the earliest and latest flight times available from Santa Ana to Medford:

• Earliest: departs at 1:40 pm and lands at 3:44 pm
• Latest: departs at 7:02 pm and lands at 9:06 pm.

The flight takes about 2h 04m.

Two cabin classes are available on flights from Santa Ana to Medford:

• Economy Class
• First Class

A nonstop flight from Santa Ana to Medford takes 2h 04m, covering 659 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Round-trip flights from Santa Ana to Medford range from $171 to $390, with an average of $238 over the past 12 months. Anything below $171 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 42% above the $238 route average. Book 24 weeks before departure for the lowest fares.

On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $186 round-trip, compared to $295 via a layover through Las Vegas Harry Reid Intl (LAS).

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $25–$90 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A319 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Embraer 175 variants.

One-way fares from Santa Ana to Medford are currently higher than usual. Average one-way flight prices are about $224, which is 10% above the typical average for this route.

Medford Airport (MFR) hosts 5 major car rental companies, with daily rates averaging $79 for economy cars. Top options include:

• Budget
• Dollar
• Alamo
• Enterprise Rent-A-Car
• Avis

Flights from Santa Ana to Medford usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Medford (MFR).

One-stop flights from Santa Ana to Medford most commonly connect through:

• San Francisco (SFO) - 44% of one-stop connections
• Portland (PDX) - 28% of one-stop connections
• Seattle/Tacoma Intl (SEA) - 23% of one-stop connections
• Las Vegas Harry Reid Intl (LAS) - 5% of one-stop connections

Yes. Flexible dates can save you up to 59% on flights from Santa Ana to Medford. Thursday is the cheapest departure day at $184 round-trip on average, while Wednesday is the most expensive at $439, a difference of $255.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Allegiant Air operates flights between Santa Ana and Medford.

Flying via San Francisco (SFO) gives the shortest average 1-stop total travel time at 4h 51m, compared with 4h 52m via Portland (PDX) and 5h 50m via Seattle/Tacoma Intl (SEA).